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Identifying Novel Genetic Markers Through Transcription-Wide Association Study: Can This Be A Path To Reducing The Burden of Pancreatic cancer?

Genkinger JM, Su GH, Santella RM.

J Natl Cancer Inst. 2020 Jan 9. pii: djz247. doi: 10.1093/jnci/djz247. [Epub ahead of print] No abstract available.


MicroRNA-150 alleviates acute myocardial infarction through regulating cardiac fibroblasts in ventricular remodeling.

Tian HB, Li SH, Hu KQ, Zan YS, Zhang XL, Su GH.

Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7611-7618. doi: 10.26355/eurrev_201909_18884.


Validation of a nomogram to predict the risk of cancer in patients with intraductal papillary mucinous neoplasm and main duct dilatation of 10 mm or less.

Jung W, Park T, Kim Y, Park H, Han Y, He J, Wolfgang CL, Blair A, Rashid MF, Kluger MD, Su GH, Chabot JA, Yang CY, Lou W, Valente R, Del Chiaro M, Shyr YM, Wang SE, van Huijgevoort NCM, Besselink MG, Yang Y, Kim H, Kwon W, Kim SW, Jang JY.

Br J Surg. 2019 Dec;106(13):1829-1836. doi: 10.1002/bjs.11293. Epub 2019 Aug 23.


[Effects of Clinical Characteristics, Laboratory Parameters and Treatment Regimens on Prognosis of Patients with Multiple Myeloma].

Xu L, Chen ZL, Hu M, Tao S, Chen Y, Su GH.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Aug;27(4):1166-1172. doi: 10.19746/j.cnki.issn.1009-2137.2019.04.028. Chinese.


Abemaciclib Is Effective Against Pancreatic Cancer Cells and Synergizes with HuR and YAP1 Inhibition.

Dhir T, Schultz CW, Jain A, Brown SZ, Haber A, Goetz A, Xi C, Su GH, Xu L, Posey J 3rd, Jiang W, Yeo CJ, Golan T, Pishvaian MJ, Brody JR.

Mol Cancer Res. 2019 Oct;17(10):2029-2041. doi: 10.1158/1541-7786.MCR-19-0589. Epub 2019 Aug 5.


Ivabradine Improves Cardiac Function and Increases Exercise Capacity in Patients with Chronic Heart Failure.

Pei H, Miao W, Xie WZ, Wang W, Zhao D, Su GH, Zhao Z.

Int Heart J. 2019 Jul 27;60(4):899-909. doi: 10.1536/ihj.18-559. Epub 2019 Jul 12.


Dasatinib can enhance paclitaxel and gemcitabine inhibitory activity in human pancreatic cancer cells.

Ma L, Wei J, Su GH, Lin J.

Cancer Biol Ther. 2019;20(6):855-865. doi: 10.1080/15384047.2019.1579956. Epub 2019 Mar 13.


Lowering hepatic venous pressure agent carvedilol versus variceal banding ligation for clinical outcomes of cirrhotic portal hypertension.

Wei ZG, Wei FX, Shao ZW, Su GH, Qi XP, Zhang YC.

Ther Clin Risk Manag. 2018 Dec 24;15:45-57. doi: 10.2147/TCRM.S184863. eCollection 2019. Review.


HHLA2 is a novel immune checkpoint protein in pancreatic ductal adenocarcinoma and predicts post-surgical survival.

Yan H, Qiu W, Koehne de Gonzalez AK, Wei JS, Tu M, Xi CH, Yang YR, Peng YP, Tsai WY, Remotti HE, Miao Y, Su GH.

Cancer Lett. 2019 Feb 1;442:333-340. doi: 10.1016/j.canlet.2018.11.007. Epub 2018 Nov 14.


Isolation of Extracellular Vesicles for Cancer Diagnosis and Functional Studies.

Brenner AW, Su GH, Momen-Heravi F.

