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Items: 12

1.

Synthesis and SAR studies of novel benzodiazepinedione-based inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB).

Letourneau JJ, Stroke IL, Hilbert DW, Cole AG, Sturzenbecker LJ, Marinelli BA, Quintero JG, Sabalski J, Li Y, Ma L, Pechik I, Stein PD, Webb ML.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3601-3605. doi: 10.1016/j.bmcl.2018.10.047. Epub 2018 Oct 29.

PMID:
30392779
2.

Treatment of Clostridium difficile Infection with a Small-Molecule Inhibitor of Toxin UDP-Glucose Hydrolysis Activity.

Stroke IL, Letourneau JJ, Miller TE, Xu Y, Pechik I, Savoly DR, Ma L, Sturzenbecker LJ, Sabalski J, Stein PD, Webb ML, Hilbert DW.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e00107-18. doi: 10.1128/AAC.00107-18. Print 2018 May.

3.

Identification and initial optimization of inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB).

Letourneau JJ, Stroke IL, Hilbert DW, Sturzenbecker LJ, Marinelli BA, Quintero JG, Sabalski J, Ma L, Diller DJ, Stein PD, Webb ML.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):756-761. doi: 10.1016/j.bmcl.2018.01.005. Epub 2018 Jan 5.

PMID:
29331267
4.

Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha.

Tate BF, Allenby G, Janocha R, Kazmer S, Speck J, Sturzenbecker LJ, AbarzĂșa P, Levin AA, Grippo JF.

Mol Cell Biol. 1994 Apr;14(4):2323-30.

5.

RXR-dependent and RXR-independent transactivation by retinoic acid receptors.

SchrÀder M, Wyss A, Sturzenbecker LJ, Grippo JF, LeMotte P, Carlberg C.

Nucleic Acids Res. 1993 Mar 11;21(5):1231-7.

6.

Two nuclear signalling pathways for vitamin D.

Carlberg C, Bendik I, Wyss A, Meier E, Sturzenbecker LJ, Grippo JF, Hunziker W.

Nature. 1993 Feb 18;361(6413):657-60.

PMID:
8382345
7.

A new pathway for vitamin A. Understanding the pleiotropic effects of retinoids.

Levin AA, Sturzenbecker LJ, Kazmer S, Bosakowski T, Huselton C, Allenby G, Speck J, Kratzeisen C, Rosenberger M, Lovey A, et al.

Ann N Y Acad Sci. 1992 Sep 30;669:70-85; discussion 85-6. No abstract available.

PMID:
1332567
8.

9-cis retinoic acid stereoisomer binds and activates the nuclear receptor RXR alpha.

Levin AA, Sturzenbecker LJ, Kazmer S, Bosakowski T, Huselton C, Allenby G, Speck J, Kratzeisen C, Rosenberger M, Lovey A, et al.

Nature. 1992 Jan 23;355(6358):359-61.

PMID:
1309942
9.

Retinoic acid receptor belongs to a subclass of nuclear receptors that do not form "docking" complexes with hsp90.

Dalman FC, Sturzenbecker LJ, Levin AA, Lucas DA, Perdew GH, Petkovitch M, Chambon P, Grippo JF, Pratt WB.

Biochemistry. 1991 Jun 4;30(22):5605-8.

PMID:
1645195
10.

Complementary oligonucleotide sequence inhibits both Vmw65 gene expression and replication of herpes simplex virus.

Draper KG, Ceruzzi M, Kmetz ME, Sturzenbecker LJ.

Antiviral Res. 1990 Apr;13(4):151-64.

PMID:
2166465
11.
12.

The autonomous parvovirus MVM encodes two nonstructural proteins in addition to its capsid polypeptides.

Cotmore SF, Sturzenbecker LJ, Tattersall P.

Virology. 1983 Sep;129(2):333-43.

PMID:
6623929

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