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Items: 1 to 50 of 229

1.

Rapid isolation of acidic cannabinoids from Cannabis sativa L. using pH-zone-refining centrifugal partition chromatography.

Popp JR, Petrakis EA, Angelis A, Halabalaki M, Bonn GK, Stuppner H, Skaltsounis LA.

J Chromatogr A. 2019 Aug 16;1599:196-202. doi: 10.1016/j.chroma.2019.04.048. Epub 2019 Apr 18.

PMID:
31027757
2.

A convenient workflow to spot photosensitizers revealed photo-activity in basidiomycetes.

Siewert B, Vrabl P, Hammerle F, Bingger I, Stuppner H.

RSC Adv. 2019 Feb 4;9(8):4545-4552. doi: 10.1039/c8ra10181g. Epub 2019 Feb 5.

3.

Development and Validation of a UHPLC-DAD Method for the Quantitative Analysis of Major Dihydrochalcone Glucosides from Thonningia sanguinea VAHL.

Pompermaier L, Schwaiger S, Mawunu M, Lautenschlaeger T, Stuppner H.

Planta Med. 2019 Mar 22. doi: 10.1055/a-0877-7255. [Epub ahead of print]

PMID:
30901776
4.

Eupatoriopicrin Inhibits Pro-inflammatory Functions of Neutrophils via Suppression of IL-8 and TNF-alpha Production and p38 and ERK 1/2 MAP Kinases.

Michalak B, Piwowarski JP, Granica S, Waltenberger B, Atanasov AG, Khan SY, Breuss JM, Uhrin P, Żyżyńska-Granica B, Stojakowska A, Stuppner H, Kiss AK.

J Nat Prod. 2019 Feb 22;82(2):375-385. doi: 10.1021/acs.jnatprod.8b00939. Epub 2019 Jan 17.

PMID:
30653318
5.

Mushroom Tyrosinase-Based Enzyme Inhibition Assays Are Not Suitable for Bioactivity-Guided Fractionation of Extracts.

Mayr F, Sturm S, Ganzera M, Waltenberger B, Martens S, Schwaiger S, Schuster D, Stuppner H.

J Nat Prod. 2019 Jan 25;82(1):136-147. doi: 10.1021/acs.jnatprod.8b00847. Epub 2019 Jan 10.

PMID:
30629444
6.

HPTLC Autography Based Screening and Isolation of Mushroom Tyrosinase Inhibitors of European Plant Species.

Revoltella S, Rainer B, Waltenberger B, Pagitz K, Schwaiger S, Stuppner H.

Chem Biodivers. 2019 Mar;16(3):e1800541. doi: 10.1002/cbdv.201800541. Epub 2019 Feb 14.

PMID:
30556957
7.

Early inhibition of endothelial retinoid uptake upon myocardial infarction restores cardiac function and prevents cell, tissue, and animal death.

Danzl K, Messner B, Doppler C, Nebert C, Abfalterer A, Sakic A, Temml V, Heinz K, Streitwieser R, Edelmann T, Mairhofer M, Grimm M, Laufer G, Zierer A, Stuppner H, Schuster D, Ploner C, Müller T, Bernhard D.

J Mol Cell Cardiol. 2019 Jan;126:105-117. doi: 10.1016/j.yjmcc.2018.11.012. Epub 2018 Nov 23.

8.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):248-249. doi: 10.1039/c8np90041h. Epub 2018 Nov 23.

9.

Phytochemical and Analytical Characterization of Novel Sulfated Coumarins in the Marine Green Macroalga Dasycladus vermicularis (Scopoli) Krasser.

Hartmann A, Ganzera M, Karsten U, Skhirtladze A, Stuppner H.

Molecules. 2018 Oct 23;23(11). pii: E2735. doi: 10.3390/molecules23112735.

10.

Secondary metabolites from lichen as potent inhibitors of advanced glycation end products and vasodilative agents.

