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Items: 1 to 50 of 98


Isorhynchophylline exerts antidepressant-like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3β signaling pathway.

Xian YF, Ip SP, Li HQ, Qu C, Su ZR, Chen JN, Lin ZX.

FASEB J. 2019 Jun 24:fj201802743RR. doi: 10.1096/fj.201802743RR. [Epub ahead of print]


Therapeutic effect of Brucea javanica oil emulsion on experimental Crohn's disease in rats: Involvement of TLR4/ NF-κB signaling pathway.

Huang YF, Li QP, Dou YX, Wang TT, Qu C, Liang JL, Lin ZX, Huang XQ, Su ZR, Chen JN, Xie YL.

Biomed Pharmacother. 2019 Jun;114:108766. doi: 10.1016/j.biopha.2019.108766. Epub 2019 Mar 20.


Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis.

Zhang X, Wu JZ, Lin ZX, Yuan QJ, Li YC, Liang JL, Zhan JY, Xie YL, Su ZR, Liu YH.

J Ethnopharmacol. 2019 Apr 24;234:44-56. doi: 10.1016/j.jep.2018.12.050. Epub 2019 Jan 2.


Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo.

Li CL, Tan LH, Wang YF, Luo CD, Chen HB, Lu Q, Li YC, Yang XB, Chen JN, Liu YH, Xie JH, Su ZR.

Phytomedicine. 2019 Jan;52:272-283. doi: 10.1016/j.phymed.2018.09.228. Epub 2018 Oct 1.


Palmatine attenuated dextran sulfate sodium (DSS)-induced colitis via promoting mitophagy-mediated NLRP3 inflammasome inactivation.

Mai CT, Wu MM, Wang CL, Su ZR, Cheng YY, Zhang XJ.

Mol Immunol. 2019 Jan;105:76-85. doi: 10.1016/j.molimm.2018.10.015. Epub 2018 Nov 27.


Comparison of the anti-inflammatory effects of Sinapis alba and Brassica juncea in mouse models of inflammation.

Xian YF, Hu Z, Ip SP, Chen JN, Su ZR, Lai XP, Lin ZX.

Phytomedicine. 2018 Nov 15;50:196-204. doi: 10.1016/j.phymed.2018.05.010. Epub 2018 May 19.


Tetrahydrocurcumin and octahydrocurcumin, the primary and final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: Role of CYP2E1 and Keap1-Nrf2 pathway.

Luo DD, Chen JF, Liu JJ, Xie JH, Zhang ZB, Gu JY, Zhuo JY, Huang S, Su ZR, Sun ZH.

Food Chem Toxicol. 2019 Jan;123:349-362. doi: 10.1016/j.fct.2018.11.012. Epub 2018 Nov 10.


Curcumin's Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects in vivo Through Suppression of TAK1-NF-κB Pathway.

Zhang ZB, Luo DD, Xie JH, Xian YF, Lai ZQ, Liu YH, Liu WH, Chen JN, Lai XP, Lin ZX, Su ZR.

Front Pharmacol. 2018 Oct 17;9:1181. doi: 10.3389/fphar.2018.01181. eCollection 2018.


Polydatin protects against acetaminophen-induced hepatotoxicity in mice via anti-oxidative and anti-apoptotic activities.

Liu YH, Huang QH, Wu X, Wu JZ, Liang JL, Lin GS, Xu LQ, Lai XP, Su ZR, Chen JN.

Food Funct. 2018 Nov 14;9(11):5891-5902. doi: 10.1039/c8fo01078a.


Self-nanoemulsifying drug delivery system of bruceine D: a new approach for anti-ulcerative colitis.

Dou YX, Zhou JT, Wang TT, Huang YF, Chen VP, Xie YL, Lin ZX, Gao JS, Su ZR, Zeng HF.

Int J Nanomedicine. 2018 Sep 28;13:5887-5907. doi: 10.2147/IJN.S174146. eCollection 2018.


Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota.

Zhang XJ, Yuan ZW, Qu C, Yu XT, Huang T, Chen PV, Su ZR, Dou YX, Wu JZ, Zeng HF, Xie Y, Chen JN.

