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Items: 1 to 50 of 137

1.

PlateDesigner: a web-based application for the design of microplate experiments.

Suprun M, Suárez-Fariñas M.

Bioinformatics. 2018 Oct 9. doi: 10.1093/bioinformatics/bty853. [Epub ahead of print]

PMID:
30304481
2.

Integrating the skin and blood transcriptomes and serum proteome in hidradenitis suppurativa reveals complement dysregulation and a plasma cell signature.

Hoffman LK, Tomalin LE, Schultz G, Howell MD, Anandasabapathy N, Alavi A, Suárez-Fariñas M, Lowes MA.

PLoS One. 2018 Sep 28;13(9):e0203672. doi: 10.1371/journal.pone.0203672. eCollection 2018.

3.

Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen-Specific Challenge.

Patel NP, Vukmanovic-Stejic M, Suarez-Farinas M, Chambers ES, Sandhu D, Fuentes-Duculan J, Mabbott NA, Rustin MHA, Krueger J, Akbar AN.

J Infect Dis. 2018 Sep 22;218(suppl_2):S88-S98. doi: 10.1093/infdis/jiy420.

4.

Dupilumab progressively improves systemic and cutaneous abnormalities in atopic dermatitis patients.

Guttman-Yassky E, Bissonnette R, Ungar B, Suárez-Fariñas M, Ardeleanu M, Esaki H, Suprun M, Estrada Y, Xu H, Peng X, Silverberg JI, Menter A, Krueger JG, Zhang R, Chaudhry U, Swanson B, Graham NMH, Pirozzi G, Yancopoulos GD, Hamilton JDD.

J Allergy Clin Immunol. 2018 Sep 5. pii: S0091-6749(18)31266-1. doi: 10.1016/j.jaci.2018.08.022. [Epub ahead of print]

5.

Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases.

Michlmayr D, Pak TR, Rahman AH, Amir ED, Kim EY, Kim-Schulze S, Suprun M, Stewart MG, Thomas GP, Balmaseda A, Wang L, Zhu J, Suaréz-Fariñas M, Wolinsky SM, Kasarskis A, Harris E.

Mol Syst Biol. 2018 Aug 27;14(8):e7862. doi: 10.15252/msb.20177862.

6.

A new Luminex-based peptide assay to identify reactivity to baked, fermented, and whole milk.

Sackesen C, Suárez-Fariñas M, Sillva R, Lin J, Schmidt S, Getts R, Gimenez G, Yilmaz EA, Cavkaytar O, Buyuktiryaki B, Soyer O, Grishina G, Sampson HA.

Allergy. 2018 Jul 29. doi: 10.1111/all.13581. [Epub ahead of print]

PMID:
30058196
7.

Association of Inadequately Controlled Disease and Disease Severity With Patient-Reported Disease Burden in Adults With Atopic Dermatitis.

Simpson EL, Guttman-Yassky E, Margolis DJ, Feldman SR, Qureshi A, Hata T, Mastey V, Wei W, Eckert L, Chao J, Arnold RJG, Yu T, Vekeman F, Suárez-Fariñas M, Gadkari A.

JAMA Dermatol. 2018 Aug 1;154(8):903-912. doi: 10.1001/jamadermatol.2018.1572.

8.

Author Correction: The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins.

Brunner PM, Suárez-Fariñas M, He H, Malik K, Wen HC, Gonzalez J, Chan TC, Estrada Y, Zheng X, Khattri S, Dattola A, Krueger JG, Guttman-Yassky E.

Sci Rep. 2018 May 29;8(1):8439. doi: 10.1038/s41598-018-26378-5.

9.

A Method to Summarize Toxicity in Cancer Randomized Clinical Trials.

Carbini M, Suárez-Fariñas M, Maki RG.

Clin Cancer Res. 2018 Oct 15;24(20):4968-4975. doi: 10.1158/1078-0432.CCR-17-3314. Epub 2018 May 8.

PMID:
29739789
10.

New methodologies to accurately assess circulating active transforming growth factor-β1 levels: implications for evaluating heart failure and the impact of left ventricular assist devices.

Mancini D, Monteagudo J, Suárez-Fariñas M, Bander J, Varshney R, Gonzalez J, Coller BS, Ahamed J.

