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Items: 1 to 50 of 277

1.

Association of Immune-Related Adverse Events with Pembrolizumab Efficacy in the Treatment of Advanced Urothelial Carcinoma.

Kobayashi K, Suzuki K, Hiraide M, Aoyama T, Yokokawa T, Shikibu S, Hashimoto K, Iikura Y, Sato H, Sugiyama E, Tajima M, Hama T.

Oncology. 2020 Jan 14:1-6. doi: 10.1159/000505340. [Epub ahead of print]

PMID:
31935736
2.

In situ imaging of monoamine localization and dynamics.

Sugiyama E, Skelly AN, Suematsu M, Sugiura Y.

Pharmacol Ther. 2020 Jan 10:107478. doi: 10.1016/j.pharmthera.2020.107478. [Epub ahead of print] Review.

PMID:
31931099
3.

Bioanalytical methods for therapeutic monoclonal antibodies and antibody-drug conjugates: A review of recent advances and future perspectives.

Todoroki K, Mizuno H, Sugiyama E, Toyo'oka T.

J Pharm Biomed Anal. 2020 Feb 5;179:112991. doi: 10.1016/j.jpba.2019.112991. Epub 2019 Nov 14. Review.

PMID:
31761377
4.

Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging.

Sugiyama E, Guerrini MM, Honda K, Hattori Y, Abe M, Källback P, Andrén PE, Tanaka KF, Setou M, Fagarasan S, Suematsu M, Sugiura Y.

iScience. 2019 Oct 25;20:359-372. doi: 10.1016/j.isci.2019.09.036. Epub 2019 Sep 27.

5.

Multiple External Root Resorption of Teeth as a New Manifestation of Systemic Sclerosis-A Cross-Sectional Study in Japan.

Memida T, Matsuda S, Kajiya M, Mizuno N, Ouhara K, Fujita T, Hirata S, Yoshida Y, Sugimoto T, Nishi H, Kawaguchi H, Sugiyama E, Kurihara H.

J Clin Med. 2019 Oct 4;8(10). pii: E1628. doi: 10.3390/jcm8101628.

6.

A Multicenter Prospective Study of the Efficacy and Safety of Combined Immunosuppressive Therapy with High-Dose Glucocorticoid, Tacrolimus, and Cyclophosphamide in Interstitial Lung Diseases Accompanied by Anti-Melanoma Differentiation-Associated Gene 5-Positive Dermatomyositis.

Tsuji H, Nakashima R, Hosono Y, Imura Y, Yagita M, Yoshifuji H, Hirata S, Nojima T, Sugiyama E, Hatta K, Taguchi Y, Katayama M, Tanizawa K, Handa T, Uozumi R, Akizuki S, Murakami K, Hashimoto M, Tanaka M, Ohmura K, Mimori T.

Arthritis Rheumatol. 2019 Sep 16. doi: 10.1002/art.41105. [Epub ahead of print]

PMID:
31524333
7.

Large-vessel vasculitis associated with PEGylated granulocyte-colony stimulating factor.

Yukawa K, Mokuda S, Yoshida Y, Hirata S, Sugiyama E.

Neth J Med. 2019 Aug;77(6):224-226.

8.

Non-small Cell Lung Cancer Treated by an Anti-programmed Cell Death-1 Antibody without a Flare-up of Preexisting Granulomatosis with Polyangiitis.

Yamada T, Masuda T, Yamaguchi K, Sakamoto S, Horimasu Y, Miyamoto S, Nakashima T, Iwamoto H, Hirata S, Fujitaka K, Hamada H, Sugiyama E, Hattori N.

Intern Med. 2019 Nov 1;58(21):3129-3132. doi: 10.2169/internalmedicine.3018-19. Epub 2019 Jul 10.

9.

Mechanical allodynia induced by optogenetic sensory nerve excitation activates dopamine signaling and metabolism in medial nucleus accumbens.

Sugiyama E, Kondo T, Kuzumaki N, Honda K, Yamanaka A, Narita M, Suematsu M, Sugiura Y.

Neurochem Int. 2019 Oct;129:104494. doi: 10.1016/j.neuint.2019.104494. Epub 2019 Jun 21.

10.

Tandem Mass Spectrometry Imaging Reveals Distinct Accumulation Patterns of Steroid Structural Isomers in Human Adrenal Glands.

Takeo E, Sugiura Y, Uemura T, Nishimoto K, Yasuda M, Sugiyama E, Ohtsuki S, Higashi T, Nishikawa T, Suematsu M, Fukusaki E, Shimma S.