Pharmacol Res. 2018 Nov;137:34-46. doi: 10.1016/j.phrs.2018.09.010. Epub 2018 Sep 19.


Angelica sinensis Supercritical Fluid CO2 Extract Attenuates D-Galactose-Induced Liver and Kidney Impairment in Mice by Suppressing Oxidative Stress and Inflammation.

Mo ZZ, Lin ZX, Su ZR, Zheng L, Li HL, Xie JH, Xian YF, Yi TG, Huang SQ, Chen JP.

J Med Food. 2018 Sep;21(9):887-898. doi: 10.1089/jmf.2017.4061. Epub 2018 Aug 15.


Pogostone attenuates TNF-α-induced injury in A549 cells via inhibiting NF-κB and activating Nrf2 pathways.

Yang HM, Zhuo JY, Sun CY, Nie J, Yuan J, Liu YL, Lin RF, Lai XP, Su ZR, Li YC.

Int Immunopharmacol. 2018 Sep;62:15-22. doi: 10.1016/j.intimp.2018.06.029. Epub 2018 Jun 30.


Scutellarin Enhances Antitumor Effects and Attenuates the Toxicity of Bleomycin in H22 Ascites Tumor-Bearing Mice.

Nie J, Yang HM, Sun CY, Liu YL, Zhuo JY, Zhang ZB, Lai XP, Su ZR, Li YC.

Front Pharmacol. 2018 Jun 14;9:615. doi: 10.3389/fphar.2018.00615. eCollection 2018.


Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice.

Yu XT, Xu YF, Huang YF, Qu C, Xu LQ, Su ZR, Zeng HF, Zheng L, Yi TG, Li HL, Chen JP, Zhang XJ.

PLoS One. 2018 Mar 14;13(3):e0194069. doi: 10.1371/journal.pone.0194069. eCollection 2018.


Protective role of β-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer in rats: Involvement of anti-inflammation and angiogenesis.

Wu JZ, Liu YH, Liang JL, Huang QH, Dou YX, Nie J, Zhuo JY, Wu X, Chen JN, Su ZR, Wu QD.

Phytomedicine. 2018 Jan 15;39:111-118. doi: 10.1016/j.phymed.2017.12.024. Epub 2017 Dec 25.


Synergistic antitumor effect of brusatol combined with cisplatin on colorectal cancer cells.

Chen HM, Lai ZQ, Liao HJ, Xie JH, Xian YF, Chen YL, Ip SP, Lin ZX, Su ZR.

Int J Mol Med. 2018 Mar;41(3):1447-1454. doi: 10.3892/ijmm.2018.3372. Epub 2018 Jan 9.


Brucein D, a Naturally Occurring Tetracyclic Triterpene Quassinoid, Induces Apoptosis in Pancreatic Cancer through ROS-Associated PI3K/Akt Signaling Pathway.

Lai ZQ, Ip SP, Liao HJ, Lu Z, Xie JH, Su ZR, Chen YL, Xian YF, Leung PS, Lin ZX.

Front Pharmacol. 2017 Dec 22;8:936. doi: 10.3389/fphar.2017.00936. eCollection 2017.


Polydatin Protects Rat Liver against Ethanol-Induced Injury: Involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-κB p65 Pathway.

Huang QH, Xu LQ, Liu YH, Wu JZ, Wu X, Lai XP, Li YC, Su ZR, Chen JN, Xie YL.

Evid Based Complement Alternat Med. 2017;2017:7953850. doi: 10.1155/2017/7953850. Epub 2017 Nov 8.


Protective effects of silymarin on triptolide-induced acute hepatotoxicity in rats.

Wang L, Huang QH, Li YX, Huang YF, Xie JH, Xu LQ, Dou YX, Su ZR, Zeng HF, Chen JN.

Mol Med Rep. 2018 Jan;17(1):789-800. doi: 10.3892/mmr.2017.7958. Epub 2017 Nov 3.


Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS.