Methods Mol Biol. 2019;1882:229-237. doi: 10.1007/978-1-4939-8879-2_21.


Nano-particle engineered atorvastatin delivery to support mesenchymal stem cell survival in infarcted myocardium.

Yao GT, Song LP, Xue WH, Su GH, Ning AH, Wang J.

Saudi J Biol Sci. 2018 Sep;25(6):1016-1021. doi: 10.1016/j.sjbs.2017.03.015. Epub 2017 Apr 4.


Blocking IL-6/GP130 Signaling Inhibits Cell Viability/Proliferation, Glycolysis, and Colony Forming Activity in Human Pancreatic Cancer Cells.

Chen X, Tian J, Su GH, Lin J.

Curr Cancer Drug Targets. 2019;19(5):417-427. doi: 10.2174/1568009618666180430123939.


The use of a novel non-steroidal mineralocorticoid receptor antagonist finerenone for the treatment of chronic heart failure: A systematic review and meta-analysis.

Pei H, Wang W, Zhao D, Wang L, Su GH, Zhao Z.

Medicine (Baltimore). 2018 Apr;97(16):e0254. doi: 10.1097/MD.0000000000010254.


Pancreatic DCLK1+ cells originate distinctly from PDX1+ progenitors and contribute to the initiation of intraductal papillary mucinous neoplasm in mice.

Qiu W, Remotti HE, Tang SM, Wang E, Dobberteen L, Lee Youssof A, Lee JH, Cheung EC, Su GH.

Cancer Lett. 2018 Jun 1;423:71-79. doi: 10.1016/j.canlet.2018.03.009. Epub 2018 Mar 8.


Whole genome sequencing of pairwise human subjects reveals DNA mutations specific to developmental dysplasia of the hip.

Zhu LQ, Su GH, Dai J, Zhang WY, Yin CH, Zhang FY, Zhu ZH, Guo ZX, Fang JF, Zou CD, Chen XG, Zhang Y, Xu CY, Zhen YF, Wang XD.

Genomics. 2019 May;111(3):320-326. doi: 10.1016/j.ygeno.2018.02.006. Epub 2018 Feb 25.


Activin receptors regulate the oligodendrocyte lineage in health and disease.

Dillenburg A, Ireland G, Holloway RK, Davies CL, Evans FL, Swire M, Bechler ME, Soong D, Yuen TJ, Su GH, Becher JC, Smith C, Williams A, Miron VE.

Acta Neuropathol. 2018 Jun;135(6):887-906. doi: 10.1007/s00401-018-1813-3. Epub 2018 Feb 3.


NIR responsive liposomal system for rapid release of drugs in cancer therapy.

Chen MM, Liu YY, Su GH, Song FF, Liu Y, Zhang QQ.

Int J Nanomedicine. 2017 Jun 6;12:4225-4239. doi: 10.2147/IJN.S130861. eCollection 2017.


Insights into the function of n-3 PUFAs in fat-1 transgenic cattle.

Liu XF, Wei ZY, Bai CL, Ding XB, Li X, Su GH, Cheng L, Zhang L, Guo H, Li GP.

J Lipid Res. 2017 Aug;58(8):1524-1535. doi: 10.1194/jlr.M072983. Epub 2017 Jun 16.


ACSS2 gene variant associated with cleft lip and palate in two independent Hispanic populations.

Dodhia S, Celis K, Aylward A, Cai Y, Fontana ME, Trespalacios A, Hoffman DC, Alfonso HO, Eisig SB, Su GH, Chung WK, Haddad J Jr.

Laryngoscope. 2017 Oct;127(10):E336-E339. doi: 10.1002/lary.26637. Epub 2017 May 23.


Nasopharyngeal papillomas treated with CO2 laser and human papillomavirus vaccination.

Cai Y, Merea VS, Lee AH, Su GH, Caruana SM.

