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Items: 1 to 50 of 470

1.

Discovery and Development of N-[4-(l-Cyclobutylpiperidin-4-yloxy) phenyl]-2-(morpholin-4-yl) acetamide dihydrochloride (SUVN-G3031): A Novel, Potent, Selective and Orally Active Histamine H3 Receptor Inverse Agonist with Robust Wake-Promoting Activity.

Nirogi R, Shinde AK, Mohammed AR, Badange RK, Reballi V, Bandyala TR, Saraf SK, Bojja K, Manchineella S, Achanta PK, Kandukuri KK, Subramanian R, Benade V, Palacharla RC, Jayarajan P, Pandey S, Jasti V.

J Med Chem. 2019 Jan 10. doi: 10.1021/acs.jmedchem.8b01280. [Epub ahead of print]

PMID:
30629436
2.

Value of VKORC1 (-1639G>A) rs9923231 genotyping in predicting warfarin dose: A replication study in South Indian population.

Harikrishnan S, Koshy L, Subramanian R, Sanjay G, Vineeth CP, Nair AJ, Nair GM, Sudhakaran PR.

Indian Heart J. 2018 Dec;70 Suppl 3:S110-S115. doi: 10.1016/j.ihj.2018.07.006. Epub 2018 Jul 19.

3.

First reported case of Human Parechovirus encephalitis in an adult patient complicated by Refractory Status Epilepticus.

Chimunda T, Subramanian R, Smith J, Mahony A.

IDCases. 2018 Dec 3;15:e00475. doi: 10.1016/j.idcr.2018.e00475. eCollection 2019.

4.

An integrated process for the production of 1,3-propanediol, lactate and 3-hydroxypropionic acid by an engineered Lactobacillus reuteri.

Suppuram P, Ramakrishnan GG, Subramanian R.

Biosci Biotechnol Biochem. 2018 Dec 22:1-8. doi: 10.1080/09168451.2018.1559720. [Epub ahead of print]

PMID:
30582401
5.

Beating the Odds: A Full-Term Delivery After Liver Transplantation of a Pregnant Hyperthyroid Patient at 19 Weeks' Gestation for Propylthiouracil-Induced Acute Liver Failure.

Bartnik CM, Maheshwari RN, Subramanian RM.

Transplant Proc. 2018 Dec;50(10):3995-3999. doi: 10.1016/j.transproceed.2018.06.046. Epub 2018 Jun 30.

PMID:
30577302
6.

Factors Affecting Growth Kinetics and Spontaneous Metastasis in the B16F10 Syngeneic Murine Melanoma Model.

Fowlkes N, Clemons K, Rider PJ, Subramanian R, Wakamatsu N, Langohr I, Kousoulas KG.

Comp Med. 2018 Dec 18. doi: 10.30802/AALAS-CM-18-000036. [Epub ahead of print]

PMID:
30563585
7.

Caring for the Critically Ill Alcoholic Liver Disease Patient: An Uphill Battle Worth Fighting.

Flynn MM, Subramanian RM.

Crit Care Med. 2019 Jan;47(1):123-124. doi: 10.1097/CCM.0000000000003488. No abstract available.

PMID:
30557242
8.

Self-Assembly of a Designed Nucleoprotein Architecture through Multimodal Interactions.

Subramanian RH, Smith SJ, Alberstein RG, Bailey JB, Zhang L, Cardone G, Suominen L, Chami M, Stahlberg H, Baker TS, Tezcan FA.

ACS Cent Sci. 2018 Nov 28;4(11):1578-1586. doi: 10.1021/acscentsci.8b00745. Epub 2018 Nov 15.

9.

Acute Liver Failure.

Rajaram P, Subramanian R.

Semin Respir Crit Care Med. 2018 Oct;39(5):513-522. doi: 10.1055/s-0038-1673372. Epub 2018 Nov 28.

PMID:
30485882
10.

