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Items: 1 to 50 of 69

1.

The Creation of a Sustainable Otolaryngology Department in Malawi.

Vandjelovic ND, Sugihara EM, Mulwafu W, Madgy DN.

Ear Nose Throat J. 2019 Jun 6:145561319855366. doi: 10.1177/0145561319855366. [Epub ahead of print]

PMID:
31170820
2.

ROCK Inhibition Induces Terminal Adipocyte Differentiation and Suppresses Tumorigenesis in Chemoresistant Osteosarcoma Cells.

Takahashi N, Nobusue H, Shimizu T, Sugihara E, Yamaguchi-Iwai S, Onishi N, Kunitomi H, Kuroda T, Saya H.

Cancer Res. 2019 Jun 15;79(12):3088-3099. doi: 10.1158/0008-5472.CAN-18-2693. Epub 2019 Apr 16.

PMID:
30992323
3.

The effect of intratympanic steroid injection frequency in idiopathic sudden sensorineural hearing loss.

Sugihara EM, Evans MA, Neumann M, Babu SC.

Am J Otolaryngol. 2018 Nov - Dec;39(6):688-692. doi: 10.1016/j.amjoto.2018.07.013. Epub 2018 Jul 20.

PMID:
30076018
4.

T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system.

Tamai M, Inukai T, Kojika S, Abe M, Kagami K, Harama D, Shinohara T, Watanabe A, Oshiro H, Akahane K, Goi K, Sugihara E, Nakada S, Sugita K.

Sci Rep. 2018 Jul 2;8(1):9966. doi: 10.1038/s41598-018-27767-6.

5.

Comment on "Mastoid and Inner Ear Measurements in Patients With MeniÈre's Disease".

Sugihara EM, Babu SC.

Otol Neurotol. 2018 Jun;39(5):661. doi: 10.1097/MAO.0000000000001775. No abstract available.

PMID:
29561380
6.

Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma.

Semba T, Sugihara E, Kamoshita N, Ueno S, Fukuda K, Yoshino M, Takao K, Yoshikawa K, Izuhara K, Arima Y, Suzuki M, Saya H.

Cancer Sci. 2018 May;109(5):1447-1454. doi: 10.1111/cas.13554. Epub 2018 Mar 31.

7.

Clofarabine exerts antileukemic activity against cytarabine-resistant B-cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression.

Huang M, Inukai T, Miyake K, Tanaka Y, Kagami K, Abe M, Goto H, Minegishi M, Iwamoto S, Sugihara E, Watanabe A, Somazu S, Shinohara T, Oshiro H, Akahane K, Goi K, Sugita K.

Cancer Med. 2018 Apr;7(4):1297-1316. doi: 10.1002/cam4.1323. Epub 2018 Feb 23.

8.

Development of a functional thyroid model based on an organoid culture system.

Saito Y, Onishi N, Takami H, Seishima R, Inoue H, Hirata Y, Kameyama K, Tsuchihashi K, Sugihara E, Uchino S, Ito K, Kawakubo H, Takeuchi H, Kitagawa Y, Saya H, Nagano O.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):783-789. doi: 10.1016/j.bbrc.2018.02.154. Epub 2018 Feb 19.

PMID:
29470983
9.

Mastoid and Inner Ear Measurements in Patients With Menière's Disease.

Sugihara EM, Marinica AL, Vandjelovic ND, Kelley BM, Sana SS, Starkey NE, Babu SC.

Otol Neurotol. 2017 Dec;38(10):1484-1489. doi: 10.1097/MAO.0000000000001576.

PMID:
29099441
10.

Acquired External Auditory Canal Atresia: A Comparison of Acellular Dermal Matrix and Split-thickness Skin Grafting Techniques.

Evans MA, Sugihara EM, Chan EY.

Otol Neurotol. 2017 Sep;38(8):1149-1152. doi: 10.1097/MAO.0000000000001487.

PMID:
28727650
11.

FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia.

