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Items: 1 to 50 of 232

1.

Repression of Germline Genes in Caenorhabditis elegans Somatic Tissues by H3K9 Dimethylation of Their Promoters.

Rechtsteiner A, Costello ME, Egelhofer TA, Garrigues JM, Strome S, Petrella LN.

Genetics. 2019 May;212(1):125-140. doi: 10.1534/genetics.118.301878. Epub 2019 Mar 25.

2.

Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans.

Kaneshiro KR, Rechtsteiner A, Strome S.

Nat Commun. 2019 Mar 20;10(1):1271. doi: 10.1038/s41467-019-09141-w.

3.

NK cell expression of Tim-3: First impressions matter.

So EC, Khaladj-Ghom A, Ji Y, Amin J, Song Y, Burch E, Zhou H, Sun H, Chen S, Bentzen S, Hertzano R, Zhang X, Strome SE.

Immunobiology. 2019 May;224(3):362-370. doi: 10.1016/j.imbio.2019.03.001. Epub 2019 Mar 2.

4.

Intratumor genetic heterogeneity in squamous cell carcinoma of the oral cavity.

Zandberg DP, Tallon LJ, Nagaraj S, Sadzewicz LK, Zhang Y, Strome MB, Zhao XE, Vavikolanu K, Zhang X, Papadimitriou JC, Hubbard FA, Bentzen SM, Strome SE, Fraser CM.

Head Neck. 2019 Mar 14. doi: 10.1002/hed.25719. [Epub ahead of print]

PMID:
30869813
5.

The evolving role of immuno-oncology for the treatment of head and neck cancer.

Strome AL, Zhang X, Strome SE.

Laryngoscope Investig Otolaryngol. 2019 Jan 10;4(1):62-69. doi: 10.1002/lio2.235. eCollection 2019 Feb. Review.

6.

A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity.

Zhang X, Owens J, Olsen HS, So E, Burch E, McCroskey MC, Li X, Weber GL, Bennett D, Rybin D, Zhou H, Hao H, Mérigeon EY, Block DS, LaRosa G, Strome SE.

JCI Insight. 2019 Jan 24;4(2). pii: 121905. doi: 10.1172/jci.insight.121905. [Epub ahead of print]

7.

Is routine genetic testing warranted in head and neck paragangliomas?

Gupta N, Strome SE, Hatten KM.

Laryngoscope. 2018 Dec 27. doi: 10.1002/lary.27656. [Epub ahead of print] No abstract available.

PMID:
30588632
8.

Caenorhabditis elegans sperm carry a histone-based epigenetic memory of both spermatogenesis and oogenesis.

Tabuchi TM, Rechtsteiner A, Jeffers TE, Egelhofer TA, Murphy CT, Strome S.

Nat Commun. 2018 Oct 17;9(1):4310. doi: 10.1038/s41467-018-06236-8.

9.

Distinct Roles of Two Histone Methyltransferases in Transmitting H3K36me3-Based Epigenetic Memory Across Generations in Caenorhabditis elegans.

Kreher J, Takasaki T, Cockrum C, Sidoli S, Garcia BA, Jensen ON, Strome S.

Genetics. 2018 Nov;210(3):969-982. doi: 10.1534/genetics.118.301353. Epub 2018 Sep 14.

10.

A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b.

Zhou H, Olsen H, So E, Mérigeon E, Rybin D, Owens J, LaRosa G, Block DS, Strome SE, Zhang X.

Blood Adv. 2017 Mar 14;1(8):504-515. doi: 10.1182/bloodadvances.2016001917. eCollection 2017 Mar 14.

11.

Loss of the Caenorhabditis elegans pocket protein LIN-35 reveals MuvB's innate function as the repressor of DREAM target genes.

Goetsch PD, Garrigues JM, Strome S.

PLoS Genet. 2017 Nov 1;13(11):e1007088. doi: 10.1371/journal.pgen.1007088. eCollection 2017 Nov.

12.

Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease.

Sun H, Olsen HS, Mérigeon EY, So E, Burch E, Kinsey S, Papadimitriou JC, Drachenberg CB, Bentzen SM, Block DS, Strome SE, Zhang X.

J Autoimmun. 2017 Nov;84:97-108. doi: 10.1016/j.jaut.2017.08.004. Epub 2017 Aug 19.

PMID:
28830653
13.

Correction: A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans.

Ahn JH, Rechtsteiner A, Strome S, Kelly WG.

PLoS Genet. 2017 May 31;13(5):e1006821. doi: 10.1371/journal.pgen.1006821. eCollection 2017 May.

14.

What additional treatment is indicated for oral cavity cancer with isolated perineural invasion?