Liang JL, Wu JZ, Liu YH, Zhang ZB, Wu QD, Chen HB, Huang YF, Dou YX, Zhou JT, Su ZR, Zhan JY.

Mediators Inflamm. 2017;2017:1089028. doi: 10.1155/2017/1089028. Epub 2017 Jul 25.


β-Patchoulene from patchouli oil protects against LPS-induced acute lung injury via suppressing NF-κB and activating Nrf2 pathways.

Chen XY, Dou YX, Luo DD, Zhang ZB, Li CL, Zeng HF, Su ZR, Xie JH, Lai XP, Li YC.

Int Immunopharmacol. 2017 Sep;50:270-278. doi: 10.1016/j.intimp.2017.07.001. Epub 2017 Jul 13.


Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.

Chen HB, Luo CD, Liang JL, Zhang ZB, Lin GS, Wu JZ, Li CL, Tan LH, Yang XB, Su ZR, Xie JH, Zeng HF.

Eur J Pharmacol. 2017 Sep 15;811:222-231. doi: 10.1016/j.ejphar.2017.06.027. Epub 2017 Jun 23.


Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism.

Qu C, Yuan ZW, Yu XT, Huang YF, Yang GH, Chen JN, Lai XP, Su ZR, Zeng HF, Xie Y, Zhang XJ.

Pharmacol Res. 2017 Jul;121:70-82. doi: 10.1016/j.phrs.2017.04.017. Epub 2017 Apr 27.


Different effects of (+)‑borneol and (‑)‑borneol on the pharmacokinetics of osthole in rats following oral administration.

Luo DD, Chen XY, Zhang ZB, Sun CY, Zheng YF, Liu YH, Wang XF, Wang Q, Zhan JY, Su ZR.

Mol Med Rep. 2017 Jun;15(6):4239-4246. doi: 10.3892/mmr.2017.6502. Epub 2017 Apr 21.


The immune-regulating effect of Xiao'er Qixingcha in constipated mice induced by high-heat and high-protein diet.

Qu C, Yang GH, Zheng RB, Yu XT, Peng SZ, Xie JH, Chen JN, Wang XF, Su ZR, Zhang XJ.

BMC Complement Altern Med. 2017 Mar 31;17(1):185. doi: 10.1186/s12906-017-1700-9.


In Vitro and In Vivo Antibacterial Activities of Patchouli Alcohol, a Naturally Occurring Tricyclic Sesquiterpene, against Helicobacter pylori Infection.

Xu YF, Lian DW, Chen YQ, Cai YF, Zheng YF, Fan PL, Ren WK, Fu LJ, Li YC, Xie JH, Cao HY, Tan B, Su ZR, Huang P.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00122-17. doi: 10.1128/AAC.00122-17. Print 2017 Jun.


Effect-enhancing and toxicity-reducing activity of usnic acid in ascitic tumor-bearing mice treated with bleomycin.

Su ZQ, Liu YH, Guo HZ, Sun CY, Xie JH, Li YC, Chen JN, Lai XP, Su ZR, Chen HM.

Int Immunopharmacol. 2017 May;46:146-155. doi: 10.1016/j.intimp.2017.03.004. Epub 2017 Mar 8.


Anti-inflammatory effects of Brucea javanica oil emulsion by suppressing NF-κB activation on dextran sulfate sodium-induced ulcerative colitis in mice.

Huang YF, Zhou JT, Qu C, Dou YX, Huang QH, Lin ZX, Xian YF, Xie JH, Xie YL, Lai XP, Su ZR.

J Ethnopharmacol. 2017 Feb 23;198:389-398. doi: 10.1016/j.jep.2017.01.042. Epub 2017 Jan 22.


Protective Effect of SFE-CO2 of Ligusticum chuanxiong Hort Against d-Galactose-Induced Injury in the Mouse Liver and Kidney.

Mo ZZ, Liu YH, Li CL, Xu LQ, Wen LL, Xian YF, Lin ZX, Zhan JY, Chen JN, Xu FF, Su ZR.

