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Items: 1 to 50 of 194

1.

Modeling Corticosteroid Pharmacogenomics and Proteomics in Rat Liver.

Ayyar VS, Sukumaran S, DuBois DC, Almon RR, Jusko WJ.

J Pharmacol Exp Ther. 2018 Aug 7. pii: jpet.118.251959. doi: 10.1124/jpet.118.251959. [Epub ahead of print]

2.

A PKPD analysis of circulating biomarkers and their relationship to tumor response in atezolizumab-treated non-small cell lung cancer patients.

Netterberg I, Li CC, Molinero L, Budha N, Sukumaran S, Stroh M, Jonsson N, Friberg L.

Clin Pharmacol Ther. 2018 Jul 30. doi: 10.1002/cpt.1198. [Epub ahead of print]

PMID:
30058723
3.

Genomic-enabled Prediction Accuracies Increased by Modeling Genotype × Environment Interaction in Durum Wheat.

Sukumaran S, Jarquin D, Crossa J, Reynolds M.

Plant Genome. 2018 Jul;11(2). doi: 10.3835/plantgenome2017.12.0112.

4.

Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment.

Sukumaran S, Watanabe N, Bajgain P, Raja K, Mohammed S, Fisher WE, Brenner MK, Leen AM, Vera JF.

Cancer Discov. 2018 Aug;8(8):972-987. doi: 10.1158/2159-8290.CD-17-1298. Epub 2018 Jun 7.

PMID:
29880586
5.

Ecological quality status evaluation of a monsoonal tropical estuary using benthic indices: comparison via a seasonal approach.

Dias HQ, Sukumaran S, Srinivas T, Mulik J.

Environ Sci Pollut Res Int. 2018 Aug;25(23):22672-22688. doi: 10.1007/s11356-018-2344-0. Epub 2018 May 30.

PMID:
29851015
6.

CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation.

Bajgain P, Tawinwung S, D'Elia L, Sukumaran S, Watanabe N, Hoyos V, Lulla P, Brenner MK, Leen AM, Vera JF.

J Immunother Cancer. 2018 May 10;6(1):34. doi: 10.1186/s40425-018-0347-5.

7.

Design, graph theoretical analysis and in silico modeling of Dunaliella bardawil biomass encapsulated keratin nanoparticles: a scaffold for effective glucose utilization.

Kunjiappan S, Panneerselvam T, Prasad P, Sukumaran S, Somasundaram B, Sankaranarayanan M, Murugan I, Parasuraman P.

Biomed Mater. 2018 May 4;13(4):045012. doi: 10.1088/1748-605X/aabcea.

PMID:
29727301
8.

Receptor/gene/protein-mediated signaling connects methylprednisolone exposure to metabolic and immune-related pharmacodynamic actions in liver.

Ayyar VS, Sukumaran S, DuBois DC, Almon RR, Qu J, Jusko WJ.

J Pharmacokinet Pharmacodyn. 2018 Aug;45(4):557-575. doi: 10.1007/s10928-018-9585-x. Epub 2018 Apr 27.

PMID:
29704219
9.

Design of a heme-binding peptide motif adopting a β-hairpin conformation.

Nagarajan D, Sukumaran S, Deka G, Krishnamurthy K, Atreya HS, Chandra N.

J Biol Chem. 2018 Jun 15;293(24):9412-9422. doi: 10.1074/jbc.RA118.001768. Epub 2018 Apr 25.

PMID:
29695501
10.

Online information and support needs of women with advanced breast cancer: a qualitative analysis.

Kemp E, Koczwara B, Butow P, Turner J, Girgis A, Schofield P, Hulbert-Williams N, Levesque J, Spence D, Vatandoust S, Kichenadasse G, Roy A, Sukumaran S, Karapetis CS, Richards C, Fitzgerald M, Beatty L.

Support Care Cancer. 2018 Apr 24. doi: 10.1007/s00520-018-4206-1. [Epub ahead of print]

PMID:
29693203
11.

