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Items: 1 to 50 of 70

1.

Multidimensional Fluorescence Microscopy for Simultaneous Functional and Structural Imaging.

Suhling K.

Biophys J. 2019 May 21;116(10):1787-1789. doi: 10.1016/j.bpj.2019.04.016. Epub 2019 Apr 22. No abstract available.

PMID:
31053256
2.

Targeted fluorescence lifetime probes reveal responsive organelle viscosity and membrane fluidity.

Steinmark IE, James AL, Chung PH, Morton PE, Parsons M, Dreiss CA, Lorenz CD, Yahioglu G, Suhling K.

PLoS One. 2019 Feb 14;14(2):e0211165. doi: 10.1371/journal.pone.0211165. eCollection 2019.

3.

PRODAN differentially influences its local environment.

Suhaj A, Le Marois A, Williamson DJ, Suhling K, Lorenz CD, Owen DM.

Phys Chem Chem Phys. 2018 Jun 13;20(23):16060-16066. doi: 10.1039/c8cp00543e.

PMID:
29850681
4.

Quantitative Live Cell FLIM Imaging in Three Dimensions.

Le Marois A, Suhling K.

Adv Exp Med Biol. 2017;1035:31-48. doi: 10.1007/978-3-319-67358-5_3. Review.

PMID:
29080129
5.

TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p.

Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S, Gomez JE, Hu X, Hurst C, Hall T, Umamaheswaran S, Wesley L, Gagea M, Shires M, Manfield I, Knowles MA, Davies S, Suhling K, Gonzalez YT, Carragher N, Macleod K, Abbott NJ, Calin GA, Gamper N, Zygmunt PM, Timsah Z.

Nat Commun. 2017 Oct 16;8(1):947. doi: 10.1038/s41467-017-00983-w.

6.

Spontaneous emission in non-local materials.

Ginzburg P, Roth DJ, Nasir ME, Segovia P, Krasavin AV, Levitt J, Hirvonen LM, Wells B, Suhling K, Richards D, Podolskiy VA, Zayats AV.

Light Sci Appl. 2017 Jun 2;6(6):e16273. doi: 10.1038/lsa.2016.273. eCollection 2017 Jun.

7.

Determining a fluorophore's transition dipole moment from fluorescence lifetime measurements in solvents of varying refractive index.

Chung PH, Tregidgo C, Suhling K.

Methods Appl Fluoresc. 2016 Nov 11;4(4):045001. doi: 10.1088/2050-6120/4/4/045001.

PMID:
28192304
8.

Nanoscale diffusion in the synaptic cleft and beyond measured with time-resolved fluorescence anisotropy imaging.

Zheng K, Jensen TP, Savtchenko LP, Levitt JA, Suhling K, Rusakov DA.

Sci Rep. 2017 Feb 9;7:42022. doi: 10.1038/srep42022.

9.

Photon counting phosphorescence lifetime imaging with TimepixCam.

Hirvonen LM, Fisher-Levine M, Suhling K, Nomerotski A.

Rev Sci Instrum. 2017 Jan;88(1):013104. doi: 10.1063/1.4973717.

PMID:
28147700
10.

Noise-Corrected Principal Component Analysis of fluorescence lifetime imaging data.

Le Marois A, Labouesse S, Suhling K, Heintzmann R.

J Biophotonics. 2017 Sep;10(9):1124-1133. doi: 10.1002/jbio.201600160. Epub 2016 Dec 12.

PMID:
27943625
11.

A wide-field TCSPC FLIM system based on an MCP PMT with a delay-line anode.

Becker W, Hirvonen LM, Milnes J, Conneely T, Jagutzki O, Netz H, Smietana S, Suhling K.

Rev Sci Instrum. 2016 Sep;87(9):093710.

PMID:
27782585
12.

Twist and Probe-Fluorescent Molecular Rotors Image Escherichia coli Cell Membrane Viscosity.

Suhling K.

Biophys J. 2016 Oct 4;111(7):1337-1338. doi: 10.1016/j.bpj.2016.08.021. No abstract available.

13.

In vivo biodistribution studies and ex vivo lymph node imaging using heavy metal-free quantum dots.

Yaghini E, Turner HD, Le Marois AM, Suhling K, Naasani I, MacRobert AJ.

