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Items: 1 to 50 of 80

1.

How Cells Respond to DNA Breaks in Mitosis.

Blackford AN, Stucki M.

Trends Biochem Sci. 2020 Jan 27. pii: S0968-0004(20)30008-6. doi: 10.1016/j.tibs.2019.12.010. [Epub ahead of print] Review.

PMID:
32001093
2.

Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.

Mooser C, Symeonidou IE, Leimbacher PA, Ribeiro A, Shorrocks AK, Jungmichel S, Larsen SC, Knechtle K, Jasrotia A, Zurbriggen D, Jeanrenaud A, Leikauf C, Fink D, Nielsen ML, Blackford AN, Stucki M.

Nat Commun. 2020 Jan 8;11(1):123. doi: 10.1038/s41467-019-13981-x.

3.

Decreasing Frontal Electroencephalogram Alpha Power and Increasing Sensitivity to Volatile Anesthetics Over 3 Surgeries Within 7 Months: A Case Report.

Kaiser HA, Hirschi T, Hartwich V, Stucki M, Rummel C, Reineke D, Hight D.

A A Pract. 2019 Oct 1;13(7):274-277. doi: 10.1213/XAA.0000000000001053.

PMID:
31274512
4.
5.

MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.

Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M.

Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18.

6.

NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.

Anand R, Jasrotia A, Bundschuh D, Howard SM, Ranjha L, Stucki M, Cejka P.

EMBO J. 2019 Apr 1;38(7). pii: e101005. doi: 10.15252/embj.2018101005. Epub 2019 Feb 20.

PMID:
30787182
7.

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

Lambert JP, Picaud S, Fujisawa T, Hou H, Savitsky P, Uusküla-Reimand L, Gupta GD, Abdouni H, Lin ZY, Tucholska M, Knight JDR, Gonzalez-Badillo B, St-Denis N, Newman JA, Stucki M, Pelletier L, Bandeira N, Wilson MD, Filippakopoulos P, Gingras AC.

Mol Cell. 2019 Feb 7;73(3):621-638.e17. doi: 10.1016/j.molcel.2018.11.006. Epub 2018 Dec 13.

8.

Short-term recovery pattern of plasma fibrinogen after cardiac surgery: A prospective observational study.

Erdoes G, Dietrich W, Stucki MP, Merz TM, Angelillo-Scherrer A, Nagler M, Carrel T, Eberle B.

PLoS One. 2018 Aug 3;13(8):e0201647. doi: 10.1371/journal.pone.0201647. eCollection 2018.

9.

Cerebral microembolism in the critically ill with acute kidney injury (COMET-AKI trial): study protocol for a randomized controlled clinical trial.

Erdoes G, Uehlinger DE, Kobel B, Stucki MP, Wiest R, Stueber F, Fankhauser N, Jakob SM, Schefold JC.

Trials. 2018 Mar 21;19(1):189. doi: 10.1186/s13063-018-2561-3.

10.

Spatially extended versus frontal cerebral near-infrared spectroscopy during cardiac surgery: a case series identifying potential advantages.

Rummel C, Basciani R, Nirkko A, Schroth G, Stucki M, Reineke D, Eberle B, Kaiser HA.

J Biomed Opt. 2018 Jan;23(1):1-11. doi: 10.1117/1.JBO.23.1.016012.

11.

Environmental Impacts and Hotspots of Food Losses: Value Chain Analysis of Swiss Food Consumption.

Beretta C, Stucki M, Hellweg S.

Environ Sci Technol. 2017 Oct 3;51(19):11165-11173. doi: 10.1021/acs.est.6b06179. Epub 2017 Sep 20.

PMID:
28862841
12.

Verification of effective Zika virus reduction by production steps used in the manufacture of plasma-derived medicinal products.

Roth NJ, Schäfer W, Popp B, Stucki M, Fang R.

Transfusion. 2017 Mar;57(3):720-721. doi: 10.1111/trf.14038. No abstract available.

PMID:
28297081
13.

C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells.

Gardiner JD, Abegglen LM, Huang X, Carter BE, Schackmann EA, Stucki M, Paxton CN, Lor Randall R, Amatruda JF, Putnam AR, Kovar H, Lessnick SL, Schiffman JD.

