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Items: 1 to 50 of 219

1.

TDP-43 aggregation inside micronuclei reveals a potential mechanism for protein inclusion formation in ALS.

Droppelmann CA, Campos-Melo D, Moszczynski AJ, Amzil H, Strong MJ.

Sci Rep. 2019 Dec 27;9(1):19928. doi: 10.1038/s41598-019-56483-y.

2.

Tau protein phosphorylation at Thr175 initiates fibril formation via accessibility of the N-terminal phosphatase-activating domain.

Hintermayer MA, Volkening K, Moszczynski AJ, Donison N, Strong MJ.

J Neurochem. 2019 Dec 19:e14942. doi: 10.1111/jnc.14942. [Epub ahead of print]

PMID:
31853971
3.

Robotic-Assisted Spinal Surgery: Current Generation Instrumentation and New Applications.

Elswick CM, Strong MJ, Joseph JR, Saadeh Y, Oppenlander M, Park P.

Neurosurg Clin N Am. 2020 Jan;31(1):103-110. doi: 10.1016/j.nec.2019.08.012. Epub 2019 Oct 25. Review.

PMID:
31739920
4.

Synergistic toxicity in an in vivo model of neurodegeneration through the co-expression of human TDP-43M337V and tauT175D protein.

Moszczynski AJ, Harvey M, Fulcher N, de Oliveira C, McCunn P, Donison N, Bartha R, Schmid S, Strong MJ, Volkening K.

Acta Neuropathol Commun. 2019 Nov 8;7(1):170. doi: 10.1186/s40478-019-0816-1.

5.

Neurofilament Immunohistochemistry Followed by Luxol Fast Blue, for Staining Axons and Myelin in the Same Paraffin Section of Spinal Cord.

Moszczynski AJ, Volkening K, Strong MJ.

Appl Immunohistochem Mol Morphol. 2019 Oct 24. doi: 10.1097/PAI.0000000000000814. [Epub ahead of print]

PMID:
31652146
6.

Genetic Variation in the Ontario Neurodegenerative Disease Research Initiative.

Dilliott AA, Evans EC, Farhan SMK, Ghani M, Sato C, Zhang M, McIntyre AD, Cao H, Racacho L, Robinson JF, Strong MJ, Masellis M, Bulman DE, Rogaeva E, Black SE, Finger E, Frank A, Freedman M, Hassan A, Lang A, Shoesmith CL, Swartz RH, Tang-Wai D, Tartaglia MC, Turnbull J, Zinman L; ONDRI Investigators, Hegele RA.

Can J Neurol Sci. 2019 Sep;46(5):491-498. doi: 10.1017/cjn.2019.228. Epub 2019 Aug 15.

PMID:
31217043
7.

Detection of Epstein-Barr Virus Infection in Non-Small Cell Lung Cancer.

Kheir F, Zhao M, Strong MJ, Yu Y, Nanbo A, Flemington EK, Morris GF, Reiss K, Li L, Lin Z.

Cancers (Basel). 2019 May 31;11(6). pii: E759. doi: 10.3390/cancers11060759.

8.

Reproducibility of Neurite Orientation Dispersion and Density Imaging (NODDI) in rats at 9.4 Tesla.

McCunn P, Gilbert KM, Zeman P, Li AX, Strong MJ, Khan AR, Bartha R.

PLoS One. 2019 Apr 29;14(4):e0215974. doi: 10.1371/journal.pone.0215974. eCollection 2019.

9.

Biomarkers of Pineal Region Tumors: A Review.

Carr C, O'Neill BE, Hochhalter CB, Strong MJ, Ware ML.

Ochsner J. 2019 Spring;19(1):26-31. doi: 10.31486/toj.18.0110. Review.

10.

Social parasitism as an alternative reproductive tactic in a cooperatively breeding cuckoo.

Riehl C, Strong MJ.

Nature. 2019 Mar;567(7746):96-99. doi: 10.1038/s41586-019-0981-1. Epub 2019 Feb 27.

PMID:
30814729
11.

