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Items: 1 to 50 of 100

1.

The CrowdWater game: A playful way to improve the accuracy of crowdsourced water level class data.

Strobl B, Etter S, van Meerveld I, Seibert J.

PLoS One. 2019 Sep 26;14(9):e0222579. doi: 10.1371/journal.pone.0222579. eCollection 2019.

2.

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade.

Dantoft W, Robertson KA, Watkins WJ, Strobl B, Ghazal P.

Front Microbiol. 2019 Mar 4;10:355. doi: 10.3389/fmicb.2019.00355. eCollection 2019.

3.

Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.

Gawish R, Bulat T, Biaggio M, Lassnig C, Bago-Horvath Z, Macho-Maschler S, Poelzl A, Simonović N, Prchal-Murphy M, Rom R, Amenitsch L, Ferrarese L, Kornhoff J, Lederer T, Svinka J, Eferl R, Bosmann M, Kalinke U, Stoiber D, Sexl V, Krmpotić A, Jonjić S, Müller M, Strobl B.

Cell Rep. 2019 Feb 26;26(9):2394-2406.e5. doi: 10.1016/j.celrep.2019.02.017.

4.

NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity.

Simonović N, Witalisz-Siepracka A, Meissl K, Lassnig C, Reichart U, Kolbe T, Farlik M, Bock C, Sexl V, Müller M, Strobl B.

J Immunol. 2019 Mar 15;202(6):1724-1734. doi: 10.4049/jimmunol.1701649. Epub 2019 Feb 4.

5.

Twins with different personalities: STAT5B-but not STAT5A-has a key role in BCR/ABL-induced leukemia.

Kollmann S, Grundschober E, Maurer B, Warsch W, Grausenburger R, Edlinger L, Huuhtanen J, Lagger S, Hennighausen L, Valent P, Decker T, Strobl B, Mueller M, Mustjoki S, Hoelbl-Kovacic A, Sexl V.

Leukemia. 2019 Jul;33(7):1583-1597. doi: 10.1038/s41375-018-0369-5. Epub 2019 Jan 24.

6.

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment.

Parrini M, Meissl K, Ola MJ, Lederer T, Puga A, Wienerroither S, Kovarik P, Decker T, Müller M, Strobl B.

Front Immunol. 2018 Dec 6;9:2879. doi: 10.3389/fimmu.2018.02879. eCollection 2018.

7.

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

Prutsch N, Gurnhofer E, Suske T, Liang HC, Schlederer M, Roos S, Wu LC, Simonitsch-Klupp I, Alvarez-Hernandez A, Kornauth C, Leone DA, Svinka J, Eferl R, Limberger T, Aufinger A, Shirsath N, Wolf P, Hielscher T, Aberger F, Schmoellerl J, Stoiber D, Strobl B, Jäger U, Staber PB, Grebien F, Moriggl R, Müller M, Inghirami GG, Sanda T, Look AT, Turner SD, Kenner L, Merkel O.

Leukemia. 2019 Mar;33(3):696-709. doi: 10.1038/s41375-018-0239-1. Epub 2018 Aug 21.

PMID:
30131584
8.

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy.

Porpaczy E, Tripolt S, Hoelbl-Kovacic A, Gisslinger B, Bago-Horvath Z, Casanova-Hevia E, Clappier E, Decker T, Fajmann S, Fux DA, Greiner G, Gueltekin S, Heller G, Herkner H, Hoermann G, Kiladjian JJ, Kolbe T, Kornauth C, Krauth MT, Kralovics R, Muellauer L, Mueller M, Prchal-Murphy M, Putz EM, Raffoux E, Schiefer AI, Schmetterer K, Schneckenleithner C, Simonitsch-Klupp I, Skrabs C, Sperr WR, Staber PB, Strobl B, Valent P, Jaeger U, Gisslinger H, Sexl V.

Blood. 2018 Aug 16;132(7):694-706. doi: 10.1182/blood-2017-10-810739. Epub 2018 Jun 14. Erratum in: Blood. 2019 Feb 14;133(7):768.

