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Items: 1 to 50 of 66

1.

αv Integrins regulate germinal center B cell responses through noncanonical autophagy.

Raso F, Sagadiev S, Du S, Gage E, Arkatkar T, Metzler G, Stuart LM, Orr MT, Rawlings DJ, Jackson SW, Lacy-Hulbert A, Acharya M.

J Clin Invest. 2018 Aug 31;128(9):4163-4178. doi: 10.1172/JCI99597. Epub 2018 Aug 20.

2.

Evaluation of MicroRNA Delivery In Vivo.

Brown RAM, Richardson KL, Kalinowski FC, Epis MR, Horsham JL, Kabir TD, De Pinho MH, Beveridge DJ, Stuart LM, Wintle LC, Leedman PJ.

Methods Mol Biol. 2018;1699:155-178. doi: 10.1007/978-1-4939-7435-1_12.

PMID:
29086376
3.

miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression.

Epis MR, Giles KM, Beveridge DJ, Richardson KL, Candy PA, Stuart LM, Bentel J, Cohen RJ, Leedman PJ.

Oncotarget. 2017 Jun 27;8(33):55116-55134. doi: 10.18632/oncotarget.18664. eCollection 2017 Aug 15.

4.

A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma.

Kabir TD, Ganda C, Brown RM, Beveridge DJ, Richardson KL, Chaturvedi V, Candy P, Epis M, Wintle L, Kalinowski F, Kopp C, Stuart LM, Yeoh GC, George J, Leedman PJ.

Hepatology. 2018 Jan;67(1):216-231. doi: 10.1002/hep.29478. Epub 2017 Nov 29.

PMID:
28833396
5.

GOP-1: Helping phagosomes pass the acid test.

Stuart LM, Lacy-Hulbert A.

J Cell Biol. 2017 Jun 5;216(6):1517-1519. doi: 10.1083/jcb.201704047. Epub 2017 May 24.

6.

β8 Integrin Expression and Activation of TGF-β by Intestinal Dendritic Cells Are Determined by Both Tissue Microenvironment and Cell Lineage.

Boucard-Jourdin M, Kugler D, Endale Ahanda ML, This S, De Calisto J, Zhang A, Mora JR, Stuart LM, Savill J, Lacy-Hulbert A, Paidassi H.

J Immunol. 2016 Sep 1;197(5):1968-78. doi: 10.4049/jimmunol.1600244. Epub 2016 Aug 1.

7.

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.

Giles KM, Brown RA, Ganda C, Podgorny MJ, Candy PA, Wintle LC, Richardson KL, Kalinowski FC, Stuart LM, Epis MR, Haass NK, Herlyn M, Leedman PJ.

Oncotarget. 2016 May 31;7(22):31663-80. doi: 10.18632/oncotarget.9421.

8.

αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.

Acharya M, Sokolovska A, Tam JM, Conway KL, Stefani C, Raso F, Mukhopadhyay S, Feliu M, Paul E, Savill J, Hynes RO, Xavier RJ, Vyas JM, Stuart LM, Lacy-Hulbert A.

Nat Commun. 2016 Mar 11;7:10917. doi: 10.1038/ncomms10917.

9.

De-Mst-ifying microbicidal killing.

Stuart LM, Lacy-Hulbert A.

Nat Immunol. 2015 Nov;16(11):1107-8. doi: 10.1038/ni.3291. No abstract available.

PMID:
26482969
10.

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia.

Diabate M, Munro P, Garcia E, Jacquel A, Michel G, Obba S, Goncalves D, Luci C, Marchetti S, Demon D, Degos C, Bechah Y, Mege JL, Lamkanfi M, Auberger P, Gorvel JP, Stuart LM, Landraud L, Lemichez E, Boyer L.

PLoS Pathog. 2015 Mar 17;11(3):e1004732. doi: 10.1371/journal.ppat.1004732. eCollection 2015 Mar.

11.

Tuberculosis vaccines: barriers and prospects on the quest for a transformative tool.

Karp CL, Wilson CB, Stuart LM.

Immunol Rev. 2015 Mar;264(1):363-81. doi: 10.1111/imr.12270. Review.

12.

Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes.

Visvikis O, Ihuegbu N, Labed SA, Luhachack LG, Alves AF, Wollenberg AC, Stuart LM, Stormo GD, Irazoqui JE.

Immunity. 2014 Jun 19;40(6):896-909. doi: 10.1016/j.immuni.2014.05.002. Epub 2014 May 29.

