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Items: 33

1.

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.

Coutinho de Almeida R, Ramos YFM, Mahfouz A, den Hollander W, Lakenberg N, Houtman E, van Hoolwerff M, Suchiman HED, Rodríguez Ruiz A, Slagboom PE, Mei H, Kiełbasa SM, Nelissen RGHH, Reinders M, Meulenbelt I.

Ann Rheum Dis. 2019 Feb;78(2):270-277. doi: 10.1136/annrheumdis-2018-213882. Epub 2018 Dec 1.

2.

MS-based proteomics: a metrological sound and robust alternative for apolipoprotein E phenotyping in a multiplexed test.

Ruhaak LR, Smit NPM, Suchiman HED, Pieterse MM, Romijn FPHTM, Beekman M, Cobbaert CM.

Clin Chem Lab Med. 2018 Sep 21. pii: /j/cclm.ahead-of-print/cclm-2018-0782/cclm-2018-0782.xml. doi: 10.1515/cclm-2018-0782. [Epub ahead of print] No abstract available.

PMID:
30240356
3.

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells.

Roost MS, Slieker RC, Bialecka M, van Iperen L, Gomes Fernandes MM, He N, Suchiman HED, Szuhai K, Carlotti F, de Koning EJP, Mummery CL, Heijmans BT, Chuva de Sousa Lopes SM.

Nat Commun. 2017 Oct 13;8(1):908. doi: 10.1038/s41467-017-01077-3.

4.

Small nucleoli are a cellular hallmark of longevity.

Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, Späth M, Suchiman HED, Müller RU, Slagboom PE, Partridge L, Antebi A.

Nat Commun. 2017 Aug 30;8:16083. doi: 10.1038/ncomms16083.

5.

Short telomere length is associated with impaired cognitive performance in European ancestry cohorts.

Hägg S, Zhan Y, Karlsson R, Gerritsen L, Ploner A, van der Lee SJ, Broer L, Deelen J, Marioni RE, Wong A, Lundquist A, Zhu G, Hansell NK, Sillanpää E, Fedko IO, Amin NA, Beekman M, de Craen AJM, Degerman S, Harris SE, Kan KJ, Martin-Ruiz CM, Montgomery GW; NeuroCHARGE Cognitive Working Group, Adolfsson AN, Reynolds CA, Samani NJ, Suchiman HED, Viljanen A, von Zglinicki T, Wright MJ, Hottenga JJ, Boomsma DI, Rantanen T, Kaprio JA, Nyholt DR, Martin NG, Nyberg L, Adolfsson R, Kuh D, Starr JM, Deary IJ, Slagboom PE, van Duijn CM, Codd V, Pedersen NL.

Transl Psychiatry. 2017 Apr 18;7(4):e1100. doi: 10.1038/tp.2017.73.

6.

Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice.

Zwamborn RA, Slieker RC, Mulder PC, Zoetemelk I, Verschuren L, Suchiman HE, Toet KH, Droog S, Slagboom PE, Kooistra T, Kleemann R, Heijmans BT.

Sci Rep. 2017 Mar 3;7:43261. doi: 10.1038/srep43261.

7.

Disease variants alter transcription factor levels and methylation of their binding sites.

Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium, Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT.

Nat Genet. 2017 Jan;49(1):131-138. doi: 10.1038/ng.3721. Epub 2016 Dec 5.

PMID:
27918535
8.

Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process.

Bacalini MG, Deelen J, Pirazzini C, De Cecco M, Giuliani C, Lanzarini C, Ravaioli F, Marasco E, van Heemst D, Suchiman HED, Slieker R, Giampieri E, Recchioni R, Marcheselli F, Salvioli S, Vitale G, Olivieri F, Spijkerman AMW, Dollé MET, Sedivy JM, Castellani G, Franceschi C, Slagboom PE, Garagnani P.