Transl Res. 2018 Feb;192:15-29. doi: 10.1016/j.trsl.2017.10.006. Epub 2017 Nov 5.

11.

Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation.

Vukmanovic-Stejic M, Chambers ES, Suárez-Fariñas M, Sandhu D, Fuentes-Duculan J, Patel N, Agius E, Lacy KE, Turner CT, Larbi A, Birault V, Noursadeghi M, Mabbott NA, Rustin MHA, Krueger JG, Akbar AN.

J Allergy Clin Immunol. 2018 Sep;142(3):844-856. doi: 10.1016/j.jaci.2017.10.032. Epub 2017 Nov 17.

12.

Dust mite induces multiple polar T cell axes in human skin.

Malik K, Ungar B, Garcet S, Dutt R, Dickstein D, Zheng X, Xu H, Estrada YD, Suárez-Fariñas M, Shemer A, Krueger JG, Guttman-Yassky E.

Clin Exp Allergy. 2017 Dec;47(12):1648-1660. doi: 10.1111/cea.13040. Epub 2017 Nov 6.

PMID:
28977706
13.

Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment.

Kim J, Tomalin L, Lee J, Fitz LJ, Berstein G, Correa-da Rosa J, Garcet S, Lowes MA, Valdez H, Wolk R, Suarez-Farinas M, Krueger JG.

J Invest Dermatol. 2018 Feb;138(2):273-281. doi: 10.1016/j.jid.2017.08.040. Epub 2017 Sep 18.

PMID:
28927890
14.

The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins.

Brunner PM, Suárez-Fariñas M, He H, Malik K, Wen HC, Gonzalez J, Chan TC, Estrada Y, Zheng X, Khattri S, Dattola A, Krueger JG, Guttman-Yassky E.

Sci Rep. 2017 Aug 18;7(1):8707. doi: 10.1038/s41598-017-09207-z. Erratum in: Sci Rep. 2018 May 29;8(1):8439.

15.

Identification of unique proteomic signatures in allergic and non-allergic skin disease.

Wang J, Suárez-Fariñas M, Estrada Y, Parker ML, Greenlees L, Stephens G, Krueger J, Guttman-Yassky E, Howell MD.

Clin Exp Allergy. 2017 Nov;47(11):1456-1467. doi: 10.1111/cea.12979. Epub 2017 Aug 11.

PMID:
28703865
16.

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.

Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, Song-Zhao GX, Gulati N, Lowes MA, King SL, Quintana FJ, Lee YS, Krueger JG, Sarin KY, Yoon CH, Garraway L, Regev A, Shalek AK, Troyanskaya O, Anandasabapathy N.

Cell. 2017 Jun 29;170(1):127-141.e15. doi: 10.1016/j.cell.2017.06.016.

17.

Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis.

Guttman-Yassky E, Ungar B, Malik K, Dickstein D, Suprun M, Estrada YD, Xu H, Peng X, Oliva M, Todd D, Labuda T, Suarez-Farinas M, Bissonnette R.

J Allergy Clin Immunol. 2017 Oct;140(4):1032-1042.e13. doi: 10.1016/j.jaci.2017.01.027. Epub 2017 Feb 24.

18.

A Bioequivalence Test by the Direct Comparison of Concentration-versus-Time Curves Using Local Polynomial Smoothers.

Tian S, Chang HH, Orange D, Gu J, Suárez-Fariñas M.

Comput Math Methods Med. 2016;2016:4680642. doi: 10.1155/2016/4680642. Epub 2016 Dec 5.

19.

Alterations in B-cell subsets in pediatric patients with early atopic dermatitis.

Czarnowicki T, Esaki H, Gonzalez J, Renert-Yuval Y, Brunner P, Oliva M, Estrada Y, Xu H, Zheng X, Talasila S, Haugh I, Huynh T, Lyon S, Tran G, Sampson H, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E, Paller AS.

J Allergy Clin Immunol. 2017 Jul;140(1):134-144.e9. doi: 10.1016/j.jaci.2016.09.060. Epub 2016 Dec 10.

PMID:
27965110
20.

Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans.

Fuentes-Duculan J, Bonifacio KM, Suárez-Fariñas M, Kunjravia N, Garcet S, Cruz T, Wang CQF, Xu H, Gilleadeau P, Sullivan-Whalen M, Tirgan MH, Krueger JG.