A novel overlapping NLS/NES region within the PH domain of Rho Guanine Nucleotide Exchange Factor (RGNEF) regulates its nuclear-cytoplasmic localization.

Tavolieri MV, Droppelmann CA, Campos-Melo D, Volkening K, Strong MJ.

Eur J Cell Biol. 2019 Jan;98(1):27-35. doi: 10.1016/j.ejcb.2018.11.001. Epub 2018 Nov 19.

PMID:
30482479
12.

MiR-105 and miR-9 regulate the mRNA stability of neuronal intermediate filaments. Implications for the pathogenesis of amyotrophic lateral sclerosis (ALS).

Hawley ZCE, Campos-Melo D, Strong MJ.

Brain Res. 2019 Mar 1;1706:93-100. doi: 10.1016/j.brainres.2018.10.032. Epub 2018 Oct 29.

PMID:
30385300
13.

Reply: TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

Tétreault M, Deshaies JE, Semmler S, Sidibé H, Shkreta L, Volkening K, Soreq H, Strong MJ, Chabot B, Vande Velde C.

Brain. 2018 Dec 1;141(12):e84. doi: 10.1093/brain/awy261. No abstract available.

14.

Advances in Neuro-Oncology Imaging Techniques.

O'Neill BE, Hochhalter CB, Carr C, Strong MJ, Ware ML.

Ochsner J. 2018 Fall;18(3):236-241. doi: 10.31486/toj.17.0062. Review.

15.

Author response: Pathologic Thr175 tau phosphorylation in CTE and CTE with ALS.

Strong MJ.

Neurology. 2018 Sep 18;91(12):579. doi: 10.1212/WNL.0000000000006194. No abstract available.

PMID:
30224505
16.

Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs.

Campos-Melo D, Hawley ZCE, Strong MJ.

Mol Brain. 2018 Jul 20;11(1):43. doi: 10.1186/s13041-018-0386-3.

17.

Somatic Gene Transfer Using a Recombinant Adenoviral Vector (rAAV9) Encoding Pseudophosphorylated Human Thr175 Tau in Adult Rat Hippocampus Induces Tau Pathology.

Moszczynski AJ, Gopaul J, McCunn P, Volkening K, Harvey M, Bartha R, Schmid S, Strong MJ.

J Neuropathol Exp Neurol. 2018 Aug 1;77(8):685-695. doi: 10.1093/jnen/nly044.

PMID:
29878234
18.

Correction to "RNA and Protein Interactors with TDP-43 in Human Spinal-Cord Lysates in Amyotrophic Lateral Sclerosis".

Volkening K, Keller BA, Leystra-Lantz C, Strong MJ.

J Proteome Res. 2018 Jun 1;17(6):2248. doi: 10.1021/acs.jproteome.8b00261. Epub 2018 May 8. No abstract available.

PMID:
29737853
19.

Phosphorylation of Threonine 175 Tau in the Induction of Tau Pathology in Amyotrophic Lateral Sclerosis-Frontotemporal Spectrum Disorder (ALS-FTSD). A Review.

Moszczynski AJ, Hintermayer MA, Strong MJ.

Front Neurosci. 2018 Apr 20;12:259. doi: 10.3389/fnins.2018.00259. eCollection 2018. Review.

20.

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease.

Dilliott AA, Farhan SMK, Ghani M, Sato C, Liang E, Zhang M, McIntyre AD, Cao H, Racacho L, Robinson JF, Strong MJ, Masellis M, Bulman DE, Rogaeva E, Lang A, Tartaglia C, Finger E, Zinman L, Turnbull J, Freedman M, Swartz R, Black SE, Hegele RA.

J Vis Exp. 2018 Apr 4;(134). doi: 10.3791/57266.

21.

Stable social relationships between unrelated females increase individual fitness in a cooperative bird.

Riehl C, Strong MJ.

Proc Biol Sci. 2018 Apr 11;285(1876). pii: 20180130. doi: 10.1098/rspb.2018.0130.

22.

TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.