Rejuvenation Res. 2017 Jun;20(3):231-243. doi: 10.1089/rej.2016.1870. Epub 2017 Feb 23.


Inhibition of Helicobacter pylori and Its Associated Urease by Palmatine: Investigation on the Potential Mechanism.

Zhou JT, Li CL, Tan LH, Xu YF, Liu YH, Mo ZZ, Dou YX, Su R, Su ZR, Huang P, Xie JH.

PLoS One. 2017 Jan 3;12(1):e0168944. doi: 10.1371/journal.pone.0168944. eCollection 2017.


Aqueous Extract of Clerodendranthus spicatus Exerts Protective Effect on UV-Induced Photoaged Mice Skin.

Wang L, Zhang X, Li YX, Xu LQ, Li CL, Zhang ZB, Liang JL, Su ZR, Zeng HF, Li YC.

Evid Based Complement Alternat Med. 2016;2016:9623957. Epub 2016 Oct 25.


Polydatin attenuates d-galactose-induced liver and brain damage through its anti-oxidative, anti-inflammatory and anti-apoptotic effects in mice.

Xu LQ, Xie YL, Gui SH, Zhang X, Mo ZZ, Sun CY, Li CL, Luo DD, Zhang ZB, Su ZR, Xie JH.

Food Funct. 2016 Nov 9;7(11):4545-4555.


miR-106b promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma.

Yen CS, Su ZR, Lee YP, Liu IT, Yen CJ.

World J Gastroenterol. 2016 Jun 14;22(22):5183-92. doi: 10.3748/wjg.v22.i22.5183.


Medicinal herbs Fructus corni and Semen cuscutae suppress allograft rejection via distinct immune mechanisms.

Liu X, Zeng YQ, Liang YZ, Zou C, Liu H, Qiu F, Liang CL, Jin XW, Su ZR, Dai Z.

Oncotarget. 2016 Jun 14;7(24):35680-35691. doi: 10.18632/oncotarget.9680.


Synthesis of pogostone by one-step.

Chen HB, Zhou JT, Liu YH, Zhang ZB, Zhan YX, Su ZR, Zeng HF.

J Asian Nat Prod Res. 2017 Feb;19(2):172-175. doi: 10.1080/10286020.2016.1184253. Epub 2016 May 31.


Kegan Liyan oral liquid ameliorates lipopolysaccharide-induced acute lung injury through inhibition of TLR4-mediated NF-κB signaling pathway and MMP-9 expression.

Zhang X, Sun CY, Zhang YB, Guo HZ, Feng XX, Peng SZ, Yuan J, Zheng RB, Chen WP, Su ZR, Huang XD.

J Ethnopharmacol. 2016 Jun 20;186:91-102. doi: 10.1016/j.jep.2016.03.057. Epub 2016 Mar 30.


Photo-protective activity of pogostone against UV-induced skin premature aging in mice.

Wang XF, Huang YF, Wang L, Xu LQ, Yu XT, Liu YH, Li CL, Zhan JY, Su ZR, Chen JN, Zeng HF.

Exp Gerontol. 2016 May;77:76-86. doi: 10.1016/j.exger.2016.02.017. Epub 2016 Feb 27. Review.


Protective effects of pogostone against LPS-induced acute lung injury in mice via regulation of Keap1-Nrf2/NF-κB signaling pathways.

Sun CY, Xu LQ, Zhang ZB, Chen CH, Huang YZ, Su ZQ, Guo HZ, Chen XY, Zhang X, Liu YH, Chen JN, Lai XP, Li YC, Su ZR.

Int Immunopharmacol. 2016 Mar;32:55-61. doi: 10.1016/j.intimp.2016.01.007. Epub 2016 Jan 19.


Evaluation of safety of modified-Danggui Buxue Tang in rodents:immunological, toxicity and hormonal aspects.

Xie JH, Chen ZW, Pan YW, Luo DM, Su ZR, Chen HM, Qin Z, Huang SQ, Lei G.

J Ethnopharmacol. 2016 May 13;183:59-70. doi: 10.1016/j.jep.2015.12.049. Epub 2015 Dec 28.