Unique glandular ex-vivo Th1 and Th17 receptor motifs in Sjögren's syndrome patients using single-cell analysis.

Voigt A, Bohn K, Sukumaran S, Stewart CM, Bhattacharya I, Nguyen CQ.

Clin Immunol. 2018 Jul;192:58-67. doi: 10.1016/j.clim.2018.04.009. Epub 2018 Apr 19.

PMID:
29679709
12.

Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases.

Stefanich EG, Rae J, Sukumaran S, Lutman J, Lekkerkerker A, Ouyang W, Wang X, Lee D, Danilenko DM, Diehl L, Loyet KM, Herman A.

Biochem Pharmacol. 2018 Jun;152:224-235. doi: 10.1016/j.bcp.2018.03.031. Epub 2018 Mar 31.

PMID:
29608910
13.

Enhancement of drug permeability across blood brain barrier using nanoparticles in meningitis.

Nair KGS, Ramaiyan V, Sukumaran SK.

Inflammopharmacology. 2018 Jun;26(3):675-684. doi: 10.1007/s10787-018-0468-y. Epub 2018 Mar 26. Review.

PMID:
29582240
14.

Genome-Wide Association Analyses Identify QTL Hotspots for Yield and Component Traits in Durum Wheat Grown under Yield Potential, Drought, and Heat Stress Environments.

Sukumaran S, Reynolds MP, Sansaloni C.

Front Plant Sci. 2018 Feb 6;9:81. doi: 10.3389/fpls.2018.00081. eCollection 2018.

15.

Correction to: Genetic analysis of multi-environmental spring wheat trials identifies genomic regions for locus-specific trade-offs for grain weight and grain number.

Sukumaran S, Lopes M, Dreisigacker S, Reynolds M.

Theor Appl Genet. 2018 Apr;131(4):999. doi: 10.1007/s00122-018-3066-x.

PMID:
29453525
16.

Gli3 is a negative regulator of Tas1r3-expressing taste cells.

Qin Y, Sukumaran SK, Jyotaki M, Redding K, Jiang P, Margolskee RF.

PLoS Genet. 2018 Feb 7;14(2):e1007058. doi: 10.1371/journal.pgen.1007058. eCollection 2018 Feb.

17.

gPKPDSim: a SimBiology®-based GUI application for PKPD modeling in drug development.

Hosseini I, Gajjala A, Bumbaca Yadav D, Sukumaran S, Ramanujan S, Paxson R, Gadkar K.

J Pharmacokinet Pharmacodyn. 2018 Apr;45(2):259-275. doi: 10.1007/s10928-017-9562-9. Epub 2018 Jan 4.

18.

Genetic analysis of multi-environmental spring wheat trials identifies genomic regions for locus-specific trade-offs for grain weight and grain number.

Sukumaran S, Lopes M, Dreisigacker S, Reynolds M.

Theor Appl Genet. 2018 Apr;131(4):985-998. doi: 10.1007/s00122-017-3037-7. Epub 2017 Dec 7. Erratum in: Theor Appl Genet. 2018 Feb 16;:.

PMID:
29218375
19.

Dwell Time of Stentriever Influences Complete Revascularization and First-Pass TICI 3 Revascularization in Acute Large Vessel Occlusive Stroke.

Kannath SK, Rajan JE, Sylaja PN, Sarma PS, Sukumaran S, Sreedharan SE, Kapilamoorthy TR.

World Neurosurg. 2018 Feb;110:169-173. doi: 10.1016/j.wneu.2017.10.155. Epub 2017 Nov 4.

PMID:
29113900
20.

Infantile-Onset Fever and Urticaria.

Sukumaran S, Vijayan V.

JAMA Pediatr. 2017 Nov 1;171(11):1122-1123. doi: 10.1001/jamapediatrics.2017.2531. No abstract available.

PMID:
28975215
21.

Single-cell analysis reveals sexually dimorphic repertoires of Interferon-γ and IL-17A producing T cells in salivary glands of Sjögren's syndrome mice.