Deshaies JE, Shkreta L, Moszczynski AJ, Sidibé H, Semmler S, Fouillen A, Bennett ER, Bekenstein U, Destroismaisons L, Toutant J, Delmotte Q, Volkening K, Stabile S, Aulas A, Khalfallah Y, Soreq H, Nanci A, Strong MJ, Chabot B, Vande Velde C.

Brain. 2018 May 1;141(5):1320-1333. doi: 10.1093/brain/awy062.

23.

RNA and Protein Interactors with TDP-43 in Human Spinal-Cord Lysates in Amyotrophic Lateral Sclerosis.

Volkening K, Keller BA, Leystra-Lantz C, Strong MJ.

J Proteome Res. 2018 Apr 6;17(4):1712-1729. doi: 10.1021/acs.jproteome.8b00126. Epub 2018 Mar 22. Erratum in: J Proteome Res. 2018 Jun 1;17(6):2248.

PMID:
29513014
24.

Pathologic Thr175 tau phosphorylation in CTE and CTE with ALS.

Moszczynski AJ, Strong W, Xu K, McKee A, Brown A, Strong MJ.

Neurology. 2018 Jan 30;90(5):e380-e387. doi: 10.1212/WNL.0000000000004899. Epub 2018 Jan 3.

25.

Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα.

Tortarolo M, Lo Coco D, Veglianese P, Vallarola A, Giordana MT, Marcon G, Beghi E, Poloni M, Strong MJ, Iyer AM, Aronica E, Bendotti C.

Mediators Inflamm. 2017;2017:2985051. doi: 10.1155/2017/2985051. Epub 2017 Sep 10. Review.

26.

OPTN p.Met468Arg and ATXN2 intermediate length polyQ extension in families with C9orf72 mediated amyotrophic lateral sclerosis and frontotemporal dementia.

Farhan SMK, Gendron TF, Petrucelli L, Hegele RA, Strong MJ.

Am J Med Genet B Neuropsychiatr Genet. 2018 Jan;177(1):75-85. doi: 10.1002/ajmg.b.32606. Epub 2017 Oct 28.

PMID:
29080331
27.

ARHGEF28 p.Lys280Metfs40Ter in an amyotrophic lateral sclerosis family with a C9orf72 expansion.

Farhan SMK, Gendron TF, Petrucelli L, Hegele RA, Strong MJ.

Neurol Genet. 2017 Sep 22;3(5):e190. doi: 10.1212/NXG.0000000000000190. eCollection 2017 Oct. No abstract available.

28.

Novel miR-b2122 regulates several ALS-related RNA-binding proteins.

Hawley ZCE, Campos-Melo D, Strong MJ.

Mol Brain. 2017 Oct 2;10(1):46. doi: 10.1186/s13041-017-0326-7.

29.

A Pivotal Randomized Clinical Trial Evaluating the Safety and Effectiveness of a Novel Hydrogel Dural Sealant as an Adjunct to Dural Repair.

Strong MJ, West GA, Woo H, Couture DE, Wilson JA, Munoz LF, Rosen CL, Greenlee JD, van Loveren HR, Iantosca M, Baird CJ, Smith M, McGirt M, Parish J, Asher AL.

Oper Neurosurg (Hagerstown). 2017 Apr 1;13(2):204-212. doi: 10.1093/ons/opw004.

PMID:
28927211
30.

Revisiting the concept of amyotrophic lateral sclerosis as a multisystems disorder of limited phenotypic expression.

Strong MJ.

Curr Opin Neurol. 2017 Dec;30(6):599-607. doi: 10.1097/WCO.0000000000000488. Review.

PMID:
28914734
31.

The Rising Challenge of Training Physician-Scientists: Recommendations From a Canadian National Consensus Conference.

Strong MJ, Busing N, Goosney DL, Harris KA, Horsley T, Kuzyk A, Lingard L, Norman WV, Rosenblum ND, Saryeddine T, Wang X.

Acad Med. 2018 Feb;93(2):172-178. doi: 10.1097/ACM.0000000000001857.

PMID:
28817429
32.

Motor Phenotype in Neurodegenerative Disorders: Gait and Balance Platform Study Design Protocol for the Ontario Neurodegenerative Research Initiative (ONDRI).

