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Items: 1 to 50 of 101

1.

Chemically defined and growth-factor-free culture system for the expansion and derivation of human pluripotent stem cells.

Yasuda SY, Ikeda T, Shahsavarani H, Yoshida N, Nayer B, Hino M, Vartak-Sharma N, Suemori H, Hasegawa K.

Nat Biomed Eng. 2018 Mar;2(3):173-182. doi: 10.1038/s41551-018-0200-7. Epub 2018 Mar 5.

PMID:
31015717
2.

Laser-assisted cell removing (LACR) technology contributes to the purification process of the undifferentiated cell fraction during pluripotent stem cell culture.

Teramura T, Matsuda K, Takehara T, Shinohara K, Miyashita Y, Mieno Y, Mori T, Fukuda K, Suzuki K, Suemori H.

Biochem Biophys Res Commun. 2018 Sep 18;503(4):3114-3120. doi: 10.1016/j.bbrc.2018.08.101. Epub 2018 Aug 22.

3.

Isolation and characterization of ventricular-like cells derived from NKX2-5eGFP/w and MLC2vmCherry/w double knock-in human pluripotent stem cells.

Yamauchi K, Li J, Morikawa K, Liu L, Shirayoshi Y, Nakatsuji N, Elliott DA, Hisatome I, Suemori H.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1278-1284. doi: 10.1016/j.bbrc.2017.11.133. Epub 2017 Nov 22.

PMID:
29175323
4.

Efficient Adhesion Culture of Human Pluripotent Stem Cells Using Laminin Fragments in an Uncoated Manner.

Miyazaki T, Isobe T, Nakatsuji N, Suemori H.

Sci Rep. 2017 Jan 30;7:41165. doi: 10.1038/srep41165.

5.

Magnesium chloride and polyamine can differentiate mouse embryonic stem cells into trophectoderm or endoderm.

Tanase JI, Yokoo T, Matsumura Y, Kinoshita M, Kikuchi Y, Suemori H, Ohyama T.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):764-770. doi: 10.1016/j.bbrc.2016.11.108. Epub 2016 Nov 19.

PMID:
27876565
6.

Slow Cooling Cryopreservation Optimized to Human Pluripotent Stem Cells.

Miyazaki T, Suemori H.

Adv Exp Med Biol. 2016;951:57-65. Review.

PMID:
27837554
7.

Long-term maintenance of human induced pluripotent stem cells by automated cell culture system.

Konagaya S, Ando T, Yamauchi T, Suemori H, Iwata H.

Sci Rep. 2015 Nov 17;5:16647. doi: 10.1038/srep16647.

8.

OpenTein: a database of digital whole-slide images of stem cell-derived teratomas.

Park SJ, Komiyama Y, Suemori H, Umezawa A, Nakai K.

Nucleic Acids Res. 2016 Jan 4;44(D1):D1000-4. doi: 10.1093/nar/gkv1096. Epub 2015 Oct 22.

9.

Creation of Mice Bearing a Partial Duplication of HPRT Gene Marked with a GFP Gene and Detection of Revertant Cells In Situ as GFP-Positive Somatic Cells.

Noda A, Suemori H, Hirai Y, Hamasaki K, Kodama Y, Mitani H, Landes RD, Nakamura N.

PLoS One. 2015 Aug 21;10(8):e0136041. doi: 10.1371/journal.pone.0136041. eCollection 2015.

10.

Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI).

Andrews PW, Baker D, Benvinisty N, Miranda B, Bruce K, Brüstle O, Choi M, Choi YM, Crook JM, de Sousa PA, Dvorak P, Freund C, Firpo M, Furue MK, Gokhale P, Ha HY, Han E, Haupt S, Healy L, Hei DJ, Hovatta O, Hunt C, Hwang SM, Inamdar MS, Isasi RM, Jaconi M, Jekerle V, Kamthorn P, Kibbey MC, Knezevic I, Knowles BB, Koo SK, Laabi Y, Leopoldo L, Liu P, Lomax GP, Loring JF, Ludwig TE, Montgomery K, Mummery C, Nagy A, Nakamura Y, Nakatsuji N, Oh S, Oh SK, Otonkoski T, Pera M, Peschanski M, Pranke P, Rajala KM, Rao M, Ruttachuk R, Reubinoff B, Ricco L, Rooke H, Sipp D, Stacey GN, Suemori H, Takahashi TA, Takada K, Talib S, Tannenbaum S, Yuan BZ, Zeng F, Zhou Q.

