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Items: 41

1.

A Mobile Genetic Element Promotes the Association Between Serotype M28 Group A Streptococcus Isolates and Cases of Puerperal Sepsis.

Jain I, Sarkar P, Danger JL, Medicielo J, Roshika R, Calfee G, Ramalinga A, Burgess C, Sumby P.

J Infect Dis. 2019 Apr 23. pii: jiz195. doi: 10.1093/infdis/jiz195. [Epub ahead of print]

PMID:
31107945
2.

Phenotypic Variation in the Group A Streptococcus Due to Natural Mutation of the Accessory Protein-Encoding Gene rocA.

Sarkar P, Danger JL, Jain I, Meadows LA, Beam C, Medicielo J, Burgess C, Musser JM, Sumby P.

mSphere. 2018 Oct 17;3(5). pii: e00519-18. doi: 10.1128/mSphere.00519-18.

3.

Identification and Characterization of Serotype-Specific Variation in Group A Streptococcus Pilus Expression.

Calfee G, Danger JL, Jain I, Miller EW, Sarkar P, Tjaden B, Kreikemeyer B, Sumby P.

Infect Immun. 2018 Jan 22;86(2). pii: e00792-17. doi: 10.1128/IAI.00792-17. Print 2018 Feb.

4.

RocA Is an Accessory Protein to the Virulence-Regulating CovRS Two-Component System in Group A Streptococcus.

Jain I, Miller EW, Danger JL, Pflughoeft KJ, Sumby P.

Infect Immun. 2017 Oct 18;85(11). pii: e00274-17. doi: 10.1128/IAI.00274-17. Print 2017 Nov.

5.

Regulatory gene mutation: a driving force behind group a Streptococcus strain- and serotype-specific variation.

Sarkar P, Sumby P.

Mol Microbiol. 2017 Feb;103(4):576-589. doi: 10.1111/mmi.13584. Epub 2016 Dec 19. Review.

6.

Multimerization of the Virulence-Enhancing Group A Streptococcus Transcription Factor RivR Is Required for Regulatory Activity.

Ramalinga A, Danger JL, Makthal N, Kumaraswami M, Sumby P.

J Bacteriol. 2016 Dec 13;199(1). pii: e00452-16. doi: 10.1128/JB.00452-16. Print 2017 Jan 1.

7.

The FasX Small Regulatory RNA Negatively Regulates the Expression of Two Fibronectin-Binding Proteins in Group A Streptococcus.

Danger JL, Makthal N, Kumaraswami M, Sumby P.

J Bacteriol. 2015 Dec;197(23):3720-30. doi: 10.1128/JB.00530-15. Epub 2015 Sep 21.

8.

Regulatory rewiring confers serotype-specific hyper-virulence in the human pathogen group A Streptococcus.

Miller EW, Danger JL, Ramalinga AB, Horstmann N, Shelburne SA, Sumby P.

Mol Microbiol. 2015 Oct;98(3):473-89. doi: 10.1111/mmi.13136. Epub 2015 Aug 14.

9.

Reply to "A truncation in the regulator RocA underlies heightened capsule expression in serotype M3 group A streptococci".

Miller EW, Pflughoeft KJ, Sumby P.

Infect Immun. 2015 Apr;83(4):1734. doi: 10.1128/IAI.03162-14. No abstract available.

10.
11.

The small regulatory RNA FasX enhances group A Streptococcus virulence and inhibits pilus expression via serotype-specific targets.

Danger JL, Cao TN, Cao TH, Sarkar P, Treviño J, Pflughoeft KJ, Sumby P.

Mol Microbiol. 2015 Apr;96(2):249-62. doi: 10.1111/mmi.12935. Epub 2015 Feb 4.

12.

Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus.

Horstmann N, Sahasrabhojane P, Saldaña M, Ajami NJ, Flores AR, Sumby P, Liu CG, Yao H, Su X, Thompson E, Shelburne SA.

Infect Immun. 2015 Mar;83(3):1068-77. doi: 10.1128/IAI.02659-14. Epub 2015 Jan 5.

13.