Schinkovitz A, Le Pogam P, Derbré S, Roy-Vessieres E, Blanchard P, Thirumaran SL, Breard D, Aumond MC, Zehl M, Urban E, Kaur A, Jäger N, Hofer S, Kopp B, Stuppner H, Baglin I, Seraphin D, Tomasi S, Henrion D, Boustie J, Richomme P.

Fitoterapia. 2018 Nov;131:182-188. doi: 10.1016/j.fitote.2018.10.015. Epub 2018 Oct 16.

PMID:
30339926
11.

Seasonal variation in the chemical composition of two chemotypes of Lippia alba.

Gomes AF, Almeida MP, Leite MF, Schwaiger S, Stuppner H, Halabalaki M, Amaral JG, David JM.

Food Chem. 2019 Feb 1;273:186-193. doi: 10.1016/j.foodchem.2017.11.089. Epub 2017 Nov 23.

PMID:
30292367
12.

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.

Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A.

Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5.

13.

Dihydrochalcone Glucosides from the Subaerial Parts of Thonningia sanguinea and Their in Vitro PTP1B Inhibitory Activities.

Pompermaier L, Heiss EH, Alilou M, Mayr F, Monizi M, Lautenschlaeger T, Schuster D, Schwaiger S, Stuppner H.

J Nat Prod. 2018 Sep 28;81(9):2091-2100. doi: 10.1021/acs.jnatprod.8b00450. Epub 2018 Sep 12.

PMID:
30207720
14.

Inhibition of Pro-Inflammatory Functions of Human Neutrophils by Constituents of Melodorum fruticosum Leaves.

Engels NS, Waltenberger B, Michalak B, Huynh L, Tran H, Kiss AK, Stuppner H.

Chem Biodivers. 2018 Nov;15(11):e1800269. doi: 10.1002/cbdv.201800269. Epub 2018 Nov 15.

15.

Development and validation of a rapid ultra-high performance liquid chromatography diode array detector method for Verbena officinalis L.

Gibitz-Eisath N, Eichberger M, Gruber R, Sturm S, Stuppner H.

J Pharm Biomed Anal. 2018 Oct 25;160:160-167. doi: 10.1016/j.jpba.2018.07.047. Epub 2018 Jul 27.

PMID:
30096646
16.

Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.

Cheung SY, Werner M, Esposito L, Troisi F, Cantone V, Liening S, König S, Gerstmeier J, Koeberle A, Bilancia R, Rizza R, Rossi A, Roviezzo F, Temml V, Schuster D, Stuppner H, Schubert-Zsilavecz M, Werz O, Hanke T, Pace S.

Eur J Med Chem. 2018 Aug 5;156:815-830. doi: 10.1016/j.ejmech.2018.07.031. Epub 2018 Jul 25.

PMID:
30053720
17.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Erratum in: Nat Prod Rep. 2018 Nov 23;:.

18.

In vitro metabolism of selected bioactive compounds of Eurycoma longifolia root extract to identify suitable markers in doping control.

Bräuer P, Anielski P, Schwaiger S, Stuppner H, Tran TVA, Vollmer G, Zierau O, Thieme D, Keiler AM.

Drug Test Anal. 2019 Jan;11(1):86-94. doi: 10.1002/dta.2449. Epub 2018 Aug 9.

PMID:
29975460
19.

Higher spermidine intake is linked to lower mortality: a prospective population-based study.

Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, Werner P, Ruckenstuhl C, Iglseder B, Weger S, Mairhofer B, Gartner M, Kedenko L, Chmelikova M, Stekovic S, Stuppner H, Oberhollenzer F, Kroemer G, Mayr M, Eisenberg T, Tilg H, Madeo F, Willeit J.

Am J Clin Nutr. 2018 Aug 1;108(2):371-380. doi: 10.1093/ajcn/nqy102.

PMID:
29955838
20.

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins.