Critical Care Considerations in Liver Failure.

Barjaktarevic I, Subramanian R, Wang T.

Semin Respir Crit Care Med. 2018 Oct;39(5):511-512. doi: 10.1055/s-0038-1673371. Epub 2018 Nov 28.

PMID:
30485881
11.

Quantifying high-resolution spatial variations and local source impacts of urban ultrafine particle concentrations.

Saha PK, Zimmerman N, Malings C, Hauryliuk A, Li Z, Snell L, Subramanian R, Lipsky E, Apte JS, Robinson AL, Presto AA.

Sci Total Environ. 2019 Mar 10;655:473-481. doi: 10.1016/j.scitotenv.2018.11.197. Epub 2018 Nov 14.

PMID:
30476828
12.

Composition, structure and function of the eukaryotic flagellum distal tip.

Croft JT, Zabeo D, Subramanian R, Höög JL.

Essays Biochem. 2018 Dec 7;62(6):815-828. doi: 10.1042/EBC20180032. Print 2018 Dec 7. Review.

13.

Extracorporeal Devices.

Kandiah PA, Subramanian RM.

Crit Care Clin. 2019 Jan;35(1):135-150. doi: 10.1016/j.ccc.2018.08.003. Review.

PMID:
30447776
14.

Aerosol Optical Properties and Climate Implications of Emissions from Traditional and Improved Cookstoves.

Saliba G, Subramanian R, Bilsback K, L'Orange C, Volckens J, Johnson M, Robinson AL.

Environ Sci Technol. 2018 Nov 20;52(22):13647-13656. doi: 10.1021/acs.est.8b05434. Epub 2018 Nov 8.

PMID:
30373367
15.

Transmission of Eastern Equine Encephalitis Virus from an Organ Donor to Three Transplant Recipients.

Pouch SM, Katugaha SB, Shieh WJ, Annambhotla P, Walker WL, Basavaraju SV, Jones J, Huynh T, Reagan-Steiner S, Bhatnagar J, Grimm K, Stramer SL, Gabel J, Lyon GM, Mehta AK, Kandiah P, Neujahr DC, Javidfar J, Subramanian RM, Parekh SM, Shah P, Cooper L, Psotka MA, Radcliffe R, Williams C, Zaki SR, Staples JE, Fischer M, Panella AJ, Lanciotti RS, Laven JJ, Kosoy O, Rabe IB, Gould CV; Eastern Equine Encephalitis Virus Transplant Transmission Investigation Team.

Clin Infect Dis. 2018 Oct 29. doi: 10.1093/cid/ciy923. [Epub ahead of print]

PMID:
30371754
16.

Geometry of antiparallel microtubule bundles regulates relative sliding and stalling by PRC1 and Kif4A.

Wijeratne S, Subramanian R.

Elife. 2018 Oct 24;7. pii: e32595. doi: 10.7554/eLife.32595.

17.

Frames of Mental Illness in an Indian Daily Newspaper.

Subramanian R.

Health Commun. 2018 Oct 19:1-10. doi: 10.1080/10410236.2018.1536948. [Epub ahead of print]

PMID:
30339036
18.

Molecular characterization of the interaction of sialic acid with the periplasmic binding protein from Haemophilus ducreyi.

Gangi Setty T, Mowers JC, Hobbs AG, Maiya SP, Syed S, Munson RS Jr, Apicella MA, Subramanian R.

J Biol Chem. 2018 Dec 28;293(52):20073-20084. doi: 10.1074/jbc.RA118.005151. Epub 2018 Oct 12.

PMID:
30315109
19.

Adding to the Repertoire of Scoring Systems in Acute-on-Chronic Liver Failure: Will Simplicity Be Outdone by Complexity?

Rajaram P, Subramanian RM.

Crit Care Med. 2018 Nov;46(11):1875-1876. doi: 10.1097/CCM.0000000000003398. No abstract available.