Wanchoo A, Voigt A, Sukumaran S, Stewart CM, Bhattacharya I, Nguyen CQ.

Sci Rep. 2017 Oct 2;7(1):12512. doi: 10.1038/s41598-017-12627-6.

22.

Effectiveness of speech language therapy either alone or with add-on computer-based language therapy software (Malayalam version) for early post stroke aphasia: A feasibility study.

Kesav P, Vrinda SL, Sukumaran S, Sarma PS, Sylaja PN.

J Neurol Sci. 2017 Sep 15;380:137-141. doi: 10.1016/j.jns.2017.07.010. Epub 2017 Jul 8.

PMID:
28870554
23.

Adaptation of Lactobacillus acidophilus to Thermal Stress Yields a Thermotolerant Variant Which Also Exhibits Improved Survival at pH 2.

Kulkarni S, Haq SF, Samant S, Sukumaran S.

Probiotics Antimicrob Proteins. 2017 Aug 30. doi: 10.1007/s12602-017-9321-7. [Epub ahead of print]

PMID:
28853009
24.

Whole transcriptome profiling of taste bud cells.

Sukumaran SK, Lewandowski BC, Qin Y, Kotha R, Bachmanov AA, Margolskee RF.

Sci Rep. 2017 Aug 8;7(1):7595. doi: 10.1038/s41598-017-07746-z.

25.

Short-term exposure of erythropoietin impairs endothelial function through inhibition of nitric oxide production and eNOS mRNA expression in the rat pulmonary artery.

Sultan F, Singh TU, Kumar T, Rungsung S, Rabha DJ, Vishwakarma A, Sukumaran SV, Kandasamy A, Parida S.

Pharmacol Rep. 2017 Aug;69(4):658-665. doi: 10.1016/j.pharep.2017.02.003. Epub 2017 Feb 4.

PMID:
28527876
26.

Comparative efficacy of benthic biotic indices in assessing the Ecological Quality Status (EcoQS) of the stressed Ulhas estuary, India.

Mulik J, Sukumaran S, Srinivas T, Vijapure T.

Mar Pollut Bull. 2017 Jul 15;120(1-2):192-202. doi: 10.1016/j.marpolbul.2017.05.014. Epub 2017 May 13.

PMID:
28511940
27.

Hypercholesterolemia impairs oxytocin-induced uterine contractility in late pregnant mouse.

Padol AR, Sukumaran SV, Sadam A, Kesavan M, Arunvikram K, Verma AD, Srivastava V, Panigrahi M, Singh TU, Telang AG, Mishra SK, Parida S.

Reproduction. 2017 May;153(5):565-576. doi: 10.1530/REP-16-0446.

28.

Pathogenic multiple antimicrobial resistant Escherichia coli serotypes in recreational waters of Mumbai, India: a potential public health risk.

Maloo A, Fulke AB, Mulani N, Sukumaran S, Ram A.

Environ Sci Pollut Res Int. 2017 Apr;24(12):11504-11517. doi: 10.1007/s11356-017-8760-8. Epub 2017 Mar 18.

PMID:
28316051
29.

Functional proteomic analysis of corticosteroid pharmacodynamics in rat liver: Relationship to hepatic stress, signaling, energy regulation, and drug metabolism.

Ayyar VS, Almon RR, DuBois DC, Sukumaran S, Qu J, Jusko WJ.

J Proteomics. 2017 May 8;160:84-105. doi: 10.1016/j.jprot.2017.03.007. Epub 2017 Mar 14.

30.

Pre-treatment serum lactate dehydrogenase as a biomarker in small cell lung cancer.

Hsieh AH, Tahkar H, Koczwara B, Kichenadasse G, Beckmann K, Karapetis C, Sukumaran S.

Asia Pac J Clin Oncol. 2018 Apr;14(2):e64-e70. doi: 10.1111/ajco.12674. Epub 2017 Mar 8.