J Gerontol A Biol Sci Med Sci. 2017 Aug 1;72(8):1015-1023. doi: 10.1093/gerona/glw185. Erratum in: J Gerontol A Biol Sci Med Sci. 2017 May 1;72(5):729.

9.

Genetic and environmental influences interact with age and sex in shaping the human methylome.

van Dongen J, Nivard MG, Willemsen G, Hottenga JJ, Helmer Q, Dolan CV, Ehli EA, Davies GE, van Iterson M, Breeze CE, Beck S; BIOS Consortium, Suchiman HE, Jansen R, van Meurs JB, Heijmans BT, Slagboom PE, Boomsma DI.

Nat Commun. 2016 Apr 7;7:11115. doi: 10.1038/ncomms11115.

10.

Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.

van den Akker EB, Pitts SJ, Deelen J, Moed MH, Potluri S, van Rooij J, Suchiman HE, Lakenberg N, de Dijcker WJ, Uitterlinden AG, Kraaij R, Hofman A, de Craen AJ, Houwing-Duistermaat JJ, van Ommen GJ; Genome of The Netherlands Consortium, Cox DR, van Meurs JB, Beekman M, Reinders MJ, Slagboom PE.

Blood. 2016 Mar 17;127(11):1512-5. doi: 10.1182/blood-2015-12-685925. Epub 2016 Jan 29. No abstract available.

11.

DNA Methylation Landscapes of Human Fetal Development.

Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT, Chuva de Sousa Lopes SM.

PLoS Genet. 2015 Oct 22;11(10):e1005583. doi: 10.1371/journal.pgen.1005583. eCollection 2015 Oct.

12.

Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER.

Suchiman HE, Slieker RC, Kremer D, Slagboom PE, Heijmans BT, Tobi EW.

Front Genet. 2015 Sep 17;6:287. doi: 10.3389/fgene.2015.00287. eCollection 2015.

13.

Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome.

Tobi EW, Slieker RC, Stein AD, Suchiman HE, Slagboom PE, van Zwet EW, Heijmans BT, Lumey LH.

Int J Epidemiol. 2015 Aug;44(4):1211-23. doi: 10.1093/ije/dyv043. Epub 2015 May 5.

14.

Transcriptional associations of osteoarthritis-mediated loss of epigenetic control in articular cartilage.

den Hollander W, Ramos YF, Bomer N, Elzinga S, van der Breggen R, Lakenberg N, de Dijcker WJ, Suchiman HE, Duijnisveld BJ, Houwing-Duistermaat JJ, Slagboom PE, Bos SD, Nelissen RG, Meulenbelt I.

Arthritis Rheumatol. 2015 May;67(8):2108-16. doi: 10.1002/art.39162.

15.

A common mineralocorticoid receptor polymorphism (I180V) interacts with life events in relation to perfectionism in eating disorders: a pilot study.

Slof-Op't Landt MC, DeRijk RH, van Son GE, Suchiman HE, Meulenbelt I, Slagboom PE, Van Furth EF.

Eur Eat Disord Rev. 2014 Nov;22(6):423-9. doi: 10.1002/erv.2319. Epub 2014 Sep 14.

PMID:
25220664
16.

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers.

Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, van Duijn CM, Jukema JW, Houwing-Duistermaat JJ, Samani NJ, Slagboom PE.

Int J Epidemiol. 2014 Jun;43(3):878-86. doi: 10.1093/ije/dyt267. Epub 2014 Jan 14.

17.

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array.

Slieker RC, Bos SD, Goeman JJ, Bovée JV, Talens RP, van der Breggen R, Suchiman HE, Lameijer EW, Putter H, van den Akker EB, Zhang Y, Jukema JW, Slagboom PE, Meulenbelt I, Heijmans BT.

Epigenetics Chromatin. 2013 Aug 6;6(1):26. doi: 10.1186/1756-8935-6-26.

18.

Identification of seven loci affecting mean telomere length and their association with disease.

Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Broer L, Nyholt DR, Mateo Leach I, Salo P, Hägg S, Matthews MK, Palmen J, Norata GD, O'Reilly PF, Saleheen D, Amin N, Balmforth AJ, Beekman M, de Boer RA, Böhringer S, Braund PS, Burton PR, de Craen AJ, Denniff M, Dong Y, Douroudis K, Dubinina E, Eriksson JG, Garlaschelli K, Guo D, Hartikainen AL, Henders AK, Houwing-Duistermaat JJ, Kananen L, Karssen LC, Kettunen J, Klopp N, Lagou V, van Leeuwen EM, Madden PA, Mägi R, Magnusson PK, Männistö S, McCarthy MI, Medland SE, Mihailov E, Montgomery GW, Oostra BA, Palotie A, Peters A, Pollard H, Pouta A, Prokopenko I, Ripatti S, Salomaa V, Suchiman HE, Valdes AM, Verweij N, Viñuela A, Wang X, Wichmann HE, Widen E, Willemsen G, Wright MJ, Xia K, Xiao X, van Veldhuisen DJ, Catapano AL, Tobin MD, Hall AS, Blakemore AI, van Gilst WH, Zhu H; CARDIoGRAM consortium, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Talmud PJ, Pedersen NL, Perola M, Ouwehand W, Kaprio J, Martin NG, van Duijn CM, Hovatta I, Gieger C, Metspalu A, Boomsma DI, Jarvelin MR, Slagboom PE, Thompson JR, Spector TD, van der Harst P, Samani NJ.

Nat Genet. 2013 Apr;45(4):422-7, 427e1-2. doi: 10.1038/ng.2528.

19.

The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection.

Willemsen G, Vink JM, Abdellaoui A, den Braber A, van Beek JH, Draisma HH, van Dongen J, van 't Ent D, Geels LM, van Lien R, Ligthart L, Kattenberg M, Mbarek H, de Moor MH, Neijts M, Pool R, Stroo N, Kluft C, Suchiman HE, Slagboom PE, de Geus EJ, Boomsma DI.

Twin Res Hum Genet. 2013 Feb;16(1):271-81. doi: 10.1017/thg.2012.140. Epub 2013 Jan 8.

20.

Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs.

Talens RP, Christensen K, Putter H, Willemsen G, Christiansen L, Kremer D, Suchiman HE, Slagboom PE, Boomsma DI, Heijmans BT.

Aging Cell. 2012 Aug;11(4):694-703. doi: 10.1111/j.1474-9726.2012.00835.x. Epub 2012 Jun 4.

21.

Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.

Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Jacobsen R, Suchiman HE, de Craen AJ, Westendorp RG, Schreiber S, Stevnsner T, Bohr VA, Slagboom PE, Nebel A, Vaupel JW, Christensen K, McGue M, Christiansen L.

Exp Gerontol. 2012 May;47(5):379-87. doi: 10.1016/j.exger.2012.02.010. Epub 2012 Mar 3.

22.

Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.

Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Suchiman HE, Jacobsen R, McGue M, Stevnsner T, Bohr VA, de Craen AJ, Westendorp RG, Schreiber S, Slagboom PE, Nebel A, Vaupel JW, Christensen K, Christiansen L.

Age (Dordr). 2013 Apr;35(2):487-500. doi: 10.1007/s11357-011-9373-7. Epub 2012 Jan 12.

23.

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE.

Aging Cell. 2011 Aug;10(4):686-98. doi: 10.1111/j.1474-9726.2011.00705.x. Epub 2011 May 6.

24.

Influence of candidate genes on attention problems in children: a longitudinal study.

van Beijsterveldt CE, Middeldorp CM, Slof-Op't Landt MC, Bartels M, Hottenga JJ, Suchiman HE, Slagboom PE, Boomsma DI.

Behav Genet. 2011 Jan;41(1):155-64. doi: 10.1007/s10519-010-9406-5. Epub 2010 Oct 30.

