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Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus.

Colley T, Sharma C, Alanio A, Kimura G, Daly L, Nakaoki T, Nishimoto Y, Bretagne S, Kizawa Y, Strong P, Rapeport G, Ito K, Meis JF, Chowdhary A.

J Antimicrob Chemother. 2019 Oct 1;74(10):2950-2958. doi: 10.1093/jac/dkz302.


In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris.

Rudramurthy SM, Colley T, Abdolrasouli A, Ashman J, Dhaliwal M, Kaur H, Armstrong-James D, Strong P, Rapeport G, Schelenz S, Ito K, Chakrabarti A.

J Antimicrob Chemother. 2019 Oct 1;74(10):2943-2949. doi: 10.1093/jac/dkz280.


Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection.

Colley T, Sehra G, Daly L, Kimura G, Nakaoki T, Nishimoto Y, Kizawa Y, Strong P, Rapeport G, Ito K.

Sci Rep. 2019 Jul 1;9(1):9482. doi: 10.1038/s41598-019-45890-w.


Carbon nanotube-grafted chitosan and its adsorption capacity for phenol in aqueous solution.

Guo M, Wang J, Wang C, Strong PJ, Jiang P, Ok YS, Wang H.

Sci Total Environ. 2019 Sep 10;682:340-347. doi: 10.1016/j.scitotenv.2019.05.148. Epub 2019 May 15.


Friends or Foes? Emerging Impacts of Biological Toxins.

Clark GC, Casewell NR, Elliott CT, Harvey AL, Jamieson AG, Strong PN, Turner AD.

Trends Biochem Sci. 2019 Apr;44(4):365-379. doi: 10.1016/j.tibs.2018.12.004. Epub 2019 Jan 14. Review.


Crude oil removal from aqueous solution using raw and carbonized Xanthoceras sorbifolia shells.

Liu L, Wang L, Song W, Yang L, Yin L, Xia S, Wang H, Strong PJ, Song Z.

Environ Sci Pollut Res Int. 2018 Oct;25(29):29325-29334. doi: 10.1007/s11356-018-2895-0. Epub 2018 Aug 18.


Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes.

Heath GR, Harrison PL, Strong PN, Evans SD, Miller K.

Soft Matter. 2018 Jul 25;14(29):6146-6154. doi: 10.1039/c8sm00707a.


Therapeutic Potential of a Scorpion Venom-Derived Antimicrobial Peptide and Its Homologs Against Antibiotic-Resistant Gram-Positive Bacteria.

Liu G, Yang F, Li F, Li Z, Lang Y, Shen B, Wu Y, Li W, Harrison PL, Strong PN, Xie Y, Miller K, Cao Z.

Front Microbiol. 2018 May 29;9:1159. doi: 10.3389/fmicb.2018.01159. eCollection 2018.


Current approaches to the discovery of novel inhaled medicines.

Strong P, Ito K, Murray J, Rapeport G.

Drug Discov Today. 2018 Oct;23(10):1705-1717. doi: 10.1016/j.drudis.2018.05.017. Epub 2018 May 20. Review.


Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.

Brookes DW, Coates M, Allen H, Daly L, Constant S, Huang S, Hows M, Davis A, Cass L, Ayrton J, Knowles I, Strong P, Rapeport G, Ito K.

Br J Pharmacol. 2018 Jun;175(12):2520-2534. doi: 10.1111/bph.14221. Epub 2018 May 2.


The ideal use of dogs in medicine.

Rescigno G, Hogan J, Strong P.

Eur J Cardiothorac Surg. 2018 Jul 1;54(1):197. doi: 10.1093/ejcts/ezy041. No abstract available.


In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection.

Colley T, Sehra G, Chowdhary A, Alanio A, Kelly SL, Kizawa Y, Armstrong-James D, Fisher MC, Warrilow AGS, Parker JE, Kelly DE, Kimura G, Nishimoto Y, Sunose M, Onions S, Crepin D, Lagasse F, Crittall M, Shannon J, McConville M, King-Underwood J, Naylor A, Bretagne S, Murray J, Ito K, Strong P, Rapeport G.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e01941-17. doi: 10.1128/AAC.01941-17. Print 2018 May.


Effects of metal ions and pH on ofloxacin sorption to cassava residue-derived biochar.

