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Items: 1 to 50 of 166

1.

Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Davies MR, McIntyre L, Mutreja A, Lacey JA, Lees JA, Towers RJ, Duchêne S, Smeesters PR, Frost HR, Price DJ, Holden MTG, David S, Giffard PM, Worthing KA, Seale AC, Berkley JA, Harris SR, Rivera-Hernandez T, Berking O, Cork AJ, Torres RSLA, Lithgow T, Strugnell RA, Bergmann R, Nitsche-Schmitz P, Chhatwal GS, Bentley SD, Fraser JD, Moreland NJ, Carapetis JR, Steer AC, Parkhill J, Saul A, Williamson DA, Currie BJ, Tong SYC, Dougan G, Walker MJ.

Nat Genet. 2019 Aug;51(8):1295. doi: 10.1038/s41588-019-0482-z.

PMID:
31324894
2.

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Davies MR, McIntyre L, Mutreja A, Lacey JA, Lees JA, Towers RJ, Duchêne S, Smeesters PR, Frost HR, Price DJ, Holden MTG, David S, Giffard PM, Worthing KA, Seale AC, Berkley JA, Harris SR, Rivera-Hernandez T, Berking O, Cork AJ, Torres RSLA, Lithgow T, Strugnell RA, Bergmann R, Nitsche-Schmitz P, Chhatwal GS, Bentley SD, Fraser JD, Moreland NJ, Carapetis JR, Steer AC, Parkhill J, Saul A, Williamson DA, Currie BJ, Tong SYC, Dougan G, Walker MJ.

Nat Genet. 2019 Jun;51(6):1035-1043. doi: 10.1038/s41588-019-0417-8. Epub 2019 May 27. Erratum in: Nat Genet. 2019 Jul 19;:.

PMID:
31133745
3.

Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome.

Simpfendorfer KR, Wang N, Tull DL, De Souza DP, Nahid A, Mu A, Hocking DM, Pedersen JS, Wijburg OLC, McConville MJ, Strugnell RA.

Mol Med. 2019 Apr 3;25(1):12. doi: 10.1186/s10020-019-0077-2.

4.

Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways.

Newson JPM, Scott NE, Yeuk Wah Chung I, Wong Fok Lung T, Giogha C, Gan J, Wang N, Strugnell RA, Brown NF, Cygler M, Pearson JS, Hartland EL.

Mol Cell Proteomics. 2019 Jun;18(6):1138-1156. doi: 10.1074/mcp.RA118.001093. Epub 2019 Mar 22.

PMID:
30902834
5.

Resistance mechanisms and population structure of highly drug resistant Klebsiella in Pakistan during the introduction of the carbapenemase NDM-1.

Heinz E, Ejaz H, Bartholdson Scott J, Wang N, Gujaran S, Pickard D, Wilksch J, Cao H, Haq IU, Dougan G, Strugnell RA.

Sci Rep. 2019 Feb 20;9(1):2392. doi: 10.1038/s41598-019-38943-7.

6.

Optimal protection against Salmonella infection requires noncirculating memory.

Benoun JM, Peres NG, Wang N, Pham OH, Rudisill VL, Fogassy ZN, Whitney PG, Fernandez-Ruiz D, Gebhardt T, Pham QM, Puddington L, Bedoui S, Strugnell RA, McSorley SJ.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10416-10421. doi: 10.1073/pnas.1808339115. Epub 2018 Sep 25.

7.

MAIT cells protect against pulmonary Legionella longbeachae infection.

Wang H, D'Souza C, Lim XY, Kostenko L, Pediongco TJ, Eckle SBG, Meehan BS, Shi M, Wang N, Li S, Liu L, Mak JYW, Fairlie DP, Iwakura Y, Gunnersen JM, Stent AW, Godfrey DI, Rossjohn J, Westall GP, Kjer-Nielsen L, Strugnell RA, McCluskey J, Corbett AJ, Hinks TSC, Chen Z.

Nat Commun. 2018 Aug 22;9(1):3350. doi: 10.1038/s41467-018-05202-8.

8.

FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants.

Grinter R, Hay ID, Song J, Wang J, Teng D, Dhanesakaran V, Wilksch JJ, Davies MR, Littler D, Beckham SA, Henderson IR, Strugnell RA, Dougan G, Lithgow T.

PLoS Biol. 2018 Aug 2;16(8):e2006026. doi: 10.1371/journal.pbio.2006026. eCollection 2018 Aug.

9.

