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Items: 1 to 50 of 150

1.

Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients.

Zhao XY, Li J, Wang JH, Habib S, Wei W, Sun SJ, Strobel HW, Jia JD.

Medicine (Baltimore). 2016 Jul;95(27):e3926. doi: 10.1097/MD.0000000000003926.

2.

Evaluating educators using a novel toolbox: applying rigorous criteria flexibly across institutions.

Gusic ME, Baldwin CD, Chandran L, Rose S, Simpson D, Strobel HW, Timm C, Fincher RM.

Acad Med. 2014 Jul;89(7):1006-11. doi: 10.1097/ACM.0000000000000233.

3.

Cytochrome P450-mediated metabolism in brain: functional roles and their implications.

Ravindranath V, Strobel HW.

Expert Opin Drug Metab Toxicol. 2013 May;9(5):551-8. doi: 10.1517/17425255.2013.759208. Epub 2013 Jan 18. Review.

PMID:
23330950
4.

Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury.

Dulin JN, Karoly ED, Wang Y, Strobel HW, Grill RJ.

J Neurosci. 2013 Jan 9;33(2):652-64. doi: 10.1523/JNEUROSCI.6128-11.2013.

5.

Regulation of cytochrome P450 4F11 by nuclear transcription factor-κB.

Bell JC, Strobel HW.

Drug Metab Dispos. 2012 Jan;40(1):205-11. doi: 10.1124/dmd.111.041178. Epub 2011 Oct 19.

6.

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

Sehgal N, Agarwal V, Valli RK, Joshi SD, Antonovic L, Strobel HW, Ravindranath V.

Biochem Pharmacol. 2011 Jul 1;82(1):53-64. doi: 10.1016/j.bcp.2011.03.025. Epub 2011 Apr 2.

PMID:
21466787
7.

Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.

Wang Y, Bell JC, Keeney DS, Strobel HW.

Drug Metab Dispos. 2010 Jan;38(1):100-7. doi: 10.1124/dmd.109.029025.

8.

20-Hydroxylation is the CYP-dependent and retinoid-inducible leukotriene B4 inactivation pathway in human and mouse skin cells.

Du L, Yin H, Morrow JD, Strobel HW, Keeney DS.

Arch Biochem Biophys. 2009 Apr 1;484(1):80-6. doi: 10.1016/j.abb.2009.01.012. Epub 2009 Jan 20.

9.

Regulation of hepatic cytochrome P450 expression in mice with intestinal or systemic infections of citrobacter rodentium.

Chaluvadi MR, Kinloch RD, Nyagode BA, Richardson TA, Raynor MJ, Sherman M, Antonovic L, Strobel HW, Dillehay DL, Morgan ET.

Drug Metab Dispos. 2009 Feb;37(2):366-74. doi: 10.1124/dmd.108.024240. Epub 2008 Oct 29.

10.

CYP4Fs expression in rat brain correlates with changes in LTB4 levels after traumatic brain injury.

Wang Y, Zhao J, Kalsotra A, Turman CM, Grill RJ, Dash PK, Strobel HW.

J Neurotrauma. 2008 Oct;25(10):1187-94. doi: 10.1089/neu.2008.0542.

11.

Drug metabolism in human brain: high levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metabolite.

Agarwal V, Kommaddi RP, Valli K, Ryder D, Hyde TM, Kleinman JE, Strobel HW, Ravindranath V.

PLoS One. 2008 Jun 11;3(6):e2337. doi: 10.1371/journal.pone.0002337.

12.

Expression and physiological function of CYP4F subfamily in human eosinophils.

Kikuta Y, Mizomoto J, Strobel HW, Ohkawa H.

Biochim Biophys Acta. 2007 Dec;1771(12):1439-45. Epub 2007 Oct 16.

PMID:
17980168
13.

Inflammation resolved by retinoid X receptor-mediated inactivation of leukotriene signaling pathways.

Kalsotra A, Du L, Wang Y, Ladd PA, Kikuta Y, Duvic M, Boyd AS, Keeney DS, Strobel HW.

