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Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors.

Hsueh YS, Chang HH, Shan YS, Sun HS, Fletcher JA, Li CF, Chen LT.

Oncogene. 2019 Jul 30. doi: 10.1038/s41388-019-0900-9. [Epub ahead of print]


Neuroprotective Effects of AG490 in Neonatal Hypoxic-Ischemic Brain Injury.

Li F, Wong R, Luo Z, Du L, Turlova E, Britto LRG, Feng ZP, Sun HS.

Mol Neurobiol. 2019 Jun 12. doi: 10.1007/s12035-019-01656-z. [Epub ahead of print]


Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice.

Ma MM, Jin CC, Huang XL, Sun L, Zhou H, Wen XJ, Huang XQ, Du JY, Sun HS, Ren ZX, Liu J, Guan YY, Zhao XM, Wang GL.

Acta Pharmacol Sin. 2019 Jun 5. doi: 10.1038/s41401-019-0229-5. [Epub ahead of print]


Role of Cl- channels in primary brain tumour.

Saberbaghi T, Wong R, Rutka JT, Wang GL, Feng ZP, Sun HS.

Cell Calcium. 2019 Jul;81:1-11. doi: 10.1016/j.ceca.2019.05.004. Epub 2019 May 14. Review.


Fibroblast growth factors: Potential novel targets for regenerative therapy of osteoarthritis.

Chen TM, Chen YH, Sun HS, Tsai SJ.

Chin J Physiol. 2019 Jan-Feb;62(1):2-10. doi: 10.4103/CJP.CJP_11_19. Review.


hnRNPM induces translation switch under hypoxia to promote colon cancer development.

Chen TM, Lai MC, Li YH, Chan YL, Wu CH, Wang YM, Chien CW, Huang SY, Sun HS, Tsai SJ.

EBioMedicine. 2019 Mar;41:299-309. doi: 10.1016/j.ebiom.2019.02.059. Epub 2019 Mar 7.


Numerical investigation of the influence of a bearing/shaft structure in an axial blood pump on the potential for device thrombosis.

Liu GM, Jin DH, Chen HB, Hou JF, Zhang Y, Sun HS, Zhou JY, Hu SS, Gui XM.

Int J Artif Organs. 2019 Apr;42(4):182-189. doi: 10.1177/0391398818823769. Epub 2019 Jan 10.


Marine Compound Xyloketal B as a Potential Drug Development Target for Neuroprotection.

Gong H, Luo Z, Chen W, Feng ZP, Wang GL, Sun HS.

Mar Drugs. 2018 Dec 19;16(12). pii: E516. doi: 10.3390/md16120516. Review.


Fibroblast growth factor 9 activates anti-oxidative functions of Nrf2 through ERK signalling in striatal cell models of Huntington's disease.

Yusuf IO, Chen HM, Cheng PH, Chang CY, Tsai SJ, Chuang JI, Wu CC, Huang BM, Sun HS, Yang SH.

Free Radic Biol Med. 2019 Jan;130:256-266. doi: 10.1016/j.freeradbiomed.2018.10.455. Epub 2018 Nov 2.


CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses.

Liu DD, Yuan X, Chu SF, Chen C, Ren Q, Luo P, Lin MY, Wang SS, Zhu TB, Ai QD, Zang YD, Zhang DM, He X, Huang ZH, Sun HS, Feng ZP, Chen NH.

Acta Pharmacol Sin. 2019 Apr;40(4):425-440. doi: 10.1038/s41401-018-0078-7. Epub 2018 Oct 31.


Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway.

Chu SF, Zhang Z, Zhou X, He WB, Chen C, Luo P, Liu DD, Ai QD, Gong HF, Wang ZZ, Sun HS, Feng ZP, Chen NH.

Acta Pharmacol Sin. 2019 Jan;40(1):13-25. doi: 10.1038/s41401-018-0154-z. Epub 2018 Sep 27.


Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus.

Ma ZZ, Sun HS, Lv JC, Guo L, Yang QR.

J Inflamm (Lond). 2018 Sep 3;15:16. doi: 10.1186/s12950-018-0192-9. eCollection 2018.


FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells.

Chang MM, Lai MS, Hong SY, Pan BS, Huang H, Yang SH, Wu CC, Sun HS, Chuang JI, Wang CY, Huang BM.

Cancer Sci. 2018 Nov;109(11):3503-3518. doi: 10.1111/cas.13793. Epub 2018 Oct 23.


Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models.