Ishizawa J, Sugihara E, Kuninaka S, Mogushi K, Kojima K, Benton CB, Zhao R, Chachad D, Hashimoto N, Jacamo RO, Qiu Y, Yoo SY, Okamoto S, Andreeff M, Kornblau SM, Saya H.

Blood. 2017 Apr 6;129(14):1958-1968. doi: 10.1182/blood-2016-07-726216. Epub 2017 Jan 31.

12.

Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity.

Kamel WA, Sugihara E, Nobusue H, Yamaguchi-Iwai S, Onishi N, Maki K, Fukuchi Y, Matsuo K, Muto A, Saya H, Shimizu T.

Mol Cancer Ther. 2017 Jan;16(1):182-192. doi: 10.1158/1535-7163.MCT-16-0499. Epub 2016 Oct 31.

13.

Incidence of Pediatric Superior Semicircular Canal Dehiscence and Inner Ear Anomalies: A Large Multicenter Review.

Sugihara EM, Babu SC, Kitsko DJ, Haupert MS, Thottam PJ.

Otol Neurotol. 2016 Oct;37(9):1370-5. doi: 10.1097/MAO.0000000000001194.

PMID:
27636391
14.

CD44 variant-dependent redox status regulation in liver fluke-associated cholangiocarcinoma: A target for cholangiocarcinoma treatment.

Thanee M, Loilome W, Techasen A, Sugihara E, Okazaki S, Abe S, Ueda S, Masuko T, Namwat N, Khuntikeo N, Titapun A, Pairojkul C, Saya H, Yongvanit P.

Cancer Sci. 2016 Jul;107(7):991-1000. doi: 10.1111/cas.12967. Epub 2016 Jun 20.

15.

MIF Maintains the Tumorigenic Capacity of Brain Tumor-Initiating Cells by Directly Inhibiting p53.

Fukaya R, Ohta S, Yaguchi T, Matsuzaki Y, Sugihara E, Okano H, Saya H, Kawakami Y, Kawase T, Yoshida K, Toda M.

Cancer Res. 2016 May 1;76(9):2813-23. doi: 10.1158/0008-5472.CAN-15-1011. Epub 2016 Mar 15.

16.

CD44 variant 9 is a potential biomarker of tumor initiating cells predicting survival outcome in hepatitis C virus-positive patients with resected hepatocellular carcinoma.

Kakehashi A, Ishii N, Sugihara E, Gi M, Saya H, Wanibuchi H.

Cancer Sci. 2016 May;107(5):609-18. doi: 10.1111/cas.12908. Epub 2016 Mar 28.

17.

Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.

Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, Saya H, Amagai M, Nagao K.

Nat Med. 2015 Nov;21(11):1272-9. doi: 10.1038/nm.3962. Epub 2015 Oct 19.

18.

Periostin Is a Key Niche Component for Wound Metastasis of Melanoma.

Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, Saya H.

PLoS One. 2015 Jun 17;10(6):e0129704. doi: 10.1371/journal.pone.0129704. eCollection 2015.

19.

Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells.

Yamaguchi SI, Ueki A, Sugihara E, Onishi N, Yaguchi T, Kawakami Y, Horiuchi K, Morioka H, Matsumoto M, Nakamura M, Muto A, Toyama Y, Saya H, Shimizu T.

Cancer Sci. 2015 Jul;106(7):875-82. doi: 10.1111/cas.12686. Epub 2015 May 26. Erratum in: Cancer Sci. 2015 Sep;106(9):1249.

20.

IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress.

Shimizu T, Sugihara E, Yamaguchi-Iwai S, Tamaki S, Koyama Y, Kamel W, Ueki A, Ishikawa T, Chiyoda T, Osuka S, Onishi N, Ikeda H, Kamei J, Matsuo K, Fukuchi Y, Nagai T, Toguchida J, Toyama Y, Muto A, Saya H.

Cancer Res. 2014 Nov 15;74(22):6531-41. doi: 10.1158/0008-5472.CAN-14-0914. Epub 2014 Oct 1.

21.

Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells.