Huang P, Ge C, Feng D, Yu H, Luo J, Li J, Strong PJ, Sarmah AK, Bolan NS, Wang H.

Sci Total Environ. 2018 Mar;616-617:1384-1391. doi: 10.1016/j.scitotenv.2017.10.177. Epub 2017 Oct 23.


Implementation of acute care patient portals: recommendations on utility and use from six early adopters.

Grossman LV, Choi SW, Collins S, Dykes PC, O'Leary KJ, Rizer M, Strong P, Yen PY, Vawdrey DK.

J Am Med Inform Assoc. 2018 Apr 1;25(4):370-379. doi: 10.1093/jamia/ocx074.


Contribution of forests to the carbon sink via biologically-mediated silicate weathering: A case study of China.

Song Z, Liu H, Strömberg CAE, Wang H, Strong PJ, Yang X, Wu Y.

Sci Total Environ. 2018 Feb 15;615:1-8. doi: 10.1016/j.scitotenv.2017.09.253. Epub 2017 Sep 29.


Effects of carbon source on methanogenic activities and pathways incorporating metagenomic analysis of microbial community.

Xing L, Yang S, Yin Q, Xie S, Strong PJ, Wu G.

Bioresour Technol. 2017 Nov;244(Pt 1):982-988. doi: 10.1016/j.biortech.2017.08.065. Epub 2017 Aug 12.


Microbial phylogeny determines transcriptional response of resistome to dynamic composting processes.

Wang C, Dong D, Strong PJ, Zhu W, Ma Z, Qin Y, Wu W.

Microbiome. 2017 Aug 16;5(1):103. doi: 10.1186/s40168-017-0324-0.


Effects of intranasally dosed posaconazole on fungal load and biomarkers in Aspergillus fumigatus infected immunocompromised mice.

Kimura G, Nakaoki T, Nishimoto Y, Suzuki Y, Rapeport G, Strong P, Ito K, Kizawa Y.

Mycoses. 2017 Nov;60(11):728-735. doi: 10.1111/myc.12653. Epub 2017 Jul 11.


Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor.

Coates M, Brookes D, Kim YI, Allen H, Fordyce EAF, Meals EA, Colley T, Ciana CL, Parra GF, Sherbukhin V, Stockwell JA, Thomas JC, Hunt SF, Anderson-Dring L, Onions ST, Cass L, Murray PJ, Ito K, Strong P, DeVincenzo JP, Rapeport G.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00737-17. doi: 10.1128/AAC.00737-17. Print 2017 Sep.


In Vivo Biomarker Analysis of the Effects of Intranasally Dosed PC945, a Novel Antifungal Triazole, on Aspergillus fumigatus Infection in Immunocompromised Mice.

Kimura G, Nakaoki T, Colley T, Rapeport G, Strong P, Ito K, Kizawa Y.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00124-17. doi: 10.1128/AAC.00124-17. Print 2017 Sep.


Discovery of novel benzothienoazepine derivatives as potent inhibitors of respiratory syncytial virus.

Fordyce EAF, Brookes DW, Lise-Ciana C, Coates MS, Hunt SF, Ito K, King-Underwood J, Onions ST, Parra GF, Rapeport G, Sherbukhin V, Stockwell JA, Strong P, Thomas JC, Murray J.

Bioorg Med Chem Lett. 2017 May 15;27(10):2201-2206. doi: 10.1016/j.bmcl.2017.03.053. Epub 2017 Mar 23.


In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection.

Colley T, Alanio A, Kelly SL, Sehra G, Kizawa Y, Warrilow AGS, Parker JE, Kelly DE, Kimura G, Anderson-Dring L, Nakaoki T, Sunose M, Onions S, Crepin D, Lagasse F, Crittall M, Shannon J, Cooke M, Bretagne S, King-Underwood J, Murray J, Ito K, Strong P, Rapeport G.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02280-16. doi: 10.1128/AAC.02280-16. Print 2017 May.


The Opportunity for High-Performance Biomaterials from Methane.

Strong PJ, Laycock B, Mahamud SN, Jensen PD, Lant PA, Tyson G, Pratt S.

Microorganisms. 2016 Feb 3;4(1). pii: E11. doi: 10.3390/microorganisms4010011. Review.


Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom.