Anal Chem. 2019 Jul 16;91(14):8918-8925. doi: 10.1021/acs.analchem.9b00619. Epub 2019 Jun 26.

PMID:
31204806
11.

Wwp2 maintains cartilage homeostasis through regulation of Adamts5.

Mokuda S, Nakamichi R, Matsuzaki T, Ito Y, Sato T, Miyata K, Inui M, Olmer M, Sugiyama E, Lotz M, Asahara H.

Nat Commun. 2019 Jun 3;10(1):2429. doi: 10.1038/s41467-019-10177-1.

12.

Association of olfactory impairment with indexes of sarcopenia and frailty in community-dwelling older adults.

Harita M, Miwa T, Shiga H, Yamada K, Sugiyama E, Okabe Y, Miyake Y, Okuno T, Iritani O, Morimoto S.

Geriatr Gerontol Int. 2019 May;19(5):384-391. doi: 10.1111/ggi.13621. Epub 2019 Apr 9.

PMID:
30968523
13.

Structural significance of residues 158-160 in the H3N2 hemagglutnin globular head: A computational study with implications in viral evolution and infection.

Cueno ME, Shiotsu H, Nakano K, Sugiyama E, Kikuta M, Usui R, Oya R, Imai K.

J Mol Graph Model. 2019 Jun;89:33-40. doi: 10.1016/j.jmgm.2019.02.007. Epub 2019 Feb 25.

PMID:
30849718
14.

A thin layer of sucrose octasulfate protects the oesophageal mucosal epithelium in reflux oesophagitis.

Hayakawa T, Kawasaki S, Hirayama Y, Tsutsui T, Sugiyama E, Adachi K, Kon R, Suematsu M, Sugiura Y.

Sci Rep. 2019 Mar 5;9(1):3559. doi: 10.1038/s41598-019-39087-4.

15.

Association of Hand-Foot Skin Reaction with Regorafenib Efficacy in the Treatment of Metastatic Colorectal Cancer.

Kobayashi K, Kawakami K, Yokokawa T, Aoyama T, Suzuki K, Wakatsuki T, Suenaga M, Sato H, Sugiyama E, Yamaguchi K, Hama T.

Oncology. 2019;96(4):200-206. doi: 10.1159/000495989. Epub 2019 Feb 14.

PMID:
30763946
16.

A Rare Case of IgG4-Related Disease Presenting as a Unilateral Severe Dacryoadenitis Complicated by Hypophysitis and Hypertrophic Pachymeningitis.

Yoshida Y, Kondo T, Hosokawa Y, Oki K, Yukawa K, Araki K, Kohno H, Kuranobu T, Tokunaga T, Oi K, Sugimoto T, Oda K, Nojima T, Hirata S, Sugiyama E.

J Clin Rheumatol. 2019 Feb 1. doi: 10.1097/RHU.0000000000000989. [Epub ahead of print] No abstract available.

PMID:
30724757
17.

Tumour necrosis factor α augments the inhibitory effects of CTLA-4-Ig on osteoclast generation from human monocytes via induction of CD80 expression.

Oi K, Tokunaga T, Kuranobu T, Yukawa K, Kohno H, Yoshida Y, Mokuda S, Hirata S, Sugiyama E.

Clin Exp Immunol. 2019 Jun;196(3):392-402. doi: 10.1111/cei.13271. Epub 2019 Feb 27.

PMID:
30724348
18.

A Large Deep Skin Ulcer as an Initial Manifestation of Systemic Cryptococcosis.

Araki K, Yoshida Y, Kohno H, Sugiyama E.

Mycopathologia. 2019 Apr;184(2):341-343. doi: 10.1007/s11046-019-00322-1. Epub 2019 Feb 1.

PMID:
30710325
19.

The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice.

Munenaga S, Ouhara K, Hamamoto Y, Kajiya M, Takeda K, Yamasaki S, Kawai T, Mizuno N, Fujita T, Sugiyama E, Kurihara H.

Arthritis Res Ther. 2018 Nov 3;20(1):247. doi: 10.1186/s13075-018-1744-3.

20.

Peroxisome proliferator-activated receptor α attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice.

Lu Y, Harada M, Kamijo Y, Nakajima T, Tanaka N, Sugiyama E, Kyogashima M, Gonzalez FJ, Aoyama T.

Arch Toxicol. 2019 Jan;93(1):149-161. doi: 10.1007/s00204-018-2335-4. Epub 2018 Oct 19.

21.

Autoantibodies reactive to PEP08 are clinically related with morbidity and severity of interstitial lung disease in connective tissue diseases.