Exp Dermatol. 2017 Aug;26(8):721-727. doi: 10.1111/exd.13271. Epub 2017 Feb 28.

21.

An Integrated Model of Atopic Dermatitis Biomarkers Highlights the Systemic Nature of the Disease.

Ungar B, Garcet S, Gonzalez J, Dhingra N, Correa da Rosa J, Shemer A, Krueger JG, Suarez-Farinas M, Guttman-Yassky E.

J Invest Dermatol. 2017 Mar;137(3):603-613. doi: 10.1016/j.jid.2016.09.037. Epub 2016 Nov 4.

22.

Digital imaging biomarkers feed machine learning for melanoma screening.

Gareau DS, Correa da Rosa J, Yagerman S, Carucci JA, Gulati N, Hueto F, DeFazio JL, Suárez-Fariñas M, Marghoob A, Krueger JG.

Exp Dermatol. 2017 Jul;26(7):615-618. doi: 10.1111/exd.13250. Epub 2016 Dec 19.

23.

The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes.

Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG.

J Invest Dermatol. 2016 Nov;136(11):2173-2182. doi: 10.1016/j.jid.2016.04.032. Epub 2016 May 13.

24.

Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway.

Bissonnette R, Fuentes-Duculan J, Mashiko S, Li X, Bonifacio KM, Cueto I, Suárez-Fariñas M, Maari C, Bolduc C, Nigen S, Sarfati M, Krueger JG.

J Dermatol Sci. 2017 Jan;85(1):20-26. doi: 10.1016/j.jdermsci.2016.09.019. Epub 2016 Sep 29.

PMID:
27743912
25.

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling.

Ewald DA, Noda S, Oliva M, Litman T, Nakajima S, Li X, Xu H, Workman CT, Scheipers P, Svitacheva N, Labuda T, Krueger JG, Suárez-Fariñas M, Kabashima K, Guttman-Yassky E.

J Allergy Clin Immunol. 2017 Feb;139(2):562-571. doi: 10.1016/j.jaci.2016.08.029. Epub 2016 Oct 1.

PMID:
27702671
26.

Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin.

Esaki H, Brunner PM, Renert-Yuval Y, Czarnowicki T, Huynh T, Tran G, Lyon S, Rodriguez G, Immaneni S, Johnson DB, Bauer B, Fuentes-Duculan J, Zheng X, Peng X, Estrada YD, Xu H, de Guzman Strong C, Suárez-Fariñas M, Krueger JG, Paller AS, Guttman-Yassky E.

J Allergy Clin Immunol. 2016 Dec;138(6):1639-1651. doi: 10.1016/j.jaci.2016.07.013. Epub 2016 Sep 23.

PMID:
27671162
27.

Shrinking the Psoriasis Assessment Gap: Early Gene-Expression Profiling Accurately Predicts Response to Long-Term Treatment.

Correa da Rosa J, Kim J, Tian S, Tomalin LE, Krueger JG, Suárez-Fariñas M.

J Invest Dermatol. 2017 Feb;137(2):305-312. doi: 10.1016/j.jid.2016.09.015. Epub 2016 Sep 22.

28.

An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis.

Paller AS, Renert-Yuval Y, Suprun M, Esaki H, Oliva M, Huynh TN, Ungar B, Kunjravia N, Friedland R, Peng X, Zheng X, Estrada YD, Krueger JG, Choate KA, Suárez-Fariñas M, Guttman-Yassky E.

J Allergy Clin Immunol. 2017 Jan;139(1):152-165. doi: 10.1016/j.jaci.2016.07.019. Epub 2016 Aug 20.

PMID:
27554821
29.

Patch testing of food allergens promotes Th17 and Th2 responses with increased IL-33: a pilot study.

Ungar B, Correa da Rosa J, Shemer A, Czarnowicki T, Estrada YD, Fuentes-Duculan J, Xu H, Zheng X, Peng X, Suárez-Fariñas M, Nowak-Wegrzyn A, Sampson HA, Krueger JG, Guttman-Yassky E.

Exp Dermatol. 2017 Mar;26(3):272-275. doi: 10.1111/exd.13148. Epub 2017 Jan 10. No abstract available.