Deurloo MHS, Turlova E, Chen WL, Lin YW, Tam E, Tassew NG, Wu M, Huang YC, Crawley JN, Monnier PP, Groffen AJA, Sun HS, Osborne LR, Feng ZP.

Mol Neurobiol. 2019 May;56(5):3313-3325. doi: 10.1007/s12035-018-1290-7. Epub 2018 Aug 17.


Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington's Disease.

Yusuf IO, Cheng PH, Chen HM, Chang YF, Chang CY, Yang HI, Lin CW, Tsai SJ, Chuang JI, Wu CC, Huang BM, Sun HS, Yang SH.

Cell Physiol Biochem. 2018;48(2):605-617. doi: 10.1159/000491889. Epub 2018 Jul 18.


Effects of SLCO1B1 and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high plasma exposure of rosuvastatin and its metabolites.

Bai X, Zhang B, Wang P, Wang GL, Li JL, Wen DS, Long XZ, Sun HS, Liu YB, Huang M, Zhong SL.

Acta Pharmacol Sin. 2019 Apr;40(4):492-499. doi: 10.1038/s41401-018-0013-y. Epub 2018 Jun 27.


Surgical Treatment of Left Ventricular Pseudoaneurysm.

Zhang Y, Yang Y, Sun HS, Tang Y.

Chin Med J (Engl). 2018 Jun 20;131(12):1496-1497. doi: 10.4103/0366-6999.233954. No abstract available.


C2 Domains of Munc13-4 Are Crucial for Ca2+-Dependent Degranulation and Cytotoxicity in NK Cells.

Bin NR, Ma K, Tien CW, Wang S, Zhu D, Park S, Turlova E, Sugita K, Shirakawa R, van der Sluijs P, Horiuchi H, Sun HS, Monnier PP, Gaisano HY, Sugita S.

J Immunol. 2018 Jul 15;201(2):700-713. doi: 10.4049/jimmunol.1800426. Epub 2018 Jun 8.


The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells.

Joseph NA, Chiou SH, Lung Z, Yang CL, Lin TY, Chang HW, Sun HS, Gupta SK, Yen L, Wang SD, Chow KC.

J Hematol Oncol. 2018 May 31;11(1):74. doi: 10.1186/s13045-018-0557-9.


Disease-association of different killer cell immunoglobulin-like receptors (KIR) and HLA-C gene combinations in reactive arthritis.

Sun HS, Liu DX, Bai YY, Hu NW.

Mod Rheumatol. 2019 May;29(3):531-537. doi: 10.1080/14397595.2018.1483292. Epub 2018 Jul 23.


A new platform for international collaboration on pharmacology and drug development: 2017 China-Canada-USA Pharmacology/Physiology Conference.

Feng ZP, Sun HS.

Acta Pharmacol Sin. 2018 May;39(5):659-660. doi: 10.1038/aps.2018.34. No abstract available.


Mitochondrial Autophagy and NLRP3 Inflammasome in Pulmonary Tissues from Severe Combined Immunodeficient Mice after Cardiac Arrest and Cardiopulmonary Resuscitation.

Lyu JJ, Mehta JL, Li Y, Ye L, Sun SN, Sun HS, Li JC, Zhang DM, Wei J.

Chin Med J (Engl). 2018 May 20;131(10):1174-1184. doi: 10.4103/0366-6999.231519.


Outcomes of Ebstein's Anomaly Patients Treated with Tricuspid Valvuloplasty or Tricuspid Valve Replacement: Experience of a Single Center.

Li B, Sun HS, Pan SW, Xu JP.

Chin Med J (Engl). 2018 May 5;131(9):1067-1074. doi: 10.4103/0366-6999.230731.


The role of KATP channels in cerebral ischemic stroke and diabetes.

Szeto V, Chen NH, Sun HS, Feng ZP.

Acta Pharmacol Sin. 2018 May;39(5):683-694. doi: 10.1038/aps.2018.10. Epub 2018 Apr 19. Review.


Pharmacological approaches promoting stem cell-based therapy following ischemic stroke insults.

Zhu SZ, Szeto V, Bao MH, Sun HS, Feng ZP.

Acta Pharmacol Sin. 2018 May;39(5):695-712. doi: 10.1038/aps.2018.23. Epub 2018 Apr 19. Review.


Xyloketal B exerts antihypertensive effect in renovascular hypertensive rats via the NO-sGC-cGMP pathway and calcium signaling.

Zhao LY, Li J, Huang XQ, Wang GH, Lv XF, Meng WF, Chen WL, Pang JY, Lin YC, Sun HS, Wang GL, Du YM.