Epidemiology and risk factors for typhoid fever in Central Division, Fiji, 2014-2017: A case-control study.

Prasad N, Jenkins AP, Naucukidi L, Rosa V, Sahu-Khan A, Kama M, Jenkins KM, Jenney AWJ, Jack SJ, Saha D, Horwitz P, Jupiter SD, Strugnell RA, Mulholland EK, Crump JA.

PLoS Negl Trop Dis. 2018 Jun 8;12(6):e0006571. doi: 10.1371/journal.pntd.0006571. eCollection 2018 Jun.

10.

An investigation into the Omp85 protein BamK in hypervirulent Klebsiella pneumoniae, and its role in outer membrane biogenesis.

Torres VVL, Heinz E, Stubenrauch CJ, Wilksch JJ, Cao H, Yang J, Clements A, Dunstan RA, Alcock F, Webb CT, Dougan G, Strugnell RA, Hay ID, Lithgow T.

Mol Microbiol. 2018 Sep;109(5):584-599. doi: 10.1111/mmi.13990. Epub 2018 Sep 19.

PMID:
29873128
11.

The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane.

Gunasinghe SD, Shiota T, Stubenrauch CJ, Schulze KE, Webb CT, Fulcher AJ, Dunstan RA, Hay ID, Naderer T, Whelan DR, Bell TDM, Elgass KD, Strugnell RA, Lithgow T.

Cell Rep. 2018 May 29;23(9):2782-2794. doi: 10.1016/j.celrep.2018.04.093.

12.

Methionine biosynthesis and transport are functionally redundant for the growth and virulence of Salmonella Typhimurium.

Husna AU, Wang N, Cobbold SA, Newton HJ, Hocking DM, Wilksch JJ, Scott TA, Davies MR, Hinton JC, Tree JJ, Lithgow T, McConville MJ, Strugnell RA.

J Biol Chem. 2018 Jun 15;293(24):9506-9519. doi: 10.1074/jbc.RA118.002592. Epub 2018 May 2.

13.

Bastion6: a bioinformatics approach for accurate prediction of type VI secreted effectors.

Wang J, Yang B, Leier A, Marquez-Lago TT, Hayashida M, Rocker A, Zhang Y, Akutsu T, Chou KC, Strugnell RA, Song J, Lithgow T.

Bioinformatics. 2018 Aug 1;34(15):2546-2555. doi: 10.1093/bioinformatics/bty155.

14.

Fitness cost of mcr-1-mediated polymyxin resistance in Klebsiella pneumoniae.

Nang SC, Morris FC, McDonald MJ, Han ML, Wang J, Strugnell RA, Velkov T, Li J.

J Antimicrob Chemother. 2018 Jun 1;73(6):1604-1610. doi: 10.1093/jac/dky061.

PMID:
29514208
15.

Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection.

D'Souza C, Pediongco T, Wang H, Scheerlinck JY, Kostenko L, Esterbauer R, Stent AW, Eckle SBG, Meehan BS, Strugnell RA, Cao H, Liu L, Mak JYW, Lovrecz G, Lu L, Fairlie DP, Rossjohn J, McCluskey J, Every AL, Chen Z, Corbett AJ.

J Immunol. 2018 Mar 1;200(5):1901-1916. doi: 10.4049/jimmunol.1701512. Epub 2018 Jan 29.

16.

Antimicrobial-Resistant Klebsiella pneumoniae Carriage and Infection in Specialized Geriatric Care Wards Linked to Acquisition in the Referring Hospital.

Gorrie CL, Mirceta M, Wick RR, Judd LM, Wyres KL, Thomson NR, Strugnell RA, Pratt NF, Garlick JS, Watson KM, Hunter PC, McGloughlin SA, Spelman DW, Jenney AWJ, Holt KE.

Clin Infect Dis. 2018 Jul 2;67(2):161-170. doi: 10.1093/cid/ciy027.

17.

Corrigendum: Successful treatment of biofilm infections using shock waves combined with antibiotic therapy.

Gnanadhas DP, Elango M, Janardhanraj S, Srinandan CS, Datey A, Strugnell RA, Gopalan J, Chakravortty D.

Sci Rep. 2018 Jan 8;8:46929. doi: 10.1038/srep46929.

18.

Systematic analysis and prediction of type IV secreted effector proteins by machine learning approaches.

Wang J, Yang B, An Y, Marquez-Lago T, Leier A, Wilksch J, Hong Q, Zhang Y, Hayashida M, Akutsu T, Webb GI, Strugnell RA, Song J, Lithgow T.

