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Items: 5


Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function.

Milasta S, Dillon CP, Sturm OE, Verbist KC, Brewer TL, Quarato G, Brown SA, Frase S, Janke LJ, Perry SS, Thomas PG, Green DR.

Immunity. 2016 Jan 19;44(1):88-102. doi: 10.1016/j.immuni.2015.12.002. Epub 2016 Jan 12.


The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier.

Sturm OE, Orton R, Grindlay J, Birtwistle M, Vyshemirsky V, Gilbert D, Calder M, Pitt A, Kholodenko B, Kolch W.

Sci Signal. 2010 Dec 21;3(153):ra90. doi: 10.1126/scisignal.2001212.


Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway.

Orton RJ, Adriaens ME, Gormand A, Sturm OE, Kolch W, Gilbert DR.

BMC Syst Biol. 2009 Oct 5;3:100. doi: 10.1186/1752-0509-3-100.


Computational modelling reveals feedback redundancy within the epidermal growth factor receptor/extracellular-signal regulated kinase signalling pathway.

Orton RJ, Sturm OE, Gormand A, Wolch W, Gilbert DR.

IET Syst Biol. 2008 Jul;2(4):173-83. doi: 10.1049/iet-syb:20070066.


Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway.

Orton RJ, Sturm OE, Vyshemirsky V, Calder M, Gilbert DR, Kolch W.

Biochem J. 2005 Dec 1;392(Pt 2):249-61. Review.

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