Hatten KM, Gupta N, Strome SE.

Laryngoscope. 2017 Sep;127(9):1965-1966. doi: 10.1002/lary.26577. Epub 2017 Mar 27. Review. No abstract available.

PMID:
28349551
15.

Germ Granules Prevent Accumulation of Somatic Transcripts in the Adult Caenorhabditis elegans Germline.

Knutson AK, Egelhofer T, Rechtsteiner A, Strome S.

Genetics. 2017 May;206(1):163-178. doi: 10.1534/genetics.116.198549. Epub 2017 Mar 3.

16.

Inheritance of protection from osmotic stress.

Kaneshiro KR, Strome S.

Nat Cell Biol. 2017 Mar 1;19(3):151-152. doi: 10.1038/ncb3483.

17.

Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model.

Levin D, Lagassé HA, Burch E, Strome S, Tan S, Jiang H, Sauna ZE, Golding B.

J Thromb Haemost. 2017 Apr;15(4):721-734. doi: 10.1111/jth.13649. Epub 2017 Mar 2.

18.

Elements of Access: The Effects of Food Outlet Proximity, Transportation, and Realized Access on Fresh Fruit and Vegetable Consumption in Food Deserts.

Strome S, Johns T, Scicchitano MJ, Shelnutt K.

Int Q Community Health Educ. 2016 Oct;37(1):61-70. doi: 10.1177/0272684X16685252. Epub 2016 Dec 30.

PMID:
28038499
19.

Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting.

Bauman JE, Cohen E, Ferris RL, Adelstein DJ, Brizel DM, Ridge JA, O'Sullivan B, Burtness BA, Butterfield LH, Carson WE, Disis ML, Fox BA, Gajewski TF, Gillison ML, Hodge JW, Le QT, Raben D, Strome SE, Lynn J, Malik S.

Cancer. 2017 Apr 1;123(7):1259-1271. doi: 10.1002/cncr.30449. Epub 2016 Dec 1.

20.

A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans.

Ahn JH, Rechsteiner A, Strome S, Kelly WG.

PLoS Genet. 2016 Aug 19;12(8):e1006227. doi: 10.1371/journal.pgen.1006227. eCollection 2016 Aug. Erratum in: PLoS Genet. 2017 May 31;13(5):e1006821.

21.

The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment.

Pai SI, Zandberg DP, Strome SE.

Oral Oncol. 2016 Oct;61:152-8. doi: 10.1016/j.oraloncology.2016.08.001. Epub 2016 Aug 5. Review.

22.

Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters.

Marceau AH, Felthousen JG, Goetsch PD, Iness AN, Lee HW, Tripathi SM, Strome S, Litovchick L, Rubin SM.

Nat Commun. 2016 Jul 28;7:12301. doi: 10.1038/ncomms12301.

23.

Reevaluation of whether a soma-to-germ-line transformation extends lifespan in Caenorhabditis elegans.

Knutson AK, Rechtsteiner A, Strome S.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3591-6. doi: 10.1073/pnas.1523402113. Epub 2016 Mar 14.

24.

Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease.

Zhang X, Olsen HS, Chen S, So E, Zhou H, Burch E, Mérigeon EY, Block DS, Strome SE.

J Immunol. 2016 Feb 1;196(3):1165-76. doi: 10.4049/jimmunol.1501755. Epub 2015 Dec 22.

25.

Caenorhabditis elegans polo-like kinase PLK-1 is required for merging parental genomes into a single nucleus.

Rahman MM, Munzig M, Kaneshiro K, Lee B, Strome S, Müller-Reichert T, Cohen-Fix O.

Mol Biol Cell. 2015 Dec 15;26(25):4718-35. doi: 10.1091/mbc.E15-04-0244. Epub 2015 Oct 21.

26.

RFX transcription factors are essential for hearing in mice.

Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R.

Nat Commun. 2015 Oct 15;6:8549. doi: 10.1038/ncomms9549.

27.

Impact of Detachment Methods on M2 Macrophage Phenotype and Function.

Chen S, So EC, Strome SE, Zhang X.

J Immunol Methods. 2015 Nov;426:56-61. doi: 10.1016/j.jim.2015.08.001. Epub 2015 Aug 5.

PMID:
26253940
28.

Specifying and protecting germ cell fate.

Strome S, Updike D.

Nat Rev Mol Cell Biol. 2015 Jul;16(7):406-16. doi: 10.1038/nrm4009. Review.

29.

The DREAM complex promotes gene body H2A.Z for target repression.

Latorre I, Chesney MA, Garrigues JM, Stempor P, Appert A, Francesconi M, Strome S, Ahringer J.