PMID:
27488305
30.

Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria.

Mitsui H, Kiecker F, Shemer A, Cannizzaro MV, Wang CQF, Gulati N, Ohmatsu H, Shah KR, Gilleaudeau P, Sullivan-Whalen M, Cueto I, McNutt NS, Suárez-Fariñas M, Krueger JG.

J Invest Dermatol. 2016 Oct;136(10):2030-2040. doi: 10.1016/j.jid.2015.11.035. Epub 2016 Jul 1.

31.

Molecular Profiling of Immune Activation Associated with Regression of Melanoma Metastases Induced by Diphencyprone.

Gulati N, Garcet S, Fuentes-Duculan J, Gilleaudeau P, Sullivan-Whalen M, Li X, Suárez-Fariñas M, Coit DG, Krueger JG.

J Invest Dermatol. 2016 Oct;136(10):2101-2103. doi: 10.1016/j.jid.2016.06.611. Epub 2016 Jul 1. No abstract available.

32.

Correction: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris.

Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG.

PLoS One. 2016 Jun 21;11(6):e0158190. doi: 10.1371/journal.pone.0158190. eCollection 2016.

33.

Efficacy and safety of ustekinumab treatment in adults with moderate-to-severe atopic dermatitis.

Khattri S, Brunner PM, Garcet S, Finney R, Cohen SR, Oliva M, Dutt R, Fuentes-Duculan J, Zheng X, Li X, Bonifacio KM, Kunjravia N, Coats I, Cueto I, Gilleaudeau P, Sullivan-Whalen M, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E.

Exp Dermatol. 2017 Jan;26(1):28-35. doi: 10.1111/exd.13112. Epub 2016 Aug 9.

34.

Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris.

Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG.

PLoS One. 2016 May 6;11(5):e0155215. doi: 10.1371/journal.pone.0155215. eCollection 2016. Erratum in: PLoS One. 2016;11(6):e0158190.

35.

Tofacitinib attenuates pathologic immune pathways in patients with psoriasis: A randomized phase 2 study.

Krueger J, Clark JD, Suárez-Fariñas M, Fuentes-Duculan J, Cueto I, Wang CQ, Tan H, Wolk R, Rottinghaus ST, Whitley MZ, Valdez H, von Schack D, O'Neil SP, Reddy PS, Tatulych S; A3921147 Study Investigators.

J Allergy Clin Immunol. 2016 Apr;137(4):1079-1090. doi: 10.1016/j.jaci.2015.12.1318.

36.

Methotrexate improves pro- and anti-atherogenic genomic expression in psoriatic skin.

Goldminz AM, Suárez-Fariñas M, Wang AC, Dumont N, Krueger JG, Gottlieb AB.

J Dermatol Sci. 2016 Jun;82(3):207-9. doi: 10.1016/j.jdermsci.2016.03.007. Epub 2016 Mar 9. No abstract available.

PMID:
27005302
37.

A mild topical steroid leads to progressive anti-inflammatory effects in the skin of patients with moderate-to-severe atopic dermatitis.

Brunner PM, Khattri S, Garcet S, Finney R, Oliva M, Dutt R, Fuentes-Duculan J, Zheng X, Li X, Bonifacio KM, Kunjravia N, Coats I, Cueto I, Gilleaudeau P, Sullivan-Whalen M, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E.

J Allergy Clin Immunol. 2016 Jul;138(1):169-78. doi: 10.1016/j.jaci.2015.12.1323. Epub 2016 Mar 2.

PMID:
26948076
38.

Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis.

Ruano J, Suárez-Fariñas M, Shemer A, Oliva M, Guttman-Yassky E, Krueger JG.

PLoS One. 2016 Feb 5;11(2):e0148450. doi: 10.1371/journal.pone.0148450. eCollection 2016.

39.

Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets.

Kim J, Oh CH, Jeon J, Baek Y, Ahn J, Kim DJ, Lee HS, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG.

J Invest Dermatol. 2016 Jan;136(1):161-72. doi: 10.1038/JID.2015.378.

40.

The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases.

Harden JL, Lewis SM, Lish SR, Suárez-Fariñas M, Gareau D, Lentini T, Johnson-Huang LM, Krueger JG, Lowes MA.