Acta Pharmacol Sin. 2018 May;39(5):875-884. doi: 10.1038/aps.2018.12. Epub 2018 Mar 29.


Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo.

Wong R, Abussaud A, Leung JW, Xu BF, Li FY, Huang S, Chen NH, Wang GL, Feng ZP, Sun HS.

Acta Pharmacol Sin. 2018 May;39(5):858-865. doi: 10.1038/aps.2018.1. Epub 2018 Mar 29.


Dopamine-mediated calcium channel regulation in synaptic suppression in L. stagnalis interneurons.

Dong N, Lee DWK, Sun HS, Feng ZP.

Channels (Austin). 2018 Jan 1;12(1):153-173. doi: 10.1080/19336950.2018.1457897.


Combined measurement of plasma cystatin C and low-density lipoprotein cholesterol: A valuable tool for evaluating progressive supranuclear palsy.

Weng R, Wei X, Yu B, Zhu S, Yang X, Xie F, Zhang M, Jiang Y, Feng ZP, Sun HS, Xia Y, Jin K, Chan P, Wang Q, Gao X.

Parkinsonism Relat Disord. 2018 Jul;52:37-42. doi: 10.1016/j.parkreldis.2018.03.014. Epub 2018 Mar 19.


NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation.

Lin YJ, Hsin IL, Sun HS, Lin S, Lai YL, Chen HY, Chen TY, Chen YP, Shen YT, Wu HM.

Mol Neurobiol. 2018 Nov;55(11):8403-8413. doi: 10.1007/s12035-018-0995-y. Epub 2018 Mar 16.


The role of TRPM2 channels in neurons, glial cells and the blood-brain barrier in cerebral ischemia and hypoxia.

Turlova E, Feng ZP, Sun HS.

Acta Pharmacol Sin. 2018 May;39(5):713-721. doi: 10.1038/aps.2017.194. Epub 2018 Mar 15. Review.


MiR-378 promotes the cell proliferation of non-small cell lung cancer by inhibiting FOXG1.

Ji KX, Cui F, Qu D, Sun RY, Sun P, Chen FY, Wang SL, Sun HS.

Eur Rev Med Pharmacol Sci. 2018 Feb;22(4):1011-1019. doi: 10.26355/eurrev_201802_14383.


Long non-coding RNAs in ischemic stroke.

Bao MH, Szeto V, Yang BB, Zhu SZ, Sun HS, Feng ZP.

Cell Death Dis. 2018 Feb 15;9(3):281. doi: 10.1038/s41419-018-0282-x. Review.


Meta-Analysis on the Association between Brain-Derived Neurotrophic Factor Polymorphism rs6265 and Ischemic Stroke, Poststroke Depression.

Bao MH, Zhu SZ, Gao XZ, Sun HS, Feng ZP.

J Stroke Cerebrovasc Dis. 2018 Jun;27(6):1599-1608. doi: 10.1016/j.jstrokecerebrovasdis.2018.01.010. Epub 2018 Feb 13. Review.


Dietary Curcumin Intervention Targets Mouse White Adipose Tissue Inflammation and Brown Adipose Tissue UCP1 Expression.

Song Z, Revelo X, Shao W, Tian L, Zeng K, Lei H, Sun HS, Woo M, Winer D, Jin T.

Obesity (Silver Spring). 2018 Mar;26(3):547-558. doi: 10.1002/oby.22110. Epub 2018 Feb 6.


Inhibition of CREPT restrains gastric cancer growth by regulation of cycle arrest, migration and apoptosis via ROS-regulated p53 pathway.

Sun M, Si G, Sun HS, Si FC.

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1183-1190. doi: 10.1016/j.bbrc.2018.01.167. Epub 2018 Jan 31.


Numerical Investigation of the Influence of Blade Radial Gap Flow on Axial Blood Pump Performance.

Liu GM, Jin DH, Zhou JY, Zhang Y, Chen HB, Sun HS, Hu SS, Gui XM.

ASAIO J. 2019 Jan;65(1):59-69. doi: 10.1097/MAT.0000000000000745.


Crystal structure of diethyl 3,3'-[(4-nitro-phen-yl)methyl-ene]bis-(1H-indole-2-carboxyl-ate).

Sun HS, Li YL, Jiang H, Chen YL, Hu YD.

Acta Crystallogr E Crystallogr Commun. 2017 Nov 28;73(Pt 12):1956-1958. doi: 10.1107/S2056989017016929. eCollection 2017 Dec 1.


Crystal structure of diethyl 3,3'-[(2,4-di-chloro-phen-yl)methyl-idene]bis-(1H-indole-2-carboxyl-ate).