Okumura M, Ozawa T, Hamana H, Norimatsu Y, Tsuda R, Kobayashi E, Shinoda K, Taki H, Tobe K, Imura J, Sugiyama E, Kishi H, Muraguchi A.

Eur J Immunol. 2018 Oct;48(10):1717-1727. doi: 10.1002/eji.201747381. Epub 2018 Jul 25.

22.

Establishment of an Endogenous Clostridium difficile Rat Infection Model and Evaluation of the Effects of Clostridium butyricum MIYAIRI 588 Probiotic Strain.

Oka K, Osaki T, Hanawa T, Kurata S, Sugiyama E, Takahashi M, Tanaka M, Taguchi H, Kamiya S.

Front Microbiol. 2018 Jun 18;9:1264. doi: 10.3389/fmicb.2018.01264. eCollection 2018.

23.

IL-1β Enhances Wnt Signal by Inhibiting DKK1.

Yoshida Y, Yamasaki S, Oi K, Kuranobu T, Nojima T, Miyaki S, Ida H, Sugiyama E.

Inflammation. 2018 Oct;41(5):1945-1954. doi: 10.1007/s10753-018-0838-z.

PMID:
29956067
24.

Visualization of Brain Gangliosides Using MALDI Imaging Mass Spectrometry.

Sugiyama E, Setou M.

Methods Mol Biol. 2018;1804:223-229. doi: 10.1007/978-1-4939-8552-4_10.

PMID:
29926411
25.

Clinical value of autoantibodies for lupus myelitis and its subtypes: A systematic review.

Oiwa H, Kuriyama A, Matsubara T, Sugiyama E.

Semin Arthritis Rheum. 2018 Oct;48(2):214-220. doi: 10.1016/j.semarthrit.2018.02.004. Epub 2018 Feb 14.

PMID:
29580564
26.

Reparative bone-like tissue formation in the tooth of a systemic sclerosis patient.

Matsuda S, Memida T, Mizuno N, Ogawa I, Ouhara K, Kajiya M, Fujita T, Sugiyama E, Kurihara H.

Int Endod J. 2018 Sep;51(9):1059-1066. doi: 10.1111/iej.12914. Epub 2018 Mar 14.

PMID:
29480950
27.

The induced RNA-binding protein, HuR, targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis.

Ouhara K, Munenaga S, Kajiya M, Takeda K, Matsuda S, Sato Y, Hamamoto Y, Iwata T, Yamasaki S, Akutagawa K, Mizuno N, Fujita T, Sugiyama E, Kurihara H.

Clin Exp Immunol. 2018 Jun;192(3):325-336. doi: 10.1111/cei.13110. Epub 2018 Mar 8.

28.

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system.

Watanabe M, Sugiura Y, Sugiyama E, Narita M, Navratilova E, Kondo T, Uchiyama N, Yamanaka A, Kuzumaki N, Porreca F, Narita M.

Mol Pain. 2018 Jan-Dec;14:1744806918754934. doi: 10.1177/1744806918754934. Epub 2018 Jan 8.

29.

Glycosphingolipid metabolic reprogramming drives neural differentiation.

Russo D, Della Ragione F, Rizzo R, Sugiyama E, Scalabrì F, Hori K, Capasso S, Sticco L, Fioriniello S, De Gregorio R, Granata I, Guarracino MR, Maglione V, Johannes L, Bellenchi GC, Hoshino M, Setou M, D'Esposito M, Luini A, D'Angelo G.

EMBO J. 2018 Apr 3;37(7). pii: e97674. doi: 10.15252/embj.201797674. Epub 2017 Dec 27.

30.

Utilizing mass spectrometry imaging to map the thyroid hormones triiodothyronine and thyroxine in Xenopus tropicalis tadpoles.

Goto-Inoue N, Sato T, Morisasa M, Kashiwagi A, Kashiwagi K, Sugiura Y, Sugiyama E, Suematsu M, Mori T.

Anal Bioanal Chem. 2018 Feb;410(4):1333-1340. doi: 10.1007/s00216-017-0775-y. Epub 2017 Dec 15.

PMID:
29247380
31.

Visualization of local phosphatidylcholine synthesis within hippocampal neurons using a compartmentalized culture system and imaging mass spectrometry.

Sugiyama E, Yao I, Setou M.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1048-1054. doi: 10.1016/j.bbrc.2017.11.108. Epub 2017 Nov 21.

PMID:
29162450
32.

Comparison of DWIBS/T2 image fusion and PET/CT for the diagnosis of cancer in the abdominal cavity.