J Allergy Clin Immunol. 2016 Jun;137(6):1830-1840. doi: 10.1016/j.jaci.2015.09.055. Epub 2015 Dec 22.

41.

Biomarkers of alopecia areata disease activity and response to corticosteroid treatment.

Fuentes-Duculan J, Gulati N, Bonifacio KM, Kunjravia N, Zheng X, Suárez-Fariñas M, Shemer A, Guttman-Yassky E, Krueger JG.

Exp Dermatol. 2016 Apr;25(4):282-6. doi: 10.1111/exd.12918. Epub 2016 Mar 3.

PMID:
26661294
42.

Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism.

Guttman-Yassky E, Ungar B, Noda S, Suprun M, Shroff A, Dutt R, Khattri S, Min M, Mansouri Y, Zheng X, Estrada YD, Singer GK, Suarez-Farinas M, Krueger JG, Lebwohl MG.

J Allergy Clin Immunol. 2016 Jan;137(1):301-304. doi: 10.1016/j.jaci.2015.11.001. Epub 2015 Nov 20. No abstract available.

PMID:
26607705
43.

A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis.

Krueger JG, Suárez-Fariñas M, Cueto I, Khacherian A, Matheson R, Parish LC, Leonardi C, Shortino D, Gupta A, Haddad J, Vlasuk GP, Jacobson EW.

PLoS One. 2015 Nov 10;10(11):e0142081. doi: 10.1371/journal.pone.0142081. eCollection 2015.

44.

Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways.

Ewald DA, Malajian D, Krueger JG, Workman CT, Wang T, Tian S, Litman T, Guttman-Yassky E, Suárez-Fariñas M.

BMC Med Genomics. 2015 Oct 12;8:60. doi: 10.1186/s12920-015-0133-x.

45.

Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer.

Czarnowicki T, Malajian D, Khattri S, Correa da Rosa J, Dutt R, Finney R, Dhingra N, Xiangyu P, Xu H, Estrada YD, Zheng X, Gilleaudeau P, Sullivan-Whalen M, Suaréz-Fariñas M, Shemer A, Krueger JG, Guttman-Yassky E.

J Allergy Clin Immunol. 2016 Apr;137(4):1091-1102.e7. doi: 10.1016/j.jaci.2015.08.013. Epub 2015 Oct 1.

PMID:
26431582
46.

The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.

Noda S, Suárez-Fariñas M, Ungar B, Kim SJ, de Guzman Strong C, Xu H, Peng X, Estrada YD, Nakajima S, Honda T, Shin JU, Lee H, Krueger JG, Lee KH, Kabashima K, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Nov;136(5):1254-64. doi: 10.1016/j.jaci.2015.08.015. Epub 2015 Oct 1.

PMID:
26428954
47.

Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.

Suárez-Fariñas M, Ungar B, Noda S, Shroff A, Mansouri Y, Fuentes-Duculan J, Czernik A, Zheng X, Estrada YD, Xu H, Peng X, Shemer A, Krueger JG, Lebwohl MG, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Nov;136(5):1277-87. doi: 10.1016/j.jaci.2015.06.032. Epub 2015 Aug 24.

PMID:
26316095
48.

Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.

Goldstein J, Roth E, Roberts N, Zwick R, Lin S, Fletcher S, Tadeu A, Wu C, Beck A, Zeiss C, Suárez-Fariñas M, Horsley V.

Mol Biol Cell. 2015 Oct 15;26(20):3606-14. doi: 10.1091/mbc.E15-05-0282. Epub 2015 Aug 26.

49.

Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)(+) TH2/TH1 cell imbalance, whereas adults acquire CLA(+) TH22/TC22 cell subsets.

Czarnowicki T, Esaki H, Gonzalez J, Malajian D, Shemer A, Noda S, Talasila S, Berry A, Gray J, Becker L, Estrada Y, Xu H, Zheng X, Suárez-Fariñas M, Krueger JG, Paller AS, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Oct;136(4):941-951.e3. doi: 10.1016/j.jaci.2015.05.049. Epub 2015 Aug 1.

50.

Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions.

Gulati N, Suárez-Fariñas M, Correa da Rosa J, Krueger JG.

F1000Res. 2015 Jun 11;4:149. doi: 10.12688/f1000research.6581.1. eCollection 2015.

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