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Items: 1 to 50 of 77

1.

Bispecific T-Cell Redirection versus Chimeric Antigen Receptor (CAR)-T Cells as Approaches to Kill Cancer Cells.

Strohl WR, Naso M.

Antibodies (Basel). 2019 Jul 3;8(3). pii: E41. doi: 10.3390/antib8030041. Review.

2.

Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus.

Chan R, Buckley PT, O'Malley A, Sause WE, Alonzo F 3rd, Lubkin A, Boguslawski KM, Payne A, Fernandez J, Strohl WR, Whitaker B, Lynch AS, Torres VJ.

Sci Transl Med. 2019 Jan 16;11(475). pii: eaat0882. doi: 10.1126/scitranslmed.aat0882.

PMID:
30651319
3.

Frontiers and Opportunities: Highlights of the 2nd Annual Conference of the Chinese Antibody Society.

Zhang H, Deng M, Lin P, Liu J, Liu C, Strohl WR, Wang S, Ho M.

Antib Ther. 2018 Sep;1(2):65-74. doi: 10.1093/abt/tby009. Epub 2018 Oct 11.

4.

Current progress in innovative engineered antibodies.

Strohl WR.

Protein Cell. 2018 Jan;9(1):86-120. doi: 10.1007/s13238-017-0457-8. Epub 2017 Aug 18. Review.

5.

Adeno-Associated Virus (AAV) as a Vector for Gene Therapy.

Naso MF, Tomkowicz B, Perry WL 3rd, Strohl WR.

BioDrugs. 2017 Aug;31(4):317-334. doi: 10.1007/s40259-017-0234-5. Review.

6.

Antibody-Based Biologics and Their Promise to Combat Staphylococcus aureus Infections.

Sause WE, Buckley PT, Strohl WR, Lynch AS, Torres VJ.

Trends Pharmacol Sci. 2016 Mar;37(3):231-241. doi: 10.1016/j.tips.2015.11.008. Epub 2015 Dec 22. Review.

7.

Fusion Proteins for Half-Life Extension of Biologics as a Strategy to Make Biobetters.

Strohl WR.

BioDrugs. 2015 Aug;29(4):215-39. doi: 10.1007/s40259-015-0133-6. Review.

8.

An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions.

Kinder M, Greenplate AR, Strohl WR, Jordan RE, Brezski RJ.

MAbs. 2015;7(3):494-504. doi: 10.1080/19420862.2015.1022692.

9.

Trastuzumab triggers phagocytic killing of high HER2 cancer cells in vitro and in vivo by interaction with Fcγ receptors on macrophages.

Shi Y, Fan X, Deng H, Brezski RJ, Rycyzyn M, Jordan RE, Strohl WR, Zou Q, Zhang N, An Z.

J Immunol. 2015 May 1;194(9):4379-86. doi: 10.4049/jimmunol.1402891. Epub 2015 Mar 20.

10.

A novel therapeutic strategy to rescue the immune effector function of proteolytically inactivated cancer therapeutic antibodies.

Fan X, Brezski RJ, Deng H, Dhupkar PM, Shi Y, Gonzalez A, Zhang S, Rycyzyn M, Strohl WR, Jordan RE, Zhang N, An Z.

Mol Cancer Ther. 2015 Mar;14(3):681-91. doi: 10.1158/1535-7163.MCT-14-0715. Epub 2014 Dec 31.

11.

Modern therapeutic antibody drug discovery technologies.

Strohl WR.

Curr Drug Discov Technol. 2014 Mar;11(1):1-2. No abstract available.

PMID:
24479659
12.

Antibody discovery: sourcing of monoclonal antibody variable domains.

Strohl WR.

Curr Drug Discov Technol. 2014 Mar;11(1):3-19. Review.

PMID:
24168292
13.

Engineered protease-resistant antibodies with selectable cell-killing functions.

Kinder M, Greenplate AR, Grugan KD, Soring KL, Heeringa KA, McCarthy SG, Bannish G, Perpetua M, Lynch F, Jordan RE, Strohl WR, Brezski RJ.

J Biol Chem. 2013 Oct 25;288(43):30843-54. doi: 10.1074/jbc.M113.486142. Epub 2013 Aug 28.

14.

Potential therapeutic roles for antibody mixtures.

Raju TS, Strohl WR.

Expert Opin Biol Ther. 2013 Oct;13(10):1347-52. doi: 10.1517/14712598.2013.822065. Epub 2013 Jul 26.

PMID:
23886377
15.

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.

Vafa O, Gilliland GL, Brezski RJ, Strake B, Wilkinson T, Lacy ER, Scallon B, Teplyakov A, Malia TJ, Strohl WR.

Methods. 2014 Jan 1;65(1):114-26. doi: 10.1016/j.ymeth.2013.06.035. Epub 2013 Jul 17.

PMID:
23872058
16.

Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1.

Redpath NT, Xu Y, Wilson NJ, Fabri LJ, Baca M, Andrews AE, Braley H, Lu P, Ireland C, Ernst RE, Woods A, Forrest G, An Z, Zaller DM, Strohl WR, Luo CS, Czabotar PE, Garrett TP, Hilton DJ, Nash AD, Zhang JG, Nicola NA.

Biochem J. 2013 Apr 15;451(2):165-75. doi: 10.1042/BJ20121819.