Hosonaga M, Arima Y, Sugihara E, Kohno N, Saya H.

Cancer Sci. 2014 Jul;105(7):779-87. doi: 10.1111/cas.12427. Epub 2014 Jun 2.

22.

Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation.

Nobusue H, Onishi N, Shimizu T, Sugihara E, Oki Y, Sumikawa Y, Chiyoda T, Akashi K, Saya H, Kano K.

Nat Commun. 2014 Feb 26;5:3368. doi: 10.1038/ncomms4368.

PMID:
24569594
23.

Age-specific effectiveness and safety of newly initiated insulin therapy in Japanese patients with uncontrolled diabetes.

Shiga T, Yokokawa H, Taneda Y, Sugihara E, Meijyo M, Mitsuhashi K, Hisaoka T, Isonuma H.

Diabetes Ther. 2013 Dec;4(2):473-86. doi: 10.1007/s13300-013-0049-4. Epub 2013 Dec 10.

24.

(Micro)spectroscopic analyses of particle size dependence on arsenic distribution and speciation in mine wastes.

Kim CS, Chi C, Miller SR, Rosales RA, Sugihara ES, Akau J, Rytuba JJ, Webb SM.

Environ Sci Technol. 2013 Aug 6;47(15):8164-71. doi: 10.1021/es4010653. Epub 2013 Jul 26.

PMID:
23889478
25.

Twist2 functions as a tumor suppressor in murine osteosarcoma cells.

Ishikawa T, Shimizu T, Ueki A, Yamaguchi SI, Onishi N, Sugihara E, Kuninaka S, Miyamoto T, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Mabuchi Y, Matsuzaki Y, Yamaguchi R, Miyano S, Saya H.

Cancer Sci. 2013 Jul;104(7):880-8. doi: 10.1111/cas.12163. Epub 2013 May 9.

26.

The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs.

Atsumi Y, Inase A, Osawa T, Sugihara E, Sakasai R, Fujimori H, Teraoka H, Saya H, Kanno M, Tashiro F, Nakagama H, Masutani M, Yoshioka K.

J Biol Chem. 2013 May 10;288(19):13269-77. doi: 10.1074/jbc.M112.402560. Epub 2013 Mar 27.

27.

Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes.

Osawa T, Atsumi Y, Sugihara E, Saya H, Kanno M, Tashiro F, Masutani M, Yoshioka K.

Biochem Biophys Res Commun. 2013 Mar 1;432(1):34-9. doi: 10.1016/j.bbrc.2013.01.091. Epub 2013 Jan 31.

PMID:
23376716
28.

IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells.

Osuka S, Sampetrean O, Shimizu T, Saga I, Onishi N, Sugihara E, Okubo J, Fujita S, Takano S, Matsumura A, Saya H.

Stem Cells. 2013 Apr;31(4):627-40. doi: 10.1002/stem.1328.

29.

xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma.

Yoshikawa M, Tsuchihashi K, Ishimoto T, Yae T, Motohara T, Sugihara E, Onishi N, Masuko T, Yoshizawa K, Kawashiri S, Mukai M, Asoda S, Kawana H, Nakagawa T, Saya H, Nagano O.

Cancer Res. 2013 Mar 15;73(6):1855-66. doi: 10.1158/0008-5472.CAN-12-3609-T. Epub 2013 Jan 14.

30.

Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.

Ueki A, Shimizu T, Masuda K, Yamaguchi SI, Ishikawa T, Sugihara E, Onishi N, Kuninaka S, Miyoshi K, Muto A, Toyama Y, Banno K, Aoki D, Saya H.

PLoS One. 2012;7(11):e50621. doi: 10.1371/journal.pone.0050621. Epub 2012 Nov 30.

31.

Complexity of cancer stem cells.

Sugihara E, Saya H.

Int J Cancer. 2013 Mar 15;132(6):1249-59. doi: 10.1002/ijc.27961. Epub 2012 Dec 17. Review.

32.

