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Items: 19

1.

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling.

Mayer AE, Löffler MC, Loza Valdés AE, Schmitz W, El-Merahbi R, Viera JT, Erk M, Zhang T, Braun U, Heikenwalder M, Leitges M, Schulze A, Sumara G.

Sci Signal. 2019 Aug 6;12(593). pii: eaav9150. doi: 10.1126/scisignal.aav9150.

PMID:
31387939
2.

Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity.

Löffler MC, Mayer AE, Trujillo Viera J, Loza Valdes A, El-Merahbi R, Ade CP, Karwen T, Schmitz W, Slotta A, Erk M, Janaki-Raman S, Matesanz N, Torres JL, Marcos M, Sabio G, Eilers M, Schulze A, Sumara G.

EMBO J. 2018 Nov 15;37(22). pii: e99182. doi: 10.15252/embj.201899182. Epub 2018 Nov 2.

PMID:
30389661
3.

Ndrg1 promotes adipocyte differentiation and sustains their function.

Cai K, El-Merahbi R, Loeffler M, Mayer AE, Sumara G.

Sci Rep. 2017 Aug 3;7(1):7191. doi: 10.1038/s41598-017-07497-x.

4.

Cross-talk between insulin and Wnt signaling in preadipocytes. ROLE OF Wnt CO-RECEPTOR LDL RECEPTOR-RELATED PROTEIN-5 (LRP5).

Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR.

J Biol Chem. 2016 Aug 5;291(32):16878. doi: 10.1074/jbc.A111.337048. No abstract available.

5.

Phospholipases D1 and D2 Suppress Appetite and Protect against Overweight.

Trujillo Viera J, El-Merahbi R, Nieswandt B, Stegner D, Sumara G.

PLoS One. 2016 Jun 14;11(6):e0157607. doi: 10.1371/journal.pone.0157607. eCollection 2016.

6.

The roles of peripheral serotonin in metabolic homeostasis.

El-Merahbi R, Löffler M, Mayer A, Sumara G.

FEBS Lett. 2015 Jul 8;589(15):1728-34. doi: 10.1016/j.febslet.2015.05.054. Epub 2015 Jun 9. Review.

7.

The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart.

Windak R, Müller J, Felley A, Akhmedov A, Wagner EF, Pedrazzini T, Sumara G, Ricci R.

PLoS One. 2013 Sep 10;8(9):e73294. doi: 10.1371/journal.pone.0073294. eCollection 2013.

8.

Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung.

Ittner A, Block H, Reichel CA, Varjosalo M, Gehart H, Sumara G, Gstaiger M, Krombach F, Zarbock A, Ricci R.

J Exp Med. 2012 Nov 19;209(12):2229-46. doi: 10.1084/jem.20120677. Epub 2012 Nov 5.

9.

Gut-derived serotonin is a multifunctional determinant to fasting adaptation.

Sumara G, Sumara O, Kim JK, Karsenty G.

Cell Metab. 2012 Nov 7;16(5):588-600. doi: 10.1016/j.cmet.2012.09.014. Epub 2012 Oct 18.

10.

Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5).

Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR.

J Biol Chem. 2012 Apr 6;287(15):12016-26. doi: 10.1074/jbc.M111.337048. Epub 2012 Feb 15. Erratum in: J Biol Chem. 2016 Aug 5;291(32):16878.

11.

Endocrine regulation of male fertility by the skeleton.

Oury F, Sumara G, Sumara O, Ferron M, Chang H, Smith CE, Hermo L, Suarez S, Roth BL, Ducy P, Karsenty G.

Cell. 2011 Mar 4;144(5):796-809. doi: 10.1016/j.cell.2011.02.004. Epub 2011 Feb 17.

12.

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

Fuchs S, Herzog D, Sumara G, Büchmann-Møller S, Civenni G, Wu X, Chrostek-Grashoff A, Suter U, Ricci R, Relvas JB, Brakebusch C, Sommer L.

Cell Stem Cell. 2009 Mar 6;4(3):236-47. doi: 10.1016/j.stem.2009.01.017.

13.

Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.

Sumara G, Formentini I, Collins S, Sumara I, Windak R, Bodenmiller B, Ramracheya R, Caille D, Jiang H, Platt KA, Meda P, Aebersold R, Rorsman P, Ricci R.

Cell. 2009 Jan 23;136(2):235-48. doi: 10.1016/j.cell.2008.11.018. Epub 2009 Jan 8.

14.

Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion.

Falk S, Wurdak H, Ittner LM, Ille F, Sumara G, Schmid MT, Draganova K, Lang KS, Paratore C, Leveen P, Suter U, Karlsson S, Born W, Ricci R, Götz M, Sommer L.

Cell Stem Cell. 2008 May 8;2(5):472-83. doi: 10.1016/j.stem.2008.03.006.

15.

A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

Sumara I, Quadroni M, Frei C, Olma MH, Sumara G, Ricci R, Peter M.

Dev Cell. 2007 Jun;12(6):887-900.

16.

c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity.

Stepniak E, Ricci R, Eferl R, Sumara G, Sumara I, Rath M, Hui L, Wagner EF.

Genes Dev. 2006 Aug 15;20(16):2306-14.

17.

"Jnking" atherosclerosis.

Sumara G, Belwal M, Ricci R.

Cell Mol Life Sci. 2005 Nov;62(21):2487-94. Review.

PMID:
16231089
18.

Distinct functions of junD in cardiac hypertrophy and heart failure.

Ricci R, Eriksson U, Oudit GY, Eferl R, Akhmedov A, Sumara I, Sumara G, Kassiri Z, David JP, Bakiri L, Sasse B, Idarraga MH, Rath M, Kurz D, Theussl HC, Perriard JC, Backx P, Penninger JM, Wagner EF.

Genes Dev. 2005 Jan 15;19(2):208-13.

19.

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis.

Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, Akhmedov A, Hersberger M, Eriksson U, Eberli FR, Becher B, Borén J, Chen M, Cybulsky MI, Moore KJ, Freeman MW, Wagner EF, Matter CM, Lüscher TF.

Science. 2004 Nov 26;306(5701):1558-61.

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