PMID:
30312234
20.

Methane emissions from natural gas production sites in the United States: Data synthesis and national estimate.

Omara M, Zimmerman N, Sullivan MR, Li X, Ellis A, Cesa R, Subramanian R, Presto AA, Robinson AL.

Environ Sci Technol. 2018 Sep 26. doi: 10.1021/acs.est.8b03535. [Epub ahead of print]

PMID:
30256618
21.

Uncoupling Warburg effect and stemness in CD133+ve cancer stem cells from Saos-2 (osteosarcoma) cell line under hypoxia.

Koka P, Mundre RS, Rangarajan R, Chandramohan Y, Subramanian RK, Dhanasekaran A.

Mol Biol Rep. 2018 Aug 20. doi: 10.1007/s11033-018-4309-2. [Epub ahead of print]

PMID:
30128626
22.

Promoter expression of HERV-K (HML-2) provirus-derived sequences is related to LTR sequence variation and polymorphic transcription factor binding sites.

Montesion M, Williams ZH, Subramanian RP, Kuperwasser C, Coffin JM.

Retrovirology. 2018 Aug 20;15(1):57. doi: 10.1186/s12977-018-0441-2.

23.

Role of anesthesiologist in ex utero intrapartum treatment procedure: A case and review of anesthetic management.

Subramanian R, Mishra P, Subramaniam R, Bansal S.

J Anaesthesiol Clin Pharmacol. 2018 Apr-Jun;34(2):148-154. doi: 10.4103/joacp.JOACP_239_16. Review.

24.

The Firepower Sweep Test: A novel approach to cookstove laboratory testing.

Bilsback KR, Eilenberg SR, Good N, Heck L, Johnson M, Kodros JK, Lipsky EM, L'Orange C, Pierce JR, Robinson AL, Subramanian R, Tryner J, Wilson A, Volckens J.

Indoor Air. 2018 Nov;28(6):936-949. doi: 10.1111/ina.12497. Epub 2018 Sep 19.

PMID:
30099773
25.

Patients on levothyroxine replacement in the community: association between hypothyroidism symptoms, co-morbidities and their quality of life.

Tan NC, Chew RQ, Subramanian RC, Sankari U, Koh YLE, Cho LW.

Fam Pract. 2018 Jul 13. doi: 10.1093/fampra/cmy064. [Epub ahead of print]

PMID:
30010746
26.

SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency.

Connolly B, Isaacs C, Cheng L, Asrani KH, Subramanian RR.

J Nucleic Acids. 2018 Jun 13;2018:8247935. doi: 10.1155/2018/8247935. eCollection 2018.

27.

Author Correction: Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks.

Zhang L, Bailey JB, Subramanian RH, Groisman A, Tezcan FA.

Nature. 2018 Aug;560(7719):E31. doi: 10.1038/s41586-018-0283-z.

28.

Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae.

Manjunath L, Guntupalli SR, Currie MJ, North RA, Dobson RCJ, Nayak V, Subramanian R.

Acta Crystallogr F Struct Biol Commun. 2018 Jul 1;74(Pt 7):431-440. doi: 10.1107/S2053230X18008543. Epub 2018 Jun 28.

PMID:
29969107
29.

Arginase I mRNA therapy - a novel approach to rescue arginase 1 enzyme deficiency.

Asrani KH, Cheng L, Cheng CJ, Subramanian RR.

RNA Biol. 2018;15(7):914-922. doi: 10.1080/15476286.2018.1475178. Epub 2018 Jul 24.

PMID:
29923457
30.

Rapid synthesis of polysubstituted phenanthridines from simple aliphatic/aromatic nitriles and iodo arenes via Pd(ii) catalyzed domino C-C/C-C/C-N bond formation.

Jaiswal Y, Kumar Y, Pal J, Subramanian R, Kumar A.