Phase I/II multicenter study of transarterial chemoembolization with a cisplatin fine powder and porous gelatin particles for unresectable hepatocellular carcinoma: Japan Interventional Radiology in Oncology Study Group Study 0401.

Osuga K, Arai Y, Anai H, Takeuchi Y, Aramaki T, Sugihara E, Yamamoto T, Inaba Y, Ganaha F, Seki H, Sadaoka S, Sato M, Kobayashi T, Kodama Y, Inoh S, Yamakado K.

J Vasc Interv Radiol. 2012 Oct;23(10):1278-85. doi: 10.1016/j.jvir.2012.06.028. Epub 2012 Aug 24.

PMID:
22922041
33.

Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells.

Tamada M, Nagano O, Tateyama S, Ohmura M, Yae T, Ishimoto T, Sugihara E, Onishi N, Yamamoto T, Yanagawa H, Suematsu M, Saya H.

Cancer Res. 2012 Mar 15;72(6):1438-48. doi: 10.1158/0008-5472.CAN-11-3024. Epub 2012 Jan 31.

34.

Fibroblast growth factor-2 is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma.

Shimizu T, Ishikawa T, Iwai S, Ueki A, Sugihara E, Onishi N, Kuninaka S, Miyamoto T, Toyama Y, Ijiri H, Mori H, Matsuzaki Y, Yaguchi T, Nishio H, Kawakami Y, Ikeda Y, Saya H.

Mol Cancer Res. 2012 Mar;10(3):454-68. doi: 10.1158/1541-7786.MCR-11-0347. Epub 2012 Jan 6.

35.

Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor.

Sugihara E, Shimizu T, Kojima K, Onishi N, Kai K, Ishizawa J, Nagata K, Hashimoto N, Honda H, Kanno M, Miwa M, Okada S, Andreeff M, Saya H.

Oncogene. 2012 Jun 7;31(23):2849-61. doi: 10.1038/onc.2011.462. Epub 2011 Oct 10.

36.

Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells.

Sampetrean O, Saga I, Nakanishi M, Sugihara E, Fukaya R, Onishi N, Osuka S, Akahata M, Kai K, Sugimoto H, Hirao A, Saya H.

Neoplasia. 2011 Sep;13(9):784-91.

37.

Establishment of a choriocarcinoma model from immortalized normal extravillous trophoblast cells transduced with HRASV12.

Kobayashi Y, Shimizu T, Naoe H, Ueki A, Ishizawa J, Chiyoda T, Onishi N, Sugihara E, Nagano O, Banno K, Kuninaka S, Aoki D, Saya H.

Am J Pathol. 2011 Sep;179(3):1471-82. doi: 10.1016/j.ajpath.2011.05.019. Epub 2011 Jul 23.

38.

Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer.

Arima Y, Hayashi N, Hayashi H, Sasaki M, Kai K, Sugihara E, Abe E, Yoshida A, Mikami S, Nakamura S, Saya H.

Int J Cancer. 2012 Jun 1;130(11):2568-79. doi: 10.1002/ijc.26271. Epub 2011 Aug 24.

39.

The cell cycle regulator Cdh1 controls the pool sizes of hematopoietic stem cells and mature lineage progenitors by protecting from genotoxic stress.

Ishizawa J, Kuninaka S, Sugihara E, Naoe H, Kobayashi Y, Chiyoda T, Ueki A, Araki K, Yamamura K, Matsuzaki Y, Nakajima H, Ikeda Y, Okamoto S, Saya H.

Cancer Sci. 2011 May;102(5):967-74. doi: 10.1111/j.1349-7006.2011.01884.x. Epub 2011 Feb 23.

40.

c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.

Shimizu T, Ishikawa T, Sugihara E, Kuninaka S, Miyamoto T, Mabuchi Y, Matsuzaki Y, Tsunoda T, Miya F, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Kawai A, Ichikawa H, Hasegawa T, Okada S, Ito T, Ikeda Y, Suda T, Saya H.

Oncogene. 2010 Oct 21;29(42):5687-99. doi: 10.1038/onc.2010.312. Epub 2010 Aug 2.

