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Items: 35

1.

Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia.

Sumi-Ichinose C, Suganuma Y, Kano T, Ihira N, Nomura H, Ikemoto K, Hata T, Katoh S, Ichinose H, Kondo K.

Physiol Rep. 2017 Mar;5(6). pii: e13196. doi: 10.14814/phy2.13196.

2.

Disturbed biopterin and folate metabolism in the Qdpr-deficient mouse.

Xu F, Sudo Y, Sanechika S, Yamashita J, Shimaguchi S, Honda S, Sumi-Ichinose C, Mori-Kojima M, Nakata R, Furuta T, Sakurai M, Sugimoto M, Soga T, Kondo K, Ichinose H.

FEBS Lett. 2014 Nov 3;588(21):3924-31. doi: 10.1016/j.febslet.2014.09.004. Epub 2014 Sep 19.

3.

Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia.

Onouchi T, Kobayashi K, Sakai K, Shimomura A, Smits R, Sumi-Ichinose C, Kurosumi M, Takao K, Nomura R, Iizuka-Kogo A, Suzuki H, Kondo K, Akiyama T, Miyakawa T, Fodde R, Senda T.

Mol Brain. 2014 Mar 29;7:21. doi: 10.1186/1756-6606-7-21.

4.

GTP cyclohydrolase regulation: implications for brain development and function.

Ichinose H, Homma D, Sumi-Ichinose C, Nomura T, Kondo K.

Adv Pharmacol. 2013;68:23-35. doi: 10.1016/B978-0-12-411512-5.00003-8. Review.

PMID:
24054139
5.

Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy.

Yagi H, Sanechika S, Ichinose H, Sumi-Ichinose C, Mizukami H, Urabe M, Ozawa K, Kume A.

Neuroreport. 2012 Jan 4;23(1):30-4. doi: 10.1097/WNR.0b013e32834e3a87.

PMID:
22107842
6.

Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection.

Tokuoka H, Muramatsu S, Sumi-Ichinose C, Sakane H, Kojima M, Aso Y, Nomura T, Metzger D, Ichinose H.

J Biol Chem. 2011 Dec 16;286(50):43549-58. doi: 10.1074/jbc.M111.284729. Epub 2011 Oct 25.

7.

Cilostazol inhibits cytokine-induced tetrahydrobiopterin biosynthesis in human umbilical vein endothelial cells.

Shiraishi H, Ikemoto K, Tada S, Udagawa Y, Ohtsuki M, Sumi-Ichinose C, Kondo K, Nomura T.

J Atheroscler Thromb. 2011;18(4):312-7. Epub 2011 Jan 6.

8.

Partial biopterin deficiency disturbs postnatal development of the dopaminergic system in the brain.

Homma D, Sumi-Ichinose C, Tokuoka H, Ikemoto K, Nomura T, Kondo K, Katoh S, Ichinose H.

J Biol Chem. 2011 Jan 14;286(2):1445-52. doi: 10.1074/jbc.M110.159426. Epub 2010 Nov 9.

9.
10.

Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons.

Kadkhodaei B, Ito T, Joodmardi E, Mattsson B, Rouillard C, Carta M, Muramatsu S, Sumi-Ichinose C, Nomura T, Metzger D, Chambon P, Lindqvist E, Larsson NG, Olson L, Björklund A, Ichinose H, Perlmann T.

J Neurosci. 2009 Dec 16;29(50):15923-32. doi: 10.1523/JNEUROSCI.3910-09.2009.

11.

Metabolism of tetrahydrobiopterin: its relevance in monoaminergic neurons and neurological disorders.

Ichinose H, Nomura T, Sumi-Ichinose C.

Chem Rec. 2008;8(6):378-85. doi: 10.1002/tcr.20166.

PMID:
19107867
12.

Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia.