Oncotarget. 2017 Apr 18;8(16):26013-26026. doi: 10.18632/oncotarget.14847.

14.

Cerebral Microembolization During Aortic Valve Replacement Using Minimally Invasive or Conventional Extracorporeal Circulation: A Randomized Trial.

Basciani R, Kröninger F, Gygax E, Jenni H, Reineke D, Stucki M, Hagenbuch N, Carrel T, Eberle B, Erdoes G.

Artif Organs. 2016 Dec;40(12):E280-E291. doi: 10.1111/aor.12744. Epub 2016 Jun 10.

PMID:
27283935
15.

Hollow Silica as an Optically Transparent and Thermally Insulating Polymer Additive.

Ernawati L, Ogi T, Balgis R, Okuyama K, Stucki M, Hess SC, Stark WJ.

Langmuir. 2016 Jan 12;32(1):338-45. doi: 10.1021/acs.langmuir.5b04063. Epub 2015 Dec 21.

PMID:
26653274
16.

Nucleolar responses to DNA double-strand breaks.

Larsen DH, Stucki M.

Nucleic Acids Res. 2016 Jan 29;44(2):538-44. doi: 10.1093/nar/gkv1312. Epub 2015 Nov 28. Review.

17.

Technical Approach Determines Inflammatory Response after Surgical and Transcatheter Aortic Valve Replacement.

Erdoes G, Lippuner C, Kocsis I, Schiff M, Stucki M, Carrel T, Windecker S, Eberle B, Stueber F, Book M.

PLoS One. 2015 Nov 23;10(11):e0143089. doi: 10.1371/journal.pone.0143089. eCollection 2015.

18.

Expression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism.

Agca C, Boldt K, Gubler A, Meneau I, Corpet A, Samardzija M, Stucki M, Ueffing M, Grimm C.

BMC Biol. 2015 Apr 25;13:30. doi: 10.1186/s12915-015-0137-1.

19.

Secondary NAD+ deficiency in the inherited defect of glutamine synthetase.

Hu L, Ibrahim K, Stucki M, Frapolli M, Shahbeck N, Chaudhry FA, Görg B, Häussinger D, Penberthy WT, Ben-Omran T, Häberle J.

J Inherit Metab Dis. 2015 Nov;38(6):1075-83. doi: 10.1007/s10545-015-9846-4. Epub 2015 Apr 21.

PMID:
25896882
20.

TORC2 inhibition may boost DNA-damaging chemotherapy.

Stucki M.

Oncotarget. 2015 Jan 20;6(2):586-7.

21.

The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.

Larsen DH, Hari F, Clapperton JA, Gwerder M, Gutsche K, Altmeyer M, Jungmichel S, Toledo LI, Fink D, Rask MB, Grøfte M, Lukas C, Nielsen ML, Smerdon SJ, Lukas J, Stucki M.

Nat Cell Biol. 2014 Aug;16(8):792-803. doi: 10.1038/ncb3007. Epub 2014 Jul 27.

22.

Loss of ARID1A expression sensitizes cancer cells to PI3K- and AKT-inhibition.

Samartzis EP, Gutsche K, Dedes KJ, Fink D, Stucki M, Imesch P.

Oncotarget. 2014 Jul 30;5(14):5295-303.

23.

Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro.

Koppensteiner R, Samartzis EP, Noske A, von Teichman A, Dedes I, Gwerder M, Imesch P, Ikenberg K, Moch H, Fink D, Stucki M, Dedes KJ.

PLoS One. 2014 Jun 13;9(6):e100041. doi: 10.1371/journal.pone.0100041. eCollection 2014.

24.

Chromatin maintenance and dynamics in senescence: a spotlight on SAHF formation and the epigenome of senescent cells.

Corpet A, Stucki M.

Chromosoma. 2014 Oct;123(5):423-36. doi: 10.1007/s00412-014-0469-6. Epub 2014 May 27. Review.

25.
26.

Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism.

