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Items: 1 to 50 of 96

1.

Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells.

Tajitsu Y, Ikeda R, Nishizawa Y, Mataki H, Che XF, Sumizawa T, Nitta M, Yamaguchi T, Yamamoto M, Tabata S, Akiyama S, Yamada K, Furukawa T, Takeda Y.

Int J Mol Med. 2013 Sep;32(3):703-8. doi: 10.3892/ijmm.2013.1428. Epub 2013 Jul 2.

PMID:
23820674
2.

Binding of titanium dioxide nanoparticles to lactate dehydrogenase.

Zaqout MS, Sumizawa T, Igisu H, Wilson D, Myojo T, Ueno S.

Environ Health Prev Med. 2012 Jul;17(4):341-5. doi: 10.1007/s12199-011-0245-7. Epub 2011 Oct 13.

3.

[Elucidation of the function based on the whole structure of rat liver vault, the largest ribonucleo-protein particle].

Tanaka H, Kato K, Sumizawa T, Yamashita E.

Seikagaku. 2011 May;83(5):392-5. Review. Japanese. No abstract available.

PMID:
21706874
4.

Binding of human serum proteins to titanium dioxide particles in vitro.

Zaqout MS, Sumizawa T, Igisu H, Higashi T, Myojo T.

J Occup Health. 2011;53(2):75-83. Epub 2011 Jan 17.

5.

p53 Plays an important role in cell fate determination after exposure to microcystin-LR.

Takumi S, Komatsu M, Furukawa T, Ikeda R, Sumizawa T, Akenaga H, Maeda Y, Aoyama K, Arizono K, Ando S, Takeuchi T.

Environ Health Perspect. 2010 Sep;118(9):1292-8. doi: 10.1289/ehp.1001899. Epub 2010 Apr 26.

6.

Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1alpha and reduces HIF-1alpha level in ACHN human renal adenocarcinoma cells.

Iwashita K, Ikeda R, Takeda Y, Sumizawa T, Furukawa T, Yamaguchi T, Akiyama S, Yamada K.

Cancer Sci. 2010 Apr;101(4):920-6. doi: 10.1111/j.1349-7006.2009.01481.x. Epub 2010 Feb 18.

7.

Characterization of organogel as a novel oral controlled release formulation for lipophilic compounds.

Iwanaga K, Sumizawa T, Miyazaki M, Kakemi M.

Int J Pharm. 2010 Mar 30;388(1-2):123-8. doi: 10.1016/j.ijpharm.2009.12.045. Epub 2010 Jan 4.

PMID:
20045041
8.

Suppression of acrylamide toxicity by carboxyfullerene in human neuroblastoma cells in vitro.

Sumizawa T, Igisu H.

Arch Toxicol. 2009 Sep;83(9):817-24. doi: 10.1007/s00204-009-0438-7. Epub 2009 May 28.

PMID:
19475399
9.

The structure of rat liver vault at 3.5 angstrom resolution.

Tanaka H, Kato K, Yamashita E, Sumizawa T, Zhou Y, Yao M, Iwasaki K, Yoshimura M, Tsukihara T.

Science. 2009 Jan 16;323(5912):384-8. doi: 10.1126/science.1164975.

10.

Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells.

Ikeda R, Iwashita K, Sumizawa T, Beppu S, Tabata S, Tajitsu Y, Shimamoto Y, Yoshida K, Furukawa T, Che XF, Yamaguchi T, Ushiyama M, Miyawaki A, Takeda Y, Yamamoto M, Zhao HY, Shibayama Y, Yamada K, Akiyama S.

Exp Cell Res. 2008 Oct 1;314(16):3017-26. doi: 10.1016/j.yexcr.2008.07.001. Epub 2008 Jul 9.

PMID:
18671966
11.

A vault ribonucleoprotein particle exhibiting 39-fold dihedral symmetry.

Kato K, Tanaka H, Sumizawa T, Yoshimura M, Yamashita E, Iwasaki K, Tsukihara T.

Acta Crystallogr D Biol Crystallogr. 2008 May;64(Pt 5):525-31. doi: 10.1107/S0907444908004277. Epub 2008 Apr 19. Erratum in: Acta Crystallogr D Biol Crystallogr. 2009 Mar;65(Pt 3):301.

12.
13.

Isolation and characterization of arsenite-resistant human epidermoid carcinoma KB cells.