PMID:
29907599
9.

STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.

Crnčec I, Modak M, Gordziel C, Svinka J, Scharf I, Moritsch S, Pathria P, Schlederer M, Kenner L, Timelthaler G, Müller M, Strobl B, Casanova E, Bayer E, Mohr T, Stöckl J, Friedrich K, Eferl R.

Mol Oncol. 2018 Apr;12(4):514-528. doi: 10.1002/1878-0261.12178. Epub 2018 Feb 20.

10.

Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells.

Raje V, Derecka M, Cantwell M, Meier J, Szczepanek K, Sisler JD, Strobl B, Gamero A, Harris TE, Larner AC.

Endocrinology. 2017 Jan 1;158(1):148-157. doi: 10.1210/en.2015-2048.

11.

Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice.

Maier BB, Hladik A, Lakovits K, Korosec A, Martins R, Kral JB, Mesteri I, Strobl B, Müller M, Kalinke U, Merad M, Knapp S.

Eur J Immunol. 2016 Sep;46(9):2175-86. doi: 10.1002/eji.201546201. Epub 2016 Jul 12.

12.

Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases.

Floss DM, Klöcker T, Schröder J, Lamertz L, Mrotzek S, Strobl B, Hermanns H, Scheller J.

Mol Biol Cell. 2016 Jul 15;27(14):2301-16. doi: 10.1091/mbc.E14-12-1645. Epub 2016 May 18.

13.

Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue.

Castiglia V, Piersigilli A, Ebner F, Janos M, Goldmann O, Damböck U, Kröger A, Weiss S, Knapp S, Jamieson AM, Kirschning C, Kalinke U, Strobl B, Müller M, Stoiber D, Lienenklaus S, Kovarik P.

Cell Host Microbe. 2016 Mar 9;19(3):375-87. doi: 10.1016/j.chom.2016.02.003.

14.

STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion.

Gotthardt D, Putz EM, Grundschober E, Prchal-Murphy M, Straka E, Kudweis P, Heller G, Bago-Horvath Z, Witalisz-Siepracka A, Cumaraswamy AA, Gunning PT, Strobl B, Müller M, Moriggl R, Stockmann C, Sexl V.

Cancer Discov. 2016 Apr;6(4):414-29. doi: 10.1158/2159-8290.CD-15-0732. Epub 2016 Feb 12.

15.

Intestinal Microbiota Signatures Associated with Inflammation History in Mice Experiencing Recurring Colitis.

Berry D, Kuzyk O, Rauch I, Heider S, Schwab C, Hainzl E, Decker T, Müller M, Strobl B, Schleper C, Urich T, Wagner M, Kenner L, Loy A.

Front Microbiol. 2015 Dec 15;6:1408. doi: 10.3389/fmicb.2015.01408. eCollection 2015.

16.

The good and the bad faces of STAT1 in solid tumours.

Meissl K, Macho-Maschler S, Müller M, Strobl B.

Cytokine. 2017 Jan;89:12-20. doi: 10.1016/j.cyto.2015.11.011. Epub 2015 Nov 26. Review.

17.

Tyrosine kinase 2 - Surveillant of tumours and bona fide oncogene.

Leitner NR, Witalisz-Siepracka A, Strobl B, Müller M.

Cytokine. 2017 Jan;89:209-218. doi: 10.1016/j.cyto.2015.10.015. Epub 2015 Nov 26. Review.

18.

In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity.

Prchal-Murphy M, Witalisz-Siepracka A, Bednarik KT, Putz EM, Gotthardt D, Meissl K, Sexl V, Müller M, Strobl B.

Oncoimmunology. 2015 May 26;4(11):e1047579. eCollection 2015 Nov.

19.

Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis.

Hainzl E, Stockinger S, Rauch I, Heider S, Berry D, Lassnig C, Schwab C, Rosebrock F, Milinovich G, Schlederer M, Wagner M, Schleper C, Loy A, Urich T, Kenner L, Han X, Decker T, Strobl B, Müller M.