Brief Bioinform. 2019 May 21;20(3):931-951. doi: 10.1093/bib/bbx164.

19.

Reductive evolution in outer membrane protein biogenesis has not compromised cell surface complexity in Helicobacter pylori.

Webb CT, Chandrapala D, Oslan SN, Bamert RS, Grinter RD, Dunstan RA, Gorrell RJ, Song J, Strugnell RA, Lithgow T, Kwok T.

Microbiologyopen. 2017 Dec;6(6). doi: 10.1002/mbo3.513. Epub 2017 Oct 21.

20.

Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan.

Ejaz H, Wang N, Wilksch JJ, Page AJ, Cao H, Gujaran S, Keane JA, Lithgow T, Ul-Haq I, Dougan G, Strugnell RA, Heinz E.

Emerg Infect Dis. 2017 Nov;23(11):1872-1875. doi: 10.3201/eid2311.170833.

21.

Extensively Drug-Resistant Klebsiella pneumoniae Causing Nosocomial Bloodstream Infections in China: Molecular Investigation of Antibiotic Resistance Determinants, Informing Therapy, and Clinical Outcomes.

Bi W, Liu H, Dunstan RA, Li B, Torres VVL, Cao J, Chen L, Wilksch JJ, Strugnell RA, Lithgow T, Zhou T.

Front Microbiol. 2017 Jun 30;8:1230. doi: 10.3389/fmicb.2017.01230. eCollection 2017.

22.

Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients.

Gorrie CL, Mirceta M, Wick RR, Edwards DJ, Thomson NR, Strugnell RA, Pratt NF, Garlick JS, Watson KM, Pilcher DV, McGloughlin SA, Spelman DW, Jenney AWJ, Holt KE.

Clin Infect Dis. 2017 Jul 15;65(2):208-215. doi: 10.1093/cid/cix270.

23.

Influence of Fimbriae on Bacterial Adhesion and Viscoelasticity and Correlations of the Two Properties with Biofilm Formation.

Wang H, Wilksch JJ, Chen L, Tan JW, Strugnell RA, Gee ML.

Langmuir. 2017 Jan 10;33(1):100-106. doi: 10.1021/acs.langmuir.6b03764. Epub 2016 Dec 21.

PMID:
27959542
24.

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine.

Stubenrauch C, Belousoff MJ, Hay ID, Shen HH, Lillington J, Tuck KL, Peters KM, Phan MD, Lo AW, Schembri MA, Strugnell RA, Waksman G, Lithgow T.

Nat Microbiol. 2016 May 16;1(7):16064. doi: 10.1038/nmicrobiol.2016.64.

PMID:
27572967
25.

Correction to "Atomic Force Microscopy Reveals the Mechanobiology of Lytic Peptide Action on Bacteria".

Mularski A, Wilksch JJ, Wang H, Hossain MA, Wade JD, Separovic F, Strugnell RA, Gee ML.

Langmuir. 2016 Jun 14;32(23):6010. doi: 10.1021/acs.langmuir.6b01939. Epub 2016 Jun 6. No abstract available.

PMID:
27263366
26.

Conserved Features in the Structure, Mechanism, and Biogenesis of the Inverse Autotransporter Protein Family.

Heinz E, Stubenrauch CJ, Grinter R, Croft NP, Purcell AW, Strugnell RA, Dougan G, Lithgow T.

Genome Biol Evol. 2016 Jun 13;8(6):1690-705. doi: 10.1093/gbe/evw112.

27.

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.

Chen Z, Wang H, D'Souza C, Sun S, Kostenko L, Eckle SB, Meehan BS, Jackson DC, Strugnell RA, Cao H, Wang N, Fairlie DP, Liu L, Godfrey DI, Rossjohn J, McCluskey J, Corbett AJ.

Mucosal Immunol. 2017 Jan;10(1):58-68. doi: 10.1038/mi.2016.39. Epub 2016 May 4.

PMID:
27143301
28.

The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1.

McWilliam HE, Eckle SB, Theodossis A, Liu L, Chen Z, Wubben JM, Fairlie DP, Strugnell RA, Mintern JD, McCluskey J, Rossjohn J, Villadangos JA.

Nat Immunol. 2016 May;17(5):531-7. doi: 10.1038/ni.3416. Epub 2016 Apr 4.

PMID:
27043408
29.

Atomic force microscopy of bacteria reveals the mechanobiology of pore forming peptide action.

Mularski A, Wilksch JJ, Hanssen E, Strugnell RA, Separovic F.