13.

Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages.

Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xavier RJ, Vyas JM.

J Infect Dis. 2014 Dec 1;210(11):1844-54. doi: 10.1093/infdis/jiu290. Epub 2014 May 19.

14.

Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib.

Giles KM, Kalinowski FC, Candy PA, Epis MR, Zhang PM, Redfern AD, Stuart LM, Goodall GJ, Leedman PJ.

Mol Cancer Ther. 2013 Nov;12(11):2541-58. doi: 10.1158/1535-7163.MCT-13-0170. Epub 2013 Sep 11.

15.

Out of context: clinical practice guidelines and patients with multiple chronic conditions: a systematic review.

Wyatt KD, Stuart LM, Brito JP, Carranza Leon B, Domecq JP, Prutsky GJ, Egginton JS, Calvin AD, Shah ND, Murad MH, Montori VM.

Med Care. 2014 Mar;52 Suppl 3:S92-S100. doi: 10.1097/MLR.0b013e3182a51b3d. Review.

PMID:
23969592
16.

Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients.

Candy PA, Phillips MR, Redfern AD, Colley SM, Davidson JA, Stuart LM, Wood BA, Zeps N, Leedman PJ.

Br J Cancer. 2013 Aug 20;109(4):1023-30. doi: 10.1038/bjc.2013.431. Epub 2013 Jul 30.

17.

Natural selection in a bangladeshi population from the cholera-endemic ganges river delta.

Karlsson EK, Harris JB, Tabrizi S, Rahman A, Shlyakhter I, Patterson N, O'Dushlaine C, Schaffner SF, Gupta S, Chowdhury F, Sheikh A, Shin OS, Ellis C, Becker CE, Stuart LM, Calderwood SB, Ryan ET, Qadri F, Sabeti PC, Larocque RC.

Sci Transl Med. 2013 Jul 3;5(192):192ra86. doi: 10.1126/scitranslmed.3006338.

18.

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.

Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, Becker CE, Ediriweera HN, Mullick AE, Golenbock DT, Stuart LM, Latz E, Fitzgerald KA, Moore KJ.

Nat Immunol. 2013 Aug;14(8):812-20. doi: 10.1038/ni.2639. Epub 2013 Jun 30.

19.

RhoGTPases--NODes for effector-triggered immunity in animals.

Stuart LM, Boyer L.

Cell Res. 2013 Aug;23(8):980-1. doi: 10.1038/cr.2013.68. Epub 2013 May 21.

20.

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function.

Sokolovska A, Becker CE, Ip WK, Rathinam VA, Brudner M, Paquette N, Tanne A, Vanaja SK, Moore KJ, Fitzgerald KA, Lacy-Hulbert A, Stuart LM.

Nat Immunol. 2013 Jun;14(6):543-53. doi: 10.1038/ni.2595. Epub 2013 May 5.

21.

Dectin-1 activation controls maturation of β-1,3-glucan-containing phagosomes.

Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, Vyas JM.

J Biol Chem. 2013 May 31;288(22):16043-54. doi: 10.1074/jbc.M113.473223. Epub 2013 Apr 22.

22.

RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators.

Redfern AD, Colley SM, Beveridge DJ, Ikeda N, Epis MR, Li X, Foulds CE, Stuart LM, Barker A, Russell VJ, Ramsay K, Kobelke SJ, Li X, Hatchell EC, Payne C, Giles KM, Messineo A, Gatignol A, Lanz RB, O'Malley BW, Leedman PJ.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6536-41. doi: 10.1073/pnas.1301620110. Epub 2013 Apr 2.

23.

Effector-triggered versus pattern-triggered immunity: how animals sense pathogens.

Stuart LM, Paquette N, Boyer L.

Nat Rev Immunol. 2013 Mar;13(3):199-206. doi: 10.1038/nri3398. Epub 2013 Feb 15. Review.

24.

Measurement of phagocytosis, phagosome acidification, and intracellular killing of Staphylococcus aureus.

Sokolovska A, Becker CE, Stuart LM.

Curr Protoc Immunol. 2012 Nov;Chapter 14:Unit14.30. doi: 10.1002/0471142735.im1430s99.

PMID:
23129153
25.

TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.

Rathinam VA, Vanaja SK, Waggoner L, Sokolovska A, Becker C, Stuart LM, Leong JM, Fitzgerald KA.