J Immunol. 2015 Nov 15;195(10):5011-24. doi: 10.4049/jimmunol.1402565. Epub 2015 Oct 2.

20.

Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex.

Wienerroither S, Shukla P, Farlik M, Majoros A, Stych B, Vogl C, Cheon H, Stark GR, Strobl B, Müller M, Decker T.

Cell Rep. 2015 Jul 14;12(2):300-12. doi: 10.1016/j.celrep.2015.06.021. Epub 2015 Jul 2.

21.

Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice.

Pathria P, Gotthardt D, Prchal-Murphy M, Putz EM, Holcmann M, Schlederer M, Grabner B, Crncec I, Svinka J, Musteanu M, Hoffmann T, Filipits M, Berger W, Poli V, Kenner L, Bilban M, Casanova E, Müller M, Strobl B, Bayer E, Mohr T, Sexl V, Eferl R.

Oncoimmunology. 2015 Jan 22;4(4):e998529. eCollection 2015 Apr.

22.

Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons.

Rauch I, Rosebrock F, Hainzl E, Heider S, Majoros A, Wienerroither S, Strobl B, Stockinger S, Kenner L, Müller M, Decker T.

Mol Cell Biol. 2015 Jul;35(13):2332-43. doi: 10.1128/MCB.01498-14. Epub 2015 Apr 27.

23.

Methods to study tumor surveillance using tumor cell transplantation into genetically engineered mice.

Bauer E, Witalisz A, Strobl B, Stoiber D.

Methods Mol Biol. 2015;1267:439-56. doi: 10.1007/978-1-4939-2297-0_22.

PMID:
25636483
24.

Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription.

Wiesauer I, Gaumannmüller C, Steinparzer I, Strobl B, Kovarik P.

Mol Cell Biol. 2015 Feb;35(4):716-27. doi: 10.1128/MCB.01097-14. Epub 2014 Dec 15.

25.

Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.

Bosmann M, Russkamp NF, Strobl B, Roewe J, Balouzian L, Pache F, Radsak MP, van Rooijen N, Zetoune FS, Sarma JV, Núñez G, Müller M, Murray PJ, Ward PA.

J Immunol. 2014 Dec 1;193(11):5668-77. doi: 10.4049/jimmunol.1302280. Epub 2014 Oct 27.

26.

Loss of STAT3 in murine NK cells enhances NK cell-dependent tumor surveillance.

Gotthardt D, Putz EM, Straka E, Kudweis P, Biaggio M, Poli V, Strobl B, Müller M, Sexl V.

Blood. 2014 Oct 9;124(15):2370-9. doi: 10.1182/blood-2014-03-564450. Epub 2014 Sep 2.

27.

Type I interferons have opposing effects during the emergence and recovery phases of colitis.

Rauch I, Hainzl E, Rosebrock F, Heider S, Schwab C, Berry D, Stoiber D, Wagner M, Schleper C, Loy A, Urich T, Müller M, Strobl B, Kenner L, Decker T.

Eur J Immunol. 2014 Sep;44(9):2749-60. doi: 10.1002/eji.201344401. Epub 2014 Aug 25.

28.

Recovery from chemotherapy depends on STAT1 for replenishment of B lymphopoiesis.

Strobl B, Moriggl R.

J Leukoc Biol. 2014 Jun;95(6):849-51. doi: 10.1189/jlb.0114051. No abstract available.

PMID:
24891311
29.

STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.

Semper C, Leitner NR, Lassnig C, Parrini M, Mahlakõiv T, Rammerstorfer M, Lorenz K, Rigler D, Müller S, Kolbe T, Vogl C, Rülicke T, Staeheli P, Decker T, Müller M, Strobl B.

Mol Cell Biol. 2014 Jun;34(12):2235-48. doi: 10.1128/MCB.00295-14. Epub 2014 Apr 7.

30.

Conditional ablation of TYK2 in immunity to viral infection and tumor surveillance.