Heilos D, Röhrl C, Pirker C, Englinger B, Baier D, Mohr T, Schwaiger M, Iqbal SM, van Schoonhoven S, Klavins K, Eberhart T, Windberger U, Taibon J, Sturm S, Stuppner H, Koellensperger G, Dornetshuber-Fleiss R, Jäger W, Lemmens-Gruber R, Berger W.

Oncotarget. 2018 May 22;9(39):25661-25680. doi: 10.18632/oncotarget.25432. eCollection 2018 May 22.

21.

Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources-The MediHealth Project.

Waltenberger B, Halabalaki M, Schwaiger S, Adamopoulos N, Allouche N, Fiebich BL, Hermans N, Jansen-Dürr P, Kesternich V, Pieters L, Schönbichler S, Skaltsounis AL, Tran H, Trougakos IP, Viljoen A, Wolfender JL, Wolfrum C, Xynos N, Stuppner H.

Molecules. 2018 May 6;23(5). pii: E1097. doi: 10.3390/molecules23051097.

22.

Immunomodulatory Effects of Diterpene Quinone Derivatives from the Roots of Horminum pyrenaicum in Human PBMC.

Becker K, Schwaiger S, Waltenberger B, Fuchs D, Pezzei CK, Schennach H, Stuppner H, Gostner JM.

Oxid Med Cell Longev. 2018 Jan 14;2018:2980295. doi: 10.1155/2018/2980295. eCollection 2018.

23.

Identification of the NADPH Oxidase 4 Inhibiting Principle of Lycopus europaeus.

Revoltella S, Baraldo G, Waltenberger B, Schwaiger S, Kofler P, Moesslacher J, Huber-Seidel A, Pagitz K, Kohl R, Jansen-Duerr P, Stuppner H.

Molecules. 2018 Mar 14;23(3). pii: E653. doi: 10.3390/molecules23030653.

24.

Tyrosinase Inhibitors from the Aerial Parts of Wulfenia carinthiaca Jacq.

Mutschlechner B, Rainer B, Schwaiger S, Stuppner H.

Chem Biodivers. 2018 Apr;15(4):e1800014. doi: 10.1002/cbdv.201800014. Epub 2018 Apr 17.

25.

Constituents of Mediterranean Spices Counteracting Vascular Smooth Muscle Cell Proliferation: Identification and Characterization of Rosmarinic Acid Methyl Ester as a Novel Inhibitor.

Liu R, Heiss EH, Waltenberger B, Blažević T, Schachner D, Jiang B, Krystof V, Liu W, Schwaiger S, Peña-Rodríguez LM, Breuss JM, Stuppner H, Dirsch VM, Atanasov AG.

Mol Nutr Food Res. 2018 Apr;62(7):e1700860. doi: 10.1002/mnfr.201700860. Epub 2018 Mar 30.

PMID:
29405576
26.

Medicinal plants of northern Angola and their anti-inflammatory properties.

Pompermaier L, Marzocco S, Adesso S, Monizi M, Schwaiger S, Neinhuis C, Stuppner H, Lautenschläger T.

J Ethnopharmacol. 2018 Apr 24;216:26-36. doi: 10.1016/j.jep.2018.01.019. Epub 2018 Feb 3.

PMID:
29355707
27.

Capillary electrophoresis as a fast and efficient alternative for the analysis of Urceola rosea leaf extracts.

Gufler V, Ngoc HN, Stuppner H, Ganzera M.

Fitoterapia. 2018 Mar;125:1-5. doi: 10.1016/j.fitote.2017.12.007. Epub 2017 Dec 8.

PMID:
29229419
28.

Development of a selective HPLC-DAD/ELSD method for the qualitative and quantitative assessment of commercially available Eurycoma longifolia products and plant extracts.

Mutschlechner B, Schwaiger S, Tran TVA, Stuppner H.

Fitoterapia. 2018 Jan;124:188-192. doi: 10.1016/j.fitote.2017.11.015. Epub 2017 Nov 14.

PMID:
29154863
29.

Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level.

Malainer C, Schachner D, Sangiovanni E, Atanasov AG, Schwaiger S, Stuppner H, Heiss EH, Dirsch VM.