Chem Commun (Camb). 2018 Jun 26;54(52):7207-7210. doi: 10.1039/c8cc03556c.

PMID:
29897059
31.

Influence of milling on the nutritional composition of bran from different rice varieties.

Kalpanadevi C, Singh V, Subramanian R.

J Food Sci Technol. 2018 Jun;55(6):2259-2269. doi: 10.1007/s13197-018-3143-9. Epub 2018 Apr 3.

PMID:
29892126
32.

The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis.

Bajaj JS, Tandon P, O'Leary JG, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai JC, Fallon M, Thuluvath P, Vargas HE, Subramanian RM, Thacker LR, Reddy KR.

Am J Gastroenterol. 2018 Sep;113(9):1339-1344. doi: 10.1038/s41395-018-0119-3. Epub 2018 Jun 8.

PMID:
29880972
33.

SUVN-502, a novel, potent, pure, and orally active 5-HT6 receptor antagonist: pharmacological, behavioral, and neurochemical characterization.

Nirogi R, Abraham R, Benade V, Medapati RB, Jayarajan P, Bhyrapuneni G, Muddana N, Mekala VR, Subramanian R, Shinde A, Kambhampati R, Jasti V.

Behav Pharmacol. 2019 Feb;30(1):16-35. doi: 10.1097/FBP.0000000000000414.

PMID:
29847336
34.

mRNA treatment produces sustained expression of enzymatically active human ADAMTS13 in mice.

Liu-Chen S, Connolly B, Cheng L, Subramanian RR, Han Z.

Sci Rep. 2018 May 18;8(1):7859. doi: 10.1038/s41598-018-26298-4.

35.

Synthesis, Structure-Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT4 Receptor Partial Agonists.

Nirogi R, Mohammed AR, Shinde AK, Gagginapally SR, Kancharla DM, Middekadi VR, Bogaraju N, Ravella SR, Singh P, Birangal SR, Subramanian R, Palacharla RC, Benade V, Muddana N, Jayarajan P.

J Med Chem. 2018 Jun 14;61(11):4993-5008. doi: 10.1021/acs.jmedchem.8b00457. Epub 2018 May 31.

PMID:
29763304
36.

Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks.

Zhang L, Bailey JB, Subramanian RH, Groisman A, Tezcan FA.

Nature. 2018 May;557(7703):86-91. doi: 10.1038/s41586-018-0057-7. Epub 2018 May 2. Erratum in: Nature. 2018 Jul 4;:.

37.

Differential growth of Mycobacterium leprae strains (SNP genotypes) in armadillos.

Sharma R, Singh P, Pena M, Subramanian R, Chouljenko V, Kim J, Kim N, Caskey J, Baudena MA, Adams LB, Truman RW.

Infect Genet Evol. 2018 Aug;62:20-26. doi: 10.1016/j.meegid.2018.04.017. Epub 2018 Apr 14.

PMID:
29665434
38.

Care of the Critically Ill Cirrhotic: It Is Not a Losing Battle.

Rajaram P, Subramanian RM.

Crit Care Med. 2018 May;46(5):813-814. doi: 10.1097/CCM.0000000000003034. No abstract available.

PMID:
29652706
39.

Management of Acute Liver Failure in the Intensive Care Unit Setting.

Rajaram P, Subramanian R.

Clin Liver Dis. 2018 May;22(2):403-408. doi: 10.1016/j.cld.2018.01.013. Epub 2018 Feb 23. Review.

PMID:
29605074
40.

Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA.

Asrani KH, Farelli JD, Stahley MR, Miller RL, Cheng CJ, Subramanian RR, Brown JM.

RNA Biol. 2018;15(6):756-762. doi: 10.1080/15476286.2018.1450054. Epub 2018 Mar 26.

41.

Clinical Pharmacokinetics and Pharmacodynamics of Etelcalcetide, a Novel Calcimimetic for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis.