Vielnascher RM, Hainzl E, Leitner NR, Rammerstorfer M, Popp D, Witalisz A, Rom R, Karaghiosoff M, Kolbe T, Müller S, Rülicke T, Lassnig C, Strobl B, Müller M.

Transgenic Res. 2014 Jun;23(3):519-29. doi: 10.1007/s11248-014-9795-y. Epub 2014 Apr 3.

PMID:
24696087
31.

Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27.

Bosmann M, Strobl B, Kichler N, Rigler D, Grailer JJ, Pache F, Murray PJ, Müller M, Ward PA.

J Leukoc Biol. 2014 Jul;96(1):123-31. doi: 10.1189/jlb.3A1013-541R. Epub 2014 Mar 6.

32.

Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo.

Leitner NR, Lassnig C, Rom R, Heider S, Bago-Horvath Z, Eferl R, Müller S, Kolbe T, Kenner L, Rülicke T, Strobl B, Müller M.

PLoS One. 2014 Jan 29;9(1):e86608. doi: 10.1371/journal.pone.0086608. eCollection 2014.

33.

Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery.

Schwab C, Berry D, Rauch I, Rennisch I, Ramesmayer J, Hainzl E, Heider S, Decker T, Kenner L, Müller M, Strobl B, Wagner M, Schleper C, Loy A, Urich T.

ISME J. 2014 May;8(5):1101-14. doi: 10.1038/ismej.2013.223. Epub 2014 Jan 9.

34.

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.

Liehl P, Zuzarte-Luís V, Chan J, Zillinger T, Baptista F, Carapau D, Konert M, Hanson KK, Carret C, Lassnig C, Müller M, Kalinke U, Saeed M, Chora AF, Golenbock DT, Strobl B, Prudêncio M, Coelho LP, Kappe SH, Superti-Furga G, Pichlmair A, Vigário AM, Rice CM, Fitzgerald KA, Barchet W, Mota MM.

Nat Med. 2014 Jan;20(1):47-53. doi: 10.1038/nm.3424. Epub 2013 Dec 22.

35.

Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation.

Keil E, Finkenstädt D, Wufka C, Trilling M, Liebfried P, Strobl B, Müller M, Pfeffer K.

Blood. 2014 Jan 23;123(4):520-9. doi: 10.1182/blood-2013-03-492157. Epub 2013 Oct 29.

PMID:
24169825
36.

A case report that suggested that aspirin's effects on valproic acid metabolism may contribute to valproic acid's inducer effects on clozapine metabolism.

Riesselman A, Strobl B, Cooley AT, de Leon J.

J Clin Psychopharmacol. 2013 Dec;33(6):812-4. doi: 10.1097/JCP.0b013e3182a4ea8f. No abstract available.

PMID:
24113673
37.

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes.

Warszawska JM, Gawish R, Sharif O, Sigel S, Doninger B, Lakovits K, Mesteri I, Nairz M, Boon L, Spiel A, Fuhrmann V, Strobl B, Müller M, Schenk P, Weiss G, Knapp S.

J Clin Invest. 2013 Aug;123(8):3363-72. doi: 10.1172/JCI67911. Epub 2013 Jul 1.

38.

CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.

Bancerek J, Poss ZC, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dölken L, Strobl B, Müller M, Taatjes DJ, Kovarik P.

Immunity. 2013 Feb 21;38(2):250-62. doi: 10.1016/j.immuni.2012.10.017. Epub 2013 Jan 24.

39.

Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity.

Derecka M, Gornicka A, Koralov SB, Szczepanek K, Morgan M, Raje V, Sisler J, Zhang Q, Otero D, Cichy J, Rajewsky K, Shimoda K, Poli V, Strobl B, Pellegrini S, Harris TE, Seale P, Russell AP, McAinch AJ, O'Brien PE, Keller SR, Croniger CM, Kordula T, Larner AC.

Cell Metab. 2012 Dec 5;16(6):814-24. doi: 10.1016/j.cmet.2012.11.005.

40.

Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance.