J Nat Prod. 2017 Dec 22;80(12):3186-3193. doi: 10.1021/acs.jnatprod.7b00503. Epub 2017 Nov 17.

30.

Phytochemical and analytical characterization of constituents in Urceola rosea (Hook. & Arn.) D.J. Middleton leaves.

Nguyen Ngoc H, Nghiem DT, Pham TLG, Stuppner H, Ganzera M.

J Pharm Biomed Anal. 2018 Feb 5;149:66-69. doi: 10.1016/j.jpba.2017.10.031. Epub 2017 Oct 28.

PMID:
29101817
31.

Metabolomic analysis-Addressing NMR and LC-MS related problems in human feces sample preparation.

Moosmang S, Pitscheider M, Sturm S, Seger C, Tilg H, Halabalaki M, Stuppner H.

Clin Chim Acta. 2019 Feb;489:169-176. doi: 10.1016/j.cca.2017.10.029. Epub 2017 Oct 31.

PMID:
29097223
32.

Linked magnolol dimer as a selective PPARγ agonist - Structure-based rational design, synthesis, and bioactivity evaluation.

Dreier D, Latkolik S, Rycek L, Schnürch M, Dymáková A, Atanasov AG, Ladurner A, Heiss EH, Stuppner H, Schuster D, Mihovilovic MD, Dirsch VM.

Sci Rep. 2017 Oct 20;7(1):13002. doi: 10.1038/s41598-017-12628-5.

33.

Supercritical Fluid Chromatography in Natural Product Analysis - An Update.

Gibitz Eisath N, Sturm S, Stuppner H.

Planta Med. 2018 Apr;84(6-07):361-371. doi: 10.1055/s-0037-1599461. Epub 2017 Sep 22. Review.

PMID:
28938494
34.

A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature.

Hochleitner J, Akram M, Ueberall M, Davis RA, Waltenberger B, Stuppner H, Sturm S, Ueberall F, Gostner JM, Schuster D.

Sci Rep. 2017 Aug 14;7(1):8071. doi: 10.1038/s41598-017-08404-0.

35.

Plant extracts and natural compounds used against UVB-induced photoaging.

Cavinato M, Waltenberger B, Baraldo G, Grade CVC, Stuppner H, Jansen-Dürr P.

Biogerontology. 2017 Aug;18(4):499-516. doi: 10.1007/s10522-017-9715-7. Epub 2017 Jul 12. Review.

36.
37.

Anti-Inflammatory and Anti-Oxidant Potential of the Root Extract and Constituents of Doronicum austriacum.

Marzocco S, Adesso S, Alilou M, Stuppner H, Schwaiger S.

Molecules. 2017 Jun 16;22(6). pii: E1003. doi: 10.3390/molecules22061003.

38.

Aristolic Acid Derivatives from the Bark of Antidesma ghaesembilla.

Schäfer S, Schwaiger S, Stuppner H.

Planta Med. 2017 Aug;83(12-13):1097-1102. doi: 10.1055/s-0043-110141. Epub 2017 May 12.

PMID:
28499305
39.

Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.

Vuorinen A, Engeli RT, Leugger S, Bachmann F, Akram M, Atanasov AG, Waltenberger B, Temml V, Stuppner H, Krenn L, Ateba SB, Njamen D, Davis RA, Odermatt A, Schuster D.

J Nat Prod. 2017 Apr 28;80(4):965-974. doi: 10.1021/acs.jnatprod.6b00950. Epub 2017 Mar 20.

40.

Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening.

Temml V, Garscha U, Romp E, Schubert G, Gerstmeier J, Kutil Z, Matuszczak B, Waltenberger B, Stuppner H, Werz O, Schuster D.

Sci Rep. 2017 Feb 20;7:42751. doi: 10.1038/srep42751.

41.

Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin.

Khan SY, Awad EM, Oszwald A, Mayr M, Yin X, Waltenberger B, Stuppner H, Lipovac M, Uhrin P, Breuss JM.

