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Items: 1 to 50 of 114

1.

The relationship between antecedent creatinine decreases and outcomes in patients undergoing hemodialysis.

Harada T, Sorimachi H, Obokata M, Sunaga H, Ishida H, Ito K, Ogawa T, Ando Y, Kurabayashi M, Negishi K.

Hemodial Int. 2019 Oct 21. doi: 10.1111/hdi.12794. [Epub ahead of print]

PMID:
31633866
2.

Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts.

Sunaga H, Koitabashi N, Iso T, Matsui H, Obokata M, Kawakami R, Murakami M, Yokoyama T, Kurabayashi M.

Sci Rep. 2019 Aug 14;9(1):11841. doi: 10.1038/s41598-019-48356-1.

3.

Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity.

Masubuchi H, Ueno M, Maeno T, Yamaguchi K, Hara K, Sunaga H, Matsui H, Nagasawa M, Kojima I, Iwata Y, Wakabayashi S, Kurabayashi M.

BMC Pulm Med. 2019 Mar 26;19(1):70. doi: 10.1186/s12890-019-0821-y.

4.

Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice.

Iso T, Haruyama H, Sunaga H, Matsui M, Matsui H, Tanaka R, Umbarawan Y, Syamsunarno MRAA, Yokoyama T, Kurabayashi M.

BMC Physiol. 2019 Mar 13;19(1):1. doi: 10.1186/s12899-019-0038-6.

5.

Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption.

Shrestha S, Sunaga H, Hanaoka H, Yamaguchi A, Kuwahara S, Umbarawan Y, Nakajima K, Machida T, Murakami M, Saito A, Tsushima Y, Kurabayashi M, Iso T.

Sci Rep. 2018 Nov 6;8(1):16451. doi: 10.1038/s41598-018-34902-w.

6.

CD36 is indispensable for nutrient homeostasis and endurance exercise capacity during prolonged fasting.

Iso T, Haruyama H, Sunaga H, Matsui H, Matsui M, Tanaka R, Umbarawan Y, Syamsunarno MRAA, Putri M, Yamaguchi A, Hanaoka H, Negishi K, Yokoyama T, Kurabayashi M.

Physiol Rep. 2018 Sep;6(19):e13884. doi: 10.14814/phy2.13884.

7.

Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine.

Savarese JJ, Sunaga H, McGilvra JD, Belmont MR, Murrell MT, Jeannotte E, Cooke FE, Wastila WB, Heerdt PM.

Anesthesiology. 2018 Nov;129(5):970-988. doi: 10.1097/ALN.0000000000002408.

PMID:
30212413
8.

Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure.

Umbarawan Y, Syamsunarno MRAA, Koitabashi N, Obinata H, Yamaguchi A, Hanaoka H, Hishiki T, Hayakawa N, Sano M, Sunaga H, Matsui H, Tsushima Y, Suematsu M, Kurabayashi M, Iso T.

Sci Rep. 2018 Aug 13;8(1):12035. doi: 10.1038/s41598-018-30616-1.

9.

Shielding design of a target station and radiation dose level investigation of proton linac for a compact accelerator-driven neutron source applied at industrial sites.

Ma B, Otake Y, Wang S, Sunaga H, Yamagata Y, Taketani A, Hu H, Jia Q, Hu G, Bautista U.

Appl Radiat Isot. 2018 Jul;137:129-138. doi: 10.1016/j.apradiso.2018.03.015. Epub 2018 Mar 20.

PMID:
29621703
10.

Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice.

Umbarawan Y, Syamsunarno MRAA, Koitabashi N, Yamaguchi A, Hanaoka H, Hishiki T, Nagahata-Naito Y, Obinata H, Sano M, Sunaga H, Matsui H, Tsushima Y, Suematsu M, Kurabayashi M, Iso T.

Cardiovasc Res. 2018 Jul 1;114(8):1132-1144. doi: 10.1093/cvr/cvy063.

11.