Mizutani T, Neugebauer N, Putz EM, Moritz N, Simma O, Zebedin-Brandl E, Gotthardt D, Warsch W, Eckelhart E, Kantner HP, Kalinke U, Lienenklaus S, Weiss S, Strobl B, Müller M, Sexl V, Stoiber D.

Oncoimmunology. 2012 Oct 1;1(7):1027-1037.

41.

TYK2 kinase activity is required for functional type I interferon responses in vivo.

Prchal-Murphy M, Semper C, Lassnig C, Wallner B, Gausterer C, Teppner-Klymiuk I, Kobolak J, Müller S, Kolbe T, Karaghiosoff M, Dinnyés A, Rülicke T, Leitner NR, Strobl B, Müller M.

PLoS One. 2012;7(6):e39141. doi: 10.1371/journal.pone.0039141. Epub 2012 Jun 18.

42.

Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection.

Kernbauer E, Maier V, Stoiber D, Strobl B, Schneckenleithner C, Sexl V, Reichart U, Reizis B, Kalinke U, Jamieson A, Müller M, Decker T.

PLoS Pathog. 2012;8(6):e1002763. doi: 10.1371/journal.ppat.1002763. Epub 2012 Jun 14.

43.

Phylotype-level 16S rRNA analysis reveals new bacterial indicators of health state in acute murine colitis.

Berry D, Schwab C, Milinovich G, Reichert J, Ben Mahfoudh K, Decker T, Engel M, Hai B, Hainzl E, Heider S, Kenner L, Müller M, Rauch I, Strobl B, Wagner M, Schleper C, Urich T, Loy A.

ISME J. 2012 Nov;6(11):2091-106. doi: 10.1038/ismej.2012.39. Epub 2012 May 10.

44.

A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C).

Grunert T, Leitner NR, Marchetti-Deschmann M, Miller I, Wallner B, Radwan M, Vogl C, Kolbe T, Kratky D, Gemeiner M, Allmaier G, Müller M, Strobl B.

J Proteomics. 2011 Nov 18;74(12):2866-80. doi: 10.1016/j.jprot.2011.07.006. Epub 2011 Jul 23.

45.

Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.

Kropp KA, Robertson KA, Sing G, Rodriguez-Martin S, Blanc M, Lacaze P, Hassim MF, Khondoker MR, Busche A, Dickinson P, Forster T, Strobl B, Mueller M, Jonjic S, Angulo A, Ghazal P.

J Virol. 2011 Oct;85(19):10286-99. doi: 10.1128/JVI.00373-11. Epub 2011 Jul 20.

46.

Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity.

Strobl B, Stoiber D, Sexl V, Mueller M.

Front Biosci (Landmark Ed). 2011 Jun 1;16:3214-32. Review.

PMID:
21622231
47.

Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis.

Todoric J, Strobl B, Jais A, Boucheron N, Bayer M, Amann S, Lindroos J, Teperino R, Prager G, Bilban M, Ellmeier W, Krempler F, Müller M, Wagner O, Patsch W, Pospisilik JA, Esterbauer H.

Diabetes. 2011 Jun;60(6):1668-76. doi: 10.2337/db10-1628. Epub 2011 May 2.

48.

Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.

Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, Khondoker M, Dickinson P, Sing G, Rodríguez-Martín S, Phelan P, Forster T, Strobl B, Müller M, Riemersma R, Osborne T, Wenk MR, Angulo A, Ghazal P.

PLoS Biol. 2011 Mar;9(3):e1000598. doi: 10.1371/journal.pbio.1000598. Epub 2011 Mar 8.

49.

Tyrosine kinase 2 controls IL-1ß production at the translational level.

Radwan M, Stiefvater R, Grunert T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Müller M, Strobl B.

J Immunol. 2010 Sep 15;185(6):3544-53. doi: 10.4049/jimmunol.0904000. Epub 2010 Aug 16.

50.

Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses.

Hofmann E, Reichart U, Gausterer C, Guelly C, Meijer D, Müller M, Strobl B.

BMC Cell Biol. 2010 Aug 5;11:61. doi: 10.1186/1471-2121-11-61.

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