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Items: 17

1.

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors.

Drilon A, Nagasubramanian R, Blake JF, Ku N, Tuch BB, Ebata K, Smith S, Lauriault V, Kolakowski GR, Brandhuber BJ, Larsen PD, Bouhana KS, Winski SL, Hamor R, Wu WI, Parker A, Morales TH, Sullivan FX, DeWolf WE, Wollenberg LA, Gordon PR, Douglas-Lindsay DN, Scaltriti M, Benayed R, Raj S, Hanusch B, Schram AM, Jonsson P, Berger MF, Hechtman JF, Taylor BS, Andrews S, Rothenberg SM, Hyman DM.

Cancer Discov. 2017 Sep;7(9):963-972. doi: 10.1158/2159-8290.CD-17-0507. Epub 2017 Jun 3.

2.

Single-agent inhibition of Chk1 is antiproliferative in human cancer cell lines in vitro and inhibits tumor xenograft growth in vivo.

Davies KD, Humphries MJ, Sullivan FX, von Carlowitz I, Le Huerou Y, Mohr PJ, Wang B, Blake JF, Lyon MA, Gunawardana I, Chicarelli M, Wallace E, Gross S.

Oncol Res. 2011;19(7):349-63.

PMID:
21936404
3.

Chk1 inhibition and Wee1 inhibition combine synergistically to impede cellular proliferation.

Davies KD, Cable PL, Garrus JE, Sullivan FX, von Carlowitz I, Huerou YL, Wallace E, Woessner RD, Gross S.

Cancer Biol Ther. 2011 Nov 1;12(9):788-96. doi: 10.4161/cbt.12.9.17673. Epub 2011 Nov 1.

PMID:
21892012
4.

Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase.

Olland AM, Underwood KW, Czerwinski RM, Lo MC, Aulabaugh A, Bard J, Stahl ML, Somers WS, Sullivan FX, Chopra R.

J Biol Chem. 2002 Feb 1;277(5):3698-707. Epub 2001 Nov 9.

5.

Structural and kinetic analysis of Escherichia coli GDP-mannose 4,6 dehydratase provides insights into the enzyme's catalytic mechanism and regulation by GDP-fucose.

Somoza JR, Menon S, Schmidt H, Joseph-McCarthy D, Dessen A, Stahl ML, Somers WS, Sullivan FX.

Structure. 2000 Feb 15;8(2):123-35.

7.

Molecular cloning of human GDP-mannose 4,6-dehydratase and reconstitution of GDP-fucose biosynthesis in vitro.

Sullivan FX, Kumar R, Kriz R, Stahl M, Xu GY, Rouse J, Chang XJ, Boodhoo A, Potvin B, Cumming DA.

J Biol Chem. 1998 Apr 3;273(14):8193-202.

8.
9.

The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis.

MalĂ˝ P, Thall A, Petryniak B, Rogers CE, Smith PL, Marks RM, Kelly RJ, Gersten KM, Cheng G, Saunders TL, Camper SA, Camphausen RT, Sullivan FX, Isogai Y, Hindsgaul O, von Andrian UH, Lowe JB.

Cell. 1996 Aug 23;86(4):643-53.

10.

Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein.

Yuen CT, Lawson AM, Chai W, Larkin M, Stoll MS, Stuart AC, Sullivan FX, Ahern TJ, Feizi T.

Biochemistry. 1992 Sep 29;31(38):9126-31.

PMID:
1382586
11.

Mutational analysis of parasite trypanothione reductase: acquisition of glutathione reductase activity in a triple mutant.

Sullivan FX, Sobolov SB, Bradley M, Walsh CT.

Biochemistry. 1991 Mar 19;30(11):2761-7.

PMID:
2007114
12.

Cloning, sequencing, overproduction and purification of trypanothione reductase from Trypanosoma cruzi.

Sullivan FX, Walsh CT.

Mol Biochem Parasitol. 1991 Jan;44(1):145-7. No abstract available.

PMID:
2011150
13.
14.

Characterization of two RNA-catalyzed RNA cleavage reactions.

Sampson JR, Sullivan FX, Behlen LS, DiRenzo AB, Uhlenbeck OC.

Cold Spring Harb Symp Quant Biol. 1987;52:267-75. No abstract available.

PMID:
2456879
15.

New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing.

Inoue T, Sullivan FX, Cech TR.

J Mol Biol. 1986 May 5;189(1):143-65.

PMID:
2431151
16.

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