Tomizawa M, Shinozaki F, Uchida Y, Uchiyama K, Tanaka S, Sunaoshi T, Kano D, Sugiyama E, Shite M, Haga R, Fukamizu Y, Fujita T, Kagayama S, Hasegawa R, Shirai Y, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.

Exp Ther Med. 2017 Oct;14(4):3754-3760. doi: 10.3892/etm.2017.4987. Epub 2017 Aug 22.

33.

Cerebral Microbleeds Remain for Nine Years: A Prospective Study with Yearly Magnetic Resonance Imaging.

Saito T, Kawamura Y, Sato N, Sugiyama E, Okada M, Takeuchi T, Akasaka K, Hasebe N.

J Stroke Cerebrovasc Dis. 2018 Feb;27(2):315-320. doi: 10.1016/j.jstrokecerebrovasdis.2017.09.001. Epub 2017 Sep 29.

PMID:
28969880
34.

Neurological Complications in Eosinophilic Granulomatosis with Polyangiitis (EGPA): The Roles of History and Physical Examinations in the Diagnosis of EGPA.

Oiwa H, Mokuda S, Matsubara T, Funaki M, Takeda I, Yamawaki T, Kumagai K, Sugiyama E.

Intern Med. 2017 Nov 15;56(22):3003-3008. doi: 10.2169/internalmedicine.8457-16. Epub 2017 Sep 15.

35.

Comparison of adverse events following injection of original or generic docetaxel for the treatment of breast cancer.

Tagawa N, Sugiyama E, Tajima M, Sasaki Y, Nakamura S, Okuyama H, Shimizu H, Sato VH, Sasaki T, Sato H.

Cancer Chemother Pharmacol. 2017 Oct;80(4):841-849. doi: 10.1007/s00280-017-3425-3. Epub 2017 Sep 1.

PMID:
28864856
36.

Recurrent triple-negative breast cancer (TNBC) tissues contain a higher amount of phosphatidylcholine (32:1) than non-recurrent TNBC tissues.

Hosokawa Y, Masaki N, Takei S, Horikawa M, Matsushita S, Sugiyama E, Ogura H, Shiiya N, Setou M.

PLoS One. 2017 Aug 23;12(8):e0183724. doi: 10.1371/journal.pone.0183724. eCollection 2017.

37.

Decreased Fatty Acid β-Oxidation Is the Main Cause of Fatty Liver Induced by Polyunsaturated Fatty Acid Deficiency in Mice.

Nakajima T, Yang Y, Lu Y, Kamijo Y, Yamada Y, Nakamura K, Koyama M, Yamaguchi S, Sugiyama E, Tanaka N, Aoyama T.

Tohoku J Exp Med. 2017 Jul;242(3):229-239. doi: 10.1620/tjem.242.229.

38.

Diagnosis of complications associated with acute cholecystitis using computed tomography and diffusion-weighted imaging with background body signal suppression/T2 image fusion.

Tomizawa M, Shinozaki F, Tanaka S, Sunaoshi T, Kano D, Sugiyama E, Shite M, Haga R, Fukamizu Y, Fujita T, Kagayama S, Hasegawa R, Shirai Y, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.

Exp Ther Med. 2017 Jul;14(1):743-747. doi: 10.3892/etm.2017.4567. Epub 2017 Jun 8.

39.

Diffusion-weighted whole-body magnetic resonance imaging with background body signal suppression/T2 image fusion for the diagnosis of acute cholecystitis.

Tomizawa M, Shinozaki F, Tanaka S, Sunaoshi T, Kano D, Sugiyama E, Shite M, Haga R, Fukamizu Y, Fujita T, Kagayama S, Hasegawa R, Shirai Y, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.

Exp Ther Med. 2017 Jul;14(1):730-734. doi: 10.3892/etm.2017.4561. Epub 2017 Jun 8.

40.

A report of three cases with lupus myelitis.

Oiwa H, Yamabe T, Kawashima M, Maetani Y, Agari D, Yamawaki T, Sugiyama E.

Eur J Rheumatol. 2017 Jun;4(2):148-150. doi: 10.5152/eurjrheum.2017.160099. Epub 2017 Jun 1. Erratum in: Eur J Rheumatol. 2017 Sep;4(3):238.

41.

Diagnostic accuracy of diffusion-weighted whole-body imaging with background body signal suppression/T2-weighted image fusion for the detection of abdominal solid cancer.