Cell. 2012 Aug 3;150(3):606-19. doi: 10.1016/j.cell.2012.07.007. Epub 2012 Jul 19.

26.

EGL-9 controls C. elegans host defense specificity through prolyl hydroxylation-dependent and -independent HIF-1 pathways.

Luhachack LG, Visvikis O, Wollenberg AC, Lacy-Hulbert A, Stuart LM, Irazoqui JE.

PLoS Pathog. 2012;8(7):e1002798. doi: 10.1371/journal.ppat.1002798. Epub 2012 Jul 5.

27.

Penetration resistance: PKR's other talent.

Lacy-Hulbert A, Stuart LM.

Immunity. 2012 May 25;36(5):695-6. doi: 10.1016/j.immuni.2012.05.010.

28.

Clinical review. Risk factors for low bone mass-related fractures in men: a systematic review and meta-analysis.

Drake MT, Murad MH, Mauck KF, Lane MA, Undavalli C, Elraiyah T, Stuart LM, Prasad C, Shahrour A, Mullan RJ, Hazem A, Erwin PJ, Montori VM.

J Clin Endocrinol Metab. 2012 Jun;97(6):1861-70. doi: 10.1210/jc.2011-3058. Epub 2012 Mar 30. Review.

PMID:
22466344
29.

Clinical review. Comparative effectiveness of drug treatments to prevent fragility fractures: a systematic review and network meta-analysis.

Murad MH, Drake MT, Mullan RJ, Mauck KF, Stuart LM, Lane MA, Abu Elnour NO, Erwin PJ, Hazem A, Puhan MA, Li T, Montori VM.

J Clin Endocrinol Metab. 2012 Jun;97(6):1871-80. doi: 10.1210/jc.2011-3060. Review.

PMID:
22466336
30.

Apoptotic cells can deliver chemotherapeutics to engulfing macrophages and suppress inflammatory cytokine production.

Perez B, Paquette N, Païdassi H, Zhai B, White K, Skvirsky R, Lacy-Hulbert A, Stuart LM.

J Biol Chem. 2012 May 4;287(19):16029-36. doi: 10.1074/jbc.M112.340489. Epub 2012 Mar 20.

31.

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques.

van Gils JM, Derby MC, Fernandes LR, Ramkhelawon B, Ray TD, Rayner KJ, Parathath S, Distel E, Feig JL, Alvarez-Leite JI, Rayner AJ, McDonald TO, O'Brien KD, Stuart LM, Fisher EA, Lacy-Hulbert A, Moore KJ.

Nat Immunol. 2012 Jan 8;13(2):136-43. doi: 10.1038/ni.2205.

32.

Bacterial effectors: learning on the fly.

Boyer L, Paquette N, Silverman N, Stuart LM.

Adv Exp Med Biol. 2012;710:29-36. doi: 10.1007/978-1-4419-5638-5_4. Review.

33.

Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway.

Boyer L, Magoc L, Dejardin S, Cappillino M, Paquette N, Hinault C, Charriere GM, Ip WK, Fracchia S, Hennessy E, Erturk-Hasdemir D, Reichhart JM, Silverman N, Lacy-Hulbert A, Stuart LM.

Immunity. 2011 Oct 28;35(4):536-49. doi: 10.1016/j.immuni.2011.08.015. Epub 2011 Oct 20.

34.

Preferential expression of integrin αvβ8 promotes generation of regulatory T cells by mouse CD103+ dendritic cells.

Païdassi H, Acharya M, Zhang A, Mukhopadhyay S, Kwon M, Chow C, Stuart LM, Savill J, Lacy-Hulbert A.

Gastroenterology. 2011 Nov;141(5):1813-20. doi: 10.1053/j.gastro.2011.06.076. Epub 2011 Jul 13.

35.

αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.

Acharya M, Mukhopadhyay S, Païdassi H, Jamil T, Chow C, Kissler S, Stuart LM, Hynes RO, Lacy-Hulbert A.

J Clin Invest. 2010 Dec;120(12):4445-52. doi: 10.1172/JCI43796. Epub 2010 Nov 22.

36.

Phagocytosis and phagosome acidification are required for pathogen processing and MyD88-dependent responses to Staphylococcus aureus.

Ip WK, Sokolovska A, Charriere GM, Boyer L, Dejardin S, Cappillino MP, Yantosca LM, Takahashi K, Moore KJ, Lacy-Hulbert A, Stuart LM.