Sato K, Sumi-Ichinose C, Kaji R, Ikemoto K, Nomura T, Nagatsu I, Ichinose H, Ito M, Sako W, Nagahiro S, Graybiel AM, Goto S.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12551-6. doi: 10.1073/pnas.0806065105. Epub 2008 Aug 19.

13.

2,4-Diamino-6-hydroxypyrimidine (DAHP) suppresses cytokine-induced VCAM-1 expression on the cell surface of human umbilical vein endothelial cells in a BH(4)-independent manner.

Ikemoto K, Matsumoto T, Ohtsuki M, Itoh M, Tada S, Udagawa Y, Sumi-Ichinose C, Kondo K, Nomura T.

Biochim Biophys Acta. 2008 Jul-Aug;1780(7-8):960-5. doi: 10.1016/j.bbagen.2008.03.012. Epub 2008 Mar 30.

PMID:
18423409
14.

A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice--as a mouse model for Parkinson's disease.

Takazawa C, Fujimoto K, Homma D, Sumi-Ichinose C, Nomura T, Ichinose H, Katoh S.

Biochem Biophys Res Commun. 2008 Mar 21;367(4):787-92. doi: 10.1016/j.bbrc.2008.01.028. Epub 2008 Jan 15.

PMID:
18201550
15.

Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice.

Kojima M, Suzuki T, Maekawa T, Ishii S, Sumi-Ichinose C, Nomura T, Ichinose H.

J Neurosci Res. 2008 Feb 15;86(3):544-52.

PMID:
17896792
16.

Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and region-specific monoaminergic abnormalities.

Sumi-Ichinose C, Urano F, Shimomura A, Sato T, Ikemoto K, Shiraishi H, Senda T, Ichinose H, Nomura T.

J Neurochem. 2005 Nov;95(3):703-14. Epub 2005 Aug 31.

17.

cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.

Shiraishi H, Kato T, Atsuta K, Sumi-Ichinose C, Ohtsuki M, Itoh M, Hishida H, Tada S, Udagawa Y, Nagatsu T, Hagino Y, Ichinose H, Nomura T.

J Pharmacol Sci. 2003 Nov;93(3):265-71.

18.

[Regulations and pathophysiological significance of the biosynthesis of tetrahydrobiopterin in human endothelial cells].

Shiraishi H, Ohtsuki M, Sumi-Ichinose C, Nomura T.

Nihon Yakurigaku Zasshi. 2002 Nov;120(1):73P-75P. Japanese.

PMID:
12491785
19.

cAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.

Ohtsuki M, Shiraishi H, Kato T, Kuroda R, Tazawa M, Sumi-Ichinose C, Tada S, Udagawa Y, Itoh M, Hishida H, Ichinose H, Nagatsu T, Hagino Y, Nomura T.

Life Sci. 2002 Mar 22;70(18):2187-98.

PMID:
12002810
20.

[Perspectives on tetrahydrobiopterin research].

Sumi-Ichinose C, Ohtsuki M, Shiraishi H, Nomura T.

Nihon Yakurigaku Zasshi. 2001 Dec;118(6):371-7. Review. Japanese.

PMID:
11778454
21.

Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice.

Sumi-Ichinose C, Urano F, Kuroda R, Ohye T, Kojima M, Tazawa M, Shiraishi H, Hagino Y, Nagatsu T, Nomura T, Ichinose H.

J Biol Chem. 2001 Nov 2;276(44):41150-60. Epub 2001 Aug 21.

22.

Effects of sulfhydryl reagents on nitric oxide release from a nitric oxide donor NOR 3 in the presence of rat hepatocytes.

Nomura H, Tazawa M, Kuroda R, Shiraishi H, Sumi-Ichinose C, Matsui S, Ohtsuki M, Hagino Y, Nomura T.

Pharmacol Toxicol. 2000 Nov;87(5):246-8. No abstract available.

PMID:
11129506
23.

GTP cyclohydrolase I from Tetrahymena pyriformis: cloning of cDNA and expression.