Tomizawa M, Shinozaki F, Fugo K, Tanaka S, Sunaoshi T, Kano D, Sugiyama E, Shite M, Haga R, Fukamizu Y, Fujita T, Kagayama S, Hasegawa R, Togawa A, Shirai Y, Ichiki N, Oshima Y, Koike N, Toshimitsu Y, Motoyoshi Y, Sugiyama T, Yamamoto S, Kishimoto T, Ishige N.

Exp Ther Med. 2017 Jun;13(6):3509-3515. doi: 10.3892/etm.2017.4432. Epub 2017 May 5.

42.

Clinical features and predictive value of serum inflammatory markers of perivascular involvement in immunoglobulin G4-related disease.

Yamamoto H, Sugiyama E, Serikawa M, Tatsugami F, Yokozaki M, Kitagawa T, Senoo A, Nakamoto YK, Awai K, Chayama K, Kihara Y.

Heart Vessels. 2017 Oct;32(10):1176-1185. doi: 10.1007/s00380-017-0987-2. Epub 2017 May 4.

PMID:
28474137
43.

Diffusion-weighted whole-body imaging with background body signal suppression/T2 image fusion for the diagnosis of colorectal polyp and cancer.

Tomizawa M, Shinozaki F, Uchida Y, Uchiyama K, Fugo K, Sunaoshi T, Ozaki A, Sugiyama E, Baba A, Kano D, Shite M, Haga R, Fukamizu Y, Kagayama S, Hasegawa R, Shirai Y, Motoyoshi Y, Sugiyama T, Yamamoto S, Kishimoto T, Ishige N.

Exp Ther Med. 2017 Feb;13(2):639-644. doi: 10.3892/etm.2016.3981. Epub 2016 Dec 16.

44.

Selective improvement of peptides imaging on tissue by supercritical fluid wash of lipids for matrix-assisted laser desorption/ionization mass spectrometry.

Matsushita S, Masaki N, Sato K, Hayasaka T, Sugiyama E, Hui SP, Chiba H, Mase N, Setou M.

Anal Bioanal Chem. 2017 Feb;409(6):1475-1480. doi: 10.1007/s00216-016-0119-3. Epub 2016 Dec 9.

PMID:
27942804
45.

Activation of PPARα by Fatty Acid Accumulation Enhances Fatty Acid Degradation and Sulfatide Synthesis.

Yang Y, Feng Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Aoyama T.

Tohoku J Exp Med. 2016 Oct;240(2):113-22. doi: 10.1620/tjem.240.113.

46.

Successful treatment with afatinib after grade 3 hepatotoxicity induced by both gefitinib and erlotinib in EGFR mutation-positive non-small cell lung cancer.

Zenke Y, Umemura S, Sugiyama E, Kirita K, Matsumoto S, Yoh K, Niho S, Ohmatsu H, Goto K.

Lung Cancer. 2016 Sep;99:1-3. doi: 10.1016/j.lungcan.2016.05.002. Epub 2016 Jun 6.

PMID:
27565905
47.
48.

Porphyromonas gingivalis infection exacerbates the onset of rheumatoid arthritis in SKG mice.

Yamakawa M, Ouhara K, Kajiya M, Munenaga S, Kittaka M, Yamasaki S, Takeda K, Takeshita K, Mizuno N, Fujita T, Sugiyama E, Kurihara H.

Clin Exp Immunol. 2016 Nov;186(2):177-189. doi: 10.1111/cei.12847. Epub 2016 Aug 29.

49.

Accumulation of arachidonic acid-containing phosphatidylinositol at the outer edge of colorectal cancer.

Hiraide T, Ikegami K, Sakaguchi T, Morita Y, Hayasaka T, Masaki N, Waki M, Sugiyama E, Shinriki S, Takeda M, Shibasaki Y, Miyazaki S, Kikuchi H, Okuyama H, Inoue M, Setou M, Konno H.

Sci Rep. 2016 Jul 20;6:29935. doi: 10.1038/srep29935.

50.

Diffusion-weighted whole-body imaging with background body signal suppression/T2-weighted image fusion of gastrointestinal cancers.

Tomizawa M, Shinozaki F, Fugo K, Sunaoshi T, Kano D, Tanaka S, Ozaki A, Sugiyama E, Shite M, Haga R, Baba A, Fukamizu Y, Fujita T, Kagayama S, Hasegawa R, Togawa A, Shirai Y, Ichiki N, Motoyoshi Y, Sugiyama T, Yamamoto S, Kishimoto T, Ishige N.

Mol Clin Oncol. 2016 Jul;5(1):44-48. Epub 2016 May 11.

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