Posterior Reversible Encephalopathy Syndrome after Lenvatinib Therapy in a Patient with Anaplastic Thyroid Carcinoma.

Osawa Y, Gozawa R, Koyama K, Nakayama T, Sagoh T, Sunaga H.

Intern Med. 2018 Apr 1;57(7):1015-1019. doi: 10.2169/internalmedicine.9593-17. Epub 2017 Dec 8.

12.

Incidence of Anaphylaxis Associated With Sugammadex.

Miyazaki Y, Sunaga H, Kida K, Hobo S, Inoue N, Muto M, Uezono S.

Anesth Analg. 2018 May;126(5):1505-1508. doi: 10.1213/ANE.0000000000002562.

PMID:
29064876
13.

Association Between Circulating Ketone Bodies and Worse Outcomes in Hemodialysis Patients.

Obokata M, Negishi K, Sunaga H, Ishida H, Ito K, Ogawa T, Iso T, Ando Y, Kurabayashi M.

J Am Heart Assoc. 2017 Oct 3;6(10). pii: e006885. doi: 10.1161/JAHA.117.006885.

14.

Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice.

Umbarawan Y, Syamsunarno MRAA, Obinata H, Yamaguchi A, Sunaga H, Matsui H, Hishiki T, Matsuura T, Koitabashi N, Obokata M, Hanaoka H, Haque A, Kunimoto F, Tsushima Y, Suematsu M, Kurabayashi M, Iso T.

Metabolism. 2017 Dec;77:47-57. doi: 10.1016/j.metabol.2017.09.003. Epub 2017 Sep 20.

15.

Serum levels of fatty acid binding protein 4 and fat metabolic markers in relation to catecholamines following exercise.

Iso T, Sunaga H, Matsui H, Kasama S, Oshima N, Haruyama H, Furukawa N, Nakajima K, Machida T, Murakami M, Yokoyama T, Kurabayashi M.

Clin Biochem. 2017 Nov;50(16-17):896-902. doi: 10.1016/j.clinbiochem.2017.05.021. Epub 2017 Jun 2.

16.

Early increase in serum fatty acid binding protein 4 levels in patients with acute myocardial infarction.

Obokata M, Iso T, Ohyama Y, Sunaga H, Kawaguchi T, Matsui H, Iizuka T, Fukuda N, Takamatsu H, Koitabashi N, Funada R, Takama N, Kasama S, Kaneko Y, Yokoyama T, Murakami M, Kurabayashi M.

Eur Heart J Acute Cardiovasc Care. 2018 Sep;7(6):561-569. doi: 10.1177/2048872616683635. Epub 2016 Dec 22.

PMID:
30178960
17.

Anesthesia for nonintubated video-assisted thoracic surgery.

Sunaga H, Blasberg JD, Heerdt PM.

Curr Opin Anaesthesiol. 2017 Feb;30(1):1-6. doi: 10.1097/ACO.0000000000000413. Review.

PMID:
27906718
18.

Elongation of Long-Chain Fatty Acid Family Member 6 (Elovl6)-Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP-Activated Protein Kinase/Krüppel-Like Factor 4 (AMPK/KLF4) Signaling.

Sunaga H, Matsui H, Anjo S, Syamsunarno MR, Koitabashi N, Iso T, Matsuzaka T, Shimano H, Yokoyama T, Kurabayashi M.

J Am Heart Assoc. 2016 Nov 23;5(12). pii: e004014.

19.

Dose-response and Cardiopulmonary Side Effects of the Novel Neuromuscular-blocking Drug CW002 in Man.

Heerdt PM, Sunaga H, Owen JS, Murrell MT, Malhotra JK, Godfrey D, Steinkamp M, Savard P, Savarese JJ, Lien CA.

Anesthesiology. 2016 Dec;125(6):1136-1143.

PMID:
27749289
20.

Fibroblast growth factor 23 inhibits osteoblastic gene expression and induces osteoprotegerin in vascular smooth muscle cells.