Coelho D, Kim JC, Miousse IR, Fung S, du Moulin M, Buers I, Suormala T, Burda P, Frapolli M, Stucki M, Nürnberg P, Thiele H, Robenek H, Höhne W, Longo N, Pasquali M, Mengel E, Watkins D, Shoubridge EA, Majewski J, Rosenblatt DS, Fowler B, Rutsch F, Baumgartner MR.

Nat Genet. 2012 Oct;44(10):1152-5. doi: 10.1038/ng.2386. Epub 2012 Aug 26.

PMID:
22922874
27.

3-methylcrotonyl-CoA carboxylase deficiency: clinical, biochemical, enzymatic and molecular studies in 88 individuals.

Grünert SC, Stucki M, Morscher RJ, Suormala T, Bürer C, Burda P, Christensen E, Ficicioglu C, Herwig J, Kölker S, Möslinger D, Pasquini E, Santer R, Schwab KO, Wilcken B, Fowler B, Yue WW, Baumgartner MR.

Orphanet J Rare Dis. 2012 May 29;7:31. doi: 10.1186/1750-1172-7-31.

28.

The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.

Jungmichel S, Clapperton JA, Lloyd J, Hari FJ, Spycher C, Pavic L, Li J, Haire LF, Bonalli M, Larsen DH, Lukas C, Lukas J, MacMillan D, Nielsen ML, Stucki M, Smerdon SJ.

Nucleic Acids Res. 2012 May;40(9):3913-28. doi: 10.1093/nar/gkr1300. Epub 2012 Jan 10.

29.

Molecular mechanisms leading to three different phenotypes in the cblD defect of intracellular cobalamin metabolism.

Stucki M, Coelho D, Suormala T, Burda P, Fowler B, Baumgartner MR.

Hum Mol Genet. 2012 Mar 15;21(6):1410-8. doi: 10.1093/hmg/ddr579. Epub 2011 Dec 8.

30.

Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells.

Toller IM, Neelsen KJ, Steger M, Hartung ML, Hottiger MO, Stucki M, Kalali B, Gerhard M, Sartori AA, Lopes M, Müller A.

Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14944-9. doi: 10.1073/pnas.1100959108. Epub 2011 Sep 6.

31.

The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage.

Larsen DH, Poinsignon C, Gudjonsson T, Dinant C, Payne MR, Hari FJ, Rendtlew Danielsen JM, Menard P, Sand JC, Stucki M, Lukas C, Bartek J, Andersen JS, Lukas J.

J Cell Biol. 2010 Sep 6;190(5):731-40. doi: 10.1083/jcb.200912135. Epub 2010 Aug 30.

32.

MDC1: The art of keeping things in focus.

Jungmichel S, Stucki M.

Chromosoma. 2010 Aug;119(4):337-49. doi: 10.1007/s00412-010-0266-9. Epub 2010 Mar 12. Review.

33.

A divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to damaged chromatin.

Hari FJ, Spycher C, Jungmichel S, Pavic L, Stucki M.

EMBO Rep. 2010 May;11(5):387-92. doi: 10.1038/embor.2010.30. Epub 2010 Mar 12.

34.

A novel mutation in LMBRD1 causes the cblF defect of vitamin B(12) metabolism in a Turkish patient.

Gailus S, Suormala T, Malerczyk-Aktas AG, Toliat MR, Wittkampf T, Stucki M, Nürnberg P, Fowler B, Hennermann JB, Rutsch F.

J Inherit Metab Dis. 2010 Feb;33(1):17-24. doi: 10.1007/s10545-009-9032-7. Epub 2010 Feb 3.

PMID:
20127417
35.

Cryptic exon activation by disruption of exon splice enhancer: novel mechanism causing 3-methylcrotonyl-CoA carboxylase deficiency.

Stucki M, Suormala T, Fowler B, Valle D, Baumgartner MR.

J Biol Chem. 2009 Oct 16;284(42):28953-7. doi: 10.1074/jbc.M109.050674. Epub 2009 Aug 24.

36.

Histone H2A.X Tyr142 phosphorylation: a novel sWItCH for apoptosis?

Stucki M.

DNA Repair (Amst). 2009 Jul 4;8(7):873-6. doi: 10.1016/j.dnarep.2009.04.003. Epub 2009 May 14.

