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Metabolomic tools used in marine natural product drug discovery.

Stuart KA, Welsh K, Walker MC, Edrada-Ebel R.

Expert Opin Drug Discov. 2020 Feb 6:1-24. doi: 10.1080/17460441.2020.1722636. [Epub ahead of print]


Complete Genome Sequence of Escherichia coli Antibiotic-Resistant Isolate AR Bank #0349.

Stuart KL, Shore SM, Nicholson TL.

Microbiol Resour Announc. 2019 Nov 27;8(48). pii: e01078-19. doi: 10.1128/MRA.01078-19.


BCG revaccination boosts adaptive polyfunctional Th1/Th17 and innate effectors in IGRA+ and IGRA- Indian adults.

Rakshit S, Ahmed A, Adiga V, Sundararaj BK, Sahoo PN, Kenneth J, D'Souza G, Bonam W, Johnson C, Franken KL, Ottenhoff TH, Finak G, Gottardo R, Stuart KD, De Rosa SC, McElrath MJ, Vyakarnam A.

JCI Insight. 2019 Dec 19;4(24). pii: 130540. doi: 10.1172/jci.insight.130540.


Plasmodium Secretion Induces Hepatocyte Lysosome Exocytosis and Promotes Parasite Entry.

Vijayan K, Cestari I, Mast FD, Glennon EKK, McDermott SM, Kain HS, Brokaw AM, Aitchison JD, Stuart K, Kaushansky A.

iScience. 2019 Nov 22;21:603-611. doi: 10.1016/j.isci.2019.10.054. Epub 2019 Oct 31.


Chemoprophylaxis vaccination: Phase 1 study to explore stage-specific immunity to Plasmodium falciparum in U.S. adults.

Healy SA, Murphy SC, Hume JCC, Shelton L, Kuntz S, Van Voorhis WC, Moodie Z, Metch B, Wang R, Silver-Brace T, Fishbaugher M, Kennedy M, Finney OC, Chaturvedi R, Hobbs CV, Warner-Lubin M, Talley AK, Wong-Madden S, Stuart K, Wald A, Kappe SH, Kublin JG, Duffy PE.

Clin Infect Dis. 2019 Oct 17. pii: ciz1010. doi: 10.1093/cid/ciz1010. [Epub ahead of print]


Gynaecomastia caused by a feminizing adrenal tumour.

Gibbons SM, Jassam N, Abbas A, Stuart K, Fairhurst A, Barth JH.

Ann Clin Biochem. 2020 Jan;57(1):99-101. doi: 10.1177/0004563219884960. Epub 2019 Nov 4. No abstract available.


Radiation-induced oesophagitis in breast cancer: Factors influencing onset and severity for patients receiving supraclavicular nodal irradiation.

West K, Schneider M, Wright C, Beldham-Collins R, Coburn N, Tiver K, Gebski V, Stuart KE.

J Med Imaging Radiat Oncol. 2020 Feb;64(1):113-119. doi: 10.1111/1754-9485.12943. Epub 2019 Sep 4.


Clinically Significant Fibrosis Is Associated With Longitudinal Increases in Fibrosis-4 and Nonalcoholic Fatty Liver Disease Fibrosis Scores.

Patel PJ, Cheng JC, Banh X, Gracen L, Radford-Smith D, Hossain F, Horsfall LU, Hayward KL, Williams S, Johnson T, Brown NN, Saad N, Stuart KA, Russell AW, Valery PC, Clouston AD, Irvine KM, Bernard A, Powell EE.

Clin Gastroenterol Hepatol. 2020 Mar;18(3):710-718.e4. doi: 10.1016/j.cgh.2019.07.036. Epub 2019 Jul 25.


Increasing Hospitalization Rates for Cirrhosis: Overrepresentation of Disadvantaged Australians.

Powell EE, Skoien R, Rahman T, Clark PJ, O'Beirne J, Hartel G, Stuart KA, McPhail SM, Gupta R, Boyd P, Valery PC.

EClinicalMedicine. 2019 Jun 13;11:44-53. doi: 10.1016/j.eclinm.2019.05.007. eCollection 2019 May-Jun.