Transcription of the Streptococcus pyogenes hyaluronic acid capsule biosynthesis operon is regulated by previously unknown upstream elements.

Falaleeva M, Zurek OW, Watkins RL, Reed RW, Ali H, Sumby P, Voyich JM, Korotkova N.

Infect Immun. 2014 Dec;82(12):5293-307. doi: 10.1128/IAI.02035-14. Epub 2014 Oct 6.

14.

RNA-mediated regulation in Gram-positive pathogens: an overview punctuated with examples from the group A Streptococcus.

Miller EW, Cao TN, Pflughoeft KJ, Sumby P.

Mol Microbiol. 2014 Oct;94(1):9-20. doi: 10.1111/mmi.12742. Epub 2014 Aug 21. Review.

15.

Natural disruption of two regulatory networks in serotype M3 group A Streptococcus isolates contributes to the virulence factor profile of this hypervirulent serotype.

Cao TN, Liu Z, Cao TH, Pflughoeft KJ, Treviño J, Danger JL, Beres SB, Musser JM, Sumby P.

Infect Immun. 2014 May;82(5):1744-54. doi: 10.1128/IAI.01639-13. Epub 2014 Feb 10.

16.

Computational analysis of bacterial RNA-Seq data.

McClure R, Balasubramanian D, Sun Y, Bobrovskyy M, Sumby P, Genco CA, Vanderpool CK, Tjaden B.

Nucleic Acids Res. 2013 Aug;41(14):e140. doi: 10.1093/nar/gkt444. Epub 2013 May 28.

17.

RivR is a negative regulator of virulence factor expression in group A Streptococcus.

Treviño J, Liu Z, Cao TN, Ramirez-Peña E, Sumby P.

Infect Immun. 2013 Jan;81(1):364-72. doi: 10.1128/IAI.00703-12. Epub 2012 Nov 12.

18.

The small regulatory RNA FasX controls pilus expression and adherence in the human bacterial pathogen group A Streptococcus.

Liu Z, Treviño J, Ramirez-Peña E, Sumby P.

Mol Microbiol. 2012 Oct;86(1):140-54. doi: 10.1111/j.1365-2958.2012.08178.x. Epub 2012 Aug 6.

19.

Evolution of diversity in epidemics revealed by analysis of the human bacterial pathogen group A Streptococcus.

Carroll RK, Beres SB, Sitkiewicz I, Peterson L, Matsunami RK, Engler DA, Flores AR, Sumby P, Musser JM.

Epidemics. 2011 Sep;3(3-4):159-70. doi: 10.1016/j.epidem.2011.07.001. Epub 2011 Aug 5.

PMID:
22094339
20.

The group A Streptococcus small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA transcript.

Ramirez-Peña E, Treviño J, Liu Z, Perez N, Sumby P.

Mol Microbiol. 2010 Dec;78(6):1332-47. doi: 10.1111/j.1365-2958.2010.07427.x. Epub 2010 Oct 22.

21.

Bacillus anthracis sin locus and regulation of secreted proteases.

Pflughoeft KJ, Sumby P, Koehler TM.

J Bacteriol. 2011 Feb;193(3):631-9. doi: 10.1128/JB.01083-10. Epub 2010 Dec 3.

22.

A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection.

Shelburne SA, Olsen RJ, Suber B, Sahasrabhojane P, Sumby P, Brennan RG, Musser JM.

PLoS Pathog. 2010 Mar 19;6(3):e1000817. doi: 10.1371/journal.ppat.1000817.

23.

The 4.5S RNA component of the signal recognition particle is required for group A Streptococcus virulence.

Treviño J, Perez N, Sumby P.

Microbiology. 2010 May;156(Pt 5):1342-50. doi: 10.1099/mic.0.036558-0. Epub 2010 Jan 28.

24.

A genome-wide analysis of small regulatory RNAs in the human pathogen group A Streptococcus.

Perez N, Treviño J, Liu Z, Ho SC, Babitzke P, Sumby P.

PLoS One. 2009 Nov 2;4(11):e7668. doi: 10.1371/journal.pone.0007668.