FASEB J. 2008 Feb;22(2):538-47. Epub 2007 Sep 20.

PMID:
17884973
14.

An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites.

Kommaddi RP, Turman CM, Moorthy B, Wang L, Strobel HW, Ravindranath V.

J Neurochem. 2007 Aug;102(3):867-77.

15.

The chimpanzee cytochrome P450 3A subfamily: Is our closest related species really that similar?

Williams ET, Schouest KR, Leyk M, Strobel HW.

Comp Biochem Physiol Part D Genomics Proteomics. 2007 Jun;2(2):91-100. doi: 10.1016/j.cbd.2006.12.004. Epub 2007 Jan 26.

PMID:
20483282
16.

Catalytic characterization and cytokine mediated regulation of cytochrome P450 4Fs in rat hepatocytes.

Kalsotra A, Anakk S, Brommer CL, Kikuta Y, Morgan ET, Strobel HW.

Arch Biochem Biophys. 2007 May 1;461(1):104-12. Epub 2007 Mar 15.

17.

Gender dictates the nuclear receptor-mediated regulation of CYP3A44.

Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW.

Drug Metab Dispos. 2007 Jan;35(1):36-42. Epub 2006 Oct 4.

PMID:
17020958
18.

Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution.

Kalsotra A, Zhao J, Anakk S, Dash PK, Strobel HW.

J Cereb Blood Flow Metab. 2007 May;27(5):963-74. Epub 2006 Sep 20.

PMID:
16985506
19.

Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism.

Kalsotra A, Strobel HW.

Pharmacol Ther. 2006 Dec;112(3):589-611. Epub 2006 Aug 22. Review.

PMID:
16926051
20.

Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: The convolution continues.

Turman CM, Hatley JM, Ryder DJ, Ravindranath V, Strobel HW.

Expert Opin Drug Metab Toxicol. 2006 Jun;2(3):399-418. Review.

PMID:
16863442
21.

Hepatic and renal cytochrome p450 gene regulation during citrobacter rodentium infection in wild-type and toll-like receptor 4 mutant mice.

Richardson TA, Sherman M, Antonovic L, Kardar SS, Strobel HW, Kalman D, Morgan ET.

Drug Metab Dispos. 2006 Mar;34(3):354-60. Epub 2005 Dec 8.

22.

Renal localization, expression, and developmental regulation of P450 4F cytochromes in three substrains of spontaneously hypertensive rats.

Kalsotra A, Cui X, Anakk S, Hinojos CA, Doris PA, Strobel HW.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):423-31. Epub 2005 Aug 25.

PMID:
16182239
23.

Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain.

Chinta SJ, Kommaddi RP, Turman CM, Strobel HW, Ravindranath V.

J Neurochem. 2005 May;93(3):724-36.

24.

Evaluation of comparative cytochrome P450 2B4 model by photoaffinity labeling.

Hodek P, Sopko B, Antonovic L, Sulc M, Novák P, Strobel HW.

Gen Physiol Biophys. 2004 Dec;23(4):467-88.

25.

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

Kalsotra A, Turman CM, Kikuta Y, Strobel HW.

Toxicol Appl Pharmacol. 2004 Sep 15;199(3):295-304.

PMID:
15364545
26.
27.

Estrogen regulation of the cytochrome P450 3A subfamily in humans.

Williams ET, Leyk M, Wrighton SA, Davies PJ, Loose DS, Shipley GL, Strobel HW.

J Pharmacol Exp Ther. 2004 Nov;311(2):728-35. Epub 2004 Jul 28.

PMID:
15282264
28.

CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.

Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW.

Pharmacogenomics J. 2004;4(2):91-101.

PMID:
14770174
29.

Differential effects of traumatic brain injury on the cytochrome p450 system: a perspective into hepatic and renal drug metabolism.

Kalsotra A, Turman CM, Dash PK, Strobel HW.

J Neurotrauma. 2003 Dec;20(12):1339-50.

PMID:
14748982
30.
31.

Inflammatory prompts produce isoform-specific changes in the expression of leukotriene B(4) omega-hydroxylases in rat liver and kidney.