Effects of Antibiotic Therapy in Primary Sclerosing Cholangitis with and without Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

Shah A, Crawford D, Burger D, Martin N, Walker M, Talley NJ, Tallis C, Jones M, Stuart K, Keely S, Lewindon P, Macdonald GA, Morrison M, Holtmann GJ.

Semin Liver Dis. 2019 Nov;39(4):432-441. doi: 10.1055/s-0039-1688501. Epub 2019 Jul 17.


Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in Trypanosoma brucei.

McDermott SM, Carnes J, Stuart K.

RNA. 2019 Sep;25(9):1150-1163. doi: 10.1261/rna.071258.119. Epub 2019 Jun 6.


Medication-Related Problems in Outpatients With Decompensated Cirrhosis: Opportunities for Harm Prevention.

Hayward KL, Patel PJ, Valery PC, Horsfall LU, Li CY, Wright PL, Tallis CJ, Stuart KA, Irvine KM, Cottrell WN, Martin JH, Powell EE.

Hepatol Commun. 2019 Mar 18;3(5):620-631. doi: 10.1002/hep4.1334. eCollection 2019 May.


Late-life environmental enrichment preserves short-term memory and may attenuate microglia in male APP/PS1 mice.

Stuart KE, King AE, King NE, Collins JM, Vickers JC, Ziebell JM.

Neuroscience. 2019 Jun 1;408:282-292. doi: 10.1016/j.neuroscience.2019.04.015. Epub 2019 Apr 16.


Beneficial response to mycophenolate mofetil by patients with autoimmune hepatitis who have failed standard therapy, is predicted by older age and lower immunoglobulin G and INR levels.

Nicoll AJ, Roberts SK, Lim R, Mitchell J, Weltman M, George J, Wigg A, Stuart K, Gow P, MacQuillan G, Tse E, Levy M, Sood S, Zekry A, Cheng W, Mitchell J, Skoien R, Sievert W, Strasser SI, McCaughan GW; ALA Clinical Research Network, Gastroenterological Society of Australia.

Aliment Pharmacol Ther. 2019 May;49(10):1314-1322. doi: 10.1111/apt.15248. Epub 2019 Apr 11.


Location of arm draining lymph node in relation to breast cancer radiotherapy field and target volume.

Wang W, Ward R, Jia D, Ashworth S, Estoesta E, Moodie T, Ahern V, Stuart K, Ngui N, French J, Elder E, Farlow D.

Radiother Oncol. 2019 Apr;133:193-197. doi: 10.1016/j.radonc.2018.10.038. Epub 2018 Nov 13.


Nuclear Phosphatidylinositol 5-Phosphatase Is Essential for Allelic Exclusion of Variant Surface Glycoprotein Genes in Trypanosomes.

Cestari I, McLeland-Wieser H, Stuart K.

Mol Cell Biol. 2019 Jan 16;39(3). pii: e00395-18. doi: 10.1128/MCB.00395-18. Print 2019 Feb 1.


Contouring consensus guidelines in breast cancer radiotherapy: Comparison and systematic review of patterns of failure.

Gee HE, Moses L, Stuart K, Nahar N, Tiver K, Wang T, Ward R, Ahern V.

J Med Imaging Radiat Oncol. 2019 Feb;63(1):102-115. doi: 10.1111/1754-9485.12804. Epub 2018 Sep 29.


A Pragmatic Approach Identifies a High Rate of Nonalcoholic Fatty Liver Disease With Advanced Fibrosis in Diabetes Clinics and At-Risk Populations in Primary Care.

Patel P, Hossain F, Horsfall LU, Banh X, Hayward KL, Williams S, Johnson T, Bernard A, Brown NN, Lampe G, Buck L, Saad N, Russell AW, Valery PC, Irvine KM, Clouston AD, Stuart KA, Rosenberg W, Powell EE.

Hepatol Commun. 2018 Aug 6;2(8):893-905. doi: 10.1002/hep4.1208. eCollection 2018 Aug.


Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period.

Rothen J, Murie C, Carnes J, Anupama A, Abdulla S, Chemba M, Mpina M, Tanner M, Lee Sim BK, Hoffman SL, Gottardo R, Daubenberger C, Stuart K.

PLoS One. 2018 Jun 19;13(6):e0199392. doi: 10.1371/journal.pone.0199392. eCollection 2018.


Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease.

Britton L, Bridle K, Reiling J, Santrampurwala N, Wockner L, Ching H, Stuart K, Subramaniam VN, Jeffrey G, St Pierre T, House M, Gummer J, Trengove R, Olynyk J, Crawford D, Adams L.

Hepatol Commun. 2018 Apr 27;2(6):644-653. doi: 10.1002/hep4.1190. eCollection 2018 Jun.


Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control.

Patel PJ, Hossain F, Horsfall LU, Banh X, Hayward KL, Williams S, Johnson T, Brown NN, Saad N, Valery PC, Irvine KM, Clouston AD, Stuart KA, Russell AW, Powell EE.

J Diabetes Complications. 2018 Aug;32(8):799-804. doi: 10.1016/j.jdiacomp.2018.05.008. Epub 2018 May 12.


The BDNF Val66Met polymorphism moderates the relationship between Posttraumatic Stress Disorder and fear extinction learning.

Felmingham KL, Zuj DV, Hsu KCM, Nicholson E, Palmer MA, Stuart K, Vickers JC, Malhi GS, Bryant RA.

Psychoneuroendocrinology. 2018 May;91:142-148. doi: 10.1016/j.psyneuen.2018.03.002. Epub 2018 Mar 6.


Patient education using virtual reality increases knowledge and positive experience for breast cancer patients undergoing radiation therapy.

Jimenez YA, Cumming S, Wang W, Stuart K, Thwaites DI, Lewis SJ.

Support Care Cancer. 2018 Aug;26(8):2879-2888. doi: 10.1007/s00520-018-4114-4. Epub 2018 Mar 13.


Inositol polyphosphate multikinase regulation of Trypanosoma brucei life stage development.

Cestari I, Anupama A, Stuart K.

Mol Biol Cell. 2018 May 1;29(9):1137-1152. doi: 10.1091/mbc.E17-08-0515. Epub 2018 Mar 22.


Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes.

Cestari I, Stuart K.

Curr Genomics. 2018 Feb;19(2):119-132. doi: 10.2174/1389202918666170911161831. Review.


RNase III Domain of KREPB9 and KREPB10 Association with Editosomes in Trypanosoma brucei.

Carnes J, McDermott SM, Stuart K.

mSphere. 2018 Jan 17;3(1). pii: e00585-17. doi: 10.1128/mSphereDirect.00585-17. eCollection 2018 Jan-Feb.


Capecitabine and oxaliplatin as first and second line treatment for locally advanced and metastatic pancreatic ductal adenocarcinoma.

Bullock A, Stuart K, Jacobus S, Abrams T, Wadlow R, Goldstein M, Miksad R.

J Gastrointest Oncol. 2017 Dec;8(6):945-952. doi: 10.21037/jgo.2017.06.06.


Developing a Newborn Resuscitation Telemedicine Program: A Comparison of Two Technologies.

Beck JA, Jensen JA, Putzier RF, Stubert LA, Stuart KD, Mohammed H, Kreofsky BL, Boles KW, Colby CE, Fang JL.

Telemed J E Health. 2018 Jul;24(7):481-488. doi: 10.1089/tmj.2017.0121. Epub 2017 Dec 12.


Alcohol Consumption in Diabetic Patients with Nonalcoholic Fatty Liver Disease.

Patel PJ, Smith D, Connor JP, Horsfall LU, Hayward KL, Hossain F, Williams S, Johnson T, Stuart KA, Brown NN, Saad N, Clouston AD, Irvine KM, Russell AW, Valery PC, Powell EE.

Can J Gastroenterol Hepatol. 2017;2017:7927685. doi: 10.1155/2017/7927685. Epub 2017 Nov 1.


Comparative Proteomic Analysis of Lysine Acetylation in Trypanosomes.

Moretti NS, Cestari I, Anupama A, Stuart K, Schenkman S.

J Proteome Res. 2018 Jan 5;17(1):374-385. doi: 10.1021/acs.jproteome.7b00603. Epub 2017 Dec 11.


Medication beliefs predict medication adherence in ambulatory patients with decompensated cirrhosis.

Hayward KL, Valery PC, Martin JH, Karmakar A, Patel PJ, Horsfall LU, Tallis CJ, Stuart KA, Wright PL, Smith DD, Irvine KM, Powell EE, Cottrell WN.