Anti-Fatigue and Antioxidant Activity of the Polysaccharides Isolated from Millettiae speciosae Champ. Leguminosae.

Zhao XN, Liang JL, Chen HB, Liang YE, Guo HZ, Su ZR, Li YC, Zeng HF, Zhang XJ.

Nutrients. 2015 Oct 21;7(10):8657-69. doi: 10.3390/nu7105422.


The gastroprotective effect of pogostone from Pogostemonis Herba against indomethacin-induced gastric ulcer in rats.

Chen XY, Chen HM, Liu YH, Zhang ZB, Zheng YF, Su ZQ, Zhang X, Xie JH, Liang YZ, Fu LD, Lai XP, Su ZR, Huang XQ.

Exp Biol Med (Maywood). 2016 Jan;241(2):193-204. doi: 10.1177/1535370215600099. Epub 2015 Aug 19.


Andrographolide sodium bisulphite-induced inactivation of urease: inhibitory potency, kinetics and mechanism.

Mo ZZ, Wang XF, Zhang X, Su JY, Chen HM, Liu YH, Zhang ZB, Xie JH, Su ZR.

BMC Complement Altern Med. 2015 Jul 16;15:238. doi: 10.1186/s12906-015-0775-4.


Discovery of xanthine oxidase inhibitors and/or α-glucosidase inhibitors by carboxyalkyl derivatization based on the flavonoid of apigenin.

Su ZR, Fan SY, Shi WG, Zhong BH.

Bioorg Med Chem Lett. 2015 Jul 15;25(14):2778-81. doi: 10.1016/j.bmcl.2015.05.016. Epub 2015 May 14.


Gastroprotective effect of andrographolide sodium bisulfite against indomethacin-induced gastric ulceration in rats.

Liu YH, Zhang ZB, Zheng YF, Chen HM, Yu XT, Chen XY, Zhang X, Xie JH, Su ZQ, Feng XX, Zeng HF, Su ZR.

Int Immunopharmacol. 2015 Jun;26(2):384-91. doi: 10.1016/j.intimp.2015.04.025. Epub 2015 Apr 24.


Honokiol improves learning and memory impairments induced by scopolamine in mice.

Xian YF, Ip SP, Mao QQ, Su ZR, Chen JN, Lai XP, Lin ZX.

Eur J Pharmacol. 2015 Aug 5;760:88-95. doi: 10.1016/j.ejphar.2015.04.013. Epub 2015 Apr 23.


Immunosuppressive activity of pogostone on T cells: Blocking proliferation via S phase arrest.

Su JY, Luo X, Zhang XJ, Deng XL, Su ZR, Zhou L, Li SS, Dai Z, Xu Y, Lai XP.

Int Immunopharmacol. 2015 Jun;26(2):328-37. doi: 10.1016/j.intimp.2015.04.019. Epub 2015 Apr 21.


A Standardized Traditional Chinese Medicine Preparation Named Yejuhua Capsule Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Downregulating Toll-Like Receptor 4/Nuclear Factor-κB.

Li CW, Chen ZW, Wu XL, Ning ZX, Su ZQ, Li YC, Su ZR, Lai XP.

Evid Based Complement Alternat Med. 2015;2015:264612. doi: 10.1155/2015/264612. Epub 2015 Mar 23.


Protective Effect of Super-Critical Carbon Dioxide Fluid Extract from Flowers and Buds of Chrysanthemum indicum Linnén Against Ultraviolet-Induced Photo-Aging in Mice.

Zhang X, Xie YL, Yu XT, Su ZQ, Yuan J, Li YC, Su ZR, Zhan JY, Lai XP.

Rejuvenation Res. 2015 Oct;18(5):437-48. doi: 10.1089/rej.2014.1651. Epub 2015 Aug 20.


Novel patchouli alcohol ternary solid dispersion pellets prepared by poloxamers.

Liao JB, Liang YZ, Chen YL, Xie JH, Liu WH, Chen JN, Lai XP, Su ZR.

Iran J Pharm Res. 2015 Winter;14(1):15-26.

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