Laryngoscope. 2017 Oct;127(10):2279-2281. doi: 10.1002/lary.26580. Epub 2017 Apr 13.


Aspirin alleviates cardiac fibrosis in mice by inhibiting autophagy.

Liu PP, Liu HH, Sun SH, Shi XX, Yang WC, Su GH, Zhao J.

Acta Pharmacol Sin. 2017 Apr;38(4):488-497. doi: 10.1038/aps.2016.143. Epub 2017 Feb 20.


Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma.

Cai Y, Dodhia S, Su GH.

Oncotarget. 2017 Mar 28;8(13):22203-22217. doi: 10.18632/oncotarget.14729. Review.


Patchouli alcohol attenuates experimental atherosclerosis via inhibiting macrophage infiltration and its inflammatory responses.

Wang HT, Wang ZZ, Wang ZC, Wang SM, Cai XJ, Su GH, Yuan ZY.

Biomed Pharmacother. 2016 Oct;83:930-935. doi: 10.1016/j.biopha.2016.08.005. Epub 2016 Aug 11.


Mutant allele specific imbalance in oncogenes with copy number alterations: Occurrence, mechanisms, and potential clinical implications.

Yu CC, Qiu W, Juang CS, Mansukhani MM, Halmos B, Su GH.

Cancer Lett. 2017 Jan 1;384:86-93. doi: 10.1016/j.canlet.2016.10.013. Epub 2016 Oct 8. Review.


[Randomized controlled trials of needle knife therapy combined with rotation traction manipulation for the treatment of cervical spondylotic radiculopathy].

Zhou ZL, Su GH, Zheng BZ, Zuo YZ, Wei FL.

Zhongguo Gu Shang. 2016 Sep 25;29(9):820-824. doi: 10.3969/j.issn.1003-0034.2016.09.010. Chinese.


Efficacy and safety of proprotein convertase subtilisin/kexin type 9 monoclonal antibody in adults with familial hypercholesterolemia.

Li B, Hao PP, Zhang Y, Yin RH, Kong QZ, Cai XJ, Zhao Z, Qi JN, Li Y, Xiao J, Wang F, Yi W, Ji XP, Su GH.

Oncotarget. 2017 May 2;8(18):30455-30463. doi: 10.18632/oncotarget.10762.


Inhibitory effect of Gardenblue blueberry (Vaccinium ashei Reade) anthocyanin extracts on lipopolysaccharide-stimulated inflammatory response in RAW 264.7 cells.

Xu W, Zhou Q, Yao Y, Li X, Zhang JL, Su GH, Deng AP.

J Zhejiang Univ Sci B. 2016 Jun;17(6):425-36. doi: 10.1631/jzus.B1500213.


Relaxin-2 improves diastolic function of pressure-overloaded rats via phospholamban by activating Akt.

Shuai XX, Meng YD, Lu YX, Su GH, Tao XF, Han J, Xu SD, Luo P.

Int J Cardiol. 2016 Sep 1;218:305-311. doi: 10.1016/j.ijcard.2016.05.011. Epub 2016 May 17.


Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas.

García-Carracedo D, Villaronga MÁ, Álvarez-Teijeiro S, Hermida-Prado F, Santamaría I, Allonca E, Suárez-Fernández L, Gonzalez MV, Balbín M, Astudillo A, Martínez-Camblor P, Su GH, Rodrigo JP, García-Pedrero JM.

Oncotarget. 2016 May 17;7(20):29780-93. doi: 10.18632/oncotarget.8957.


Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis.

Westphalen CB, Takemoto Y, Tanaka T, Macchini M, Jiang Z, Renz BW, Chen X, Ormanns S, Nagar K, Tailor Y, May R, Cho Y, Asfaha S, Worthley DL, Hayakawa Y, Urbanska AM, Quante M, Reichert M, Broyde J, Subramaniam PS, Remotti H, Su GH, Rustgi AK, Friedman RA, Honig B, Califano A, Houchen CW, Olive KP, Wang TC.

