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A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.

Vashisht Gopal YN, Gammon S, Prasad R, Knighton B, Pisaneschi F, Roszik J, Feng N, Johnson S, Pramanik S, Sudderth J, Sui D, Hudgens C, Fischer GM, Deng W, Reuben A, Peng W, Wang J, McQuade JL, Tetzlaff MT, Di Francesco ME, Marszalek J, Piwnica-Worms D, DeBerardinis RJ, Davies MA.

Clin Cancer Res. 2019 Aug 22. doi: 10.1158/1078-0432.CCR-19-0836. [Epub ahead of print]


Effective Delivery of Hypertrophic miRNA Inhibitor by Cholesterol-Containing Nanocarriers for Preventing Pressure Overload Induced Cardiac Hypertrophy.

Zhi Y, Xu C, Sui D, Du J, Xu FJ, Li Y.

Adv Sci (Weinh). 2019 Apr 6;6(11):1900023. doi: 10.1002/advs.201900023. eCollection 2019 Jun 5.


Role of Immune Response, Inflammation, and Tumor Immune Response-Related Cytokines/Chemokines in Melanoma Progression.

Fang S, Xu T, Xiong M, Zhou X, Wang Y, Haydu LE, Ross MI, Gershenwald JE, Prieto VG, Cormier JN, Wargo J, Sui D, Wei Q, Amos CI, Lee JE.

J Invest Dermatol. 2019 Jun 7. pii: S0022-202X(19)31626-4. doi: 10.1016/j.jid.2019.03.1158. [Epub ahead of print]


The histidine-rich loop in the extracellular domain of ZIP4 binds zinc and plays a role in zinc transport.

Zhang T, Kuliyev E, Sui D, Hu J.

Biochem J. 2019 Jun 28;476(12):1791-1803. doi: 10.1042/BCJ20190108.


20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1.

Wang Y, Xu H, Fu W, Lu Z, Guo M, Wu X, Sun M, Liu Y, Yu X, Sui D.

Front Pharmacol. 2019 May 7;10:475. doi: 10.3389/fphar.2019.00475. eCollection 2019.


Early T precursor acute lymphoblastic leukaemia/lymphoma shows differential immunophenotypic characteristics including frequent CD33 expression and in vitro response to targeted CD33 therapy.

Khogeer H, Rahman H, Jain N, Angelova EA, Yang H, Quesada A, Ok CY, Sui D, Wei P, Al Fattani A, Pierce S, Loghavi S, Lamb A, Hu P, Thakral B, Kanagal-Shamanna R, Jorgensen JL, Jabbour EJ, Kantarjian HM, Medeiros LJ, Khoury JD.

Br J Haematol. 2019 Aug;186(4):538-548. doi: 10.1111/bjh.15960. Epub 2019 May 22.


A retrospective serological survey of hepatitis B virus infection in Northeast China.

Meng J, Xu H, Sui D, Jiang J, Li J, Gao Y, Niu J.

BMC Infect Dis. 2019 May 20;19(1):440. doi: 10.1186/s12879-019-4091-3.


Functional Connectivity Changes Across the Spectrum of Subjective Cognitive Decline, Amnestic Mild Cognitive Impairment and Alzheimer's Disease.

Wang Z, Qiao K, Chen G, Sui D, Dong HM, Wang YS, Li HJ, Lu J, Zuo XN, Han Y.

Front Neuroinform. 2019 Apr 24;13:26. doi: 10.3389/fninf.2019.00026. eCollection 2019.


CYP2C11 played a significant role in down-regulating rat blood pressure under the challenge of a high-salt diet.

Liu W, Sui D, Ye H, Ouyang Z, Wei Y.

PeerJ. 2019 Apr 23;7:e6807. doi: 10.7717/peerj.6807. eCollection 2019.


Functional criticality in the human brain: Physiological, behavioral and neurodevelopmental correlates.