Biomaterials. 2016 Oct;104:182-91. doi: 10.1016/j.biomaterials.2016.07.014. Epub 2016 Jul 12.

14.

Photon counting imaging and centroiding with an electron-bombarded CCD using single molecule localisation software.

Hirvonen LM, Barber MJ, Suhling K.

Nucl Instrum Methods Phys Res A. 2016 Jun 1;820:121-125.

15.

Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy.

Hirvonen LM, Fruhwirth GO, Srikantha N, Barber MJ, Neffendorf JE, Suhling K, Jackson TL.

Pharm Res. 2016 Aug;33(8):2025-32. doi: 10.1007/s11095-016-1940-2. Epub 2016 May 25.

16.

Photon Counting Imaging with an Electron-Bombarded Pixel Image Sensor.

Hirvonen LM, Suhling K.

Sensors (Basel). 2016 Apr 28;16(5). pii: E617. doi: 10.3390/s16050617. Review.

17.

Molecular rheology of neuronal membranes explored using a molecular rotor: Implications for receptor function.

Pal S, Chakraborty H, Bandari S, Yahioglu G, Suhling K, Chattopadhyay A.

Chem Phys Lipids. 2016 Mar;196:69-75. doi: 10.1016/j.chemphyslip.2016.02.004. Epub 2016 Feb 12.

PMID:
26879380
18.

Simultaneous FRAP, FLIM and FAIM for measurements of protein mobility and interaction in living cells.

Levitt JA, Morton PE, Fruhwirth GO, Santis G, Chung PH, Parsons M, Suhling K.

Biomed Opt Express. 2015 Sep 8;6(10):3842-54. doi: 10.1364/BOE.6.003842. eCollection 2015 Oct 1.

19.

The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy.

Shivalingam A, Izquierdo MA, Marois AL, Vyšniauskas A, Suhling K, Kuimova MK, Vilar R.

Nat Commun. 2015 Sep 9;6:8178. doi: 10.1038/ncomms9178.

20.

Spectrally resolved fluorescence lifetime imaging of Nile red for measurements of intracellular polarity.

Levitt JA, Chung PH, Suhling K.

J Biomed Opt. 2015 Sep;20(9):096002. doi: 10.1117/1.JBO.20.9.096002.

PMID:
26334975
21.

Single-molecule localization software applied to photon counting imaging.

Hirvonen LM, Kilfeather T, Suhling K.

Appl Opt. 2015 Jun 1;54(16):5074-82. doi: 10.1364/AO.54.005074.

PMID:
26192667
22.

Genetically encoded sensors of protein hydrodynamics and molecular proximity.

Hoepker AC, Wang A, Le Marois A, Suhling K, Yan Y, Marriott G.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2569-74. doi: 10.1073/pnas.1424021112. Epub 2015 Apr 30.

23.

A high speed multifocal multiphoton fluorescence lifetime imaging microscope for live-cell FRET imaging.

Poland SP, Krstajić N, Monypenny J, Coelho S, Tyndall D, Walker RJ, Devauges V, Richardson J, Dutton N, Barber P, Li DD, Suhling K, Ng T, Henderson RK, Ameer-Beg SM.

Biomed Opt Express. 2015 Jan 6;6(2):277-96. doi: 10.1364/BOE.6.000277. eCollection 2015 Feb 1.

24.

Photon counting imaging with an electron-bombarded CCD: towards a parallel-processing photoelectronic time-to-amplitude converter.

Hirvonen LM, Jiggins S, Sergent N, Zanda G, Suhling K.

Rev Sci Instrum. 2014 Dec;85(12):123102. doi: 10.1063/1.4901935.

PMID:
25554267
25.

Time-resolved multifocal multiphoton microscope for high speed FRET imaging in vivo.

Poland SP, Krstajić N, Coelho S, Tyndall D, Walker RJ, Devauges V, Morton PE, Nicholas NS, Richardson J, Li DD, Suhling K, Wells CM, Parsons M, Henderson RK, Ameer-Beg SM.

Opt Lett. 2014 Oct 15;39(20):6013-6. doi: 10.1364/OL.39.006013.

26.

Wide-field time-correlated single-photon counting (TCSPC) lifetime microscopy with microsecond time resolution.

Hirvonen LM, Festy F, Suhling K.

Opt Lett. 2014 Oct 1;39(19):5602-5. doi: 10.1364/OL.39.005602.