25.

The secreted esterase of group a streptococcus is important for invasive skin infection and dissemination in mice.

Zhu H, Liu M, Sumby P, Lei B.

Infect Immun. 2009 Dec;77(12):5225-32. doi: 10.1128/IAI.00636-09. Epub 2009 Oct 5.

26.

CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes.

Treviño J, Perez N, Ramirez-Peña E, Liu Z, Shelburne SA 3rd, Musser JM, Sumby P.

Infect Immun. 2009 Aug;77(8):3141-9. doi: 10.1128/IAI.01560-08. Epub 2009 May 18.

27.

A non-human primate model of acute group a Streptococcus pharyngitis.

Sumby P, Tart AH, Musser JM.

Methods Mol Biol. 2008;431:255-67.

PMID:
18287762
28.

A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus.

Shelburne SA 3rd, Keith D, Horstmann N, Sumby P, Davenport MT, Graviss EA, Brennan RG, Musser JM.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1698-703. doi: 10.1073/pnas.0711767105. Epub 2008 Jan 29. Erratum in: Proc Natl Acad Sci U S A. 2009 May 26;106(21):8790.

29.

A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response.

Sumby P, Zhang S, Whitney AR, Falugi F, Grandi G, Graviss EA, Deleo FR, Musser JM.

Infect Immun. 2008 Mar;76(3):978-85. doi: 10.1128/IAI.01354-07. Epub 2008 Jan 3.

30.

Regulation of polysaccharide utilization contributes to the persistence of group a streptococcus in the oropharynx.

Shelburne SA 3rd, Okorafor N, Sitkiewicz I, Sumby P, Keith D, Patel P, Austin C, Graviss EA, Musser JM.

Infect Immun. 2007 Jun;75(6):2981-90. Epub 2007 Apr 2.

31.

MalE of group A Streptococcus participates in the rapid transport of maltotriose and longer maltodextrins.

Shelburne SA 3rd, Fang H, Okorafor N, Sumby P, Sitkiewicz I, Keith D, Patel P, Austin C, Graviss EA, Musser JM, Chow DC.

J Bacteriol. 2007 Apr;189(7):2610-7. Epub 2007 Jan 26.

32.

Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2.

Sitkiewicz I, Nagiec MJ, Sumby P, Butler SD, Cywes-Bentley C, Musser JM.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):16009-14. Epub 2006 Oct 16.

33.

Maltodextrin utilization plays a key role in the ability of group A Streptococcus to colonize the oropharynx.

Shelburne SA 3rd, Sumby P, Sitkiewicz I, Okorafor N, Granville C, Patel P, Voyich J, Hull R, DeLeo FR, Musser JM.

Infect Immun. 2006 Aug;74(8):4605-14.

34.

Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus.

Beres SB, Richter EW, Nagiec MJ, Sumby P, Porcella SF, DeLeo FR, Musser JM.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):7059-64. Epub 2006 Apr 24.

35.

Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity.

Sumby P, Whitney AR, Graviss EA, DeLeo FR, Musser JM.

PLoS Pathog. 2006 Jan;2(1):e5. Epub 2006 Jan 27.

36.

Central role of a bacterial two-component gene regulatory system of previously unknown function in pathogen persistence in human saliva.

Shelburne SA 3rd, Sumby P, Sitkiewicz I, Granville C, DeLeo FR, Musser JM.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16037-42. Epub 2005 Oct 25.

37.

Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events.

Sumby P, Porcella SF, Madrigal AG, Barbian KD, Virtaneva K, Ricklefs SM, Sturdevant DE, Graham MR, Vuopio-Varkila J, Hoe NP, Musser JM.

J Infect Dis. 2005 Sep 1;192(5):771-82. Epub 2005 Jul 29.

PMID:
16088826
38.

Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response.

Sumby P, Barbian KD, Gardner DJ, Whitney AR, Welty DM, Long RD, Bailey JR, Parnell MJ, Hoe NP, Adams GG, Deleo FR, Musser JM.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1679-84. Epub 2005 Jan 24.

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