Biochim Biophys Acta. 2016 Jun;1858(6):1091-8. doi: 10.1016/j.bbamem.2016.03.002. Epub 2016 Mar 4.

30.

Heat shock protein complex vaccines induce antibodies against Neisseria meningitidis via a MyD88-independent mechanism.

Han JX, Ng GZ, Cecchini P, Chionh YT, Saeed MA, Næss LM, Joachim M, Blandford LE, Strugnell RA, Colaco CA, Sutton P.

Vaccine. 2016 Mar 29;34(14):1704-11. doi: 10.1016/j.vaccine.2016.02.001. Epub 2016 Feb 12.

PMID:
26876441
31.

Molecular Characterization of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli.

Nichols KB, Totsika M, Moriel DG, Lo AW, Yang J, Wurpel DJ, Rossiter AE, Strugnell RA, Henderson IR, Ulett GC, Beatson SA, Schembri MA.

J Bacteriol. 2016 Apr 28;198(10):1487-98. doi: 10.1128/JB.00791-15. Print 2016 May 15.

32.

T Cell Help Amplifies Innate Signals in CD8(+) DCs for Optimal CD8(+) T Cell Priming.

Greyer M, Whitney PG, Stock AT, Davey GM, Tebartz C, Bachem A, Mintern JD, Strugnell RA, Turner SJ, Gebhardt T, O'Keeffe M, Heath WR, Bedoui S.

Cell Rep. 2016 Jan 26;14(3):586-597. doi: 10.1016/j.celrep.2015.12.058. Epub 2016 Jan 7.

33.

Successful treatment of biofilm infections using shock waves combined with antibiotic therapy.

Gnanadhas DP, Elango M, Janardhanraj S, Srinandan CS, Datey A, Strugnell RA, Gopalan J, Chakravortty D.

Sci Rep. 2015 Dec 10;5:17440. doi: 10.1038/srep17440. Erratum in: Sci Rep. 2018 Jan 08;8:46929.

34.

Vaccination Method Affects Immune Response and Bacterial Growth but Not Protection in the Salmonella Typhimurium Animal Model of Typhoid.

Kinnear CL, Strugnell RA.

PLoS One. 2015 Oct 28;10(10):e0141356. doi: 10.1371/journal.pone.0141356. eCollection 2015.

35.

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module.

Selkrig J, Belousoff MJ, Headey SJ, Heinz E, Shiota T, Shen HH, Beckham SA, Bamert RS, Phan MD, Schembri MA, Wilce MC, Scanlon MJ, Strugnell RA, Lithgow T.

Sci Rep. 2015 Aug 5;5:12905. doi: 10.1038/srep12905.

36.

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health.

Holt KE, Wertheim H, Zadoks RN, Baker S, Whitehouse CA, Dance D, Jenney A, Connor TR, Hsu LY, Severin J, Brisse S, Cao H, Wilksch J, Gorrie C, Schultz MB, Edwards DJ, Nguyen KV, Nguyen TV, Dao TT, Mensink M, Minh VL, Nhu NT, Schultsz C, Kuntaman K, Newton PN, Moore CE, Strugnell RA, Thomson NR.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3574-81. doi: 10.1073/pnas.1501049112. Epub 2015 Jun 22.

37.

Role of Capsular Polysaccharides in Biofilm Formation: An AFM Nanomechanics Study.

Wang H, Wilksch JJ, Strugnell RA, Gee ML.

ACS Appl Mater Interfaces. 2015 Jun 17;7(23):13007-13. doi: 10.1021/acsami.5b03041. Epub 2015 Jun 2.

PMID:
26034816
38.

Atomic Force Microscopy Reveals the Mechanobiology of Lytic Peptide Action on Bacteria.

Mularski A, Wilksch JJ, Wang H, Hossain MA, Wade JD, Separovic F, Strugnell RA, Gee ML.

Langmuir. 2015 Jun 9;31(22):6164-71. doi: 10.1021/acs.langmuir.5b01011. Epub 2015 May 26. Erratum in: Langmuir. 2016 Jun 14;32(23):6010.

PMID:
25978768
39.

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA.

Dunstan RA, Hay ID, Wilksch JJ, Schittenhelm RB, Purcell AW, Clark J, Costin A, Ramm G, Strugnell RA, Lithgow T.

Mol Microbiol. 2015 Aug;97(4):616-29. doi: 10.1111/mmi.13055. Epub 2015 Jun 6.

40.