World J Gastroenterol. 2017 Oct 28;23(40):7321-7331. doi: 10.3748/wjg.v23.i40.7321.


Age is no barrier: predictors of academic success in older learners.

Imlach AR, Ward DD, Stuart KE, Summers MJ, Valenzuela MJ, King AE, Saunders NL, Summers J, Srikanth VK, Robinson A, Vickers JC.

NPJ Sci Learn. 2017 Nov 15;2:13. doi: 10.1038/s41539-017-0014-5. eCollection 2017.


In Reply to Drs Lipman and Hackett.

Kanaan NC, Peterson AL, Pun M, Thapa GB, Tiwari A, Basyal B, Holck PS, Starling J, Freeman TF, Gehner JR, Keyes L, Levin DR, O'Leary CJ, Stuart KE, Velgersdyk JL, Zafren K, Basnyat B.

Wilderness Environ Med. 2017 Dec;28(4):385-387. doi: 10.1016/j.wem.2017.09.005. Epub 2017 Oct 28. No abstract available.


Underappreciation of non-alcoholic fatty liver disease by primary care clinicians: limited awareness of surrogate markers of fibrosis.

Patel PJ, Banh X, Horsfall LU, Hayward KL, Hossain F, Johnson T, Stuart KA, Brown NN, Saad N, Clouston A, Irvine KM, Russell AW, Valery PC, Williams S, Powell EE.

Intern Med J. 2018 Feb;48(2):144-151. doi: 10.1111/imj.13667.


Efficacy and Safety of Mycophenolate Mofetil in Patients With Autoimmune Hepatitis and Suboptimal Outcomes After Standard Therapy.

Roberts SK, Lim R, Strasser S, Nicoll A, Gazzola A, Mitchell J, Siow W, Khoo T, Hamarneh Z, Weltman M, Gow P, Janko N, Tse E, Mishra G, Cheng EH, Levy M, Cheng W, Sood S, Skoien R, Mitchell J, Zekry A, George J, MacQuillan G, Wigg A, Stuart K, Sievert W, McCaughan G; ALA Clinical Research Network.

Clin Gastroenterol Hepatol. 2018 Feb;16(2):268-277. doi: 10.1016/j.cgh.2017.09.063. Epub 2017 Oct 16.


The essential functions of KREPB4 are developmentally distinct and required for endonuclease association with editosomes.

McDermott SM, Stuart K.

RNA. 2017 Nov;23(11):1672-1684. doi: 10.1261/rna.062786.117. Epub 2017 Aug 11.


Multimorbidity and polypharmacy in diabetic patients with NAFLD: Implications for disease severity and management.

Patel PJ, Hayward KL, Rudra R, Horsfall LU, Hossain F, Williams S, Johnson T, Brown NN, Saad N, Clouston AD, Stuart KA, Valery PC, Irvine KM, Russell AW, Powell EE.

Medicine (Baltimore). 2017 Jun;96(26):e6761. doi: 10.1097/MD.0000000000006761.


Predicting inpatient hypoglycaemia in hospitalized patients with diabetes: a retrospective analysis of 9584 admissions with diabetes.

Stuart K, Adderley NJ, Marshall T, Rayman G, Sitch A, Manley S, Ghosh S, Toulis KA, Nirantharakumar K.

Diabet Med. 2017 Oct;34(10):1385-1391. doi: 10.1111/dme.13409. Epub 2017 Jul 12.


Environmental novelty exacerbates stress hormones and Aβ pathology in an Alzheimer's model.

Stuart KE, King AE, Fernandez-Martos CM, Summers MJ, Vickers JC.

Sci Rep. 2017 Jun 5;7(1):2764. doi: 10.1038/s41598-017-03016-0.


Controlled Human Malaria Infection Leads to Long-Lasting Changes in Innate and Innate-like Lymphocyte Populations.

Mpina M, Maurice NJ, Yajima M, Slichter CK, Miller HW, Dutta M, McElrath MJ, Stuart KD, De Rosa SC, McNevin JP, Linsley PS, Abdulla S, Tanner M, Hoffman SL, Gottardo R, Daubenberger CA, Prlic M.