Wu B, Melhem M, Subramanian R, Chen P, Jaramilla Sloey B, Fouqueray B, Hock MB, Skiles GL, Chow AT, Lee E.

J Clin Pharmacol. 2018 Jun;58(6):717-726. doi: 10.1002/jcph.1090. Epub 2018 Mar 13. Review.

PMID:
29534286
42.

Identification of multiple isomeric core chitobiose-modified high-mannose and paucimannose N-glycans in the planarian Schmidtea mediterranea.

Subramanian SP, Babu P, Palakodeti D, Subramanian R.

J Biol Chem. 2018 May 4;293(18):6707-6720. doi: 10.1074/jbc.RA117.000782. Epub 2018 Feb 23.

43.

Effects of substrate binding site residue substitutions of xynA from Bacillus amyloliquefaciens on substrate specificity.

Prajapati AS, Pawar VA, Panchal KJ, Sudhir AP, Dave BR, Patel DH, Subramanian RB.

BMC Biotechnol. 2018 Feb 13;18(1):9. doi: 10.1186/s12896-018-0420-7.

44.

Leveraging Rational Protein Engineering to Improve mRNA Therapeutics.

Farelli JD, Asrani KH, Isaacs C, deBear JS, Stahley MR, Shah A, Lasaro MA, Cheng CJ, Subramanian RR.

Nucleic Acid Ther. 2018 Apr;28(2):74-85. doi: 10.1089/nat.2017.0697. Epub 2018 Feb 13.

PMID:
29437538
45.

Molecular and biochemical characterization of a thermostable keratinase from Bacillus altitudinis RBDV1.

Pawar VA, Prajapati AS, Akhani RC, Patel DH, Subramanian RB.

3 Biotech. 2018 Feb;8(2):107. doi: 10.1007/s13205-018-1130-5. Epub 2018 Feb 2.

PMID:
29430368
46.

G6PC mRNA Therapy Positively Regulates Fasting Blood Glucose and Decreases Liver Abnormalities in a Mouse Model of Glycogen Storage Disease 1a.

Roseman DS, Khan T, Rajas F, Jun LS, Asrani KH, Isaacs C, Farelli JD, Subramanian RR.

Mol Ther. 2018 Mar 7;26(3):814-821. doi: 10.1016/j.ymthe.2018.01.006. Epub 2018 Jan 31.

47.

NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis.

O'Leary JG, Reddy KR, Garcia-Tsao G, Biggins SW, Wong F, Fallon MB, Subramanian RM, Kamath PS, Thuluvath P, Vargas HE, Maliakkal B, Tandon P, Lai J, Thacker LR, Bajaj JS.

Hepatology. 2018 Jun;67(6):2367-2374. doi: 10.1002/hep.29773. Epub 2018 Apr 19.

PMID:
29315693
48.

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development.

Zheng J, Xin Y, Zhang J, Subramanian R, Murray BP, Whitney JA, Warr MR, Ling J, Moorehead L, Kwan E, Hemenway J, Smith BJ, Silverman JA.

Drug Metab Dispos. 2018 Mar;46(3):237-247. doi: 10.1124/dmd.117.078899. Epub 2018 Jan 8.

PMID:
29311136
49.

'The efficacy of extracorporeal liver support with molecular adsorbent recirculating system in severe drug-induced liver injury'.

Eapen J, Ayoola R, Subramanian RM.

Oxf Med Case Reports. 2018 Jan 2;2018(1):omx077. doi: 10.1093/omcr/omx077. eCollection 2018 Jan.

50.

Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort.

Bajaj JS, Rajender Reddy K, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Fallon M, Maliakkal B, Lai J, Vargas HE, Subramanian RM, Thuluvath P, Thacker LR, O'Leary JG.

Am J Gastroenterol. 2018 Apr;113(4):556-563. doi: 10.1038/ajg.2017.471. Epub 2017 Dec 19.

PMID:
29257141

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