Increased autoimmune diabetes in pIgR-deficient NOD mice is due to a "Hitchhiking" interval that refines the genetic effect of Idd5.4.

Simpfendorfer KR, Strugnell RA, Brodnicki TC, Wijburg OL.

PLoS One. 2015 Apr 2;10(4):e0121979. doi: 10.1371/journal.pone.0121979. eCollection 2015.

41.

Positive autoregulation of mrkHI by the cyclic di-GMP-dependent MrkH protein in the biofilm regulatory circuit of Klebsiella pneumoniae.

Tan JW, Wilksch JJ, Hocking DM, Wang N, Srikhanta YN, Tauschek M, Lithgow T, Robins-Browne RM, Yang J, Strugnell RA.

J Bacteriol. 2015 May;197(9):1659-67. doi: 10.1128/JB.02615-14. Epub 2015 Mar 2.

42.

Cellular requirements for systemic control of Salmonella enterica serovar Typhimurium infections in mice.

Kupz A, Bedoui S, Strugnell RA.

Infect Immun. 2014 Dec;82(12):4997-5004. doi: 10.1128/IAI.02192-14. Epub 2014 Sep 15.

43.

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes.

Leyton DL, Johnson MD, Thapa R, Huysmans GH, Dunstan RA, Celik N, Shen HH, Loo D, Belousoff MJ, Purcell AW, Henderson IR, Beddoe T, Rossjohn J, Martin LL, Strugnell RA, Lithgow T.

Nat Commun. 2014 Jun 26;5:4239. doi: 10.1038/ncomms5239.

PMID:
24967730
44.

Analysis of Salmonella enterica serovar Typhimurium variable-number tandem-repeat data for public health investigation based on measured mutation rates and whole-genome sequence comparisons.

Dimovski K, Cao H, Wijburg OL, Strugnell RA, Mantena RK, Whipp M, Hogg G, Holt KE.

J Bacteriol. 2014 Aug 15;196(16):3036-44. doi: 10.1128/JB.01820-14. Epub 2014 Jun 23.

45.

Congenic mice reveal genetic epistasis and overlapping disease loci for autoimmune diabetes and listeriosis.

Wang N, Elso CM, Mackin L, Mannering SI, Strugnell RA, Wijburg OL, Brodnicki TC.

Immunogenetics. 2014 Aug;66(7-8):501-6. doi: 10.1007/s00251-014-0782-5. Epub 2014 Jun 7.

PMID:
24906421
46.

In vivo IFN-γ secretion by NK cells in response to Salmonella typhimurium requires NLRC4 inflammasomes.

Kupz A, Curtiss R 3rd, Bedoui S, Strugnell RA.

PLoS One. 2014 May 14;9(5):e97418. doi: 10.1371/journal.pone.0097418. eCollection 2014.

47.

T-cell activation by transitory neo-antigens derived from distinct microbial pathways.

Corbett AJ, Eckle SB, Birkinshaw RW, Liu L, Patel O, Mahony J, Chen Z, Reantragoon R, Meehan B, Cao H, Williamson NA, Strugnell RA, Van Sinderen D, Mak JY, Fairlie DP, Kjer-Nielsen L, Rossjohn J, McCluskey J.

Nature. 2014 May 15;509(7500):361-5. doi: 10.1038/nature13160. Epub 2014 Apr 2.

PMID:
24695216
48.

F9 fimbriae of uropathogenic Escherichia coli are expressed at low temperature and recognise Galβ1-3GlcNAc-containing glycans.

Wurpel DJ, Totsika M, Allsopp LP, Hartley-Tassell LE, Day CJ, Peters KM, Sarkar S, Ulett GC, Yang J, Tiralongo J, Strugnell RA, Jennings MP, Schembri MA.

PLoS One. 2014 Mar 26;9(3):e93177. doi: 10.1371/journal.pone.0093177. eCollection 2014.

49.

Salmonella vaccines: lessons from the mouse model or bad teaching?

Strugnell RA, Scott TA, Wang N, Yang C, Peres N, Bedoui S, Kupz A.

Curr Opin Microbiol. 2014 Feb;17:99-105. doi: 10.1016/j.mib.2013.12.004. Epub 2014 Jan 20. Review.

PMID:
24440968
50.

Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein.

Yang J, Wilksch JJ, Tan JW, Hocking DM, Webb CT, Lithgow T, Robins-Browne RM, Strugnell RA.

PLoS One. 2013 Nov 14;8(11):e79038. doi: 10.1371/journal.pone.0079038. eCollection 2013.

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