Jiang L, Qiao K, Sui D, Zhang Z, Dong HM.

PLoS One. 2019 Mar 8;14(3):e0213690. doi: 10.1371/journal.pone.0213690. eCollection 2019.


B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density.

Aung PP, Parra ER, Barua S, Sui D, Ning J, Mino B, Ledesma DA, Curry JL, Nagarajan P, Torres-Cabala CA, Efstathiou E, Hoang AG, Wong MK, Wargo JA, Lazar AJ, Rao A, Prieto VG, Wistuba I, Tetzlaff MT.

Clin Cancer Res. 2019 Jun 1;25(11):3455-3467. doi: 10.1158/1078-0432.CCR-18-2355. Epub 2019 Feb 26.


Effects of CYP2C11 gene knockout on the pharmacokinetics and pharmacodynamics of warfarin in rats.

Ye H, Sui D, Liu W, Yuan Y, Ouyang Z, Wei Y.

Xenobiotica. 2019 Dec;49(12):1478-1484. doi: 10.1080/00498254.2019.1579006. Epub 2019 Feb 27.


Ginsenoside Re Improves Isoproterenol-Induced Myocardial Fibrosis and Heart Failure in Rats.

Wang QW, Yu XF, Xu HL, Zhao XZ, Sui DY.

Evid Based Complement Alternat Med. 2019 Jan 1;2019:3714508. doi: 10.1155/2019/3714508. eCollection 2019.


Alprostadil attenuates myocardial ischemia/reperfusion injury by promoting antioxidant activity and eNOS activation in rats.

Zhang L, Zhang Y, Yu X, Xu H, Sui D, Zhao X.

Acta Cir Bras. 2018 Dec;33(12):1067-1077. doi: 10.1590/s0102-865020180120000004.


Upregulation of Heme Oxygenase-1 by Hemin Alleviates Sepsis-Induced Muscle Wasting in Mice.

Yu X, Han W, Wang C, Sui D, Bian J, Bo L, Deng X.

Oxid Med Cell Longev. 2018 Nov 8;2018:8927104. doi: 10.1155/2018/8927104. eCollection 2018.


Rosuvastatin protects against oxidized low‑density lipoprotein‑induced endothelial cell injury of atherosclerosis in vitro.

Geng J, Xu H, Yu X, Xu G, Cao H, Lin G, Sui D.

Mol Med Rep. 2019 Jan;19(1):432-440. doi: 10.3892/mmr.2018.9666. Epub 2018 Nov 19.


A Hierarchical Silver-Nanowire-Graphene Host Enabling Ultrahigh Rates and Superior Long-Term Cycling of Lithium-Metal Composite Anodes.

Xue P, Liu S, Shi X, Sun C, Lai C, Zhou Y, Sui D, Chen Y, Liang J.

Adv Mater. 2018 Nov;30(44):e1804165. doi: 10.1002/adma.201804165. Epub 2018 Sep 24.


Neuroprotective effects of pramipexole transdermal patch in the MPTP-induced mouse model of Parkinson's disease.

Wang Y, Yu X, Zhang P, Ma Y, Wang L, Xu H, Sui D.

J Pharmacol Sci. 2018 Sep;138(1):31-37. doi: 10.1016/j.jphs.2018.08.008. Epub 2018 Aug 26.


Ghrelin Ameliorates Angiotensin II-Induced Myocardial Fibrosis by Upregulating Peroxisome Proliferator-Activated Receptor Gamma in Young Male Rats.

Wang Q, Sui X, Chen R, Ma PY, Teng YL, Ding T, Sui DJ, Yang P.

Biomed Res Int. 2018 Aug 5;2018:9897581. doi: 10.1155/2018/9897581. eCollection 2018.


Persistent IDH1/2 mutations in remission can predict relapse in patients with acute myeloid leukemia.