Tazawa M, Ohtsuki M, Sumi-Ichinose C, Shiraishi H, Kuroda R, Hagino Y, Nakashima S, Nozawa Y, Ichinose H, Nagatsu T, Nomura T.

Comp Biochem Physiol B Biochem Mol Biol. 2000 Sep;127(1):65-73.

PMID:
11126753
24.

Molecular cloning of the human Nurr1 gene: characterization of the human gene and cDNAs.

Ichinose H, Ohye T, Suzuki T, Sumi-Ichinose C, Nomura T, Hagino Y, Nagatsu T.

Gene. 1999 Apr 16;230(2):233-9.

PMID:
10216262
25.

Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I.

Nomura T, Tazawa M, Ohtsuki M, Sumi-Ichinose C, Hagino Y, Ota A, Nakashima A, Mori K, Sugimoto T, Ueno O, Nozawa Y, Ichinose H, Nagatsu T.

Comp Biochem Physiol B Biochem Mol Biol. 1998 Aug;120(4):753-60.

PMID:
9854821
26.

Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism.

Nomura T, Ohtsuki M, Matsui S, Sumi-Ichinose C, Nomura H, Hagino Y.

Pharmacol Toxicol. 1998 Jan;82(1):40-6.

PMID:
9527646
27.

SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells.

Sumi-Ichinose C, Ichinose H, Metzger D, Chambon P.

Mol Cell Biol. 1997 Oct;17(10):5976-86.

28.

Analysis of an alternative promoter that regulates tissue-specific expression of the human aromatic L-amino acid decarboxylase gene in cultured cell lines.

Sumi-Ichinose C, Hasegawa S, Ohtsuki M, Nomura H, Nomura T, Hagino Y, Fujita K, Nagatsu T.

J Neural Transm (Vienna). 1996;103(1-2):1-15.

PMID:
9026364
29.

Metabolic effects of glibenclamide in isolated rat hepatocytes in the absence of extracellular Ca2+.

Nomura T, Ohtsuki M, Watanabe T, Hasegawa S, Matsui S, Tomita A, Sumi-Ichinose C, Nomura H, Hagino Y.

Jpn J Pharmacol. 1995 Oct;69(2):173-6.

30.

Analysis of the alternative promoters that regulate tissue-specific expression of human aromatic L-amino acid decarboxylase.

Sumi-Ichinose C, Hasegawa S, Ichinose H, Sawada H, Kobayashi K, Sakai M, Fujii T, Nomura H, Nomura T, Nagatsu I, et al.

J Neurochem. 1995 Feb;64(2):514-24.

PMID:
7830043
31.

Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma.

Nomura T, Ohtsuki M, Matsui S, Sumi-Ichinose C, Nomura H, Hagino Y, Iwase K, Ichinose H, Fujita K, Nagatsu T.

J Neural Transm Gen Sect. 1995;101(1-3):237-42.

PMID:
8695054
32.

Alpha 1B-adrenoceptor-mediated stimulation of Ca2+ mobilization and cAMP accumulation in isolated rat hepatocytes.

Nomura T, Kondo H, Hasegawa S, Watanabe T, Yokoyama R, Ukai K, Tachibana M, Sumi-Ichinose C, Nomura H, Hagino Y.

Eur J Pharmacol. 1993 Jul 15;246(2):113-20.

PMID:
8104151
33.

Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase I.

Nomura T, Ichinose H, Sumi-Ichinose C, Nomura H, Hagino Y, Fujita K, Nagatsu T.

Biochem Biophys Res Commun. 1993 Mar 15;191(2):523-7.

PMID:
8461009
34.

Tissue-specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase.

Ichinose H, Sumi-Ichinose C, Ohye T, Hagino Y, Fujita K, Nagatsu T.

Biochemistry. 1992 Nov 24;31(46):11546-50.

PMID:
1445888
35.

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