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Items: 10


Comparisons of voltage-gated sodium channel structures with open and closed gates and implications for state-dependent drug design.

Montini G, Booker J, Sula A, Wallace BA.

Biochem Soc Trans. 2018 Dec 17;46(6):1567-1575. doi: 10.1042/BST20180295. Epub 2018 Oct 31. Review.


Lipid binding attenuates channel closure of the outer membrane protein OmpF.

Liko I, Degiacomi MT, Lee S, Newport TD, Gault J, Reading E, Hopper JTS, Housden NG, White P, Colledge M, Sula A, Wallace BA, Kleanthous C, Stansfeld PJ, Bayley H, Benesch JLP, Allison TM, Robinson CV.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6691-6696. doi: 10.1073/pnas.1721152115. Epub 2018 Jun 11.


Thermal melt circular dichroism spectroscopic studies for identifying stabilising amphipathic molecules for the voltage-gated sodium channel NavMs.

Ireland SM, Sula A, Wallace BA.

Biopolymers. 2018 Aug;109(8):e23067. doi: 10.1002/bip.23067. Epub 2017 Sep 19.


Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase.

Lichman BR, Sula A, Pesnot T, Hailes HC, Ward JM, Keep NH.

Biochemistry. 2017 Oct 10;56(40):5274-5277. doi: 10.1021/acs.biochem.7b00769. Epub 2017 Sep 20.


Interpreting the functional role of a novel interaction motif in prokaryotic sodium channels.

Sula A, Wallace BA.

J Gen Physiol. 2017 Jun 5;149(6):613-622. doi: 10.1085/jgp.201611740. Epub 2017 May 18. Review.


The complete structure of an activated open sodium channel.

Sula A, Booker J, Ng LC, Naylor CE, DeCaen PG, Wallace BA.

Nat Commun. 2017 Feb 16;8:14205. doi: 10.1038/ncomms14205.


Isolated pores dissected from human two-pore channel 2 are functional.

Penny CJ, Rahman T, Sula A, Miles AJ, Wallace BA, Patel S.

Sci Rep. 2016 Dec 12;6:38426. doi: 10.1038/srep38426.


Molecular basis of ion permeability in a voltage-gated sodium channel.

Naylor CE, Bagnéris C, DeCaen PG, Sula A, Scaglione A, Clapham DE, Wallace BA.

EMBO J. 2016 Apr 15;35(8):820-30. doi: 10.15252/embj.201593285. Epub 2016 Feb 12.


'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile.

Lichman BR, Gershater MC, Lamming ED, Pesnot T, Sula A, Keep NH, Hailes HC, Ward JM.

FEBS J. 2015 Mar;282(6):1137-51. doi: 10.1111/febs.13208. Epub 2015 Feb 9.


Crystal structures of the human Dysferlin inner DysF domain.

Sula A, Cole AR, Yeats C, Orengo C, Keep NH.

BMC Struct Biol. 2014 Jan 17;14:3. doi: 10.1186/1472-6807-14-3.

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