Ok CY, Loghavi S, Sui D, Wei P, Kanagal-Shamanna R, Yin CC, Zuo Z, Routbort MJ, Tang G, Tang Z, Jorgensen JL, Luthra R, Ravandi F, Kantarjian HM, DiNardo CD, Medeiros LJ, Wang SA, Patel KP.

Haematologica. 2019 Feb;104(2):305-311. doi: 10.3324/haematol.2018.191148. Epub 2018 Aug 31.


Vaspin protects rats against myocardial ischemia/reperfusion injury (MIRI) through the TLR4/NF-κB signaling pathway.

Yuan L, Dai X, Fu H, Sui D, Lin L, Yang L, Zha P, Wang X, Gong G.

Eur J Pharmacol. 2018 Sep 15;835:132-139. doi: 10.1016/j.ejphar.2018.07.052. Epub 2018 Jul 29.


Validation of the 2017 revision of the WHO chronic myelomonocytic leukemia categories.

Loghavi S, Sui D, Wei P, Garcia-Manero G, Pierce S, Routbort MJ, Jabbour EJ, Pemmaraju N, Kanagal-Shamanna R, Gur HD, Hu S, Zuo Z, Medeiros LJ, Kantarjian HM, Khoury JD.

Blood Adv. 2018 Aug 14;2(15):1807-1816. doi: 10.1182/bloodadvances.2018019224.


Flavonoid Extract from Propolis Inhibits Cardiac Fibrosis Triggered by Myocardial Infarction through Upregulation of SIRT1.

Wang Q, Sui X, Sui DJ, Yang P.

Evid Based Complement Alternat Med. 2018 Jun 27;2018:4957573. doi: 10.1155/2018/4957573. eCollection 2018.


Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5Kγ.

Zeng X, Uyar A, Sui D, Donyapour N, Wu D, Dickson A, Hu J.

Biochem J. 2018 Jul 26;475(14):2257-2269. doi: 10.1042/BCJ20180326.


MiR-29a-5p inhibits proliferation and invasion and induces apoptosis in endometrial carcinoma via targeting TPX2.

Jiang T, Sui D, You D, Yao S, Zhang L, Wang Y, Zhao J, Zhang Y.

Cell Cycle. 2018;17(10):1268-1278. doi: 10.1080/15384101.2018.1475829. Epub 2018 Jul 23.


Complications and Prevention Strategies of Oblique Lateral Interbody Fusion Technique.

Zeng ZY, Xu ZW, He DW, Zhao X, Ma WH, Ni WF, Song YX, Zhang JQ, Yu W, Fang XQ, Zhou ZJ, Xu NJ, Huang WJ, Hu ZC, Wu AL, Ji JF, Han JF, Fan SW, Zhao FD, Jin H, Pei F, Fan SY, Sui DX.

Orthop Surg. 2018 May;10(2):98-106. doi: 10.1111/os.12380.


Ginsenoside Re Attenuates Isoproterenol-Induced Myocardial Injury in Rats.

Wang QW, Yu XF, Xu HL, Jiang YC, Zhao XZ, Sui DY.

Evid Based Complement Alternat Med. 2018 Apr 22;2018:8637134. doi: 10.1155/2018/8637134. eCollection 2018.


Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.

Wang Y, Xu H, Lu Z, Yu X, Lv C, Tian Y, Sui D.

Exp Ther Med. 2018 Jun;15(6):4916-4924. doi: 10.3892/etm.2018.6067. Epub 2018 Apr 13.


20(S)-Protopanaxadiol-Induced Apoptosis in MCF-7 Breast Cancer Cell Line through the Inhibition of PI3K/AKT/mTOR Signaling Pathway.

Zhang H, Xu HL, Wang YC, Lu ZY, Yu XF, Sui DY.

Int J Mol Sci. 2018 Apr 2;19(4). pii: E1053. doi: 10.3390/ijms19041053.


