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Items: 10

1.

LPA Induces Keratinocyte Differentiation and Promotes Skin Barrier Function through the LPAR1/LPAR5-RHO-ROCK-SRF Axis.

Sumitomo A, Siriwach R, Thumkeo D, Ito K, Nakagawa R, Tanaka N, Tanabe K, Watanabe A, Kishibe M, Ishida-Yamamoto A, Honda T, Kabashima K, Aoki J, Narumiya S.

J Invest Dermatol. 2019 May;139(5):1010-1022. doi: 10.1016/j.jid.2018.10.034. Epub 2018 Nov 14.

PMID:
30447238
2.

A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia.

Sumitomo A, Horike K, Hirai K, Butcher N, Boot E, Sakurai T, Nucifora FC Jr, Bassett AS, Sawa A, Tomoda T.

Sci Adv. 2018 Aug 15;4(8):eaar6637. doi: 10.1126/sciadv.aar6637. eCollection 2018 Aug.

3.

Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons.

Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, Sakurai T, Ishizuka K, Sawa A, Tomoda T.

Hum Mol Genet. 2018 Sep 15;27(18):3165-3176. doi: 10.1093/hmg/ddy219.

PMID:
29893844
4.

Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in Fez1-Deficient Mice.

Sumitomo A, Saka A, Ueta K, Horike K, Hirai K, Gamo NJ, Hikida T, Nakayama KI, Sawa A, Sakurai T, Tomoda T.

Mol Neuropsychiatry. 2018 May;3(4):223-233. doi: 10.1159/000488081. Epub 2018 Apr 26.

5.

[11C](R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice.

Ooms M, Tsujikawa T, Lohith TG, Mabins SN, Zoghbi SS, Sumitomo A, Jaaro-Peled H, Kimura Y, Telu S, Pike VW, Tomoda T, Innis RB, Sawa A, Fujita M.

J Cereb Blood Flow Metab. 2019 Jul;39(7):1306-1313. doi: 10.1177/0271678X18758997. Epub 2018 Feb 12.

PMID:
29430995
6.

Ulk1 protects against ethanol-induced neuronal stress and cognition-related behavioral deficits.

Sumitomo A, Ueta K, Mauchi S, Hirai K, Horike K, Hikida T, Sakurai T, Sawa A, Tomoda T.

Neurosci Res. 2017 Apr;117:54-61. doi: 10.1016/j.neures.2016.12.004. Epub 2016 Dec 23.

PMID:
28017600
7.

DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1.

Niwa M, Cash-Padgett T, Kubo KI, Saito A, Ishii K, Sumitomo A, Taniguchi Y, Ishizuka K, Jaaro-Peled H, Tomoda T, Nakajima K, Sawa A, Kamiya A.

Mol Psychiatry. 2016 Nov;21(11):1488-1489. doi: 10.1038/mp.2016.154. Epub 2016 Sep 6. No abstract available.

8.

Utility and validity of DISC1 mouse models in biological psychiatry.

Tomoda T, Sumitomo A, Jaaro-Peled H, Sawa A.

Neuroscience. 2016 May 3;321:99-107. doi: 10.1016/j.neuroscience.2015.12.061. Epub 2016 Jan 6. Review.

9.

Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells.

Hasegawa N, Sumitomo A, Fujita A, Aritome N, Mizuta S, Matsui K, Ishino R, Inoue K, Urahama N, Nose J, Mukohara T, Kamoshida S, Roeder RG, Ito M.

Mol Cell Biol. 2012 Apr;32(8):1483-95. doi: 10.1128/MCB.05245-11. Epub 2012 Feb 13.

10.

The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression.

Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K, Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M.

Mol Cell Biol. 2010 Oct;30(20):4818-27. doi: 10.1128/MCB.01348-09. Epub 2010 Aug 16.

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