PMID:
25360938
27.

Gd-containing conjugated polymer nanoparticles: bimodal nanoparticles for fluorescence and MRI imaging.

Hashim Z, Green M, Chung PH, Suhling K, Protti A, Phinikaridou A, Botnar R, Khanbeigi RA, Thanou M, Dailey LA, Commander NJ, Rowland C, Scott J, Jenner D.

Nanoscale. 2014 Jul 21;6(14):8376-86. doi: 10.1039/c4nr01491j.

PMID:
24941427
28.

Fixed pattern noise in localization microscopy.

Fox-Roberts P, Wen T, Suhling K, Cox S.

Chemphyschem. 2014 Mar 17;15(4):677-86. doi: 10.1002/cphc.201300756. Epub 2014 Jan 31.

PMID:
24482113
29.

Time-resolved fluorescence anisotropy imaging.

Suhling K, Levitt J, Chung PH.

Methods Mol Biol. 2014;1076:503-19. doi: 10.1007/978-1-62703-649-8_22.

PMID:
24108641
30.

Fluorescence lifetime imaging and FRET-induced intracellular redistribution of Tat-conjugated quantum dot nanoparticles through interaction with a phthalocyanine photosensitiser.

Yaghini E, Giuntini F, Eggleston IM, Suhling K, Seifalian AM, MacRobert AJ.

Small. 2014 Feb 26;10(4):782-92. doi: 10.1002/smll.201301459. Epub 2013 Sep 13.

PMID:
24031023
31.

Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity.

Ahmed Z, Lin CC, Suen KM, Melo FA, Levitt JA, Suhling K, Ladbury JE.

J Cell Biol. 2013 Feb 18;200(4):493-504. doi: 10.1083/jcb.201204106.

32.

Biosynthesis of luminescent quantum dots in an earthworm.

Stürzenbaum SR, Höckner M, Panneerselvam A, Levitt J, Bouillard JS, Taniguchi S, Dailey LA, Ahmad Khanbeigi R, Rosca EV, Thanou M, Suhling K, Zayats AV, Green M.

Nat Nanotechnol. 2013 Jan;8(1):57-60. doi: 10.1038/nnano.2012.232. Epub 2012 Dec 23.

PMID:
23263722
33.

Luminescence lifetimes of neutral nitrogen-vacancy centres in synthetic diamond containing nitrogen.

Liaugaudas G, Davies G, Suhling K, Khan RU, Evans DJ.

J Phys Condens Matter. 2012 Oct 31;24(43):435503. doi: 10.1088/0953-8984/24/43/435503. Epub 2012 Oct 3.

PMID:
23032562
34.

Homodimerization of amyloid precursor protein at the plasma membrane: a homoFRET study by time-resolved fluorescence anisotropy imaging.

Devauges V, Marquer C, Lécart S, Cossec JC, Potier MC, Fort E, Suhling K, Lévêque-Fort S.

PLoS One. 2012;7(9):e44434. doi: 10.1371/journal.pone.0044434. Epub 2012 Sep 4.

35.

Influence of molecular shape, conformability, net surface charge, and tissue interaction on transscleral macromolecular diffusion.

Srikantha N, Mourad F, Suhling K, Elsaid N, Levitt J, Chung PH, Somavarapu S, Jackson TL.

Exp Eye Res. 2012 Sep;102:85-92. doi: 10.1016/j.exer.2012.07.007. Epub 2012 Jul 27.

PMID:
22846670
36.

A fluorescent biosensor reveals conformational changes in human immunoglobulin E Fc: implications for mechanisms of receptor binding, inhibition, and allergen recognition.

Hunt J, Keeble AH, Dale RE, Corbett MK, Beavil RL, Levitt J, Swann MJ, Suhling K, Ameer-Beg S, Sutton BJ, Beavil AJ.

J Biol Chem. 2012 May 18;287(21):17459-70. doi: 10.1074/jbc.M111.331967. Epub 2012 Mar 22.

37.

Fluorescence lifetime imaging of molecular rotors in living cells.

Suhling K, Levitt JA, Chung PH, Kuimova MK, Yahioglu G.

J Vis Exp. 2012 Feb 9;(60). pii: 2925. doi: 10.3791/2925.

38.

A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse.