Nakahara T, Kawai-Kowase K, Matsui H, Sunaga H, Utsugi T, Iso T, Arai M, Tomono S, Kurabayashi M.

Atherosclerosis. 2016 Oct;253:102-110. doi: 10.1016/j.atherosclerosis.2016.08.010. Epub 2016 Aug 20.

PMID:
27599364
21.

Independent and incremental prognostic value of novel cardiac biomarkers in chronic hemodialysis patients.

Obokata M, Sunaga H, Ishida H, Ito K, Ogawa T, Ando Y, Kurabayashi M, Negishi K.

Am Heart J. 2016 Sep;179:29-41. doi: 10.1016/j.ahj.2016.05.018. Epub 2016 Jun 18.

PMID:
27595677
22.

Preclinical Pharmacology of CW002: A Nondepolarizing Neuromuscular Blocking Drug of Intermediate Duration, Degraded and Antagonized by l-cysteine-Additional Studies of Safety and Efficacy in the Anesthetized Rhesus Monkey and Cat.

Sunaga H, Savarese JJ, McGilvra JD, Heerdt PM, Belmont MR, Van Ornum SG, Murrell MT, Malhotra JK, Savard PM, Jeannotte E, Petty BJ, Allen E, Carnathan GW.

Anesthesiology. 2016 Oct;125(4):732-743.

PMID:
27466033
23.

Pancuronium enhances isoflurane anesthesia in rats via inhibition of cerebral nicotinic acetylcholine receptors.

Miyazaki Y, Sunaga H, Hobo S, Miyano K, Uezono S.

J Anesth. 2016 Aug;30(4):671-6. doi: 10.1007/s00540-016-2178-1. Epub 2016 May 4.

PMID:
27146658
24.

Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression.

Wada T, Sunaga H, Miyata K, Shirasaki H, Uchiyama Y, Shimba S.

J Biol Chem. 2016 Mar 25;291(13):7004-16. doi: 10.1074/jbc.M115.693655. Epub 2016 Feb 10.

25.

Novel neuromuscular blocking drugs and antagonists.

Heerdt PM, Sunaga H, Savarese JJ.

Curr Opin Anaesthesiol. 2015 Aug;28(4):403-10. doi: 10.1097/ACO.0000000000000209. Review.

PMID:
26087274
26.

CD36 is indispensable for thermogenesis under conditions of fasting and cold stress.

Putri M, Syamsunarno MR, Iso T, Yamaguchi A, Hanaoka H, Sunaga H, Koitabashi N, Matsui H, Yamazaki C, Kameo S, Tsushima Y, Yokoyama T, Koyama H, Abumrad NA, Kurabayashi M.

Biochem Biophys Res Commun. 2015 Feb 20;457(4):520-5. doi: 10.1016/j.bbrc.2014.12.124. Epub 2015 Jan 13.

27.

Fatty acid binding protein 4 and 5 play a crucial role in thermogenesis under the conditions of fasting and cold stress.

Syamsunarno MR, Iso T, Yamaguchi A, Hanaoka H, Putri M, Obokata M, Sunaga H, Koitabashi N, Matsui H, Maeda K, Endo K, Tsushima Y, Yokoyama T, Kurabayashi M.

PLoS One. 2014 Mar 6;9(6):e90825. doi: 10.1371/journal.pone.0090825. eCollection 2014.

28.

SLURP-1, an endogenous α7 nicotinic acetylcholine receptor allosteric ligand, is expressed in CD205(+) dendritic cells in human tonsils and potentiates lymphocytic cholinergic activity.

Fujii T, Horiguchi K, Sunaga H, Moriwaki Y, Misawa H, Kasahara T, Tsuji S, Kawashima K.

J Neuroimmunol. 2014 Feb 15;267(1-2):43-9. doi: 10.1016/j.jneuroim.2013.12.003. Epub 2013 Dec 11.

PMID:
24365495
29.

