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Items: 1 to 50 of 199

1.

Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns.

Menni C, McCallum L, Pietzner M, Zierer J, Aman A, Suhre K, Mohney RP, Mangino M, Friedrich N, Spector TD, Padmanabhan S.

Sci Rep. 2019 Oct 21;9(1):15088. doi: 10.1038/s41598-019-51492-3.

2.

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies.

Yee SW, Stecula A, Chien HC, Zou L, Feofanova EV, van Borselen M, Cheung KWK, Yousri NA, Suhre K, Kinchen JM, Boerwinkle E, Irannejad R, Yu B, Giacomini KM.

PLoS Genet. 2019 Sep 25;15(9):e1008208. doi: 10.1371/journal.pgen.1008208. eCollection 2019 Sep.

3.

Alterations in long noncoding RNAs in women with and without polycystic ovarian syndrome.

Butler AE, Hayat S, Dargham SR, Malek JA, Abdulla SA, Mohamoud YA, Suhre K, Sathyapalan T, Atkin SL.

Clin Endocrinol (Oxf). 2019 Sep 4. doi: 10.1111/cen.14087. [Epub ahead of print]

PMID:
31482638
4.

A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells.

Billing AM, Dib SS, Bhagwat AM, da Silva IT, Drummond RD, Hayat S, Al-Mismar R, Ben-Hamidane H, Goswami N, Engholm-Keller K, Larsen MR, Suhre K, Rafii A, Graumann J.

Mol Cell Proteomics. 2019 Oct;18(10):1950-1966. doi: 10.1074/mcp.RA119.001356. Epub 2019 Jul 22.

PMID:
31332097
5.

Association of childhood traumatization and neuropsychiatric outcomes with altered plasma micro RNA-levels.

Van der Auwera S, Ameling S, Wittfeld K, d'Harcourt Rowold E, Nauck M, Völzke H, Suhre K, Najafi-Shoushtari H, Methew J, Ramachandran V, Bülow R, Völker U, Grabe HJ.

Neuropsychopharmacology. 2019 Nov;44(12):2030-2037. doi: 10.1038/s41386-019-0460-2. Epub 2019 Jul 8.

PMID:
31284290
6.

Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome.

Suhre K, Trbojević-Akmačić I, Ugrina I, Mook-Kanamori DO, Spector T, Graumann J, Lauc G, Falchi M.

Metabolites. 2019 Jun 26;9(7). pii: E122. doi: 10.3390/metabo9070122.

7.

Novel subpopulations in date palm (Phoenix dactylifera) identified by population-wide organellar genome sequencing.

Mohamoud YA, Mathew LS, Torres MF, Younuskunju S, Krueger R, Suhre K, Malek JA.

BMC Genomics. 2019 Jun 17;20(1):498. doi: 10.1186/s12864-019-5834-7.

8.

Characterization of Bulk Phosphatidylcholine Compositions in Human Plasma Using Side-Chain Resolving Lipidomics.

Quell JD, Römisch-Margl W, Haid M, Krumsiek J, Skurk T, Halama A, Stephan N, Adamski J, Hauner H, Mook-Kanamori D, Mohney RP, Daniel H, Suhre K, Kastenmüller G.

Metabolites. 2019 Jun 8;9(6). pii: E109. doi: 10.3390/metabo9060109.

9.

Defining the genetic control of human blood plasma N-glycome using genome-wide association study.

Sharapov SZ, Tsepilov YA, Klaric L, Mangino M, Thareja G, Shadrina AS, Simurina M, Dagostino C, Dmitrieva J, Vilaj M, Vuckovic F, Pavic T, Stambuk J, Trbojevic-Akmacic I, Kristic J, Simunovic J, Momcilovic A, Campbell H, Doherty M, Dunlop MG, Farrington SM, Pucic-Bakovic M, Gieger C, Allegri M, Louis E, Georges M, Suhre K, Spector T, Williams FMK, Lauc G, Aulchenko YS.

Hum Mol Genet. 2019 Jun 15;28(12):2062-2077. doi: 10.1093/hmg/ddz054.

10.

The Saliva Metabolome in Association to Oral Health Status.

Liebsch C, Pitchika V, Pink C, Samietz S, Kastenmüller G, Artati A, Suhre K, Adamski J, Nauck M, Völzke H, Friedrich N, Kocher T, Holtfreter B, Pietzner M.