Tachiwada T, Chen ZS, Che XF, Matsumoto M, Haraguchi M, Gotanda T, Sumizawa T, Furukawa T, Nishiyama K, Seki N, Yamamoto M, Nakagawa M, Akiyama S.

Oncol Rep. 2007 Sep;18(3):721-7.

PMID:
17671726
14.

Apoptosis induced by acrylamide in SH-SY5Y cells.

Sumizawa T, Igisu H.

Arch Toxicol. 2007 Apr;81(4):279-82. Epub 2006 Aug 25.

PMID:
16932918
15.

Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.

Gotanda T, Haraguchi M, Tachiwada T, Shinkura R, Koriyama C, Akiba S, Kawahara M, Nishiyama K, Sumizawa T, Furukawa T, Mimata H, Nomura Y, Akiyama S, Nakagawa M.

Int J Mol Med. 2006 Jun;17(6):1085-91.

PMID:
16685420
16.

2-Deoxy-D-ribose inhibits hypoxia-induced apoptosis by suppressing the phosphorylation of p38 MAPK.

Ikeda R, Che XF, Ushiyama M, Yamaguchi T, Okumura H, Nakajima Y, Takeda Y, Shibayama Y, Furukawa T, Yamamoto M, Haraguchi M, Sumizawa T, Yamada K, Akiyama S.

Biochem Biophys Res Commun. 2006 Mar 31;342(1):280-5. Epub 2006 Feb 6.

PMID:
16480951
17.

Direct activation of the human major vault protein gene by DNA-damaging agents.

Shimamoto Y, Sumizawa T, Haraguchi M, Gotanda T, Jueng HC, Furukawa T, Sakata R, Akiyama S.

Oncol Rep. 2006 Mar;15(3):645-52.

PMID:
16465425
18.

Protection against DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase.

Jeung HC, Che XF, Haraguchi M, Zhao HY, Furukawa T, Gotanda T, Zheng CL, Tsuneyoshi K, Sumizawa T, Roh JK, Akiyama S.

FEBS Lett. 2006 Feb 20;580(5):1294-302. Epub 2006 Jan 26.

19.

Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.

Tsuneyoshi K, Haraguchi M, Hongye Z, Gotanda T, Tachiwada T, Sumizawa T, Furukawa T, Baba M, Akiyama S, Nakagawa M.

Cancer Lett. 2006 Dec 8;244(2):239-46. Epub 2006 Feb 7.

PMID:
16457948
21.

MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (beta-D-glucuronate).

Noguchi T, Ren XQ, Aoki S, Igarashi Y, Che XF, Nakajima Y, Takahashi H, Mitsuo R, Tsujikawa K, Sumizawa T, Haraguchi M, Kobayashi M, Goto S, Kanehisa M, Aikou T, Akiyama S, Furukawa T.

Biochem Pharmacol. 2005 Oct 1;70(7):1056-65.

PMID:
16098482
22.

Cepharanthine potently enhances the sensitivity of anticancer agents in K562 cells.

Ikeda R, Che XF, Yamaguchi T, Ushiyama M, Zheng CL, Okumura H, Takeda Y, Shibayama Y, Nakamura K, Jeung HC, Furukawa T, Sumizawa T, Haraguchi M, Akiyama S, Yamada K.

Cancer Sci. 2005 Jun;96(6):372-6.

23.

Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents.

Jeung HC, Che XF, Haraguchi M, Furukawa T, Zheng CL, Sumizawa T, Rha SY, Roh JK, Akiyama S.

Biochem Pharmacol. 2005 Jul 1;70(1):13-21.

PMID:
15907805
24.

GSH inhibits trypsinization of the C-terminal half of human MRP1.

Ren XQ, Furukawa T, Nakajima Y, Takahashi H, Aoki S, Sumizawa T, Haraguchi M, Kobayashi M, Chijiiwa K, Akiyama S.

J Biol Chem. 2005 Feb 18;280(7):6231-7. Epub 2004 Dec 3.

25.

Characterization of MVP and VPARP assembly into vault ribonucleoprotein complexes.

Zheng CL, Sumizawa T, Che XF, Tsuyama S, Furukawa T, Haraguchi M, Gao H, Gotanda T, Jueng HC, Murata F, Akiyama S.

Biochem Biophys Res Commun. 2005 Jan 7;326(1):100-7.

PMID:
15567158
26.

The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.

Akiyama S, Furukawa T, Sumizawa T, Takebayashi Y, Nakajima Y, Shimaoka S, Haraguchi M.