PMID:
28276170
31.

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.

Li J, Stagg NJ, Johnston J, Harris MJ, Menzies SA, DiCara D, Clark V, Hristopoulos M, Cook R, Slaga D, Nakamura R, McCarty L, Sukumaran S, Luis E, Ye Z, Wu TD, Sumiyoshi T, Danilenko D, Lee GY, Totpal K, Ellerman D, Hötzel I, James JR, Junttila TT.

Cancer Cell. 2017 Mar 13;31(3):383-395. doi: 10.1016/j.ccell.2017.02.001. Epub 2017 Mar 2.

32.

Impact of obstructive sleep apnea on neurological recovery after ischemic stroke: A prospective study.

Menon D, Sukumaran S, Varma R, Radhakrishnan A.

Acta Neurol Scand. 2017 Nov;136(5):419-426. doi: 10.1111/ane.12740. Epub 2017 Feb 15.

PMID:
28205227
33.

Fine-tuning the CAR spacer improves T-cell potency.

Watanabe N, Bajgain P, Sukumaran S, Ansari S, Heslop HE, Rooney CM, Brenner MK, Leen AM, Vera JF.

Oncoimmunology. 2016 Nov 8;5(12):e1253656. doi: 10.1080/2162402X.2016.1253656. eCollection 2016.

34.

Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer.

Mohammed S, Sukumaran S, Bajgain P, Watanabe N, Heslop HE, Rooney CM, Brenner MK, Fisher WE, Leen AM, Vera JF.

Mol Ther. 2017 Jan 4;25(1):249-258. doi: 10.1016/j.ymthe.2016.10.016. Epub 2017 Jan 4.

35.

CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly.

Sukumaran SK, Stumpf M, Salamon S, Ahmad I, Bhattacharya K, Fischer S, Müller R, Altmüller J, Budde B, Thiele H, Tariq M, Malik NA, Nürnberg P, Baig SM, Hussain MS, Noegel AA.

Mol Genet Genomics. 2017 Apr;292(2):365-383. doi: 10.1007/s00438-016-1277-x. Epub 2016 Dec 21.

36.

Phenotypic and genome-wide association analysis of spike ethylene in diverse wheat genotypes under heat stress.

Valluru R, Reynolds MP, Davies WJ, Sukumaran S.

New Phytol. 2017 Apr;214(1):271-283. doi: 10.1111/nph.14367. Epub 2016 Dec 5.

37.

An anti-CD3/anti-CLL-1 bispecific antibody for the treatment of acute myeloid leukemia.

Leong SR, Sukumaran S, Hristopoulos M, Totpal K, Stainton S, Lu E, Wong A, Tam L, Newman R, Vuillemenot BR, Ellerman D, Gu C, Mathieu M, Dennis MS, Nguyen A, Zheng B, Zhang C, Lee G, Chu YW, Prell RA, Lin K, Laing ST, Polson AG.

Blood. 2017 Feb 2;129(5):609-618. doi: 10.1182/blood-2016-08-735365. Epub 2016 Dec 1.

38.

Genomic Prediction with Pedigree and Genotype × Environment Interaction in Spring Wheat Grown in South and West Asia, North Africa, and Mexico.

Sukumaran S, Crossa J, Jarquin D, Lopes M, Reynolds MP.

G3 (Bethesda). 2017 Feb 9;7(2):481-495. doi: 10.1534/g3.116.036251.

39.

Pregnancy screening prior to chemotherapy administration.

Hu L, Kichenadasse G, Martin H, Roy A, Sukumaran S, Vatandoust S, Koczwara B, Karapetis CS.

Intern Med J. 2016 Oct;46(10):1222-1224. doi: 10.1111/imj.13214.

PMID:
27734613
40.

Development and Translational Application of an Integrated, Mechanistic Model of Antibody-Drug Conjugate Pharmacokinetics.