J Dent Res. 2019 Jun;98(6):642-651. doi: 10.1177/0022034519842853. Epub 2019 Apr 26.

PMID:
31026179
11.

Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population.

Yu B, Flexeder C, McGarrah RW 3rd, Wyss A, Morrison AC, North KE, Boerwinkle E, Kastenmüller G, Gieger C, Suhre K, Karrasch S, Peters A, Wagner GR, Michelotti GA, Mohney RP, Schulz H, London SJ.

Metabolites. 2019 Apr 1;9(4). pii: E61. doi: 10.3390/metabo9040061.

12.

Metabolic profiling of elite athletes with different cardiovascular demand.

Al-Khelaifi F, Donati F, Botrè F, Latiff A, Abraham D, Hingorani A, Georgakopoulos C, Suhre K, Yousri NA, Elrayess MA.

Scand J Med Sci Sports. 2019 Jul;29(7):933-943. doi: 10.1111/sms.13425. Epub 2019 Apr 29.

PMID:
30929282
13.

Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS.

Halama A, Aye MM, Dargham SR, Kulinski M, Suhre K, Atkin SL.

Front Endocrinol (Lausanne). 2019 Feb 27;10:116. doi: 10.3389/fendo.2019.00116. eCollection 2019.

14.

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies.

Do KT, Wahl S, Raffler J, Molnos S, Laimighofer M, Adamski J, Suhre K, Strauch K, Peters A, Gieger C, Langenberg C, Stewart ID, Theis FJ, Grallert H, Kastenmüller G, Krumsiek J.

Metabolomics. 2018 Sep 20;14(10):128. doi: 10.1007/s11306-018-1420-2.

15.

Metabolic and proteomic signatures of hypoglycaemia in type 2 diabetes.

Halama A, Kahal H, Bhagwat AM, Zierer J, Sathyapalan T, Graumann J, Suhre K, Atkin SL.

Diabetes Obes Metab. 2018 Dec 7. doi: 10.1111/dom.13602. [Epub ahead of print]

PMID:
30525282
16.

Genotyping-by-sequencing identifies date palm clone preference in agronomics of the State of Qatar.

Thareja G, Mathew S, Mathew LS, Mohamoud YA, Suhre K, Malek JA.

PLoS One. 2018 Dec 5;13(12):e0207299. doi: 10.1371/journal.pone.0207299. eCollection 2018.

17.

Author Correction: Genus-wide sequencing support a two-locus model for sex-determination in Phoenix.

Torres MF, Mathew LS, Ahmed I, Al-Azwani IK, Krueger R, Rivera-Nuñez D, Mohamoud YA, Clark AG, Suhre K, Malek JA.

Nat Commun. 2018 Dec 3;9(1):5219. doi: 10.1038/s41467-018-07742-5.

18.

Genus-wide sequencing supports a two-locus model for sex-determination in Phoenix.

Torres MF, Mathew LS, Ahmed I, Al-Azwani IK, Krueger R, Rivera-Nuñez D, Mohamoud YA, Clark AG, Suhre K, Malek JA.

Nat Commun. 2018 Sep 28;9(1):3969. doi: 10.1038/s41467-018-06375-y. Erratum in: Nat Commun. 2018 Dec 3;9(1):5219.

19.

Metabolomics profiling of xenobiotics in elite athletes: relevance to supplement consumption.

Al-Khelaifi F, Diboun I, Donati F, Botrè F, Alsayrafi M, Georgakopoulos C, Yousri NA, Suhre K, Elrayess MA.

J Int Soc Sports Nutr. 2018 Sep 27;15(1):48. doi: 10.1186/s12970-018-0254-7.

20.

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci.

Stacey D, Fauman EB, Ziemek D, Sun BB, Harshfield EL, Wood AM, Butterworth AS, Suhre K, Paul DS.

Nucleic Acids Res. 2019 Jan 10;47(1):e3. doi: 10.1093/nar/gky837.

21.

Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D.

Nat Commun. 2018 Sep 18;9(1):3853. doi: 10.1038/s41467-018-06231-z.

22.

Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D.

Nat Commun. 2018 Aug 15;9(1):3268. doi: 10.1038/s41467-018-05512-x. Erratum in: Nat Commun. 2018 Sep 18;9(1):3853.