PMID:
19446503
37.

Spectrum of mutations in MMACHC, allelic expression, and evidence for genotype-phenotype correlations.

Lerner-Ellis JP, Anastasio N, Liu J, Coelho D, Suormala T, Stucki M, Loewy AD, Gurd S, Grundberg E, Morel CF, Watkins D, Baumgartner MR, Pastinen T, Rosenblatt DS, Fowler B.

Hum Mutat. 2009 Jul;30(7):1072-81. doi: 10.1002/humu.21001.

PMID:
19370762
38.

Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism.

Rutsch F, Gailus S, Miousse IR, Suormala T, Sagné C, Toliat MR, Nürnberg G, Wittkampf T, Buers I, Sharifi A, Stucki M, Becker C, Baumgartner M, Robenek H, Marquardt T, Höhne W, Gasnier B, Rosenblatt DS, Fowler B, Nürnberg P.

Nat Genet. 2009 Feb;41(2):234-9. doi: 10.1038/ng.294. Epub 2009 Jan 11.

PMID:
19136951
39.

Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin.

Spycher C, Miller ES, Townsend K, Pavic L, Morrice NA, Janscak P, Stewart GS, Stucki M.

J Cell Biol. 2008 Apr 21;181(2):227-40. doi: 10.1083/jcb.200709008. Epub 2008 Apr 14.

40.

Gene identification for the cblD defect of vitamin B12 metabolism.

Coelho D, Suormala T, Stucki M, Lerner-Ellis JP, Rosenblatt DS, Newbold RF, Baumgartner MR, Fowler B.

N Engl J Med. 2008 Apr 3;358(14):1454-64. doi: 10.1056/NEJMoa072200.

41.

Investigations of prion and virus safety of a new liquid IVIG product.

Stucki M, Boschetti N, Schäfer W, Hostettler T, Käsermann F, Nowak T, Gröner A, Kempf C.

Biologicals. 2008 Jul;36(4):239-47. doi: 10.1016/j.biologicals.2008.01.004. Epub 2008 Mar 12.

PMID:
18337119
42.

Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.

Xie A, Hartlerode A, Stucki M, Odate S, Puget N, Kwok A, Nagaraju G, Yan C, Alt FW, Chen J, Jackson SP, Scully R.

Mol Cell. 2007 Dec 28;28(6):1045-57.

43.

DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.

Bartkova J, Horejsí Z, Sehested M, Nesland JM, Rajpert-De Meyts E, Skakkebaek NE, Stucki M, Jackson S, Lukas J, Bartek J.

Oncogene. 2007 Nov 22;26(53):7414-22. Epub 2007 Jun 4.

PMID:
17546051
44.

Pathogen inactivation and removal procedures used in the production of intravenous immunoglobulins.

Kempf C, Stucki M, Boschetti N.

Biologicals. 2007 Mar;35(1):35-42. Epub 2006 Apr 3.

PMID:
16581263
45.

Staphylococcus aureus CcpA affects virulence determinant production and antibiotic resistance.

Seidl K, Stucki M, Ruegg M, Goerke C, Wolz C, Harris L, Berger-Bächi B, Bischoff M.

Antimicrob Agents Chemother. 2006 Apr;50(4):1183-94.

46.

gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes.

Stucki M, Jackson SP.

DNA Repair (Amst). 2006 May 10;5(5):534-43. Epub 2006 Mar 10. Review.

PMID:
16531125
47.

Virus safety of intravenous immunoglobulin: future challenges.

Boschetti N, Stucki M, Späth PJ, Kempf C.

Clin Rev Allergy Immunol. 2005 Dec;29(3):333-44. Review.

PMID:
16391410
48.

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.

Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP.

Cell. 2005 Dec 29;123(7):1213-26. Erratum in: Cell. 2008 May 2;133(3):549.

49.

Tudor domains track down DNA breaks.

Stucki M, Jackson SP.

Nat Cell Biol. 2004 Dec;6(12):1150-2. No abstract available.

PMID:
15573092
50.

MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes.

Stucki M, Jackson SP.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):953-7. Review.

PMID:
15279781

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