PMID:
20676132
41.

Transarterial embolization of large complex arteriovenous fistula associated with hip joint surgery.

Chun HJ, Osuga K, Sugihara E, Tsukaguchi I, Ohsawa S, Tsuda K.

Jpn J Radiol. 2010 Jul;28(6):489-92. doi: 10.1007/s11604-010-0455-8. Epub 2010 Jul 27.

PMID:
20661703
42.

[Clinical analysis of mortality in elderly patients with community-acquired pneumonia].

Sakamoto N, Sugihara E, Boku S, Fukuda H, Isonuma H, Aiba M, Dambara T.

Nihon Ronen Igakkai Zasshi. 2010;47(1):47-51. Japanese.

43.

Myristoylated alanine-rich C kinase substrate phosphorylation promotes cholangiocarcinoma cell migration and metastasis via the protein kinase C-dependent pathway.

Techasen A, Loilome W, Namwat N, Takahashi E, Sugihara E, Puapairoj A, Miwa M, Saya H, Yongvanit P.

Cancer Sci. 2010 Mar;101(3):658-65. doi: 10.1111/j.1349-7006.2009.01427.x. Epub 2009 Nov 7.

44.

Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model.

Kai K, Nagano O, Sugihara E, Arima Y, Sampetrean O, Ishimoto T, Nakanishi M, Ueno NT, Iwase H, Saya H.

Cancer Sci. 2009 Dec;100(12):2275-82. doi: 10.1111/j.1349-7006.2009.01318.x. Epub 2009 Aug 19.

45.

Reduction of human T-cell leukemia virus type-1 infection in mice lacking nuclear factor-kappaB-inducing kinase.

Nitta T, Tanaka M, Sun B, Sugihara E, Kimura M, Kamada Y, Takahashi H, Hanai S, Jiang SW, Fujisawa J, Miwa M.

Cancer Sci. 2008 May;99(5):872-8. doi: 10.1111/j.1349-7006.2008.00766.x. Epub 2008 Feb 27.

46.

[Clinical study on lung disease caused by non-tuberculous mycobacteriosis in the elderly].

Sugihara E, Dambara T, Aiba M, Fukuda Y, Nakajima N, Inui A, Matsumoto N, Hada N, Katayama A, Naito T, Isonuma H, Hayashida Y.

Nihon Ronen Igakkai Zasshi. 2007 Jul;44(4):503-6. Japanese.

47.

Clinical characteristics of 8 sporadic cases of community-acquired Legionella pneumonia in advanced age.

Sugihara E, Dambara T, Aiba M, Okamoto M, Yonemitsu J, Sonobe S, Koga H, Inui A, Hada N, Matsumoto N, Goto Y, Naito T, Isonuma H, Hayashida Y.

Intern Med. 2007;46(8):461-5. Epub 2007 Apr 17.

48.

Preoperative evaluation of perigastric vascular anatomy by 3-dimensional computed tomographic angiography using 16-channel multidetector-row computed tomography for laparoscopic gastrectomy in patients with early gastric cancer.

Kumano S, Tsuda T, Tanaka H, Hirata M, Kim T, Murakami T, Sugihara E, Abe H, Yamashita H, Kobayashi N, Mochizuki T.

J Comput Assist Tomogr. 2007 Jan-Feb;31(1):93-7.

PMID:
17259839
49.

Centrosome amplification in adult T-cell leukemia and human T-cell leukemia virus type 1 Tax-induced human T cells.

Nitta T, Kanai M, Sugihara E, Tanaka M, Sun B, Nagasawa T, Sonoda S, Saya H, Miwa M.

Cancer Sci. 2006 Sep;97(9):836-41. Epub 2006 Jun 29.

50.

Suppression of centrosome amplification after DNA damage depends on p27 accumulation.

Sugihara E, Kanai M, Saito S, Nitta T, Toyoshima H, Nakayama K, Nakayama KI, Fukasawa K, Schwab M, Saya H, Miwa M.

Cancer Res. 2006 Apr 15;66(8):4020-9.

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