23.

Ldlr-/- and ApoE-/- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease.

Saulnier-Blache JS, Wilson R, Klavins K, Graham D, Alesutan I, Kastenmüller G, Wang-Sattler R, Adamski J, Roden M, Rathmann W, Seissler J, Meisinger C, Koenig W, Thiery J, Suhre K, Peters A, Kuro-O M, Lang F, Dallmann G, Delles C, Voelkl J, Waldenberger M, Bascands JL, Klein J, Schanstra JP.

Atherosclerosis. 2018 Sep;276:140-147. doi: 10.1016/j.atherosclerosis.2018.07.024. Epub 2018 Jul 21.

PMID:
30059845
24.

MoDentify: phenotype-driven module identification in metabolomics networks at different resolutions.

Do KT, Rasp DJN, Kastenmüller G, Suhre K, Krumsiek J.

Bioinformatics. 2019 Feb 1;35(3):532-534. doi: 10.1093/bioinformatics/bty650.

25.

A comprehensive metabolomic data set of date palm fruit.

Stephan N, Halama A, Mathew S, Hayat S, Bhagwat A, Mathew LS, Diboun I, Malek J, Suhre K.

Data Brief. 2018 Apr 10;18:1313-1321. doi: 10.1016/j.dib.2018.04.012. eCollection 2018 Jun.

26.

Genomic atlas of the human plasma proteome.

Sun BB, Maranville JC, Peters JE, Stacey D, Staley JR, Blackshaw J, Burgess S, Jiang T, Paige E, Surendran P, Oliver-Williams C, Kamat MA, Prins BP, Wilcox SK, Zimmerman ES, Chi A, Bansal N, Spain SL, Wood AM, Morrell NW, Bradley JR, Janjic N, Roberts DJ, Ouwehand WH, Todd JA, Soranzo N, Suhre K, Paul DS, Fox CS, Plenge RM, Danesh J, Runz H, Butterworth AS.

Nature. 2018 Jun;558(7708):73-79. doi: 10.1038/s41586-018-0175-2. Epub 2018 Jun 6.

27.

Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis.

Halama A, Kulinski M, Dib SS, Zaghlool SB, Siveen KS, Iskandarani A, Zierer J, Prabhu KS, Satheesh NJ, Bhagwat AM, Uddin S, Kastenmüller G, Elemento O, Gross SS, Suhre K.

Cancer Lett. 2018 Aug 28;430:133-147. doi: 10.1016/j.canlet.2018.05.017. Epub 2018 May 17.

28.

Single nucleotide variant counts computed from RNA sequencing and cellular traffic into human kidney allografts.

Thareja G, Yang H, Hayat S, Mueller FB, Lee JR, Lubetzky M, Dadhania DM, Belkadi A, Seshan SV, Suhre K, Suthanthiran M, Muthukumar T.

Am J Transplant. 2018 Oct;18(10):2429-2442. doi: 10.1111/ajt.14870. Epub 2018 May 15.

29.

Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population.

Yousri NA, Fakhro KA, Robay A, Rodriguez-Flores JL, Mohney RP, Zeriri H, Odeh T, Kader SA, Aldous EK, Thareja G, Kumar M, Al-Shakaki A, Chidiac OM, Mohamoud YA, Mezey JG, Malek JA, Crystal RG, Suhre K.

Nat Commun. 2018 Jan 23;9(1):333. doi: 10.1038/s41467-017-01972-9.

30.

Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.

Zaghlool SB, Mook-Kanamori DO, Kader S, Stephan N, Halama A, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Roemisch-Margl W, Adamski J, Kastenmüller G, Friedrich N, Visconti A, Tsai PC, Spector T, Bell JT, Falchi M, Wahl A, Waldenberger M, Peters A, Gieger C, Pezer M, Lauc G, Graumann J, Malek JA, Suhre K.

Hum Mol Genet. 2018 Mar 15;27(6):1106-1121. doi: 10.1093/hmg/ddy006.

31.

A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines.

Al-Khelaifi F, Diboun I, Donati F, Botrè F, Alsayrafi M, Georgakopoulos C, Suhre K, Yousri NA, Elrayess MA.

Sports Med Open. 2018 Jan 5;4(1):2. doi: 10.1186/s40798-017-0114-z.