Li YL, Sun HS, Jiang H, Chen YL, Chen YF.

Acta Crystallogr E Crystallogr Commun. 2017 Nov 3;73(Pt 12):1817-1819. doi: 10.1107/S2056989017015730. eCollection 2017 Dec 1.


Validation of simplified postoperative nausea and vomiting intensity scale in Taiwan.

Shin HC, Kang TW, Wu YH, Sun HS, Tseng CA.

J Clin Monit Comput. 2018 Oct;32(5):937-944. doi: 10.1007/s10877-017-0084-1. Epub 2017 Dec 1.


Crystal structure of diethyl 3,3'-[(2-fluoro-phen-yl)methyl-idene]bis-(1H-indole-2-carboxyl-ate).

Lu XH, Sun HS, Cai Y, Chen LL, Chen YF.

Acta Crystallogr E Crystallogr Commun. 2017 Oct 31;73(Pt 11):1790-1792. doi: 10.1107/S2056989017015523. eCollection 2017 Nov 1.


UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans.

Park S, Bin NR, Yu B, Wong R, Sitarska E, Sugita K, Ma K, Xu J, Tien CW, Algouneh A, Turlova E, Wang S, Siriya P, Shahid W, Kalia L, Feng ZP, Monnier PP, Sun HS, Zhen M, Gao S, Rizo J, Sugita S.

J Neurosci. 2017 Sep 6;37(36):8797-8815. doi: 10.1523/JNEUROSCI.0338-17.2017. Epub 2017 Aug 8.


Design and numerical evaluation of an axial partial-assist blood pump for Chinese and other heart failure patients.

Liu GM, Jin DH, Zhou JY, Jiang XH, Sun HS, Zhang Y, Chen HB, Hu SS, Gui XM.

Int J Artif Organs. 2017 Sep 15;40(9):489-497. doi: 10.5301/ijao.5000616. Epub 2017 Aug 2.


Transient receptor potential melastatin 2 channels (TRPM2) mediate neonatal hypoxic-ischemic brain injury in mice.

Huang S, Turlova E, Li F, Bao MH, Szeto V, Wong R, Abussaud A, Wang H, Zhu S, Gao X, Mori Y, Feng ZP, Sun HS.

Exp Neurol. 2017 Oct;296:32-40. doi: 10.1016/j.expneurol.2017.06.023. Epub 2017 Jun 29.


Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness.

Hou PC, Li YH, Lin SC, Lin SC, Lee JC, Lin BW, Liou JP, Chang JY, Kuo CC, Liu YM, Sun HS, Tsai SJ.

Cancer Res. 2017 Aug 15;77(16):4305-4316. doi: 10.1158/0008-5472.CAN-16-2990. Epub 2017 Jun 26.


Xyloketal B alleviates cerebral infarction and neurologic deficits in a mouse stroke model by suppressing the ROS/TLR4/NF-κB inflammatory signaling pathway.

Pan N, Lu LY, Li M, Wang GH, Sun FY, Sun HS, Wen XJ, Cheng JD, Chen JW, Pang JY, Liu J, Guan YY, Zhao LY, Chen WL, Wang GL.

Acta Pharmacol Sin. 2017 Sep;38(9):1236-1247. doi: 10.1038/aps.2017.22. Epub 2017 May 29.


Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model.

Dati LM, Ulrich H, Real CC, Feng ZP, Sun HS, Britto LR.

Neuroscience. 2017 Jul 25;356:176-181. doi: 10.1016/j.neuroscience.2017.05.013. Epub 2017 May 17.


Circular RNA - New member of noncoding RNA with novel functions.

Hsiao KY, Sun HS, Tsai SJ.

Exp Biol Med (Maywood). 2017 Jun;242(11):1136-1141. doi: 10.1177/1535370217708978. Epub 2017 May 9. Review.


[Research progress of serum proteomics in the diagnosis of tuberculosis].

Sun HS, Pan LP, Jia HY.

Zhonghua Jie He He Hu Xi Za Zhi. 2017 May 12;40(5):363-365. doi: 10.3760/cma.j.issn.1001-0939.2017.05.010. Chinese. No abstract available.


[Water Quality Analysis of Beijing Segment of South-to-North Water Diversion Middle Route Project].

Xu HS, Zhao L, Sun HS, Ren YF, Ding T, Chang S, Wang HD, Li M, Guo Z.

Huan Jing Ke Xue. 2017 Apr 8;38(4):1357-1365. doi: 10.13227/j.hjkx.201607068. Chinese.


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