Deranged fatty acid composition causes pulmonary fibrosis in Elovl6-deficient mice.

Sunaga H, Matsui H, Ueno M, Maeno T, Iso T, Syamsunarno MR, Anjo S, Matsuzaka T, Shimano H, Yokoyama T, Kurabayashi M.

Nat Commun. 2013;4:2563. doi: 10.1038/ncomms3563. Erratum in: Nat Commun. 2013;4:2937.

PMID:
24113622
30.

Regulation of the angiogenesis of acquired middle ear cholesteatomas by inhibitor of DNA binding transcription factor.

Fukudome S, Wang C, Hamajima Y, Ye S, Zheng Y, Narita N, Sunaga H, Fujieda S, Hu X, Feng L, Lin J.

JAMA Otolaryngol Head Neck Surg. 2013 Mar;139(3):273-8. doi: 10.1001/jamaoto.2013.1750.

PMID:
23657791
31.

Long-term compliance with nasal continuous positive airway pressure therapy for sleep apnea syndrome in an otorhinolaryngological office.

Tokunaga T, Ninomiya T, Kato Y, Ito Y, Takabayashi T, Tokuriki M, Sunaga H, Fujieda S.

Eur Arch Otorhinolaryngol. 2013 Aug;270(8):2267-73. doi: 10.1007/s00405-013-2483-3. Epub 2013 Apr 9.

PMID:
23568045
32.

Aryl hydrocarbon receptor modulates NADPH oxidase activity via direct transcriptional regulation of p40phox expression.

Wada T, Sunaga H, Ohkawara R, Shimba S.

Mol Pharmacol. 2013 May;83(5):1133-40. doi: 10.1124/mol.112.083303. Epub 2013 Mar 11.

PMID:
23478803
33.

Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes.

Matsui H, Yokoyama T, Tanaka C, Sunaga H, Koitabashi N, Takizawa T, Arai M, Kurabayashi M.

BMC Cell Biol. 2012 Dec 27;13:37. doi: 10.1186/1471-2121-13-37.

34.

Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes.

Matsui H, Yokoyama T, Sekiguchi K, Iijima D, Sunaga H, Maniwa M, Ueno M, Iso T, Arai M, Kurabayashi M.

PLoS One. 2012;7(3):e33283. doi: 10.1371/journal.pone.0033283. Epub 2012 Mar 8.

35.

A case of sinonasal teratocarcinosarcoma treated with surgery and post-operative intensity-modulated radiotherapy (IMRT).

Tokunaga T, Sunaga H, Kimura Y, Tsuda G, Fujieda S.

Auris Nasus Larynx. 2012 Dec;39(6):641-5. doi: 10.1016/j.anl.2012.01.010. Epub 2012 Feb 22.

PMID:
22361412
36.

B type CpG-DNA suppresses poly(I:C)-induced BLyS expression and production in human tonsillar fibroblasts.

Yamada T, Jiang X, Kubo S, Sakashita M, Narita N, Yamamoto H, Sunaga H, Fujieda S.

Clin Immunol. 2011 Dec;141(3):365-71. doi: 10.1016/j.clim.2011.09.012. Epub 2011 Sep 29.

PMID:
22015147
37.

Platelet derived endothelial cell growth factor/thymidine phosphorylase enhanced human IgE production.

Yamamoto H, Yamada T, Takabayashi T, Sunaga H, Oh M, Narita N, Kojima A, Fujieda S.

Allergol Int. 2011 Mar;60(1):79-85. doi: 10.2332/allergolint.10-OA-0220. Epub 2011 Jan 25.

38.

Cough reflex induced by capsaicin inhalation in patients with dysphagia.

Imoto Y, Kojima A, Osawa Y, Sunaga H, Fujieda S.

Acta Otolaryngol. 2011 Jan;131(1):96-100. doi: 10.3109/00016489.2010.516013. Epub 2010 Oct 29.

PMID:
21034170
39.