32.

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.

Sekula P, Dettmer K, Vogl FC, Gronwald W, Ellmann L, Mohney RP, Eckardt KU, Suhre K, Kastenmüller G, Oefner PJ, Köttgen A.

Sci Rep. 2017 Dec 12;7(1):17400. doi: 10.1038/s41598-017-17107-5.

33.

Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives.

Hertel J, König J, Homuth G, Van der Auwera S, Wittfeld K, Pietzner M, Kacprowski T, Pfeiffer L, Kretschmer A, Waldenberger M, Kastenmüller G, Artati A, Suhre K, Adamski J, Langner S, Völker U, Völzke H, Nauck M, Friedrich N, Grabe HJ.

Sci Rep. 2017 Oct 26;7(1):14111. doi: 10.1038/s41598-017-13927-7.

34.

pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms.

Molnos S, Baumbach C, Wahl S, Müller-Nurasyid M, Strauch K, Wang-Sattler R, Waldenberger M, Meitinger T, Adamski J, Kastenmüller G, Suhre K, Peters A, Grallert H, Theis FJ, Gieger C.

BMC Bioinformatics. 2017 Sep 29;18(1):429. doi: 10.1186/s12859-017-1838-y.

35.

Phenotype-driven identification of modules in a hierarchical map of multifluid metabolic correlations.

Do KT, Pietzner M, Rasp DJ, Friedrich N, Nauck M, Kocher T, Suhre K, Mook-Kanamori DO, Kastenmüller G, Krumsiek J.

NPJ Syst Biol Appl. 2017 Sep 21;3:28. doi: 10.1038/s41540-017-0029-9. eCollection 2017.

36.

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.

Molnos S, Wahl S, Haid M, Eekhoff EMW, Pool R, Floegel A, Deelen J, Much D, Prehn C, Breier M, Draisma HH, van Leeuwen N, Simonis-Bik AMC, Jonsson A, Willemsen G, Bernigau W, Wang-Sattler R, Suhre K, Peters A, Thorand B, Herder C, Rathmann W, Roden M, Gieger C, Kramer MHH, van Heemst D, Pedersen HK, Gudmundsdottir V, Schulze MB, Pischon T, de Geus EJC, Boeing H, Boomsma DI, Ziegler AG, Slagboom PE, Hummel S, Beekman M, Grallert H, Brunak S, McCarthy MI, Gupta R, Pearson ER, Adamski J, 't Hart LM.

Diabetologia. 2018 Jan;61(1):117-129. doi: 10.1007/s00125-017-4436-7. Epub 2017 Oct 25.

37.

Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis.

Yousri NA, Bayoumy K, Elhaq WG, Mohney RP, Emadi SA, Hammoudeh M, Halabi H, Masri B, Badsha H, Uthman I, Plenge R, Saxena R, Suhre K, Arayssi T.

Sci Rep. 2017 Aug 22;7(1):9137. doi: 10.1038/s41598-017-05439-1.

38.

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.

Jäger S, Wahl S, Kröger J, Sharma S, Hoffmann P, Floegel A, Pischon T, Prehn C, Adamski J, Müller-Nurasyid M, Waldenberger M, Strauch K, Peters A, Gieger C, Suhre K, Grallert H, Boeing H, Schulze MB, Meidtner K.

Sci Rep. 2017 Jul 20;7(1):6037. doi: 10.1038/s41598-017-06158-3.

39.

The association between various smoking behaviors, cotinine biomarkers and skin autofluorescence, a marker for advanced glycation end product accumulation.

van Waateringe RP, Mook-Kanamori MJ, Slagter SN, van der Klauw MM, van Vliet-Ostaptchouk JV, Graaff R, Lutgers HL, Suhre K, El-Din Selim MM, Mook-Kanamori DO, Wolffenbuttel BHR.

PLoS One. 2017 Jun 20;12(6):e0179330. doi: 10.1371/journal.pone.0179330. eCollection 2017.

40.

Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabetes.

Piontek U, Wallaschofski H, Kastenmüller G, Suhre K, Völzke H, Do KT, Artati A, Nauck M, Adamski J, Friedrich N, Pietzner M.

Sci Rep. 2017 May 22;7(1):2235. doi: 10.1038/s41598-017-02367-y.