Cell Stem Cell. 2016 Apr 7;18(4):441-55. doi: 10.1016/j.stem.2016.03.016.


p21-activated kinase 1 (PAK1) expression correlates with prognosis in solid tumors: A systematic review and meta-analysis.

Fang F, Pan J, Li YP, Li G, Xu LX, Su GH, Li ZH, Feng X, Wang J.

Oncotarget. 2016 May 10;7(19):27422-9. doi: 10.18632/oncotarget.8320. Review.


Cyclic GMP-AMP Synthase Is Required for Cell Proliferation and Inflammatory Responses in Rheumatoid Arthritis Synoviocytes.

Wang Y, Su GH, Zhang F, Chu JX, Wang YS.

Mediators Inflamm. 2015;2015:192329. doi: 10.1155/2015/192329. Epub 2015 Dec 27.


Association between alcohol dehydrogenase 1C gene *1/*2 polymorphism and pancreatitis risk: a meta-analysis.

Fang F, Pan J, Su GH, Xu LX, Li G, Li ZH, Zhao H, Wang J.

Genet Mol Res. 2015 Nov 30;14(4):15267-75. doi: 10.4238/2015.November.30.2.


Analysis of soluble urokinase plasminogen activator receptor in multiple myeloma for predicting prognosis.

Shen J, Wang Q, Wang J, Su GH, Wang J, Guo SH, Liu YA, Wu Z, Liu RF, Li X, Guo XJ, Cao J, Zhang YH, Wang ZY.

Oncol Lett. 2015 Oct;10(4):2403-2409. Epub 2015 Aug 14.


Multiple myeloma with intracranial extension and bilateral renal infiltration: A case report and review of the literature.

Zhang MJ, Su GH, Shen J, Liu FH, Xu YF, Zhang XL, Wang Q, Wang RH, Liu CY, Zhao YL.

Oncol Lett. 2015 Oct;10(4):2337-2340. Epub 2015 Aug 4.


Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation.

Peng J, Fullerton PT Jr, Monsivais D, Clementi C, Su GH, Matzuk MM.

Mol Endocrinol. 2015 Dec;29(12):1684-93. doi: 10.1210/me.2015-1048. Epub 2015 Oct 20.


Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.

Qiu W, Tang SM, Lee S, Turk AT, Sireci AN, Qiu A, Rose C, Xie C, Kitajewski J, Wen HJ, Crawford HC, Sims PA, Hruban RH, Remotti HE, Su GH.

Gastroenterology. 2016 Jan;150(1):218-228.e12. doi: 10.1053/j.gastro.2015.09.013. Epub 2015 Sep 25.


Effects of anthocyanins from purple sweet potato (Ipomoea batatas L. cultivar Eshu No. 8) on the serum uric acid level and xanthine oxidase activity in hyperuricemic mice.

Zhang ZC, Su GH, Luo CL, Pang YL, Wang L, Li X, Wen JH, Zhang JL.

Food Funct. 2015 Sep;6(9):3045-55. doi: 10.1039/c5fo00499c.


[Combined transgenic inhibition of CaMKII and Ik1 on cardiac remodeling].

Huang Y, Dai M, Du YM, Yao YF, Zhang JM, Su GH, Shu YW, Cui TP, Du XL, Li JD.

Sheng Li Xue Bao. 2015 Apr 25;67(2):201-6. Chinese.


Smad4 loss synergizes with TGFα overexpression in promoting pancreatic metaplasia, PanIN development, and fibrosis.

Garcia-Carracedo D, Yu CC, Akhavan N, Fine SA, Schönleben F, Maehara N, Karg DC, Xie C, Qiu W, Fine RL, Remotti HE, Su GH.

PLoS One. 2015 Mar 24;10(3):e0120851. doi: 10.1371/journal.pone.0120851. eCollection 2015.