Rapid chemical antagonism of neuromuscular blockade by L-cysteine adduction to and inactivation of the olefinic (double-bonded) isoquinolinium diester compounds gantacurium (AV430A), CW 002, and CW 011.

Savarese JJ, McGilvra JD, Sunaga H, Belmont MR, Van Ornum SG, Savard PM, Heerdt PM.

Anesthesiology. 2010 Jul;113(1):58-73. doi: 10.1097/ALN.0b013e3181dc1b5b.

PMID:
20526187
40.

Pharmacodynamics and cardiopulmonary side effects of CW002, a cysteine-reversible neuromuscular blocking drug in dogs.

Heerdt PM, Malhotra JK, Pan BY, Sunaga H, Savarese JJ.

Anesthesiology. 2010 Apr;112(4):910-6. doi: 10.1097/ALN.0b013e3181d31f71.

PMID:
20234311
41.

Cysteine reversal of the novel neuromuscular blocking drug CW002 in dogs: pharmacodynamics, acute cardiovascular effects, and preliminary toxicology.

Sunaga H, Malhotra JK, Yoon E, Savarese JJ, Heerdt PM.

Anesthesiology. 2010 Apr;112(4):900-9. doi: 10.1097/ALN.0b013e3181d31f8c.

PMID:
20234310
42.

Gantacurium and CW002 do not potentiate muscarinic receptor-mediated airway smooth muscle constriction in guinea pigs.

Sunaga H, Zhang Y, Savarese JJ, Emala CW.

Anesthesiology. 2010 Apr;112(4):892-9. doi: 10.1097/ALN.0b013e3181d32016.

43.

Fumarates: unique nondepolarizing neuromuscular blocking agents that are antagonized by cysteine.

Lien CA, Savard P, Belmont M, Sunaga H, Savarese JJ.

J Crit Care. 2009 Mar;24(1):50-7. doi: 10.1016/j.jcrc.2008.11.001. Review. No abstract available.

PMID:
19272539
44.

Expression of Syk is associated with nasal polyp in patients with allergic rhinitis.

Hamajima Y, Fujieda S, Sunaga H, Yamada T, Moribe K, Watanabe N, Murakami S.

Auris Nasus Larynx. 2007 Mar;34(1):49-56. Epub 2006 Dec 1.

PMID:
17141440
45.
46.

Reliability of platelet-derived endothelial cell growth factor as a prognostic factor for oral and oropharyngeal carcinomas.

Tsuzuki H, Sunaga H, Ito T, Narita N, Sugimoto C, Fujieda S.

Arch Otolaryngol Head Neck Surg. 2005 Dec;131(12):1071-8.

PMID:
16365220
47.

Oral and oropharyngeal squamous cell carcinomas expressing CCR7 have poor prognoses.

Tsuzuki H, Takahashi N, Kojima A, Narita N, Sunaga H, Takabayashi T, Fujieda S.

Auris Nasus Larynx. 2006 Mar;33(1):37-42. Epub 2005 Oct 11.

PMID:
16223574
48.

Infection of Haemophilus parainfluenzae in tonsils is associated with IgA nephropathy.

Sunaga H, Oh M, Takahashi N, Fujieda S.

Acta Otolaryngol Suppl. 2004 Dec;(555):15-9.

PMID:
15768791
49.

Combined treatment of cisplatin and overexpression of caspase-activated deoxyribonuclease (CAD) promotes apoptosis in vitro and in vivo.

Kimura Y, Sugimoto C, Matsukawa S, Sunaga H, Igawa H, Yamamoto H, Ito T, Saito H, Fujieda S.

Oral Oncol. 2004 Apr;40(4):390-9.

PMID:
14969818
50.

Expression of p27 and apoptosis in oral leukoplakia.

Tsuzuki H, Fujieda S, Sunaga H, Narita N, Tokuriki M, Saito H.

Anticancer Res. 2003 Mar-Apr;23(2B):1265-70.

PMID:
12820381

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