Genes Dev. 2015 Mar 1;29(5):495-500. doi: 10.1101/gad.255810.114.

30.

Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional.

Sun W, Wang Y, East JE, Kimball AS, Tkaczuk K, Kesmodel S, Strome SE, Webb TJ.

Cytokine. 2015 Mar;72(1):48-57. doi: 10.1016/j.cyto.2014.12.009. Epub 2015 Jan 5.

31.

A phase I dose escalation trial of MAGE-A3- and HPV16-specific peptide immunomodulatory vaccines in patients with recurrent/metastatic (RM) squamous cell carcinoma of the head and neck (SCCHN).

Zandberg DP, Rollins S, Goloubeva O, Morales RE, Tan M, Taylor R, Wolf JS, Schumaker LM, Cullen KJ, Zimrin A, Ord R, Lubek JE, Suntharalingam M, Papadimitriou JC, Mann D, Strome SE, Edelman MJ.

Cancer Immunol Immunother. 2015 Mar;64(3):367-79. doi: 10.1007/s00262-014-1640-x. Epub 2014 Dec 24.

32.

Oropharyngeal cancer as a driver of racial outcome disparities in squamous cell carcinoma of the head and neck: 10-year experience at the University of Maryland Greenebaum Cancer Center.

Zandberg DP, Liu S, Goloubeva O, Ord R, Strome SE, Suntharalingam M, Taylor R, Morales RE, Wolf JS, Zimrin A, Lubek JE, Schumaker LM, Cullen KJ.

Head Neck. 2016 Apr;38(4):564-72. doi: 10.1002/hed.23933. Epub 2015 Jun 30.

33.

Fc fusion as a platform technology: potential for modulating immunogenicity.

Levin D, Golding B, Strome SE, Sauna ZE.

Trends Biotechnol. 2015 Jan;33(1):27-34. doi: 10.1016/j.tibtech.2014.11.001. Epub 2014 Dec 6. Review.

PMID:
25488117
34.

Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2.

Garrigues JM, Sidoli S, Garcia BA, Strome S.

Genome Res. 2015 Jan;25(1):76-88. doi: 10.1101/gr.180489.114. Epub 2014 Dec 2.

35.

Gene repression. H3K27me and PRC2 transmit a memory of repression across generations and during development.

Gaydos LJ, Wang W, Strome S.

Science. 2014 Sep 19;345(6203):1515-8. doi: 10.1126/science.1255023. Epub 2014 Sep 18.

36.

Comparative analysis of metazoan chromatin organization.

Ho JW, Jung YL, Liu T, Alver BH, Lee S, Ikegami K, Sohn KA, Minoda A, Tolstorukov MY, Appert A, Parker SC, Gu T, Kundaje A, Riddle NC, Bishop E, Egelhofer TA, Hu SS, Alekseyenko AA, Rechtsteiner A, Asker D, Belsky JA, Bowman SK, Chen QB, Chen RA, Day DS, Dong Y, Dose AC, Duan X, Epstein CB, Ercan S, Feingold EA, Ferrari F, Garrigues JM, Gehlenborg N, Good PJ, Haseley P, He D, Herrmann M, Hoffman MM, Jeffers TE, Kharchenko PV, Kolasinska-Zwierz P, Kotwaliwale CV, Kumar N, Langley SA, Larschan EN, Latorre I, Libbrecht MW, Lin X, Park R, Pazin MJ, Pham HN, Plachetka A, Qin B, Schwartz YB, Shoresh N, Stempor P, Vielle A, Wang C, Whittle CM, Xue H, Kingston RE, Kim JH, Bernstein BE, Dernburg AF, Pirrotta V, Kuroda MI, Noble WS, Tullius TD, Kellis M, MacAlpine DM, Strome S, Elgin SC, Liu XS, Lieb JD, Ahringer J, Karpen GH, Park PJ.

Nature. 2014 Aug 28;512(7515):449-52. doi: 10.1038/nature13415.

37.

Immature teratoma of the maxillary sinus: a rare pediatric tumor.

Chang AE, Ambro BT, Strome SE, Papadimitriou JC, Pereira KD.

JAMA Otolaryngol Head Neck Surg. 2014 Sep;140(9):870-2. doi: 10.1001/jamaoto.2014.1800.

PMID:
25144659
38.

The anti-lymphoma activities of anti-CD137 monoclonal antibodies are enhanced in FcγRIII(-/-) mice.

Sallin MA, Zhang X, So EC, Burch E, Cai L, Lin W, Chapoval AI, Strome SE.

Cancer Immunol Immunother. 2014 Sep;63(9):947-58. doi: 10.1007/s00262-014-1567-2. Epub 2014 Jun 14.