Cancer Sci. 2004 Nov;95(11):851-7. Review.

27.

Function of the ABC signature sequences in the human multidrug resistance protein 1.

Ren XQ, Furukawa T, Haraguchi M, Sumizawa T, Aoki S, Kobayashi M, Akiyama S.

Mol Pharmacol. 2004 Jun;65(6):1536-42.

PMID:
15155846
28.

Inhibition of metastasis of tumor cells overexpressing thymidine phosphorylase by 2-deoxy-L-ribose.

Nakajima Y, Gotanda T, Uchimiya H, Furukawa T, Haraguchi M, Ikeda R, Sumizawa T, Yoshida H, Akiyama S.

Cancer Res. 2004 Mar 1;64(5):1794-801.

29.

[Thymidine phosphorylase inhibits apoptosis induced by anticancer agents].

Ikeda R, Furukawa T, Sumizawa T, Haraguchi M, Oiso S, Inoue I, Yamada K, Akiyama S.

Nihon Yakurigaku Zasshi. 2003 Nov;122 Suppl:84P-86P. Japanese.

PMID:
14727531
30.

Binding site(s) on P-glycoprotein for a newly synthesized photoaffinity analog of agosterol A.

Mitsuo M, Noguchi T, Nakajima Y, Aoki S, Ren XQ, Sumizawa T, Haraguchi M, Kobayashi M, Baba M, Nagata Y, Akiyama S, Furukawa T.

Oncol Res. 2003;14(1):39-48.

PMID:
14552590
31.

Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells.

Mukai M, Che XF, Furukawa T, Sumizawa T, Aoki S, Ren XQ, Haraguchi M, Sugimoto Y, Kobayashi M, Takamatsu H, Akiyama S.

Cancer Sci. 2003 Jun;94(6):557-63.

32.

Localization of the GSH-dependent photolabelling site of an agosterol A analog on human MRP1.

Ren XQ, Furukawa T, Aoki S, Sumizawa T, Haraguchi M, Che XF, Kobayashi M, Akiyama S.

Br J Pharmacol. 2003 Apr;138(8):1553-61.

33.

Thymidine phosphorylase inhibits apoptosis induced by cisplatin.

Ikeda R, Furukawa T, Mitsuo R, Noguchi T, Kitazono M, Okumura H, Sumizawa T, Haraguchi M, Che XF, Uchimiya H, Nakajima Y, Ren XQ, Oiso S, Inoue I, Yamada K, Akiyama S.

Biochem Biophys Res Commun. 2003 Feb 7;301(2):358-63.

PMID:
12565868
34.

A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4.

Ren XQ, Furukawa T, Aoki S, Sumizawa T, Haraguchi M, Nakajima Y, Ikeda R, Kobayashi M, Akiyama S.

Biochemistry. 2002 Dec 3;41(48):14132-40.

PMID:
12450376
35.

Reversal of P-glycoprotein mediated multidrug resistance by a newly synthesized 1,4-benzothiazipine derivative, JTV-519.

Che XF, Nakajima Y, Sumizawa T, Ikeda R, Ren XQ, Zheng CL, Mukai M, Furukawa T, Haraguchi M, Gao H, Sugimoto Y, Akiyama S.

Cancer Lett. 2002 Dec 10;187(1-2):111-9.

PMID:
12359358
36.

Augmentation of the activity of an immunotoxin, anti-Tac(Fv)-PE40KDEL, in T cell lines infected with human T cell leukemia virus type-I.

Ohno N, Kreitman RJ, Saito T, Masamoto I, Uozumi K, Hanada S, Takeuchi S, Furukawa T, Sumizawa T, Arima T, Akiyama S.

Leuk Lymphoma. 2002 Apr;43(4):885-8.

PMID:
12153180
37.

Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice.

Haraguchi M, Tsujimoto H, Fukushima M, Higuchi I, Kuribayashi H, Utsumi H, Nakayama A, Hashizume Y, Hirato J, Yoshida H, Hara H, Hamano S, Kawaguchi H, Furukawa T, Miyazono K, Ishikawa F, Toyoshima H, Kaname T, Komatsu M, Chen ZS, Gotanda T, Tachiwada T, Sumizawa T, Miyadera K, Osame M, Yoshida H, Noda T, Yamada Y, Akiyama S.

Mol Cell Biol. 2002 Jul;22(14):5212-21.

38.

Enhanced nucleotide excision repair in cisplatin resistant human KB carcinoma cells.

