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Items: 1 to 50 of 59

1.

In vivo generation of human CD19-CAR T cells results in B-cell depletion and signs of cytokine release syndrome.

Pfeiffer A, Thalheimer FB, Hartmann S, Frank AM, Bender RR, Danisch S, Costa C, Wels WS, Modlich U, Stripecke R, Verhoeyen E, Buchholz CJ.

EMBO Mol Med. 2018 Sep 17. pii: e9158. doi: 10.15252/emmm.201809158. [Epub ahead of print]

2.

Multidimensional Analysis Integrating Human T-Cell Signatures in Lymphatic Tissues with Sex of Humanized Mice for Prediction of Responses after Dendritic Cell Immunization.

Volk V, Reppas AI, Robert PA, Spineli LM, Sundarasetty BS, Theobald SJ, Schneider A, Gerasch L, Deves Roth C, Klöss S, Koehl U, von Kaisenberg C, Figueiredo C, Hatzikirou H, Meyer-Hermann M, Stripecke R.

Front Immunol. 2017 Dec 8;8:1709. doi: 10.3389/fimmu.2017.01709. eCollection 2017.

3.

Reconstructing the immune system with lentiviral vectors.

Olbrich H, Slabik C, Stripecke R.

Virus Genes. 2017 Oct;53(5):723-732. doi: 10.1007/s11262-017-1495-2. Epub 2017 Jul 25. Review.

4.

Human Effector Memory T Helper Cells Engage with Mouse Macrophages and Cause Graft-versus-Host-Like Pathology in Skin of Humanized Mice Used in a Nonclinical Immunization Study.

Sundarasetty B, Volk V, Theobald SJ, Rittinghausen S, Schaudien D, Neuhaus V, Figueiredo C, Schneider A, Gerasch L, Mucci A, Moritz T, von Kaisenberg C, Spineli LM, Sewald K, Braun A, Weigt H, Ganser A, Stripecke R.

Am J Pathol. 2017 Jun;187(6):1380-1398. doi: 10.1016/j.ajpath.2017.02.015. Epub 2017 Apr 20.

PMID:
28432872
5.

Na+ /H+ exchanger NHE1 and NHE2 have opposite effects on migration velocity in rat gastric surface cells.

Paehler Vor der Nolte A, Chodisetti G, Yuan Z, Busch F, Riederer B, Luo M, Yu Y, Menon MB, Schneider A, Stripecke R, Nikolovska K, Yeruva S, Seidler U.

J Cell Physiol. 2017 Jul;232(7):1669-1680. doi: 10.1002/jcp.25758. Epub 2017 Feb 21.

6.

Leukemias and bones: humanizing the niche in mice.

Stripecke R.

Blood. 2016 Dec 22;128(25):2874-2875. doi: 10.1182/blood-2016-11-746867. No abstract available.

7.

Dendritic-tumor cell hybrids induce tumor-specific immune responses more effectively than the simple mixture of dendritic and tumor cells.

Pinho MP, Sundarasetty BS, Bergami-Santos PC, Steponavicius-Cruz K, Ferreira AK, Stripecke R, Barbuto JA.

Cytotherapy. 2016 Apr;18(4):570-80. doi: 10.1016/j.jcyt.2016.01.005.

PMID:
26971685
8.

TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads.

Low HZ, Ahrenstorf G, Pommerenke C, Habermann N, Schughart K, Ordóñez D, Stripecke R, Wilk E, Witte T.

Retrovirology. 2016 Mar 12;13:15. doi: 10.1186/s12977-016-0248-y.

9.

The gender gap: discrepant human T-cell reconstitution after cord blood stem cell transplantation in humanized female and male mice.

Volk V, Schneider A, Spineli LM, Grosshennig A, Stripecke R.

Bone Marrow Transplant. 2016 Apr;51(4):596-7. doi: 10.1038/bmt.2015.290. Epub 2015 Nov 23. No abstract available.

10.

Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation.

Sundarasetty BS, Kloess S, Oberschmidt O, Naundorf S, Kuehlcke K, Daenthanasanmak A, Gerasch L, Figueiredo C, Blasczyk R, Ruggiero E, Fronza R, Schmidt M, von Kalle C, Rothe M, Ganser A, Koehl U, Stripecke R.

J Transl Med. 2015 Jul 22;13:240. doi: 10.1186/s12967-015-0599-5.

11.

Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV.

Daenthanasanmak A, Salguero G, Sundarasetty BS, Waskow C, Cosgun KN, Guzman CA, Riese P, Gerasch L, Schneider A, Ingendoh A, Messerle M, Gabaev I, Woelk B, Ruggiero E, Schmidt M, von Kalle C, Figueiredo C, Eiz-Vesper B, von Kaisenberg C, Ganser A, Stripecke R.

Mol Ther Methods Clin Dev. 2015 Jan 7;1:14060. doi: 10.1038/mtm.2014.60. eCollection 2015.