Sci Rep. 2017 Jan 3;7:39501. doi: 10.1038/srep39501.

42.

Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase.

Peduto A, Scuotto M, Krauth V, Roviezzo F, Rossi A, Temml V, Esposito V, Stuppner H, Schuster D, D'Agostino B, Schiraldi C, de Rosa M, Werz O, Filosa R.

Eur J Med Chem. 2017 Feb 15;127:715-726. doi: 10.1016/j.ejmech.2016.10.046. Epub 2016 Oct 22.

PMID:
27836196
43.

Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice.

Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, Heinz K, Arnhard K, Laufer G, Grimm M, Stuppner H, Oberacher H, Eller P, Ritsch A, Bernhard D.

J Mol Cell Cardiol. 2016 Oct;99:35-46. doi: 10.1016/j.yjmcc.2016.08.003. Epub 2016 Aug 3.

44.

Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors.

Alsabil K, Suor-Cherer S, Koeberle A, Viault G, Lavaud A, Temml V, Waltenberger B, Schuster D, Litaudon M, Lorkowski S, de Vaumas R, Helesbeux JJ, Guilet D, Stuppner H, Werz O, Seraphin D, Richomme P.

Planta Med. 2016 Jul;82(11-12):1110-6. doi: 10.1055/s-0042-108739. Epub 2016 Jun 10.

PMID:
27286327
45.

Characterization of the XIAP-Inhibiting Proanthocyanidin Fraction of the Aerial Parts of Ephedra sinica.

Schäfer S, Salcher S, Seiter M, Ranninger C, Möst M, Obexer P, Huber CG, Ausserlechner MJ, Schwaiger S, Stuppner H.

Planta Med. 2016 Jul;82(11-12):973-85. doi: 10.1055/s-0042-107253. Epub 2016 May 24.

PMID:
27220077
46.

Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages.

Wang L, Ladurner A, Latkolik S, Schwaiger S, Linder T, Hošek J, Palme V, Schilcher N, Polanský O, Heiss EH, Stangl H, Mihovilovic MD, Stuppner H, Dirsch VM, Atanasov AG.

J Nat Prod. 2016 Jun 24;79(6):1651-7. doi: 10.1021/acs.jnatprod.6b00227. Epub 2016 May 24.

47.

The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.

Schaible AM, Filosa R, Krauth V, Temml V, Pace S, Garscha U, Liening S, Weinigel C, Rummler S, Schieferdecker S, Nett M, Peduto A, Collarile S, Scuotto M, Roviezzo F, Spaziano G, de Rosa M, Stuppner H, Schuster D, D'Agostino B, Werz O.

Biochem Pharmacol. 2016 Jul 15;112:60-71. doi: 10.1016/j.bcp.2016.04.019. Epub 2016 May 5.

PMID:
27157409
48.

Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project.

Waltenberger B, Atanasov AG, Heiss EH, Bernhard D, Rollinger JM, Breuss JM, Schuster D, Bauer R, Kopp B, Franz C, Bochkov V, Mihovilovic MD, Dirsch VM, Stuppner H.

Monatsh Chem. 2016;147:479-491. Epub 2016 Feb 25. Review.

49.

The Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ.

Papadakis ES, Barker CR, Syed H, Reeves T, Schwaiger S, Stuppner H, Troppmair J, Blaydes JP, Cutress RI.

Oncogenesis. 2016 Apr 4;5:e215. doi: 10.1038/oncsis.2016.10.

50.

A combination of trastuzumab and BAG-1 inhibition synergistically targets HER2 positive breast cancer cells.

Papadakis E, Robson N, Yeomans A, Bailey S, Laversin S, Beers S, Sayan AE, Ashton-Key M, Schwaiger S, Stuppner H, Troppmair J, Packham G, Cutress R.

Oncotarget. 2016 Apr 5;7(14):18851-64. doi: 10.18632/oncotarget.7944.

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