J Immunol. 2017 Jul 1;199(1):107-118. doi: 10.4049/jimmunol.1601989. Epub 2017 Jun 2.


Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling.

Cook SJ, Stuart K, Gilley R, Sale MJ.

FEBS J. 2017 Dec;284(24):4177-4195. doi: 10.1111/febs.14122. Epub 2017 Jun 18. Review.


Prophylactic Acetaminophen or Ibuprofen Results in Equivalent Acute Mountain Sickness Incidence at High Altitude: A Prospective Randomized Trial.

Kanaan NC, Peterson AL, Pun M, Holck PS, Starling J, Basyal B, Freeman TF, Gehner JR, Keyes L, Levin DR, O'Leary CJ, Stuart KE, Thapa GB, Tiwari A, Velgersdyk JL, Zafren K, Basnyat B.

Wilderness Environ Med. 2017 Jun;28(2):72-78. doi: 10.1016/j.wem.2016.12.011. Epub 2017 May 4. Erratum in: Wilderness Environ Med. 2017 Sep;28(3):281.


Real-world efficacy and safety of ritonavir-boosted paritaprevir, ombitasvir, dasabuvir ± ribavirin for hepatitis C genotype 1 - final results of the REV1TAL study.

Lubel J, Strasser S, Stuart KA, Dore G, Thompson A, Pianko S, Bollipo S, Mitchell JL, Fragomeli V, Jones T, Chivers S, Gow P, Iser D, Levy M, Tse E, Gazzola A, Cheng W, Nazareth S, Galhenage S, Wade A, Weltman M, Wigg A, MacQuillan G, Sasadeusz J, George J, Zekry A, Roberts SK; Australian Liver Association Clinical Research Network (ALA CRN).

Antivir Ther. 2017;22(8):699-710. doi: 10.3851/IMP3168.


In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases.

Carnes J, McDermott S, Anupama A, Oliver BG, Sather DN, Stuart K.

Nucleic Acids Res. 2017 May 5;45(8):4667-4686. doi: 10.1093/nar/gkx116.


Breast Cancer Patients' Perceptions of a Virtual Learning Environment for Pretreatment Education.

Jimenez YA, Wang W, Stuart K, Cumming S, Thwaites D, Lewis S.

J Cancer Educ. 2018 Oct;33(5):983-990. doi: 10.1007/s13187-017-1183-x.


Whole breast hypofractionation: Trials, guidelines and clinical practice.

Conroy R, Gebski V, Latty D, Wang T, Stuart K, Ahern V.

J Med Imaging Radiat Oncol. 2017 Feb;61(1):157-158. doi: 10.1111/1754-9485.12574. No abstract available.


Mid-life environmental enrichment increases synaptic density in CA1 in a mouse model of Aβ-associated pathology and positively influences synaptic and cognitive health in healthy ageing.

Stuart KE, King AE, Fernandez-Martos CM, Dittmann J, Summers MJ, Vickers JC.

J Comp Neurol. 2017 Jun 1;525(8):1797-1810. doi: 10.1002/cne.24156. Epub 2017 Mar 14.


The Architecture of Trypanosoma brucei editosomes.

McDermott SM, Luo J, Carnes J, Ranish JA, Stuart K.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6476-E6485. Epub 2016 Oct 5.


Chemogenetic Characterization of Inositol Phosphate Metabolic Pathway Reveals Druggable Enzymes for Targeting Kinetoplastid Parasites.

Cestari I, Haas P, Moretti NS, Schenkman S, Stuart K.

Cell Chem Biol. 2016 May 19;23(5):608-617. doi: 10.1016/j.chembiol.2016.03.015. Epub 2016 Apr 28.


Left-sided breast cancer loco-regional radiotherapy with deep inspiration breath-hold: Does volumetric-modulated arc radiotherapy reduce heart dose further compared with tangential intensity-modulated radiotherapy?

Pham TT, Ward R, Latty D, Owen C, Gebski V, Chojnowski J, Kelly C, Ahern V, Tiver K, Stuart K, Wang W.

J Med Imaging Radiat Oncol. 2016 Aug;60(4):545-53. doi: 10.1111/1754-9485.12459. Epub 2016 Apr 20.


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