25.

Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity.

Beekman M, Nederstigt C, Suchiman HE, Kremer D, van der Breggen R, Lakenberg N, Alemayehu WG, de Craen AJ, Westendorp RG, Boomsma DI, de Geus EJ, Houwing-Duistermaat JJ, Heijmans BT, Slagboom PE.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18046-9. doi: 10.1073/pnas.1003540107. Epub 2010 Oct 4.

26.

Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

Middeldorp CM, Slof-Op 't Landt MC, Medland SE, van Beijsterveldt CE, Bartels M, Willemsen G, Hottenga JJ, de Geus EJ, Suchiman HE, Dolan CV, Neale MC, Slagboom PE, Boomsma DI.

Genes Brain Behav. 2010 Oct;9(7):808-16. doi: 10.1111/j.1601-183X.2010.00619.x. Epub 2010 Aug 12.

27.

The Netherlands Twin Register biobank: a resource for genetic epidemiological studies.

Willemsen G, de Geus EJ, Bartels M, van Beijsterveldt CE, Brooks AI, Estourgie-van Burk GF, Fugman DA, Hoekstra C, Hottenga JJ, Kluft K, Meijer P, Montgomery GW, Rizzu P, Sondervan D, Smit AB, Spijker S, Suchiman HE, Tischfield JA, Lehner T, Slagboom PE, Boomsma DI.

Twin Res Hum Genet. 2010 Jun;13(3):231-45. doi: 10.1375/twin.13.3.231.

PMID:
20477721
28.

Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a Ghanaian population.

Kuningas M, May L, Tamm R, van Bodegom D, van den Biggelaar AH, Meij JJ, Frölich M, Ziem JB, Suchiman HE, Metspalu A, Slagboom PE, Westendorp RG.

PLoS One. 2009 Nov 11;4(11):e7795. doi: 10.1371/journal.pone.0007795.

29.

Vitamin D receptor gene polymorphisms have negligible effect on human height.

Macgregor S, Hottenga JJ, Lind PA, Suchiman HE, Willemsen G, Slagboom PE, Montgomery GW, Martin NG, Visscher PM, Boomsma DI.

Twin Res Hum Genet. 2008 Oct;11(5):488-94. doi: 10.1375/twin.11.5.488.

PMID:
18828731
30.

Allelic variation at the C-reactive protein gene associates to both hand osteoarthritis severity and serum high sensitive C-reactive protein levels in the GARP study.

Bos SD, Suchiman HE, Kloppenburg M, Houwing-Duistermaat JJ, le Graverand MP, Seymour AB, Kroon HM, Slagboom PE, Meulenbelt I.

Ann Rheum Dis. 2008 Jun;67(6):877-9. Epub 2007 Nov 29.

PMID:
18055473
31.

Combined association and linkage analysis applied to the APOE locus.

Beekman M, Posthuma D, Heijmans BT, Lakenberg N, Suchiman HE, Snieder H, de Knijff P, Frants RR, van Ommen GJ, Kluft C, Vogler GP, Slagboom PE, Boomsma DI.

Genet Epidemiol. 2004 May;26(4):328-37.

PMID:
15095392
32.

Evidence for a QTL on chromosome 19 influencing LDL cholesterol levels in the general population.

Beekman M, Heijmans BT, Martin NG, Whitfield JB, Pedersen NL, DeFaire U, Snieder H, Lakenberg N, Suchiman HE, de Knijff P, Frants RR, van Ommen GJ, Kluft C, Vogler GP, Boomsma DI, Slagboom PE.

Eur J Hum Genet. 2003 Nov;11(11):845-50.

33.

A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer.

Heijmans BT, Boer JM, Suchiman HE, Cornelisse CJ, Westendorp RG, Kromhout D, Feskens EJ, Slagboom PE.

Cancer Res. 2003 Mar 15;63(6):1249-53.

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