41.

Response to Comment on Adam et al. Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes 2016;65:3776-3785.

Adam J, Brandmaier S, Troll M, Rotter M, Mohney RP, Heier M, Adamski J, Li Y, Neschen S, Kastenmüller G, Suhre K, Ankerst D, Meitinger T, Wang-Sattler R.

Diabetes. 2017 May;66(5):e3-e4. doi: 10.2337/dbi17-0010. No abstract available.

42.

Advanced glycation end products among patients maintained on antipsychotics.

Hammoudeh S, Ghuloum S, Mahfoud Z, Yehya A, Mook-Kanamori D, Mook-Kanamori M, Suhre K, Abdulhakam A, Al-Mujalli A, Hani Y, El Sherbiny R, Al-Amin H.

Int Clin Psychopharmacol. 2017 Sep;32(5):256-261. doi: 10.1097/YIC.0000000000000179.

PMID:
28492411
43.

Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome.

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J.

Nat Commun. 2017 Apr 11;8:15345. doi: 10.1038/ncomms15345. No abstract available.

44.

Metabolic network failures in Alzheimer's disease: A biochemical road map.

Toledo JB, Arnold M, Kastenmüller G, Chang R, Baillie RA, Han X, Thambisetty M, Tenenbaum JD, Suhre K, Thompson JW, John-Williams LS, MahmoudianDehkordi S, Rotroff DM, Jack JR, Motsinger-Reif A, Risacher SL, Blach C, Lucas JE, Massaro T, Louie G, Zhu H, Dallmann G, Klavins K, Koal T, Kim S, Nho K, Shen L, Casanova R, Varma S, Legido-Quigley C, Moseley MA, Zhu K, Henrion MYR, van der Lee SJ, Harms AC, Demirkan A, Hankemeier T, van Duijn CM, Trojanowski JQ, Shaw LM, Saykin AJ, Weiner MW, Doraiswamy PM, Kaddurah-Daouk R; Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium.

Alzheimers Dement. 2017 Sep;13(9):965-984. doi: 10.1016/j.jalz.2017.01.020. Epub 2017 Mar 22.

45.

Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers.

Ward-Caviness CK, Xu T, Aspelund T, Thorand B, Montrone C, Meisinger C, Dunger-Kaltenbach I, Zierer A, Yu Z, Helgadottir IR, Harris TB, Launer LJ, Ganna A, Lind L, Eiriksdottir G, Waldenberger M, Prehn C, Suhre K, Illig T, Adamski J, Ruepp A, Koenig W, Gudnason V, Emilsson V, Wang-Sattler R, Peters A.

Heart. 2017 Aug;103(16):1278-1285. doi: 10.1136/heartjnl-2016-310789. Epub 2017 Mar 2.

46.

Connecting genetic risk to disease end points through the human blood plasma proteome.

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J.

Nat Commun. 2017 Feb 27;8:14357. doi: 10.1038/ncomms14357.

47.

PopPAnTe: population and pedigree association testing for quantitative data.

Visconti A, Al-Shafai M, Al Muftah WA, Zaghlool SB, Mangino M, Suhre K, Falchi M.

BMC Genomics. 2017 Feb 10;18(1):150. doi: 10.1186/s12864-017-3527-7.

48.

Nesting of colon and ovarian cancer cells in the endothelial niche is associated with alterations in glycan and lipid metabolism.

Halama A, Guerrouahen BS, Pasquier J, Satheesh NJ, Suhre K, Rafii A.

Sci Rep. 2017 Jan 4;7:39999. doi: 10.1038/srep39999.

49.

Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects.

Zaghlool SB, Al-Shafai M, Al Muftah WA, Kumar P, Gieger C, Waldenberger M, Falchi M, Suhre K.

Clin Epigenetics. 2016 Nov 22;8:124. eCollection 2016.

50.

Mutation in noncoding RNA RNU12 causes early onset cerebellar ataxia.

Elsaid MF, Chalhoub N, Ben-Omran T, Kumar P, Kamel H, Ibrahim K, Mohamoud Y, Al-Dous E, Al-Azwani I, Malek JA, Suhre K, Ross ME, Aleem AA.

Ann Neurol. 2017 Jan;81(1):68-78. doi: 10.1002/ana.24826.

PMID:
27863452

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