Lobaplatin promotes radiosensitivity, induces apoptosis, attenuates cancer stemness and inhibits proliferation through PI3K/AKT pathway in esophageal squamous cell carcinoma.

Pan S, Sun Y, Sui D, Yang T, Fu S, Wang J, Hui B, Xi R, He C, Zhang X.

Biomed Pharmacother. 2018 Jun;102:567-574. doi: 10.1016/j.biopha.2018.03.109. Epub 2018 Apr 5.


Updated Results of Rituximab Pre- and Post-BEAM with or without 90Yttrium Ibritumomab Tiuxetan during Autologous Transplant for Diffuse Large B-cell Lymphoma.

Chahoud J, Sui D, Erwin WD, Gulbis AM, Korbling M, Zhang M, Ahmed S, Alatrash G, Anderlini P, Ciurea SO, Oran B, Fayad LE, Bassett RL Jr, Jabbour EJ, Medeiros LJ, Macapinlac HA, Young KH, Khouri IF.

Clin Cancer Res. 2018 May 15;24(10):2304-2311. doi: 10.1158/1078-0432.CCR-17-3561. Epub 2018 Feb 23.


Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method.

Wei Y, Yang L, Zhang X, Sui D, Wang C, Wang K, Shan M, Guo D, Wang H.

Drug Metab Dispos. 2018 May;46(5):525-531. doi: 10.1124/dmd.117.078444. Epub 2018 Feb 14.


20(S)-Protopanaxadiol induces apoptosis in human hepatoblastoma HepG2 cells by downregulating the protein kinase B signaling pathway.

Lu Z, Xu H, Yu X, Wang Y, Huang L, Jin X, Sui D.

Exp Ther Med. 2018 Feb;15(2):1277-1284. doi: 10.3892/etm.2017.5594. Epub 2017 Dec 5.


Ganglioside GM1 protects against high altitude cerebral edema in rats by suppressing the oxidative stress and inflammatory response via the PI3K/AKT-Nrf2 pathway.

Gong G, Yin L, Yuan L, Sui D, Sun Y, Fu H, Chen L, Wang X.

Mol Immunol. 2018 Mar;95:91-98. doi: 10.1016/j.molimm.2018.02.001. Epub 2018 Feb 20.


Impaired Functional Criticality of Human Brain during Alzheimer's Disease Progression.

Jiang L, Sui D, Qiao K, Dong HM, Chen L, Han Y.

Sci Rep. 2018 Jan 22;8(1):1324. doi: 10.1038/s41598-018-19674-7.


Atractylodes lancea rhizome water extract reduces triptolide-induced toxicity and enhances anti-inflammatory effects.

Wei Y, Sui DJ, Xu HM, Ouyang Z, Wu N, Wang DJ, Zhang XY, Qian DW.

Chin J Nat Med. 2017 Dec;15(12):905-911. doi: 10.1016/S1875-5364(18)30006-2.


Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats.

Jiang Y, Li M, Lu Z, Wang Y, Yu X, Sui D, Fu L.

Exp Ther Med. 2017 Nov;14(5):4977-4985. doi: 10.3892/etm.2017.5198. Epub 2017 Sep 22.


Hypolipidemic effects of total flavonoide extracted from the leaves of Actinidiakolomikta in rats fed a high-fat diet.

Yu Z, Xu H, Yu X, Sui D, Lin G.

Iran J Basic Med Sci. 2017 Oct;20(10):1141-1148. doi: 10.22038/IJBMS.2017.9365.


[Protective effects of five different types of Dendrobium on CCl4-induced liver injury in mice].

Wang K, Sui DJ, Wang CS, Yang L, Ouyang Z, Chen NF, Han BX, Wei Y.

Zhongguo Zhong Yao Za Zhi. 2017 May;42(10):1945-1950. doi: 10.19540/j.cnki.cjcmm.2017.0082. Chinese.


Cell death-inducing DFF45-like effector C gene silencing alleviates pulmonary vascular remodeling in a type 2 diabetic rat model.

