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Items: 29


Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units.

Giorgetti E, Panesar M, Zhang Y, Joller S, Ronco M, Obrecht M, Lambert C, Accart N, Beckmann N, Doelemeyer A, Perrot L, Fruh I, Mueller M, Pierrel E, Summermatter S, Bidinosti M, Shimshek DR, Brachat S, Nash M.

Cell Rep. 2019 Nov 5;29(6):1539-1554.e7. doi: 10.1016/j.celrep.2019.10.003.


HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70.

Luo L, Martin SC, Parkington J, Cadena SM, Zhu J, Ibebunjo C, Summermatter S, Londraville N, Patora-Komisarska K, Widler L, Zhai H, Trendelenburg AU, Glass DJ, Shi J.

Cell Rep. 2019 Oct 15;29(3):749-763.e12. doi: 10.1016/j.celrep.2019.09.023.


Mouse models of cancer-induced cachexia: Hind limb muscle mass and evoked force as readouts.

Jourdain M, Melly S, Summermatter S, Hatakeyama S.

Biochem Biophys Res Commun. 2018 Sep 18;503(4):2415-2420. doi: 10.1016/j.bbrc.2018.06.170. Epub 2018 Jul 6.


Relation of nNOS isoforms to mitochondrial density and PGC-1alpha expression in striated muscles of mice.

Baum O, Aaldijk D, Engeli AL, Spree M, Summermatter S, Handschin C, Zakrzewicz A.

Nitric Oxide. 2018 Jul 1;77:35-43. doi: 10.1016/j.niox.2018.04.005. Epub 2018 Apr 17.


Respiratory muscle training improves respiratory muscle endurance but not exercise tolerance in children with cystic fibrosis.

Bieli C, Summermatter S, Boutellier U, Moeller A.

Pediatr Pulmonol. 2017 Mar;52(3):331-336. doi: 10.1002/ppul.23647. Epub 2017 Jan 23.


Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength.

Summermatter S, Bouzan A, Pierrel E, Melly S, Stauffer D, Gutzwiller S, Nolin E, Dornelas C, Fryer C, Leighton-Davies J, Glass DJ, Fournier B.

Mol Cell Biol. 2017 Feb 15;37(5). pii: e00305-16. doi: 10.1128/MCB.00305-16. Print 2017 Mar 1.


Feasibility of nitrogen multiple-breath washout in inexperienced children younger than 7 years.

Yammine S, Summermatter S, Singer F, Lauener R, Latzin P.

Pediatr Pulmonol. 2016 Nov;51(11):1183-1190. doi: 10.1002/ppul.23431. Epub 2016 May 1.


ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments.

Hatakeyama S, Summermatter S, Jourdain M, Melly S, Minetti GC, Lach-Trifilieff E.

Skelet Muscle. 2016 Jul 26;6:26. doi: 10.1186/s13395-016-0098-2. eCollection 2016.


Oral immunotherapy with low allergenic hydrolysed egg in egg allergic children.

Giavi S, Vissers YM, Muraro A, Lauener R, Konstantinopoulos AP, Mercenier A, Wermeille A, Lazzarotto F, Frei R, Bonaguro R, Summermatter S, Nutten S, Papadopoulos NG.

Allergy. 2016 Nov;71(11):1575-1584. doi: 10.1111/all.12905. Epub 2016 May 13.


Impact of Software Settings on Multiple-Breath Washout Outcomes.

Summermatter S, Singer F, Latzin P, Yammine S.

PLoS One. 2015 Jul 13;10(7):e0132250. doi: 10.1371/journal.pone.0132250. eCollection 2015.


The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling.

Pérez-Schindler J, Summermatter S, Santos G, Zorzato F, Handschin C.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20314-9. doi: 10.1073/pnas.1312039110. Epub 2013 Nov 25.


Compensation of signal loss due to cardiac motion in point-resolved spectroscopy of the heart.

Weiss K, Summermatter S, Stoeck CT, Kozerke S.

Magn Reson Med. 2014 Nov;72(5):1201-7. doi: 10.1002/mrm.25028. Epub 2013 Nov 20.


Skeletal muscle PGC-1α controls whole-body lactate homeostasis through estrogen-related receptor α-dependent activation of LDH B and repression of LDH A.

Summermatter S, Santos G, Pérez-Schindler J, Handschin C.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8738-43. doi: 10.1073/pnas.1212976110. Epub 2013 May 6.


Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.

Bentzinger CF, Lin S, Romanino K, Castets P, Guridi M, Summermatter S, Handschin C, Tintignac LA, Hall MN, Rüegg MA.

Skelet Muscle. 2013 Mar 6;3(1):6. doi: 10.1186/2044-5040-3-6.


PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner.

Summermatter S, Shui G, Maag D, Santos G, Wenk MR, Handschin C.

Diabetes. 2013 Jan;62(1):85-95. doi: 10.2337/db12-0291. Epub 2012 Oct 18.