Carlin LM, Evans R, Milewicz H, Fernandes L, Matthews DR, Perani M, Levitt J, Keppler MD, Monypenny J, Coolen T, Barber PR, Vojnovic B, Suhling K, Fraternali F, Ameer-Beg S, Parker PJ, Thomas NS, Ng T.

Sci Signal. 2011 Nov 29;4(201):ra81. doi: 10.1126/scisignal.2001729.

39.

Fluorescence anisotropy of molecular rotors.

Levitt JA, Chung PH, Kuimova MK, Yahioglu G, Wang Y, Qu J, Suhling K.

Chemphyschem. 2011 Feb 25;12(3):662-72. doi: 10.1002/cphc.201000782. Epub 2011 Feb 15.

PMID:
21328515
40.

Rapid wide-field photon counting imaging with microsecond time resolution.

Suhling K, Sergent N, Levitt J, Green M.

Opt Express. 2010 Nov 22;18(24):25292-8. doi: 10.1364/OE.18.025292.

PMID:
21164877
41.

Photon arrival timing with sub-camera exposure time resolution in wide-field time-resolved photon counting imaging.

Petrášek Z, Suhling K.

Opt Express. 2010 Nov 22;18(24):24888-901. doi: 10.1364/OE.18.024888.

PMID:
21164834
42.

Phospholipid encapsulated semiconducting polymer nanoparticles: their use in cell imaging and protein attachment.

Howes P, Green M, Levitt J, Suhling K, Hughes M.

J Am Chem Soc. 2010 Mar 24;132(11):3989-96. doi: 10.1021/ja1002179.

PMID:
20175539
43.

Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function.

Ahmed Z, George R, Lin CC, Suen KM, Levitt JA, Suhling K, Ladbury JE.

Cell Signal. 2010 Jan;22(1):23-33. doi: 10.1016/j.cellsig.2009.08.011. Epub 2009 Sep 6.

PMID:
19735729
44.

Luminescence-lifetime mapping in diamond.

Liaugaudas G, Collins AT, Suhling K, Davies G, Heintzmann R.

J Phys Condens Matter. 2009 Sep 9;21(36):364210. doi: 10.1088/0953-8984/21/36/364210. Epub 2009 Aug 19.

PMID:
21832316
45.

Monitoring sol-to-gel transitions via fluorescence lifetime determination using viscosity sensitive fluorescent probes.

Hungerford G, Allison A, McLoskey D, Kuimova MK, Yahioglu G, Suhling K.

J Phys Chem B. 2009 Sep 3;113(35):12067-74. doi: 10.1021/jp902727y.

PMID:
19708714
46.

Imaging intracellular viscosity of a single cell during photoinduced cell death.

Kuimova MK, Botchway SW, Parker AW, Balaz M, Collins HA, Anderson HL, Suhling K, Ogilby PR.

Nat Chem. 2009 Apr;1(1):69-73. doi: 10.1038/nchem.120. Epub 2009 Mar 15.

47.

Fluorescence lifetime and polarization-resolved imaging in cell biology.

Levitt JA, Matthews DR, Ameer-Beg SM, Suhling K.

Curr Opin Biotechnol. 2009 Feb;20(1):28-36. doi: 10.1016/j.copbio.2009.01.004. Epub 2009 Mar 4. Review.

PMID:
19268568
48.

Photophysical properties and intracellular imaging of water-soluble porphyrin dimers for two-photon excited photodynamic therapy.

Kuimova MK, Collins HA, Balaz M, Dahlstedt E, Levitt JA, Sergent N, Suhling K, Drobizhev M, Makarov NS, Rebane A, Anderson HL, Phillips D.

Org Biomol Chem. 2009 Mar 7;7(5):889-96. doi: 10.1039/b814791d. Epub 2009 Jan 9.

49.

A complex of Shc and Ran-GTPase localises to the cell nucleus.

George R, Chan HL, Ahmed Z, Suen KM, Stevens CN, Levitt JA, Suhling K, Timms J, Ladbury JE.

Cell Mol Life Sci. 2009 Feb;66(4):711-20. doi: 10.1007/s00018-009-8667-8.

PMID:
19153664
50.

Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2).

Schüller AC, Ahmed Z, Levitt JA, Suen KM, Suhling K, Ladbury JE.

Biochem J. 2008 Dec 1;416(2):189-99. doi: 10.1042/BJ20080887.

PMID:
18840094

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