Harrison PL, Heath GR, Johnson BRG, Abdel-Rahman MA, Strong PN, Evans SD, Miller K.

Biochim Biophys Acta. 2016 Nov;1858(11):2737-2744. doi: 10.1016/j.bbamem.2016.07.018. Epub 2016 Jul 30.


A methanotroph-based biorefinery: Potential scenarios for generating multiple products from a single fermentation.

Strong PJ, Kalyuzhnaya M, Silverman J, Clarke WP.

Bioresour Technol. 2016 Sep;215:314-323. doi: 10.1016/j.biortech.2016.04.099. Epub 2016 Apr 22. Review.


Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus.

Harrison PL, Abdel-Rahman MA, Strong PN, Tawfik MM, Miller K.

Toxicon. 2016 Jul;117:30-6. doi: 10.1016/j.toxicon.2016.03.014. Epub 2016 Mar 24.


Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma.

Onions ST, Ito K, Charron CE, Brown RJ, Colucci M, Frickel F, Hardy G, Joly K, King-Underwood J, Kizawa Y, Knowles I, Murray PJ, Novak A, Rani A, Rapeport G, Smith A, Strong P, Taddei DM, Williams JG.

J Med Chem. 2016 Mar 10;59(5):1727-46. doi: 10.1021/acs.jmedchem.5b01029. Epub 2016 Feb 4.


Engaging hospitalized patients in clinical care: Study protocol for a pragmatic randomized controlled trial.

Masterson Creber R, Prey J, Ryan B, Alarcon I, Qian M, Bakken S, Feiner S, Hripcsak G, Polubriaginof F, Restaino S, Schnall R, Strong P, Vawdrey D.

Contemp Clin Trials. 2016 Mar;47:165-71. doi: 10.1016/j.cct.2016.01.005. Epub 2016 Jan 18.


Biologically derived fertilizer: A multifaceted bio-tool in methane mitigation.

Singh JS, Strong PJ.

Ecotoxicol Environ Saf. 2016 Feb;124:267-276. doi: 10.1016/j.ecoenv.2015.10.018. Epub 2015 Nov 11. Review.


Evaluating the Environmental Health Effect of Bamboo-Derived Volatile Organic Compounds through Analysis the Metabolic Indices of the Disorder Animal Model.

Guo M, Hu ZQ, Strong PJ, Smit AM, Xu JW, Fan J, Wang HL.

Biomed Environ Sci. 2015 Aug;28(8):595-605. doi: 10.3967/bes2015.083.


In situ remediation technologies for mercury-contaminated soil.

He F, Gao J, Pierce E, Strong PJ, Wang H, Liang L.

Environ Sci Pollut Res Int. 2015 Jun;22(11):8124-47. doi: 10.1007/s11356-015-4316-y. Epub 2015 Apr 9. Review.


Methane as a resource: can the methanotrophs add value?

Strong PJ, Xie S, Clarke WP.

Environ Sci Technol. 2015 Apr 7;49(7):4001-18. doi: 10.1021/es504242n. Epub 2015 Mar 10. Review.


Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system.

Li J, Cheng W, Xu L, Strong PJ, Chen H.

Environ Sci Pollut Res Int. 2015 Mar;22(6):4587-96. doi: 10.1007/s11356-014-3665-2. Epub 2014 Oct 18.


Spectroscopic evidence for biochar amendment promoting humic acid synthesis and intensifying humification during composting.

Wang C, Tu Q, Dong D, Strong PJ, Wang H, Sun B, Wu W.

J Hazard Mater. 2014 Sep 15;280:409-16. doi: 10.1016/j.jhazmat.2014.08.030. Epub 2014 Aug 27.


The post-translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence.

Faulds-Pain A, Twine SM, Vinogradov E, Strong PC, Dell A, Buckley AM, Douce GR, Valiente E, Logan SM, Wren BW.

Mol Microbiol. 2014 Oct;94(2):272-89. doi: 10.1111/mmi.12755. Epub 2014 Sep 15.


Binding between lead ions and the high-abundance serum proteins.

Guo M, He L, Strong PJ, Wang H.

Chemosphere. 2014 Oct;112:472-80. doi: 10.1016/j.chemosphere.2014.05.018. Epub 2014 Jun 5.


Antimicrobial peptides from scorpion venoms.