Regen Med. 2015;10(2 Suppl):1-44. doi: 10.2217/rme.14.93. No abstract available.

PMID:
25675265
11.

Cryopreservation of human pluripotent stem cells: a general protocol.

Miyazaki T, Suemori H.

Methods Mol Biol. 2015;1235:97-104. doi: 10.1007/978-1-4939-1785-3_9.

PMID:
25388389
12.

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies.

Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H, Yamazaki S, Sakuma T, Toki T, Shimizu R, Nakauchi H, Yamamoto T, Oshimura M.

Sci Rep. 2014 Aug 27;4:6136. doi: 10.1038/srep06136.

13.

Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells.

Igawa K, Kokubu C, Yusa K, Horie K, Yoshimura Y, Yamauchi K, Suemori H, Yokozeki H, Toyoda M, Kiyokawa N, Okita H, Miyagawa Y, Akutsu H, Umezawa A, Katayama I, Takeda J.

Stem Cells Transl Med. 2014 Sep;3(9):992-1001. doi: 10.5966/sctm.2013-0179. Epub 2014 Jul 14.

14.

Role of retinoic acid and fibroblast growth factor 2 in neural differentiation from cynomolgus monkey (Macaca fascicularis) embryonic stem cells.

Hatori M, Shimozawa N, Yasmin L, Suemori H, Nakatsuji N, Ogura A, Yagami K, Sankai T.

Comp Med. 2014 Apr;64(2):140-7.

15.

Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture.

Takeuchi H, Nakatsuji N, Suemori H.

Sci Rep. 2014 Mar 27;4:4488. doi: 10.1038/srep04488.

16.

A chemical probe that labels human pluripotent stem cells.

Hirata N, Nakagawa M, Fujibayashi Y, Yamauchi K, Murata A, Minami I, Tomioka M, Kondo T, Kuo TF, Endo H, Inoue H, Sato SI, Ando S, Kawazoe Y, Aiba K, Nagata K, Kawase E, Chang YT, Suemori H, Eto K, Nakauchi H, Yamanaka S, Nakatsuji N, Ueda K, Uesugi M.

Cell Rep. 2014 Mar 27;6(6):1165-1174. doi: 10.1016/j.celrep.2014.02.006. Epub 2014 Mar 6.

17.

Enhancement of fluorescence intensity by silicon particles and its size effect.

Saitow K, Suemori H, Tamamitsu H.

Chem Commun (Camb). 2014 Feb 4;50(9):1137-40. doi: 10.1039/c3cc46566g.

PMID:
24325003
18.

Optimization of slow cooling cryopreservation for human pluripotent stem cells.

Miyazaki T, Nakatsuji N, Suemori H.

Genesis. 2014 Jan;52(1):49-55. doi: 10.1002/dvg.22725. Epub 2013 Dec 3.

PMID:
24254533
19.

Identification of small molecules that promote human embryonic stem cell self-renewal.

Kumagai H, Suemori H, Uesugi M, Nakatsuji N, Kawase E.

Biochem Biophys Res Commun. 2013 May 17;434(4):710-6. doi: 10.1016/j.bbrc.2013.03.061. Epub 2013 Mar 27.

PMID:
23541943
20.

The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells.

Takase O, Yoshikawa M, Idei M, Hirahashi J, Fujita T, Takato T, Isagawa T, Nagae G, Suemori H, Aburatani H, Hishikawa K.

PLoS One. 2013;8(2):e56399. doi: 10.1371/journal.pone.0056399. Epub 2013 Feb 20.

21.

Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells.

Miyazaki T, Futaki S, Suemori H, Taniguchi Y, Yamada M, Kawasaki M, Hayashi M, Kumagai H, Nakatsuji N, Sekiguchi K, Kawase E.

Nat Commun. 2012;3:1236. doi: 10.1038/ncomms2231. Erratum in: Nat Commun. 2013;4:1931.

22.

Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.

Hasegawa K, Yasuda SY, Teo JL, Nguyen C, McMillan M, Hsieh CL, Suemori H, Nakatsuji N, Yamamoto M, Miyabayashi T, Lutzko C, Pera MF, Kahn M.

Stem Cells Transl Med. 2012 Jan;1(1):18-28. doi: 10.5966/sctm.2011-0033. Epub 2011 Dec 7.