12.

Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma.

Sundarasetty BS, Chan L, Darling D, Giunti G, Farzaneh F, Schenck F, Naundorf S, Kuehlcke K, Ruggiero E, Schmidt M, von Kalle C, Rothe M, Hoon DS, Gerasch L, Figueiredo C, Koehl U, Blasczyk R, Gutzmer R, Stripecke R.

Gene Ther. 2015 Sep;22(9):707-20. doi: 10.1038/gt.2015.43. Epub 2015 May 28.

13.

Lentivirus-Induced Dendritic Cells (iDC) for Immune-Regenerative Therapies in Cancer and Stem Cell Transplantation.

Stripecke R.

Biomedicines. 2014 Aug 21;2(3):229-246. doi: 10.3390/biomedicines2030229. Review.

14.

Evaluation of suitable target antigens and immunoassays for high-accuracy immune monitoring of cytomegalovirus and Epstein-Barr virus-specific T cells as targets of interest in immunotherapeutic approaches.

Tischer S, Dieks D, Sukdolak C, Bunse C, Figueiredo C, Immenschuh S, Borchers S, Stripecke R, Maecker-Kolhoff B, Blasczyk R, Eiz-Vesper B.

J Immunol Methods. 2014 Jun;408:101-13. doi: 10.1016/j.jim.2014.05.011. Epub 2014 May 28.

PMID:
24877879
15.

Dendritic cell-mediated immune humanization of mice: implications for allogeneic and xenogeneic stem cell transplantation.

Salguero G, Daenthanasanmak A, Münz C, Raykova A, Guzmán CA, Riese P, Figueiredo C, Länger F, Schneider A, Macke L, Sundarasetty BS, Witte T, Ganser A, Stripecke R.

J Immunol. 2014 May 15;192(10):4636-47. doi: 10.4049/jimmunol.1302887. Epub 2014 Apr 16.

16.

Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits.

Schlahsa L, Zhang H, Battermann A, Verboom M, Immenschuh S, Eiz-Vesper B, Stripecke R, Engelmann K, Blasczyk R, Figueiredo C.

Transfusion. 2014 Aug;54(8):1961-70. doi: 10.1111/trf.12631. Epub 2014 Mar 28.

PMID:
24673430
17.

Association of the LILRA3 deletion with B-NHL and functional characterization of the immunostimulatory molecule.

Low HZ, Reuter S, Topperwien M, Dankenbrink N, Peest D, Kabalak G, Stripecke R, Schmidt RE, Matthias T, Witte T.

PLoS One. 2013 Dec 9;8(12):e81360. doi: 10.1371/journal.pone.0081360. eCollection 2013.

18.

Monitoring dendritic cell and cytokine biomarkers during remission prior to relapse in patients with FLT3-ITD acute myeloid leukemia.

Rickmann M, Macke L, Sundarasetty BS, Stamer K, Figueiredo C, Blasczyk R, Heuser M, Krauter J, Ganser A, Stripecke R.

Ann Hematol. 2013 Aug;92(8):1079-90. doi: 10.1007/s00277-013-1744-y. Epub 2013 Apr 25.

19.

The innovative evolution of cancer gene and cellular therapies.

Lam P, Khan G, Stripecke R, Hui KM, Kasahara N, Peng KW, Guinn BA.

Cancer Gene Ther. 2013 Mar;20(3):141-9. doi: 10.1038/cgt.2012.93. Epub 2013 Feb 1. Review.

PMID:
23370333
20.

Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia.

Sundarasetty BS, Singh VK, Salguero G, Geffers R, Rickmann M, Macke L, Borchers S, Figueiredo C, Schambach A, Gullberg U, Provasi E, Bonini C, Ganser A, Woelfel T, Stripecke R.

Hum Gene Ther. 2013 Feb;24(2):220-37. doi: 10.1089/hum.2012.128.

21.

Selection for Evi1 activation in myelomonocytic leukemia induced by hyperactive signaling through wild-type NRas.

Wolf S, Rudolph C, Morgan M, Büsche G, Salguero G, Stripecke R, Schlegelberger B, Baum C, Modlich U.

Oncogene. 2013 Jun 20;32(25):3028-38. doi: 10.1038/onc.2012.329. Epub 2012 Jul 30.

PMID:
22847614
22.

Integrase-defective lentiviral vectors encoding cytokines induce differentiation of human dendritic cells and stimulate multivalent immune responses in vitro and in vivo.

Daenthanasanmak A, Salguero G, Borchers S, Figueiredo C, Jacobs R, Sundarasetty BS, Schneider A, Schambach A, Eiz-Vesper B, Blasczyk R, Weissinger EM, Ganser A, Stripecke R.

Vaccine. 2012 Jul 20;30(34):5118-31. doi: 10.1016/j.vaccine.2012.05.063. Epub 2012 Jun 9.

