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Items: 11

1.

Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors.

Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick G, Wong TT, Okoro JI, Scales RM, Tumwebaze PK, Rosenthal PJ, Kafsack BFC, Cooper RA, Meinke PT, Kirkman LA, Lin G.

J Med Chem. 2019 Jul 11;62(13):6137-6145. doi: 10.1021/acs.jmedchem.9b00363. Epub 2019 Jun 20.

PMID:
31177777
2.

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.

Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R, Ling Y, Tumwebaze PK, Sukenick G, Shi L, Vendome J, Bhanot P, Rosenthal PJ, Aso K, Foley MA, Cooper RA, Kafsack B, Doggett JS, Nathan CF, Lin G.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6863-E6870. doi: 10.1073/pnas.1806109115. Epub 2018 Jul 2.

3.

Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.

Hsu HC, Singh PK, Fan H, Wang R, Sukenick G, Nathan C, Lin G, Li H.

Biochemistry. 2017 Jan 10;56(1):324-333. doi: 10.1021/acs.biochem.6b01107. Epub 2016 Dec 27.

4.

Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.

Sula Karreci E, Fan H, Uehara M, Mihali AB, Singh PK, Kurdi AT, Solhjou Z, Riella LV, Ghobrial I, Laragione T, Routray S, Assaker JP, Wang R, Sukenick G, Shi L, Barrat FJ, Nathan CF, Lin G, Azzi J.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8425-E8432. doi: 10.1073/pnas.1618548114. Epub 2016 Dec 12.

5.

High-Throughput Indirect Quantitation of 13C Enriched Metabolites Using 1H NMR.

Di Gialleonardo V, Tee SS, Aldeborgh HN, Miloushev VZ, Cunha LS, Sukenick GD, Keshari KR.

Anal Chem. 2016 Nov 15;88(22):11147-11153. Epub 2016 Oct 26.

6.

Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment.

Simões RV, Serganova IS, Kruchevsky N, Leftin A, Shestov AA, Thaler HT, Sukenick G, Locasale JW, Blasberg RG, Koutcher JA, Ackerstaff E.

Neoplasia. 2015 Aug;17(8):671-84. doi: 10.1016/j.neo.2015.08.005.

7.

Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment.

Rattigan YI, Patel BB, Ackerstaff E, Sukenick G, Koutcher JA, Glod JW, Banerjee D.

Exp Cell Res. 2012 Feb 15;318(4):326-35. doi: 10.1016/j.yexcr.2011.11.014. Epub 2011 Dec 8.

8.

Redundant function of cmaA2 and mmaA2 in Mycobacterium tuberculosis cis cyclopropanation of oxygenated mycolates.

Barkan D, Rao V, Sukenick GD, Glickman MS.

J Bacteriol. 2010 Jul;192(14):3661-8. doi: 10.1128/JB.00312-10. Epub 2010 May 14.

9.

Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy.

Muruganandham M, Alfieri AA, Matei C, Chen Y, Sukenick G, Schemainda I, Hasmann M, Saltz LB, Koutcher JA.

Clin Cancer Res. 2005 May 1;11(9):3503-13.

10.

Synthesis of selected LeY and KH-1 analogues: a medicinal chemistry approach to vaccine optimization.

Spassova MK, Bornmann WG, Ragupathi G, Sukenick G, Livingston PO, Danishefsky SJ.

J Org Chem. 2005 Apr 29;70(9):3383-95.

PMID:
15844973
11.

Synthesis and conformational analysis of (E)-9,10-dehydroepothilone B: a suggestive link between the chemistry and biology of epothilones.

Yoshimura F, Rivkin A, Gabarda AE, Chou TC, Dong H, Sukenick G, Morel FF, Taylor RE, Danishefsky SJ.

Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2518-21. No abstract available.

PMID:
12800175

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