23.

The SMAD2/3 corepressor SNON maintains pluripotency through selective repression of mesendodermal genes in human ES cells.

Tsuneyoshi N, Tan EK, Sadasivam A, Poobalan Y, Sumi T, Nakatsuji N, Suemori H, Dunn NR.

Genes Dev. 2012 Nov 15;26(22):2471-6. doi: 10.1101/gad.201772.112.

24.

Dynamic link between histone H3 acetylation and an increase in the functional characteristics of human ESC/iPSC-derived cardiomyocytes.

Otsuji TG, Kurose Y, Suemori H, Tada M, Nakatsuji N.

PLoS One. 2012;7(9):e45010. doi: 10.1371/journal.pone.0045010. Epub 2012 Sep 12.

25.

Comparative study of transplantation of hepatocytes at various differentiation stages into mice with lethal liver damage.

Kamimura R, Ishii T, Sasaki N, Kajiwara M, Machimoto T, Saito M, Kohno K, Suemori H, Nakatsuji N, Ikai I, Yasuchika K, Uemoto S.

Cell Transplant. 2012;21(11):2351-62. doi: 10.3727/096368912X636957. Epub 2012 Apr 2.

PMID:
22472047
26.

Prolonged maturation culture favors a reduction in the tumorigenicity and the dopaminergic function of human ESC-derived neural cells in a primate model of Parkinson's disease.

Doi D, Morizane A, Kikuchi T, Onoe H, Hayashi T, Kawasaki T, Motono M, Sasai Y, Saiki H, Gomi M, Yoshikawa T, Hayashi H, Shinoyama M, Refaat MM, Suemori H, Miyamoto S, Takahashi J.

Stem Cells. 2012 May;30(5):935-45. doi: 10.1002/stem.1060.

27.

Efficient and accurate homologous recombination in hESCs and hiPSCs using helper-dependent adenoviral vectors.

Aizawa E, Hirabayashi Y, Iwanaga Y, Suzuki K, Sakurai K, Shimoji M, Aiba K, Wada T, Tooi N, Kawase E, Suemori H, Nakatsuji N, Mitani K.

Mol Ther. 2012 Feb;20(2):424-31. doi: 10.1038/mt.2011.266. Epub 2011 Dec 6.

28.

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

International Stem Cell Initiative, Amps K, Andrews PW, Anyfantis G, Armstrong L, Avery S, Baharvand H, Baker J, Baker D, Munoz MB, Beil S, Benvenisty N, Ben-Yosef D, Biancotti JC, Bosman A, Brena RM, Brison D, Caisander G, Camarasa MV, Chen J, Chiao E, Choi YM, Choo AB, Collins D, Colman A, Crook JM, Daley GQ, Dalton A, De Sousa PA, Denning C, Downie J, Dvorak P, Montgomery KD, Feki A, Ford A, Fox V, Fraga AM, Frumkin T, Ge L, Gokhale PJ, Golan-Lev T, Gourabi H, Gropp M, Lu G, Hampl A, Harron K, Healy L, Herath W, Holm F, Hovatta O, Hyllner J, Inamdar MS, Irwanto AK, Ishii T, Jaconi M, Jin Y, Kimber S, Kiselev S, Knowles BB, Kopper O, Kukharenko V, Kuliev A, Lagarkova MA, Laird PW, Lako M, Laslett AL, Lavon N, Lee DR, Lee JE, Li C, Lim LS, Ludwig TE, Ma Y, Maltby E, Mateizel I, Mayshar Y, Mileikovsky M, Minger SL, Miyazaki T, Moon SY, Moore H, Mummery C, Nagy A, Nakatsuji N, Narwani K, Oh SK, Oh SK, Olson C, Otonkoski T, Pan F, Park IH, Pells S, Pera MF, Pereira LV, Qi O, Raj GS, Reubinoff B, Robins A, Robson P, Rossant J, Salekdeh GH, Schulz TC, Sermon K, Sheik Mohamed J, Shen H, Sherrer E, Sidhu K, Sivarajah S, Skottman H, Spits C, Stacey GN, Strehl R, Strelchenko N, Suemori H, Sun B, Suuronen R, Takahashi K, Tuuri T, Venu P, Verlinsky Y, Ward-van Oostwaard D, Weisenberger DJ, Wu Y, Yamanaka S, Young L, Zhou Q.