J Immunol. 2010 Jun 15;184(12):7071-81. doi: 10.4049/jimmunol.1000110. Epub 2010 May 17.

37.

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters.

Charrière GM, Ip WE, Dejardin S, Boyer L, Sokolovska A, Cappillino MP, Cherayil BJ, Podolsky DK, Kobayashi KS, Silverman N, Lacy-Hulbert A, Stuart LM.

J Biol Chem. 2010 Jun 25;285(26):20147-54. doi: 10.1074/jbc.M110.115584. Epub 2010 Apr 20.

38.

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.

Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ.

Nat Immunol. 2010 Feb;11(2):155-61. doi: 10.1038/ni.1836. Epub 2009 Dec 27.

39.

Mannose-binding lectin and innate immunity.

Ip WK, Takahashi K, Ezekowitz RA, Stuart LM.

Immunol Rev. 2009 Jul;230(1):9-21. doi: 10.1111/j.1600-065X.2009.00789.x. Review.

PMID:
19594626
40.

Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination.

Guttormsen HK, Stuart LM, Shi L, Carroll MC, Chen J, Kasper DL, Ezekowitz RA, Takahashi K.

Clin Immunol. 2009 Mar;130(3):264-71. doi: 10.1016/j.clim.2008.09.012. Epub 2008 Nov 8.

41.

Influence of age on the association of retinol-binding protein 4 with metabolic syndrome.

Gavi S, Qurashi S, Stuart LM, Lau R, Melendez MM, Mynarcik DC, McNurlan MA, Gelato MC.

Obesity (Silver Spring). 2008 Apr;16(4):893-5. doi: 10.1038/oby.2007.138. Epub 2008 Jan 31.

42.

Phagocytosis and comparative innate immunity: learning on the fly.

Stuart LM, Ezekowitz RA.

Nat Rev Immunol. 2008 Feb;8(2):131-41. doi: 10.1038/nri2240. Review.

PMID:
18219310
43.

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.

Ip WK, Takahashi K, Moore KJ, Stuart LM, Ezekowitz RA.

J Exp Med. 2008 Jan 21;205(1):169-81. doi: 10.1084/jem.20071164. Epub 2008 Jan 7.

44.

CD36 signals to the actin cytoskeleton and regulates microglial migration via a p130Cas complex.

Stuart LM, Bell SA, Stewart CR, Silver JM, Richard J, Goss JL, Tseng AA, Zhang A, El Khoury JB, Moore KJ.

J Biol Chem. 2007 Sep 14;282(37):27392-401. Epub 2007 Jul 9.

45.

Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes.

Gavi S, Stuart LM, Kelly P, Melendez MM, Mynarcik DC, Gelato MC, McNurlan MA.

J Clin Endocrinol Metab. 2007 May;92(5):1886-90. Epub 2007 Feb 13.

PMID:
17299074
46.

A systems biology analysis of the Drosophila phagosome.

Stuart LM, Boulais J, Charriere GM, Hennessy EJ, Brunet S, Jutras I, Goyette G, Rondeau C, Letarte S, Huang H, Ye P, Morales F, Kocks C, Bader JS, Desjardins M, Ezekowitz RA.

Nature. 2007 Jan 4;445(7123):95-101. Epub 2006 Dec 6.

PMID:
17151602
47.

Requirements for apoptotic cell contact in regulation of macrophage responses.

Lucas M, Stuart LM, Zhang A, Hodivala-Dilke K, Febbraio M, Silverstein R, Savill J, Lacy-Hulbert A.

J Immunol. 2006 Sep 15;177(6):4047-54.

48.

SLIRP, a small SRA binding protein, is a nuclear receptor corepressor.

Hatchell EC, Colley SM, Beveridge DJ, Epis MR, Stuart LM, Giles KM, Redfern AD, Miles LE, Barker A, MacDonald LM, Arthur PG, Lui JC, Golding JL, McCulloch RK, Metcalf CB, Wilce JA, Wilce MC, Lanz RB, O'Malley BW, Leedman PJ.

Mol Cell. 2006 Jun 9;22(5):657-68.

49.

Collectins: opsonins for apoptotic cells and regulators of inflammation.

Stuart LM, Henson PM, Vandivier RW.

Curr Dir Autoimmun. 2006;9:143-61. Review.

PMID:
16394659
50.

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila.

Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Rämet M, Ezekowitz RA.

Cell. 2005 Oct 21;123(2):335-46.

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