Kalsotra A, Cui X, Antonovic L, Robida AM, Morgan ET, Strobel HW.

FEBS Lett. 2003 Dec 4;555(2):236-42.

32.

Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.

Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW.

FASEB J. 2003 Sep;17(12):1736-8. Epub 2003 Jul 3.

PMID:
12958193
33.

Insights into gender bias: rat cytochrome P450 3A9.

Anakk S, Ku CY, Vore M, Strobel HW.

J Pharmacol Exp Ther. 2003 May;305(2):703-9. Epub 2003 Feb 11.

PMID:
12606633
34.

Expression of cytochromes P450 4F4 and 4F5 in infection and injury models of inflammation.

Cui X, Kalsotra A, Robida AM, Matzilevich D, Moore AN, Boehme CL, Morgan ET, Dash PK, Strobel HW.

Biochim Biophys Acta. 2003 Feb 17;1619(3):325-31.

PMID:
12573492
35.

Cloning and characterization of the rat cytochrome P450 4F5 (CYP4F5) gene.

Cui X, Strobel HW.

Gene. 2002 Sep 4;297(1-2):179-87.

PMID:
12384299
36.

Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats.

Kalsotra A, Anakk S, Boehme CL, Strobel HW.

Drug Metab Dispos. 2002 Sep;30(9):1022-8.

PMID:
12167568
37.

Bringing a family practice model of health to the People's Republic of China.

Nieman LZ, Kvale PJ, Fu X, Gu Y, Strobel HW.

Fam Med. 2001 Oct;33(9):696-701. Review.

PMID:
11665909
38.

Cytochromes P450 in brain: function and significance.

Strobel HW, Thompson CM, Antonovic L.

Curr Drug Metab. 2001 Jun;2(2):199-214. Review.

PMID:
11469726
39.

Role of THR501 residue in substrate binding and catalytic activity of cytochrome P4501A1.

Cvrk T, Strobel HW.

Arch Biochem Biophys. 2001 May 1;389(1):31-40.

PMID:
11370669
40.
41.
42.

Cytochrome P450 3A9 catalyzes the metabolism of progesterone and other steroid hormones.

Wang H, Napoli KL, Strobel HW.

Mol Cell Biochem. 2000 Oct;213(1-2):127-35.

PMID:
11129951
43.

Chronic intragastric infusion of ethanol-containing diets induces CYP3A9 while decreasing CYP3A2 in male rats.

Rowlands JC, Wang H, Hakkak R, Ronis MJ, Strobel HW, Badger TM.

J Pharmacol Exp Ther. 2000 Nov;295(2):747-52.

PMID:
11046114
44.
45.

Recombinant cytochrome P450 2D18 metabolism of dopamine and arachidonic acid.

Thompson CM, Capdevila JH, Strobel HW.

J Pharmacol Exp Ther. 2000 Sep;294(3):1120-30.

PMID:
10945868
46.

Metabolism of cyclosporine by cytochromes P450 3A9 and 3A4.

Kelly PA, Wang H, Napoli KL, Kahan BD, Strobel HW.

Eur J Drug Metab Pharmacokinet. 1999 Oct-Dec;24(4):321-8.

PMID:
10892895
47.

Cytochrome P-450 activities in human and rat brain microsomes.

Voirol P, Jonzier-Perey M, Porchet F, Reymond MJ, Janzer RC, Bouras C, Strobel HW, Kosel M, Eap CB, Baumann P.

Brain Res. 2000 Feb 14;855(2):235-43.

PMID:
10677595
48.

Heterobifunctional photoaffinity probes for cytochrome P450 2B.

Antonovic L, Hodek P, Smrcek S, Novák P, Sulc M, Strobel HW.

Arch Biochem Biophys. 1999 Oct 15;370(2):208-15.

PMID:
10510279
49.

Extrahepatic drug metabolizing enzymes.

Kapitulnik J, Strobel HW.

J Biochem Mol Toxicol. 1999;13(5):227-30. Review.

PMID:
10402555
50.

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