Nat Biotechnol. 2011 Nov 27;29(12):1132-44. doi: 10.1038/nbt.2051.

29.

A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors.

Niwa A, Heike T, Umeda K, Oshima K, Kato I, Sakai H, Suemori H, Nakahata T, Saito MK.

PLoS One. 2011;6(7):e22261. doi: 10.1371/journal.pone.0022261. Epub 2011 Jul 27.

30.

Alpha-fetoprotein-producing pancreatic cancer cells possess cancer stem cell characteristics.

Sasaki N, Ishii T, Kamimura R, Kajiwara M, Machimoto T, Nakatsuji N, Suemori H, Ikai I, Yasuchika K, Uemoto S.

Cancer Lett. 2011 Sep 28;308(2):152-61. doi: 10.1016/j.canlet.2011.04.023. Epub 2011 May 26. Erratum in: Cancer Lett. 2012 Oct 28;323(2):232.

PMID:
21616586
31.

Tissue-specific demethylation in CpG-poor promoters during cellular differentiation.

Nagae G, Isagawa T, Shiraki N, Fujita T, Yamamoto S, Tsutsumi S, Nonaka A, Yoshiba S, Matsusaka K, Midorikawa Y, Ishikawa S, Soejima H, Fukayama M, Suemori H, Nakatsuji N, Kume S, Aburatani H.

Hum Mol Genet. 2011 Jul 15;20(14):2710-21. doi: 10.1093/hmg/ddr170. Epub 2011 Apr 19.

PMID:
21505077
32.

Simple and highly efficient method for production of endothelial cells from human embryonic stem cells.

Tatsumi R, Suzuki Y, Sumi T, Sone M, Suemori H, Nakatsuji N.

Cell Transplant. 2011;20(9):1423-30. doi: 10.3727/096368910X547444. Epub 2010 Dec 22.

PMID:
21176397
33.

Cardiomyocytes develop from anterior primitive streak cells induced by β-catenin activation and the blockage of BMP signaling in hESCs.

Yamauchi K, Sumi T, Minami I, Otsuji TG, Kawase E, Nakatsuji N, Suemori H.

Genes Cells. 2010 Dec;15(12):1216-27. doi: 10.1111/j.1365-2443.2010.01455.x. Epub 2010 Nov 3.

34.

Neutrophil differentiation from human-induced pluripotent stem cells.

Morishima T, Watanabe K, Niwa A, Fujino H, Matsubara H, Adachi S, Suemori H, Nakahata T, Heike T.

J Cell Physiol. 2011 May;226(5):1283-91. doi: 10.1002/jcp.22456.

PMID:
20945397
35.

Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells.

Ohgushi M, Matsumura M, Eiraku M, Murakami K, Aramaki T, Nishiyama A, Muguruma K, Nakano T, Suga H, Ueno M, Ishizaki T, Suemori H, Narumiya S, Niwa H, Sasai Y.

Cell Stem Cell. 2010 Aug 6;7(2):225-39. doi: 10.1016/j.stem.2010.06.018.

36.

Role of SOX2 in maintaining pluripotency of human embryonic stem cells.

Adachi K, Suemori H, Yasuda SY, Nakatsuji N, Kawase E.

Genes Cells. 2010 May;15(5):455-70. doi: 10.1111/j.1365-2443.2010.01400.x. Epub 2010 Apr 9.

37.

Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells.

International Stem Cell Initiative Consortium, Akopian V, Andrews PW, Beil S, Benvenisty N, Brehm J, Christie M, Ford A, Fox V, Gokhale PJ, Healy L, Holm F, Hovatta O, Knowles BB, Ludwig TE, McKay RD, Miyazaki T, Nakatsuji N, Oh SK, Pera MF, Rossant J, Stacey GN, Suemori H.

In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):247-58. doi: 10.1007/s11626-010-9297-z. Epub 2010 Feb 26.

38.

Alpha-fetoprotein producing cells act as cancer progenitor cells in human cholangiocarcinoma.

Ishii T, Yasuchika K, Suemori H, Nakatsuji N, Ikai I, Uemoto S.

Cancer Lett. 2010 Aug 1;294(1):25-34. doi: 10.1016/j.canlet.2010.01.019. Epub 2010 Feb 10.

PMID:
20149523
39.

Efficient integration of transgenes into a defined locus in human embryonic stem cells.