The corepressor NCoR1 antagonizes PGC-1α and estrogen-related receptor α in the regulation of skeletal muscle function and oxidative metabolism.

Pérez-Schindler J, Summermatter S, Salatino S, Zorzato F, Beer M, Balwierz PJ, van Nimwegen E, Feige JN, Auwerx J, Handschin C.

Mol Cell Biol. 2012 Dec;32(24):4913-24. doi: 10.1128/MCB.00877-12. Epub 2012 Oct 1.


A role for adipose tissue de novo lipogenesis in glucose homeostasis during catch-up growth: a Randle cycle favoring fat storage.

Marcelino H, Veyrat-Durebex C, Summermatter S, Sarafian D, Miles-Chan J, Arsenijevic D, Zani F, Montani JP, Seydoux J, Solinas G, Rohner-Jeanrenaud F, Dulloo AG.

Diabetes. 2013 Feb;62(2):362-72. doi: 10.2337/db12-0255. Epub 2012 Sep 6.


PGC-1α and exercise in the control of body weight.

Summermatter S, Handschin C.

Int J Obes (Lond). 2012 Nov;36(11):1428-35. doi: 10.1038/ijo.2012.12. Epub 2012 Jan 31. Review.


Remodeling of calcium handling in skeletal muscle through PGC-1α: impact on force, fatigability, and fiber type.

Summermatter S, Thurnheer R, Santos G, Mosca B, Baum O, Treves S, Hoppeler H, Zorzato F, Handschin C.

Am J Physiol Cell Physiol. 2012 Jan 1;302(1):C88-99. doi: 10.1152/ajpcell.00190.2011. Epub 2011 Sep 14.


Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity.

Summermatter S, Troxler H, Santos G, Handschin C.

Biochem Biophys Res Commun. 2011 Apr 29;408(1):180-5. doi: 10.1016/j.bbrc.2011.04.012. Epub 2011 Apr 8.


Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.

Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C.

J Biol Chem. 2010 Oct 22;285(43):32793-800. doi: 10.1074/jbc.M110.145995. Epub 2010 Aug 17.


Electric pulse stimulation of cultured murine muscle cells reproduces gene expression changes of trained mouse muscle.

Burch N, Arnold AS, Item F, Summermatter S, Brochmann Santana Santos G, Christe M, Boutellier U, Toigo M, Handschin C.

PLoS One. 2010 Jun 4;5(6):e10970. doi: 10.1371/journal.pone.0010970.


For a pragmatic approach to exercise studies.

Handschin C, Summermatter S, LeBrasseur NK, Lin J, Spiegelman BM.

J Appl Physiol (1985). 2010 Jan;108(1):223-3; author reply 226. doi: 10.1152/japplphysiol.01233.2009. No abstract available.


Adipose tissue plasticity during catch-up fat driven by thrifty metabolism: relevance for muscle-adipose glucose redistribution during catch-up growth.

Summermatter S, Marcelino H, Arsenijevic D, Buchala A, Aprikian O, Assimacopoulos-Jeannet F, Seydoux J, Montani JP, Solinas G, Dulloo AG.

Diabetes. 2009 Oct;58(10):2228-37. doi: 10.2337/db08-1793. Epub 2009 Jul 14.


Thrifty metabolism that favors fat storage after caloric restriction: a role for skeletal muscle phosphatidylinositol-3-kinase activity and AMP-activated protein kinase.

Summermatter S, Mainieri D, Russell AP, Seydoux J, Montani JP, Buchala A, Solinas G, Dulloo AG.

FASEB J. 2008 Mar;22(3):774-85. Epub 2007 Oct 10.


A role for skeletal muscle stearoyl-CoA desaturase 1 in control of thermogenesis.

Mainieri D, Summermatter S, Seydoux J, Montani JP, Rusconi S, Russell AP, Boss O, Buchala AJ, Dulloo AG.

FASEB J. 2006 Aug;20(10):1751-3. Epub 2006 Jun 29.


Corticotropin-releasing hormone directly stimulates thermogenesis in skeletal muscle possibly through substrate cycling between de novo lipogenesis and lipid oxidation.

Solinas G, Summermatter S, Mainieri D, Gubler M, Montani JP, Seydoux J, Smith SR, Dulloo AG.

Endocrinology. 2006 Jan;147(1):31-8. Epub 2005 Oct 6.


Redistribution of glucose from skeletal muscle to adipose tissue during catch-up fat: a link between catch-up growth and later metabolic syndrome.

Cettour-Rose P, Samec S, Russell AP, Summermatter S, Mainieri D, Carrillo-Theander C, Montani JP, Seydoux J, Rohner-Jeanrenaud F, Dulloo AG.

Diabetes. 2005 Mar;54(3):751-6.


The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation.

Solinas G, Summermatter S, Mainieri D, Gubler M, Pirola L, Wymann MP, Rusconi S, Montani JP, Seydoux J, Dulloo AG.

FEBS Lett. 2004 Nov 19;577(3):539-44.

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