Relationship between vitamin D (1,25-dihydroxyvitamin D3) receptor gene polymorphisms and primary biliary cirrhosis risk: a meta-analysis.

Fang F, Wang J, Pan J, Su GH, Xu LX, Li G.

Genet Mol Res. 2015 Feb 6;14(1):981-8. doi: 10.4238/2015.February.6.1.


Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia.

Tao YF, Xu LX, Lu J, Hu SY, Fang F, Cao L, Xiao PF, Du XJ, Sun LC, Li ZH, Wang NN, Su GH, Li YH, Li G, Zhao H, Li YP, Xu YY, Zhou HT, Wu Y, Jin MF, Liu L, Zhu XM, Ni J, Wang J, Xing F, Zhao WL, Pan J.

J Exp Clin Cancer Res. 2015 Jan 22;34:4. doi: 10.1186/s13046-014-0118-1.


Molecular targeting of the oncoprotein PLK1 in pediatric acute myeloid leukemia: RO3280, a novel PLK1 inhibitor, induces apoptosis in leukemia cells.

Wang NN, Li ZH, Zhao H, Tao YF, Xu LX, Lu J, Cao L, Du XJ, Sun LC, Zhao WL, Xiao PF, Fang F, Su GH, Li YH, Li G, Li YP, Xu YY, Zhou HT, Wu Y, Jin MF, Liu L, Ni J, Wang J, Hu SY, Zhu XM, Feng X, Pan J.

Int J Mol Sci. 2015 Jan 7;16(1):1266-92. doi: 10.3390/ijms16011266.


Parental health and social support in the first trimester of pregnancy and the risk of oral clefts: a questionnaire-based, case-control study.

Ma J, Huang YQ, Yao C, Ma SQ, Meng T, Ma M, Su GH, Zhai K, Zhou ZW, Zhu JF, Shi B.

Plast Reconstr Surg. 2015 Jan;135(1):212-8. doi: 10.1097/PRS.0000000000000778.


Zinc finger protein 382 is downregulated by promoter hypermethylation in pediatric acute myeloid leukemia patients.

Tao YF, Hu SY, Lu J, Cao L, Zhao WL, Xiao PF, Xu LX, Li ZH, Wang NN, Du XJ, Sun LC, Zhao H, Fang F, Su GH, Li YH, Li YP, Xu YY, Ni J, Wang J, Feng X, Pan J.

Int J Mol Med. 2014 Dec;34(6):1505-15. doi: 10.3892/ijmm.2014.1966. Epub 2014 Oct 13.


Elevated soluble ST2 and depression increased the risk of all-cause mortality and hospitalization in patients with heart failure.

Xu SD, Su GH, Lu YX, Shuai XX, Tao XF, Meng YD, Luo P.

Int Heart J. 2014;55(5):445-50. Epub 2014 Jul 28.


Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity.

Li WZ, Wang J, Long R, Su GH, Bukhory DK, Dai J, Jin N, Huang SY, Jia P, Li T, Fan C, Liu K, Wang Z.

PLoS One. 2014 Apr 11;9(4):e94551. doi: 10.1371/journal.pone.0094551. eCollection 2014.


MicroRNA-7a/b protects against cardiac myocyte injury in ischemia/reperfusion by targeting poly(ADP-ribose) polymerase.

Li B, Li R, Zhang C, Bian HJ, Wang F, Xiao J, Liu SW, Yi W, Zhang MX, Wang SX, Zhang Y, Su GH, Ji XP.

PLoS One. 2014 Mar 3;9(3):e90096. doi: 10.1371/journal.pone.0090096. eCollection 2014.


PIK3CA mutations in mucinous cystic neoplasms of the pancreas.

Garcia-Carracedo D, Chen ZM, Qiu W, Huang AS, Tang SM, Hruban RH, Su GH.

Pancreas. 2014 Mar;43(2):245-9. doi: 10.1097/MPA.0000000000000034.

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