Sakurai K, Shimoji M, Tahimic CG, Aiba K, Kawase E, Hasegawa K, Amagai Y, Suemori H, Nakatsuji N.

Nucleic Acids Res. 2010 Apr;38(7):e96. doi: 10.1093/nar/gkp1234. Epub 2010 Jan 13.

40.

In vitro hepatic maturation of human embryonic stem cells by using a mesenchymal cell line derived from murine fetal livers.

Ishii T, Yasuchika K, Fukumitsu K, Kawamoto T, Kawamura-Saitoh M, Amagai Y, Ikai I, Uemoto S, Kawase E, Suemori H, Nakatsuji N.

Cell Tissue Res. 2010 Mar;339(3):505-12. doi: 10.1007/s00441-009-0906-7. Epub 2009 Dec 30.

PMID:
20041263
41.

Cryopreservation of primate embryonic stem cells with chemically-defined solution without Me2SO.

Nishigaki T, Teramura Y, Suemori H, Iwata H.

Cryobiology. 2010 Apr;60(2):159-64. doi: 10.1016/j.cryobiol.2009.10.007. Epub 2009 Oct 24.

PMID:
19857481
42.

Gene targeting in human pluripotent stem cells with adeno-associated virus vectors.

Mitsui K, Suzuki K, Aizawa E, Kawase E, Suemori H, Nakatsuji N, Mitani K.

Biochem Biophys Res Commun. 2009 Oct 30;388(4):711-7. doi: 10.1016/j.bbrc.2009.08.075. Epub 2009 Aug 18.

PMID:
19695233
43.

Establishment of a cell line derived from a mouse fetal liver that has the characteristic to promote the hepatic maturation of mouse embryonic stem cells by a coculture method.

Fukumitsu K, Ishii T, Yasuchika K, Amagai Y, Kawamura-Saito M, Kawamoto T, Kawase E, Suemori H, Nakatsuji N, Ikai I, Uemoto S.

Tissue Eng Part A. 2009 Dec;15(12):3847-56. doi: 10.1089/ten.TEA.2009.0357.

PMID:
19558317
44.

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.

Yamauchi K, Hasegawa K, Chuma S, Nakatsuji N, Suemori H.

PLoS One. 2009;4(4):e5338. doi: 10.1371/journal.pone.0005338. Epub 2009 Apr 28.

45.

Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells.

Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, Takahashi K, Homma K, Oyamada N, Inuzuka M, Sonoyama T, Ebihara K, Tamura N, Itoh H, Suemori H, Nakatsuji N, Okano H, Yamanaka S, Nakao K.

FEBS Lett. 2009 Mar 18;583(6):1029-33. doi: 10.1016/j.febslet.2009.02.031. Epub 2009 Feb 27.

46.

Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors.

Suzuki K, Mitsui K, Aizawa E, Hasegawa K, Kawase E, Yamagishi T, Shimizu Y, Suemori H, Nakatsuji N, Mitani K.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13781-6. doi: 10.1073/pnas.0806976105. Epub 2008 Sep 3.

47.

Recombinant human laminin isoforms can support the undifferentiated growth of human embryonic stem cells.

Miyazaki T, Futaki S, Hasegawa K, Kawasaki M, Sanzen N, Hayashi M, Kawase E, Sekiguchi K, Nakatsuji N, Suemori H.

Biochem Biophys Res Commun. 2008 Oct 10;375(1):27-32. doi: 10.1016/j.bbrc.2008.07.111. Epub 2008 Aug 12.

PMID:
18675790
48.

Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling.

Sumi T, Tsuneyoshi N, Nakatsuji N, Suemori H.

Development. 2008 Sep;135(17):2969-79. doi: 10.1242/dev.021121. Epub 2008 Jul 30.

49.

Effects of extracellular matrixes and growth factors on the hepatic differentiation of human embryonic stem cells.

Ishii T, Fukumitsu K, Yasuchika K, Adachi K, Kawase E, Suemori H, Nakatsuji N, Ikai I, Uemoto S.

Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G313-21. doi: 10.1152/ajpgi.00072.2008. Epub 2008 Jun 5.

50.

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells.

Tsuneyoshi N, Sumi T, Onda H, Nojima H, Nakatsuji N, Suemori H.

Biochem Biophys Res Commun. 2008 Mar 21;367(4):899-905. doi: 10.1016/j.bbrc.2007.12.189. Epub 2008 Jan 14.

PMID:
18194669

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