Sukumaran S, Zhang C, Leipold DD, Saad OM, Xu K, Gadkar K, Samineni D, Wang B, Milojic-Blair M, Carrasco-Triguero M, Rubinfeld B, Fielder P, Lin K, Ramanujan S.

AAPS J. 2017 Jan;19(1):130-140. doi: 10.1208/s12248-016-9993-z. Epub 2016 Sep 27.

PMID:
27679517
41.

Polychaete Community of a Marine Protected Area along the West Coast of India-Prior and Post the Tropical Cyclone, Phyan.

Sukumaran S, Vijapure T, Kubal P, Mulik J, Rokade MA, Salvi S, Thomas J, Naidu VS.

PLoS One. 2016 Aug 24;11(8):e0159368. doi: 10.1371/journal.pone.0159368. eCollection 2016.

42.

Synthesis, Biological Evaluation and Molecular Modelling of 2'-Hydroxychalcones as Acetylcholinesterase Inhibitors.

Sukumaran SD, Chee CF, Viswanathan G, Buckle MJ, Othman R, Abd Rahman N, Chung LY.

Molecules. 2016 Jul 22;21(7). pii: E955. doi: 10.3390/molecules21070955.

43.

Goserelin toxicities and preferences for ovarian suppression method in pre-menopausal women with breast cancer.

Hsieh AH, Kichenadasse G, Vatandoust S, Roy A, Sukumaran S, Karapetis CS, Martin H, Chong LC, Koczwara B.

Intern Med J. 2016 Oct;46(10):1153-1159. doi: 10.1111/imj.13169.

PMID:
27389059
44.

MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria.

Tan CT, Zhou QL, Su YC, Fu NY, Chang HC, Tao RN, Sukumaran SK, Baksh S, Tan YJ, Sabapathy K, Yu CD, Yu VC.

Cell Rep. 2016 Jun 28;16(1):174-185. doi: 10.1016/j.celrep.2016.05.068. Epub 2016 Jun 16.

45.

Chikungunya Virus Disease: An Emerging Challenge for the Rheumatologist.

Vijayan V, Sukumaran S.

J Clin Rheumatol. 2016 Jun;22(4):203-11. doi: 10.1097/RHU.0000000000000396. Review.

PMID:
27219309
46.

Single-cell antibody nanowells: a novel technology in detecting anti-SSA/Ro60- and anti-SSB/La autoantibody-producing cells in peripheral blood of rheumatic disease patients.

Esfandiary L, Gupta N, Voigt A, Wanchoo A, Chan EK, Sukumaran S, Nguyen CQ.

Arthritis Res Ther. 2016 May 17;18(1):107. doi: 10.1186/s13075-016-1010-5.

47.

A Pilot Study of Self-Management-based Nutrition and Physical Activity Intervention in Cancer Survivors.

Miller M, Zrim S, Lawn S, Woodman R, Leggett S, Jones L, Karapetis C, Kichenadasse G, Sukumaran S, Roy AC, Koczwara B.

Nutr Cancer. 2016 Jul;68(5):762-71. doi: 10.1080/01635581.2016.1170169. Epub 2016 May 13.

PMID:
27176450
48.

Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.

Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):6035-40. doi: 10.1073/pnas.1520843113. Epub 2016 May 9.

49.

Evaluation of role of telmisartan in combination with 5-fluorouracil in gastric cancer cachexia.

Sukumaran S, Patel HJ, Patel BM.

Life Sci. 2016 Jun 1;154:15-23. doi: 10.1016/j.lfs.2016.04.029. Epub 2016 Apr 24.

PMID:
27117583
50.

Macroscopic technique for the evaluation of oral tongue tumour thickness: a reliable intraoperative method.

Pandey M, Vidhyadharan S, Puthalath U, Veeraraghavan R, Sukumaran SV, Prasad C, Iyer S, Thankappan K.

Int J Oral Maxillofac Surg. 2016 Aug;45(8):933-7. doi: 10.1016/j.ijom.2016.03.008. Epub 2016 Mar 28.

PMID:
27034158

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