PMID:
24927849
39.

The role of the PD-L1:PD-1 pathway in squamous cell carcinoma of the head and neck.

Zandberg DP, Strome SE.

Oral Oncol. 2014 Jul;50(7):627-32. doi: 10.1016/j.oraloncology.2014.04.003. Epub 2014 May 10. Review.

PMID:
24819861
40.

Germ-granule components prevent somatic development in the C. elegans germline.

Updike DL, Knutson AK, Egelhofer TA, Campbell AC, Strome S.

Curr Biol. 2014 May 5;24(9):970-5. doi: 10.1016/j.cub.2014.03.015. Epub 2014 Apr 17.

41.

In response to What are the best management strategies for radiation-induced xerostomia?

Hutchinson CT, Strome SE, Suntharalingam M.

Laryngoscope. 2014 Sep;124(9):E397. doi: 10.1002/lary.24675. Epub 2014 Apr 29. No abstract available.

PMID:
24623594
42.

Regulation of the X chromosomes in Caenorhabditis elegans.

Strome S, Kelly WG, Ercan S, Lieb JD.

Cold Spring Harb Perspect Biol. 2014 Mar 1;6(3). pii: a018366. doi: 10.1101/cshperspect.a018366. Review.

43.

Combination immunotherapy after ASCT for multiple myeloma using MAGE-A3/Poly-ICLC immunizations followed by adoptive transfer of vaccine-primed and costimulated autologous T cells.

Rapoport AP, Aqui NA, Stadtmauer EA, Vogl DT, Xu YY, Kalos M, Cai L, Fang HB, Weiss BM, Badros A, Yanovich S, Akpek G, Tsao P, Cross A, Mann D, Philip S, Kerr N, Brennan A, Zheng Z, Ruehle K, Milliron T, Strome SE, Salazar AM, Levine BL, June CH.

Clin Cancer Res. 2014 Mar 1;20(5):1355-65. doi: 10.1158/1078-0432.CCR-13-2817. Epub 2014 Feb 11.

44.

Opposing activities of DRM and MES-4 tune gene expression and X-chromosome repression in Caenorhabditis elegans germ cells.

Tabuchi TM, Rechtsteiner A, Strome S, Hagstrom KA.

G3 (Bethesda). 2014 Jan 10;4(1):143-53. doi: 10.1534/g3.113.007849.

45.

What are the best management strategies for radiation-induced xerostomia?

Hutchinson CT, Suntharalingam M, Strome SE.

Laryngoscope. 2014 Feb;124(2):359-60. doi: 10.1002/lary.24035. Epub 2013 Sep 19. Review. No abstract available.

PMID:
24105656
46.

Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer.

Jain A, Poonia B, So EC, Vyzasatya R, Burch EE, Olsen HS, Mérigeon EY, Block DS, Zhang X, Schulze DH, Hanna NN, Twadell WS, Yfantis HG, Chan SL, Cai L, Strome SE.

Eur J Cancer. 2013 Oct;49(15):3344-52. doi: 10.1016/j.ejca.2013.06.009. Epub 2013 Jul 18.

PMID:
23871153
47.

Surgical management of craniofacial neurofibromatosis type 1 associated tumors.

Janes LE, Sabino J, Matthews JA, Papadimitriou JC, Strome SE, Singh DP.

J Craniofac Surg. 2013 Jul;24(4):1273-7. doi: 10.1097/SCS.0b013e318285d337. Review.

PMID:
23851786
48.

CD40 mediates downregulation of CD32B on specific memory B cell populations in rheumatoid arthritis.

Zhang X, Burch E, Cai L, So E, Hubbard F, Matteson EL, Strome SE.

J Immunol. 2013 Jun 15;190(12):6015-22. doi: 10.4049/jimmunol.1203366. Epub 2013 May 17.

49.

A high throughput method for enrichment of natural killer cells and lymphocytes and assessment of in vitro cytotoxicity.

So EC, Sallin MA, Zhang X, Chan SL, Sahni L, Schulze DH, Davila E, Strome SE, Jain A.

J Immunol Methods. 2013 Aug 30;394(1-2):40-8. doi: 10.1016/j.jim.2013.05.001. Epub 2013 May 13.

PMID:
23680234
50.

Restoring immune function of tumor-specific CD4+ T cells during recurrence of melanoma.

Goding SR, Wilson KA, Xie Y, Harris KM, Baxi A, Akpinarli A, Fulton A, Tamada K, Strome SE, Antony PA.

J Immunol. 2013 May 1;190(9):4899-909. doi: 10.4049/jimmunol.1300271. Epub 2013 Mar 27.

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