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Items: 22

1.

Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension.

Kurosawa R, Satoh K, Kikuchi N, Kikuchi H, Saigusa D, Al-Mamun ME, Siddique MAH, Omura J, Satoh T, Sunamura S, Nogi M, Numano K, Miyata S, Uruno A, Kano K, Matsumoto Y, Doi T, Aoki J, Oshima Y, Yamamoto M, Shimokawa H.

Circ Res. 2019 Jul 19;125(3):309-327. doi: 10.1161/CIRCRESAHA.119.315229. Epub 2019 Jun 14.

PMID:
31195886
2.

Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing.

Supakul S, Yao K, Ochi H, Shimada T, Hashimoto K, Sunamura S, Mabuchi Y, Tanaka M, Akazawa C, Nakamura T, Okawa A, Takeda S, Sato S.

Int J Mol Sci. 2019 Mar 2;20(5). pii: E1079. doi: 10.3390/ijms20051079.

3.

Identification of Novel Therapeutic Targets for Pulmonary Arterial Hypertension.

Satoh K, Kikuchi N, Satoh T, Kurosawa R, Sunamura S, Siddique MAH, Omura J, Yaoita N, Shimokawa H.

Int J Mol Sci. 2018 Dec 17;19(12). pii: E4081. doi: 10.3390/ijms19124081. Review.

4.

Different roles of myocardial ROCK1 and ROCK2 in cardiac dysfunction and postcapillary pulmonary hypertension in mice.

Sunamura S, Satoh K, Kurosawa R, Ohtsuki T, Kikuchi N, Elias-Al-Mamun M, Shimizu T, Ikeda S, Suzuki K, Satoh T, Omura J, Nogi M, Numano K, Siddique MAH, Miyata S, Miura M, Shimokawa H.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7129-E7138. doi: 10.1073/pnas.1721298115. Epub 2018 Jul 9.

5.

Small GTP-Binding Protein GDP Dissociation Stimulator Prevents Thoracic Aortic Aneurysm Formation and Rupture by Phenotypic Preservation of Aortic Smooth Muscle Cells.

Nogi M, Satoh K, Sunamura S, Kikuchi N, Satoh T, Kurosawa R, Omura J, Elias-Al-Mamun M, Abdul Hai Siddique M, Numano K, Kudo S, Miyata S, Akiyama M, Kumagai K, Kawamoto S, Saiki Y, Shimokawa H.

Circulation. 2018 Nov 20;138(21):2413-2433. doi: 10.1161/CIRCULATIONAHA.118.035648.

PMID:
29921611
6.

Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension.

Kikuchi N, Satoh K, Kurosawa R, Yaoita N, Elias-Al-Mamun M, Siddique MAH, Omura J, Satoh T, Nogi M, Sunamura S, Miyata S, Saito Y, Hoshikawa Y, Okada Y, Shimokawa H.

Circulation. 2018 Aug 7;138(6):600-623. doi: 10.1161/CIRCULATIONAHA.117.033113.

PMID:
29636330
7.

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.

Hashimoto K, Ochi H, Sunamura S, Kosaka N, Mabuchi Y, Fukuda T, Yao K, Kanda H, Ae K, Okawa A, Akazawa C, Ochiya T, Futakuchi M, Takeda S, Sato S.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2204-2209. doi: 10.1073/pnas.1717363115. Epub 2018 Feb 12.

8.

Antiretroviral Therapy Containing HIV Protease Inhibitors Enhances Fracture Risk by Impairing Osteoblast Differentiation and Bone Quality.

Hirakawa H, Gatanaga H, Ochi H, Fukuda T, Sunamura S, Oka S, Takeda S, Sato S.

J Infect Dis. 2017 Jun 15;215(12):1893-1897. doi: 10.1093/infdis/jix246.

PMID:
28525596
9.

Activated TAFI Promotes the Development of Chronic Thromboembolic Pulmonary Hypertension: A Possible Novel Therapeutic Target.

Satoh T, Satoh K, Yaoita N, Kikuchi N, Omura J, Kurosawa R, Numano K, Al-Mamun E, Siddique MA, Sunamura S, Nogi M, Suzuki K, Miyata S, Morser J, Shimokawa H.

Circ Res. 2017 Apr 14;120(8):1246-1262. doi: 10.1161/CIRCRESAHA.117.310640. Epub 2017 Mar 13.

PMID:
28289017
10.

Prognostic Impacts of Plasma Levels of Cyclophilin A in Patients With Coronary Artery Disease.

Ohtsuki T, Satoh K, Omura J, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Sunamura S, Yaoita N, Aoki T, Tatebe S, Sugimura K, Takahashi J, Miyata S, Shimokawa H.

Arterioscler Thromb Vasc Biol. 2017 Apr;37(4):685-693. doi: 10.1161/ATVBAHA.116.308986. Epub 2017 Feb 2.

PMID:
28153875
11.

Histone deacetylase inhibitor panobinostat induces calcineurin degradation in multiple myeloma.

Imai Y, Ohta E, Takeda S, Sunamura S, Ishibashi M, Tamura H, Wang YH, Deguchi A, Tanaka J, Maru Y, Motoji T.

JCI Insight. 2016 Apr 21;1(5):e85061. doi: 10.1172/jci.insight.85061.

12.