Harrison PL, Abdel-Rahman MA, Miller K, Strong PN.

Toxicon. 2014 Sep;88:115-37. doi: 10.1016/j.toxicon.2014.06.006. Epub 2014 Jun 19. Review.


Identification and characterization of glycoproteins on the spore surface of Clostridium difficile.

Strong PC, Fulton KM, Aubry A, Foote S, Twine SM, Logan SM.

J Bacteriol. 2014 Jul;196(14):2627-37. doi: 10.1128/JB.01469-14. Epub 2014 May 9.


Repeated fear-induced diurnal rhythm disruptions predict PTSD-like sensitized physiological acute stress responses in F344 rats.

Thompson RS, Strong PV, Clark PJ, Maslanik TM, Wright KP Jr, Greenwood BN, Fleshner M.

Acta Physiol (Oxf). 2014 Jun;211(2):447-65. doi: 10.1111/apha.12239. Epub 2014 Feb 25.


Pentavalent single-domain antibodies reduce Campylobacter jejuni motility and colonization in chickens.

Riazi A, Strong PC, Coleman R, Chen W, Hirama T, van Faassen H, Henry M, Logan SM, Szymanski CM, Mackenzie R, Ghahroudi MA.

PLoS One. 2013 Dec 31;8(12):e83928. doi: 10.1371/journal.pone.0083928. eCollection 2013.


Investigating the candidacy of a lipoteichoic acid-based glycoconjugate as a vaccine to combat Clostridium difficile infection.

Cox AD, St Michael F, Aubry A, Cairns CM, Strong PC, Hayes AC, Logan SM.

Glycoconj J. 2013 Dec;30(9):843-55. doi: 10.1007/s10719-013-9489-3. Epub 2013 Aug 23.


Conus vexillum venom induces oxidative stress in Ehrlich's ascites carcinoma cells: an insight into the mechanism of induction.

Abdel-Rahman MA, Abdel-Nabi IM, El-Naggar MS, Abbas OA, Strong PN.

J Venom Anim Toxins Incl Trop Dis. 2013 May 1;19(1):10. doi: 10.1186/1678-9199-19-10.


Insight into the effects of biochar on manure composting: evidence supporting the relationship between N2O emission and denitrifying community.

Wang C, Lu H, Dong D, Deng H, Strong PJ, Wang H, Wu W.

Environ Sci Technol. 2013 Jul 2;47(13):7341-9. doi: 10.1021/es305293h. Epub 2013 Jun 19.


5-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise.

Greenwood BN, Strong PV, Loughridge AB, Day HE, Clark PJ, Mika A, Hellwinkel JE, Spence KG, Fleshner M.

PLoS One. 2012;7(9):e46118. doi: 10.1371/journal.pone.0046118. Epub 2012 Sep 25.


Biochemistry of envenomation.

Kaur P, Ghariwala V, Yeo KS, Tan HZ, Tan JC, Armugam A, Strong PN, Jeyaseelan K.

Adv Clin Chem. 2012;57:187-252. Review.


Phenotypic and genotypic characterizations of Campylobacter jejuni isolated from the broiler meat production process.

Kudirkienė E, Cohn MT, Stabler RA, Strong PC, Sernienė L, Wren BW, Nielsen EM, Malakauskas M, Brøndsted L.

Curr Microbiol. 2012 Oct;65(4):398-406. doi: 10.1007/s00284-012-0170-z. Epub 2012 Jun 27.


Assessment of anesthesia provides' opinions regarding pediatric induction practices in the state of Oklahoma.

de Armendi AJ, Mayhew JF, Shukry M, Seshachar A, Ponder J, Martinez M, Strong P, Cure JA.

J Okla State Med Assoc. 2012 Mar;105(3):92-6.


Physiological consequences of repeated exposures to conditioned fear.

Thompson RS, Strong PV, Fleshner M.

Behav Sci (Basel). 2012 May 18;2(2):57-78. doi: 10.3390/bs2020057. eCollection 2012 Jun.


Thermal and thermo-chemical pre-treatment of four waste residues and the effect on acetic acid production and methane synthesis.

Strong PJ, Gapes DJ.

Waste Manag. 2012 Sep;32(9):1669-77. doi: 10.1016/j.wasman.2012.04.004. Epub 2012 May 19.


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