Mukai M, Kanzaki A, Chen ZS, Miyashita H, Sumizawa T, Furukawa T, Haraguchi M, Takebayashi Y, Takamatsu H, Akiyama S.

Oncol Rep. 2002 Jul-Aug;9(4):839-44.

PMID:
12066219
39.

Suppression of thymidine phosphorylase-mediated angiogenesis and tumor growth by 2-deoxy-L-ribose.

Uchimiya H, Furukawa T, Okamoto M, Nakajima Y, Matsushita S, Ikeda R, Gotanda T, Haraguchi M, Sumizawa T, Ono M, Kuwano M, Kanzaki T, Akiyama S.

Cancer Res. 2002 May 15;62(10):2834-9.

40.

Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose.

Ikeda R, Furukawa T, Kitazono M, Ishitsuka K, Okumura H, Tani A, Sumizawa T, Haraguchi M, Komatsu M, Uchimiya H, Ren XQ, Motoya T, Yamada K, Akiyama S.

Biochem Biophys Res Commun. 2002 Mar 8;291(4):806-12.

PMID:
11866437
41.

Prognostic significance of multidrug resistance protein in adult T-cell leukemia.

Ohno N, Tani A, Chen ZS, Uozumi K, Hanada S, Akiba S, Ren XQ, Furukawa T, Sumizawa T, Arima T, Akiyama SI.

Clin Cancer Res. 2001 Oct;7(10):3120-6.

42.

Expression of functional lung resistance--related protein predicts poor outcome in adult T-cell leukemia.

Ohno N, Tani A, Uozumi K, Hanada S, Furukawa T, Akiba S, Sumizawa T, Utsunomiya A, Arima T, Akiyama S.

Blood. 2001 Aug 15;98(4):1160-5.

PMID:
11493465
43.

Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function.

Chen ZS, Aoki S, Komatsu M, Ueda K, Sumizawa T, Furukawa T, Okumura H, Ren XQ, Belinsky MG, Lee K, Kruh GD, Kobayashi M, Akiyama S.

Int J Cancer. 2001 Jul 1;93(1):107-13.

44.

Glutathione-dependent binding of a photoaffinity analog of agosterol A to the C-terminal half of human multidrug resistance protein.

Ren XQ, Furukawa T, Aoki S, Nakajima T, Sumizawa T, Haraguchi M, Chen ZS, Kobayashi M, Akiyama S.

J Biol Chem. 2001 Jun 22;276(25):23197-206. Epub 2001 Apr 11.

45.

Functional comparison between YCF1 and MRP1 expressed in Sf21 insect cells.

Ren XQ, Furukawa T, Chen ZS, Okumura H, Aoki S, Sumizawa T, Tani A, Komatsu M, Mei XD, Akiyama S.

Biochem Biophys Res Commun. 2000 Apr 13;270(2):608-15.

PMID:
10753671
46.

Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells.

Kitazono M, Okumura H, Ikeda R, Sumizawa T, Furukawa T, Nagayama S, Seto K, Aikou T, Akiyama S.

Int J Cancer. 2001 Jan 1;91(1):126-31.

47.

Reversal of P-glycoprotein and multidrug-resistance protein-mediated drug resistance in KB cells by 5-O-benzoylated taxinine K.

Okumura H, Chen ZS, Sakou M, Sumizawa T, Furukawa T, Komatsu M, Ikeda R, Suzuki H, Hirota K, Aikou T, Akiyama SI.

Mol Pharmacol. 2000 Dec;58(6):1563-9.

PMID:
11093797
48.

The role of thymidine phosphorylase in the pathogenesis of allergic rhinitis.

Nishimoto K, Matsune S, Miyadera K, Takebayashi Y, Furukawa T, Sumizawa T, Akiyama SI, Kurono Y.

Acta Otolaryngol. 2000 Aug;120(5):644-8.

PMID:
11039877
49.

Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance.

Komatsu M, Sumizawa T, Mutoh M, Chen ZS, Terada K, Furukawa T, Yang XL, Gao H, Miura N, Sugiyama T, Akiyama S.

Cancer Res. 2000 Mar 1;60(5):1312-6.

50.

[Mechanisms for resistance to anticancer agents and the reversal of the resistance].

Akiyama S, Chen ZS, Kitazono M, Sumizawa T, Furukawa T, Aikou T.

Hum Cell. 1999 Sep;12(3):95-102. Review. Japanese.

PMID:
10695015

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