PMID:
23384096
17.

A passion for biotechnology.

Strohl WR.

Hum Vaccin Immunother. 2012 Sep;8(9):1175-8. doi: 10.4161/hv.22150. No abstract available.

18.

Tumor-associated macrophages promote invasion while retaining Fc-dependent anti-tumor function.

Grugan KD, McCabe FL, Kinder M, Greenplate AR, Harman BC, Ekert JE, van Rooijen N, Anderson GM, Nemeth JA, Strohl WR, Jordan RE, Brezski RJ.

J Immunol. 2012 Dec 1;189(11):5457-66. doi: 10.4049/jimmunol.1201889. Epub 2012 Oct 26.

19.

A single proteolytic cleavage within the lower hinge of trastuzumab reduces immune effector function and in vivo efficacy.

Fan X, Brezski RJ, Fa M, Deng H, Oberholtzer A, Gonzalez A, Dubinsky WP, Strohl WR, Jordan RE, Zhang N, An Z.

Breast Cancer Res. 2012 Aug 8;14(4):R116. doi: 10.1186/bcr3240.

20.

Discovery and development of biopharmaceuticals: current issues.

Strohl WR, Knight DM.

Curr Opin Biotechnol. 2009 Dec;20(6):668-72. doi: 10.1016/j.copbio.2009.10.012. Epub 2009 Nov 5. No abstract available.

PMID:
19896824
21.

Optimization of Fc-mediated effector functions of monoclonal antibodies.

Strohl WR.

Curr Opin Biotechnol. 2009 Dec;20(6):685-91. doi: 10.1016/j.copbio.2009.10.011. Epub 2009 Nov 4. Review.

PMID:
19896358
22.

Short communication: In vitro synergy between peptides or neutralizing antibodies targeting the N- and C-terminal heptad repeats of HIV Type 1 gp41.

Hrin R, Montgomery DL, Wang F, Condra JH, An Z, Strohl WR, Bianchi E, Pessi A, Joyce JG, Wang YJ.

AIDS Res Hum Retroviruses. 2008 Dec;24(12):1537-44. doi: 10.1089/aid.2008.0129. Review.

PMID:
19102685
23.

Automated high-throughput purification of antibody fragments to facilitate evaluation in functional and kinetic based assays.

Su B, Hrin R, Harvey BR, Wang YJ, Ernst RE, Hampton RA, Miller MD, Strohl WR, An Z, Montgomery DL.

J Immunol Methods. 2007 Apr 30;322(1-2):94-103. Epub 2007 Mar 7.

PMID:
17362979
24.
25.
26.
27.

Biochemical engineering of natural product biosynthesis pathways.

Strohl WR.

Metab Eng. 2001 Jan;3(1):4-14. Review.

PMID:
11162228
28.

The role of natural products in a modern drug discovery program.

Strohl WR.

Drug Discov Today. 2000 Feb;5(2):39-41. No abstract available.

PMID:
10652450
29.

Nonactin biosynthesis: the potential nonactin biosynthesis gene cluster contains type II polyketide synthase-like genes.

Walczak RJ, Woo AJ, Strohl WR, Priestley ND.

FEMS Microbiol Lett. 2000 Feb 1;183(1):171-5.

30.

Nonactin biosynthesis: the product of nonS catalyzes the formation of the furan ring of nonactic acid.

Woo AJ, Strohl WR, Priestley ND.

Antimicrob Agents Chemother. 1999 Jul;43(7):1662-8.

33.
36.
39.

Thiopeptides.

Strohl WR, Floss HG.

Biotechnology. 1995;28:223-38. Review. No abstract available.

PMID:
8688625
40.

Efficient synthesis of radiolabeled propionyl-coenzyme A and acetyl-coenzyme A.

Rajgarhia VB, Priestley ND, Strohl WR.

Anal Biochem. 1995 Jan 1;224(1):159-62.

PMID:
7710064
41.

Acetate metabolism by Escherichia coli in high-cell-density fermentation.

Kleman GL, Strohl WR.

Appl Environ Microbiol. 1994 Nov;60(11):3952-8.

42.

Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5.

Ye J, Dickens ML, Plater R, Li Y, Lawrence J, Strohl WR.

J Bacteriol. 1994 Oct;176(20):6270-80.

43.

Developments in high cell density and high productivity microbial fermentation.

Kleman GL, Strohl WR.

Curr Opin Biotechnol. 1994 Feb;5(2):180-6. Review.

PMID:
7764797
44.
46.

Purification and characterization of TDP-D-glucose 4,6-dehydratase from anthracycline-producing streptomycetes.

Thompson MW, Strohl WR, Floss HG.

J Gen Microbiol. 1992 Apr;138(4):779-86.

PMID:
1588310
47.

High cell density and high-productivity microbial fermentation.

Kleman GL, Strohl WR.

Curr Opin Biotechnol. 1992 Apr;3(2):93-8. Review.

PMID:
1368292
48.
49.
50.

Transcriptional organization and regulation of the nosiheptide resistance gene in Streptomyces actuosus.

Li Y, Dosch DC, Woodman RH, Floss HG, Strohl WR.

J Ind Microbiol. 1991 Jul;8(1):1-12. Review.

PMID:
1367329

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