Montero-Odasso M, Pieruccini-Faria F, Bartha R, Black SE, Finger E, Freedman M, Greenberg B, Grimes DA, Hegele RA, Hudson C, Kleinstiver PW, Lang AE, Masellis M, McLaughlin PM, Munoz DP, Strother S, Swartz RH, Symons S, Tartaglia MC, Zinman L, Strong MJ; ONDRI Investigators, McIlroy W.

J Alzheimers Dis. 2017;59(2):707-721. doi: 10.3233/JAD-170149.

33.

C9orf72 mutations do not influence the tau signature of amyotrophic lateral sclerosis with cognitive impairment (ALSci).

Volkening K, Strong WL, Seaton S, Yang W, Strong MJ.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Nov;18(7-8):549-554. doi: 10.1080/21678421.2017.1332075. Epub 2017 May 31.

PMID:
28562075
34.

MotomiRs: miRNAs in Motor Neuron Function and Disease.

Hawley ZCE, Campos-Melo D, Droppelmann CA, Strong MJ.

Front Mol Neurosci. 2017 May 4;10:127. doi: 10.3389/fnmol.2017.00127. eCollection 2017. Review.

35.

Rho guanine nucleotide exchange factor (RGNEF) is a prosurvival factor under stress conditions.

Cheung K, Droppelmann CA, MacLellan A, Cameron I, Withers B, Campos-Melo D, Volkening K, Strong MJ.

Mol Cell Neurosci. 2017 Jul;82:88-95. doi: 10.1016/j.mcn.2017.05.003. Epub 2017 May 8.

PMID:
28495450
36.

Interaction of Epstein-Barr virus genes with human gastric carcinoma transcriptome.

Zhang R, Strong MJ, Baddoo M, Lin Z, Wang YP, Flemington EK, Liu YZ.

Oncotarget. 2017 Jun 13;8(24):38399-38412. doi: 10.18632/oncotarget.16417.

37.

Threonine175, a novel pathological phosphorylation site on tau protein linked to multiple tauopathies.

Moszczynski AJ, Yang W, Hammond R, Ang LC, Strong MJ.

Acta Neuropathol Commun. 2017 Jan 11;5(1):6. doi: 10.1186/s40478-016-0406-4.

38.

Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria.

Strong MJ, Abrahams S, Goldstein LH, Woolley S, Mclaughlin P, Snowden J, Mioshi E, Roberts-South A, Benatar M, HortobáGyi T, Rosenfeld J, Silani V, Ince PG, Turner MR.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 May;18(3-4):153-174. doi: 10.1080/21678421.2016.1267768. Epub 2017 Jan 5. Review.

PMID:
28054827
39.

The Ontario Neurodegenerative Disease Research Initiative (ONDRI).

Farhan SM, Bartha R, Black SE, Corbett D, Finger E, Freedman M, Greenberg B, Grimes DA, Hegele RA, Hudson C, Kleinstiver PW, Lang AE, Masellis M, McIlroy WE, McLaughlin PM, Montero-Odasso M, Munoz DG, Munoz DP, Strother S, Swartz RH, Symons S, Tartaglia MC, Zinman L; ONDRI Investigators, Strong MJ.

Can J Neurol Sci. 2017 Mar;44(2):196-202. doi: 10.1017/cjn.2016.415. Epub 2016 Dec 22.

PMID:
28003035
40.

The ONDRISeq panel: custom-designed next-generation sequencing of genes related to neurodegeneration.

Farhan SMK, Dilliott AA, Ghani M, Sato C, Liang E, Zhang M, McIntyre AD, Cao H, Racacho L, Robinson JF, Strong MJ, Masellis M, St George-Hyslop P, Bulman DE, Rogaeva E, Hegele RA; ONDRI Investigators.

NPJ Genom Med. 2016 Sep 21;1:16032. doi: 10.1038/npjgenmed.2016.32. eCollection 2016.

41.

A comprehensive next generation sequencing-based virome assessment in brain tissue suggests no major virus - tumor association.