Protective Roles of Endothelial AMP-Activated Protein Kinase Against Hypoxia-Induced Pulmonary Hypertension in Mice.

Omura J, Satoh K, Kikuchi N, Satoh T, Kurosawa R, Nogi M, Otsuki T, Kozu K, Numano K, Suzuki K, Sunamura S, Tatebe S, Aoki T, Sugimura K, Miyata S, Hoshikawa Y, Okada Y, Shimokawa H.

Circ Res. 2016 Jul 8;119(2):197-209. doi: 10.1161/CIRCRESAHA.115.308178. Epub 2016 May 23.

PMID:
27217398
13.

SmgGDS as a Crucial Mediator of the Inhibitory Effects of Statins on Cardiac Hypertrophy and Fibrosis: Novel Mechanism of the Pleiotropic Effects of Statins.

Kudo S, Satoh K, Nogi M, Suzuki K, Sunamura S, Omura J, Kikuchi N, Kurosawa R, Satoh T, Minami T, Ikeda S, Miyata S, Shimokawa H.

Hypertension. 2016 May;67(5):878-89. doi: 10.1161/HYPERTENSIONAHA.115.07089. Epub 2016 Mar 14.

PMID:
26975711
14.

Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice.

Suzuki K, Satoh K, Ikeda S, Sunamura S, Otsuki T, Satoh T, Kikuchi N, Omura J, Kurosawa R, Nogi M, Numano K, Sugimura K, Aoki T, Tatebe S, Miyata S, Mukherjee R, Spinale FG, Kadomatsu K, Shimokawa H.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):636-46. doi: 10.1161/ATVBAHA.115.306686. Epub 2016 Feb 25.

PMID:
26916734
15.

Circadian Clock Regulates Bone Resorption in Mice.

Xu C, Ochi H, Fukuda T, Sato S, Sunamura S, Takarada T, Hinoi E, Okawa A, Takeda S.

J Bone Miner Res. 2016 Jul;31(7):1344-55. doi: 10.1002/jbmr.2803. Epub 2016 Mar 4.

16.

RhoA/Rho-Kinase in the Cardiovascular System.

Shimokawa H, Sunamura S, Satoh K.

Circ Res. 2016 Jan 22;118(2):352-66. doi: 10.1161/CIRCRESAHA.115.306532. Review.

PMID:
26838319
17.

MicroRNA-145 regulates osteoblastic differentiation by targeting the transcription factor Cbfb.

Fukuda T, Ochi H, Sunamura S, Haiden A, Bando W, Inose H, Okawa A, Asou Y, Takeda S.

FEBS Lett. 2015 Oct 24;589(21):3302-8. doi: 10.1016/j.febslet.2015.09.024. Epub 2015 Oct 9.

18.

Rho-Kinase Inhibition During Early Cardiac Development Causes Arrhythmogenic Right Ventricular Cardiomyopathy in Mice.

Ellawindy A, Satoh K, Sunamura S, Kikuchi N, Suzuki K, Minami T, Ikeda S, Tanaka S, Shimizu T, Enkhjargal B, Miyata S, Taguchi Y, Handoh T, Kobayashi K, Kobayashi K, Nakayama K, Miura M, Shimokawa H.

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2172-84. doi: 10.1161/ATVBAHA.115.305872. Epub 2015 Aug 27.

PMID:
26315406
19.

Genetic determination of the cellular basis of the ghrelin-dependent bone remodeling.

Ma C, Fukuda T, Ochi H, Sunamura S, Xu C, Xu R, Okawa A, Takeda S.

Mol Metab. 2015 Jan 21;4(3):175-85. doi: 10.1016/j.molmet.2015.01.002. eCollection 2015 Mar.

20.

Sema3A regulates bone-mass accrual through sensory innervations.

Fukuda T, Takeda S, Xu R, Ochi H, Sunamura S, Sato T, Shibata S, Yoshida Y, Gu Z, Kimura A, Ma C, Xu C, Bando W, Fujita K, Shinomiya K, Hirai T, Asou Y, Enomoto M, Okano H, Okawa A, Itoh H.

Nature. 2013 May 23;497(7450):490-3. doi: 10.1038/nature12115. Epub 2013 May 5. Erratum in: Nature. 2013 Aug 29;500(7464):612.

PMID:
23644455
21.

Vitamin E decreases bone mass by stimulating osteoclast fusion.

Fujita K, Iwasaki M, Ochi H, Fukuda T, Ma C, Miyamoto T, Takitani K, Negishi-Koga T, Sunamura S, Kodama T, Takayanagi H, Tamai H, Kato S, Arai H, Shinomiya K, Itoh H, Okawa A, Takeda S.

Nat Med. 2012 Mar 4;18(4):589-94. doi: 10.1038/nm.2659. Erratum in: Nat Med. 2012 Sep;18(9):1445.

PMID:
22388090
22.

A microRNA regulatory mechanism of osteoblast differentiation.

Inose H, Ochi H, Kimura A, Fujita K, Xu R, Sato S, Iwasaki M, Sunamura S, Takeuchi Y, Fukumoto S, Saito K, Nakamura T, Siomi H, Ito H, Arai Y, Shinomiya K, Takeda S.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20794-9. doi: 10.1073/pnas.0909311106. Epub 2009 Nov 20.

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