Sui DX, Zhou HM, Wang F, Zhong M, Zhang W, Ti Y.

J Diabetes Investig. 2018 Jul;9(4):741-752. doi: 10.1111/jdi.12768. Epub 2017 Nov 28.


Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway.

Zhang T, Liu J, Fellner M, Zhang C, Sui D, Hu J.

Sci Adv. 2017 Aug 25;3(8):e1700344. doi: 10.1126/sciadv.1700344. eCollection 2017 Aug.


Ultrastaging of Sentinel Lymph Nodes in Endometrial Carcinoma According to Use of 2 Different Methods.

Euscher E, Sui D, Soliman P, Westin S, Ramalingam P, Bassett R, Malpica A.

Int J Gynecol Pathol. 2018 May;37(3):242-251. doi: 10.1097/PGP.0000000000000415.


Metformin ameliorates diabetic nephropathy in a rat model of low-dose streptozotocin-induced diabetes.

Zhang S, Xu H, Yu X, Wu Y, Sui D.

Exp Ther Med. 2017 Jul;14(1):383-390. doi: 10.3892/etm.2017.4475. Epub 2017 May 18.


Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes.

Fang S, Wang Y, Dang Y, Gagel A, Ross MI, Gershenwald JE, Cormier JN, Wargo J, Haydu LE, Davies MA, McQuade JL, Sui D, Bassett RL, Reveille JD, Wei Q, Amos CI, Lee JE.

J Invest Dermatol. 2017 Aug;137(8):1792-1795. doi: 10.1016/j.jid.2017.04.007. Epub 2017 Apr 23. No abstract available.


Effects of tetrahydroberberine and tetrahydropalmatine on hepatic cytochrome P450 expression and their toxicity in mice.

Wang D, Wang K, Sui D, Ouyang Z, Xu H, Wei Y.

Chem Biol Interact. 2017 Apr 25;268:47-52. doi: 10.1016/j.cbi.2017.02.019. Epub 2017 Feb 28.


Cancer type predicts alloimmunization following RhD-incompatible RBC transfusions.

Arora K, Kelley J, Sui D, Ning J, Martinez F, Lichtiger B, Tholpady A.

Transfusion. 2017 Apr;57(4):952-958. doi: 10.1111/trf.13999. Epub 2017 Feb 12.


The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing.

Liu A, Sui D, Wu D, Hu J.

Sci Adv. 2016 Nov 18;2(11):e1600925. doi: 10.1126/sciadv.1600925. eCollection 2016 Nov.


Ginsenoside Rg3 Improves Cardiac Function after Myocardial Ischemia/Reperfusion via Attenuating Apoptosis and Inflammation.

Zhang LP, Jiang YC, Yu XF, Xu HL, Li M, Zhao XZ, Sui DY.

Evid Based Complement Alternat Med. 2016;2016:6967853. doi: 10.1155/2016/6967853. Epub 2016 Dec 26.


Bendamustine added to allogeneic conditioning improves long-term outcomes in patients with CLL.

Khouri IF, Sui D, Jabbour EJ, Samuels BI, Turturro F, Alatrash G, Anderlini P, Ahmed S, Oran B, Ciurea SO, Marin D, Olson A, Patel KK, Popat UR, Ledesma C, Kadia TM, Ferrajoli A, Burger JA, Jorgensen JL, Medeiros LJ, Bassett RL, Gulbis AM.

Bone Marrow Transplant. 2017 Jan;52(1):28-33. doi: 10.1038/bmt.2016.204. Epub 2016 Sep 5.


Circulating tumor cell is a common property of brain glioma and promotes the monitoring system.

Gao F, Cui Y, Jiang H, Sui D, Wang Y, Jiang Z, Zhao J, Lin S.

Oncotarget. 2016 Nov 1;7(44):71330-71340. doi: 10.18632/oncotarget.11114.

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