Strong MJ, Blanchard E 4th, Lin Z, Morris CA, Baddoo M, Taylor CM, Ware ML, Flemington EK.

Acta Neuropathol Commun. 2016 Jul 11;4(1):71. doi: 10.1186/s40478-016-0338-z.

42.

Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma.

Zhang J, Baddoo M, Han C, Strong MJ, Cvitanovic J, Moroz K, Dash S, Flemington EK, Wu T.

Oncotarget. 2016 Aug 2;7(31):49232-49245. doi: 10.18632/oncotarget.10249.

43.

Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy.

Behrouzi R, Liu X, Wu D, Robinson AC, Tanaguchi-Watanabe S, Rollinson S, Shi J, Tian J, Hamdalla HH, Ealing J, Richardson A, Jones M, Pickering-Brown S, Davidson YS, Strong MJ, Hasegawa M, Snowden JS, Mann DM.

Acta Neuropathol Commun. 2016 Mar 31;4:33. doi: 10.1186/s40478-016-0301-z.

44.

Secreted Oral Epithelial Cell Membrane Vesicles Induce Epstein-Barr Virus Reactivation in Latently Infected B Cells.

Lin Z, Swan K, Zhang X, Cao S, Brett Z, Drury S, Strong MJ, Fewell C, Puetter A, Wang X, Ferris M, Sullivan DE, Li L, Flemington EK.

J Virol. 2016 Jan 13;90(7):3469-79. doi: 10.1128/JVI.02830-15.

45.

Correction for Strong et al., Epstein-Barr Virus and Human Herpesvirus 6 Detection in a Non-Hodgkin's Diffuse Large B-Cell Lymphoma Cohort by Using RNA Sequencing.

Strong MJ, O'Grady T, Lin Z, Xu G, Baddoo M, Parsons C, Zhang K, Taylor CM, Flemington EK.

J Virol. 2015 Dec 30;90(2):1152. doi: 10.1128/JVI.02772-15. Print 2016 Jan 15. No abstract available.

46.

Frontotemporal Dysfunction and Dementia in Amyotrophic Lateral Sclerosis.

Woolley SC, Strong MJ.

Neurol Clin. 2015 Nov;33(4):787-805. doi: 10.1016/j.ncl.2015.07.011. Epub 2015 Sep 8. Review.

PMID:
26515622
47.

Treatment of recurrent metastatic uterine leiomyosarcoma of the spine: a multimodality approach using resection, radiosurgery, and chemotherapy.

Strong MJ, Rosenlof T, Padmanabha S, Weiner RS, Morgan LR, Ware MI.

J Neurosurg Spine. 2015 Nov;23(5):607-612. doi: 10.3171/2015.1.SPINE14640. Epub 2015 Jul 17.

48.

Latent Expression of the Epstein-Barr Virus (EBV)-Encoded Major Histocompatibility Complex Class I TAP Inhibitor, BNLF2a, in EBV-Positive Gastric Carcinomas.

Strong MJ, Laskow T, Nakhoul H, Blanchard E, Liu Y, Wang X, Baddoo M, Lin Z, Yin Q, Flemington EK.

J Virol. 2015 Oct;89(19):10110-4. doi: 10.1128/JVI.01110-15. Epub 2015 Jul 15.

49.

Benign Sacral Metastatic Meningioma: A Rare Entity.

Strong MJ, Garces J, Tang W, Ware ML.

Ochsner J. 2015 Summer;15(2):200-2.

50.

New Noncoding Lytic Transcripts Derived from the Epstein-Barr Virus Latency Origin of Replication, oriP, Are Hyperedited, Bind the Paraspeckle Protein, NONO/p54nrb, and Support Viral Lytic Transcription.

Cao S, Moss W, O'Grady T, Concha M, Strong MJ, Wang X, Yu Y, Baddoo M, Zhang K, Fewell C, Lin Z, Dong Y, Flemington EK.

J Virol. 2015 Jul;89(14):7120-32. doi: 10.1128/JVI.00608-15. Epub 2015 Apr 29.

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