23.

Identity, potency, in vivo viability, and scaling up production of lentiviral vector-induced dendritic cells for melanoma immunotherapy.

Pincha M, Sundarasetty BS, Salguero G, Gutzmer R, Garritsen H, Macke L, Schneider A, Lenz D, Figueiredo C, Blasczyk R, Ruggiero E, Schmidt M, von Kalle C, Puff C, Modlich U, von der Leyen H, Wicke DC, Ganser A, Stripecke R.

Hum Gene Ther Methods. 2012 Feb;23(1):38-55. doi: 10.1089/hgtb.2011.170.

PMID:
22428979
24.

Preconditioning therapy with lentiviral vector-programmed dendritic cells accelerates the homeostatic expansion of antigen-reactive human T cells in NOD.Rag1-/-.IL-2rγc-/- mice.

Salguero G, Sundarasetty BS, Borchers S, Wedekind D, Eiz-Vesper B, Velaga S, Jirmo AC, Behrens G, Warnecke G, Knöfel AK, Blasczyk R, Mischak-Weissinger E, Ganser A, Stripecke R.

Hum Gene Ther. 2011 Oct;22(10):1209-24. doi: 10.1089/hum.2010.215. Epub 2011 Jul 27.

25.

Elevated frequencies of leukemic myeloid and plasmacytoid dendritic cells in acute myeloid leukemia with the FLT3 internal tandem duplication.

Rickmann M, Krauter J, Stamer K, Heuser M, Salguero G, Mischak-Weissinger E, Ganser A, Stripecke R.

Ann Hematol. 2011 Sep;90(9):1047-58. doi: 10.1007/s00277-011-1231-2. Epub 2011 Apr 26.

26.

Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells.

Pincha M, Salguero G, Wedekind D, Sundarasetty BS, Lin A, Kasahara N, Brugman MH, Jirmo AC, Modlich U, Gutzmer R, Büsche G, Ganser A, Stripecke R.

Gene Ther. 2011 Aug;18(8):750-64. doi: 10.1038/gt.2011.15. Epub 2011 Mar 17.

27.

Two cases of toxic anterior segment syndrome from generic trypan blue.

Buzard K, Zhang JR, Thumann G, Stripecke R, Sunalp M.

J Cataract Refract Surg. 2010 Dec;36(12):2195-9. doi: 10.1016/j.jcrs.2010.09.017.

PMID:
21111323
28.

Lentiviral vectors for immunization: an inflammatory field.

Pincha M, Sundarasetty BS, Stripecke R.

Expert Rev Vaccines. 2010 Mar;9(3):309-21. doi: 10.1586/erv.10.9. Review.

PMID:
20218859
29.

Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8(+) T cell responses.

Jirmo AC, Koya RC, Sundarasetty BS, Pincha M, Yu GY, Lai M, Bakshi R, Schlaphoff V, Grabowski J, Behrens G, Wedemeyer H, Stripecke R.

Vaccine. 2010 Jan 22;28(4):922-33. doi: 10.1016/j.vaccine.2009.10.150. Epub 2009 Nov 18.

PMID:
19931383
30.

Lentiviral vector-mediated genetic programming of mouse and human dendritic cells.

Stripecke R.

Methods Mol Biol. 2009;506:139-58. doi: 10.1007/978-1-59745-409-4_11.

PMID:
19110625
31.

Anti-tumor effect of DNA-based vaccination and dSLIM immunomodulatory molecules in mice with Ph+ acute lymphoblastic leukaemia.

Köchling J, Prada J, Bahrami M, Stripecke R, Seeger K, Henze G, Wittig B, Schmidt M.

Vaccine. 2008 Aug 26;26(36):4669-75. doi: 10.1016/j.vaccine.2008.06.094. Epub 2008 Jul 17.

PMID:
18639600
32.

Clarifying CB2 receptor-dependent and independent effects of THC on human lung epithelial cells.

Sarafian T, Montes C, Harui A, Beedanagari SR, Kiertscher S, Stripecke R, Hossepian D, Kitchen C, Kern R, Belperio J, Roth MD.

Toxicol Appl Pharmacol. 2008 Sep 15;231(3):282-90. doi: 10.1016/j.taap.2008.05.001. Epub 2008 May 9.

33.

CREB is a critical regulator of normal hematopoiesis and leukemogenesis.

Cheng JC, Kinjo K, Judelson DR, Chang J, Wu WS, Schmid I, Shankar DB, Kasahara N, Stripecke R, Bhatia R, Landaw EM, Sakamoto KM.

Blood. 2008 Feb 1;111(3):1182-92. Epub 2007 Nov 1.

34.

Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression.

Kimura T, Koya RC, Anselmi L, Sternini C, Wang HJ, Comin-Anduix B, Prins RM, Faure-Kumar E, Rozengurt N, Cui Y, Kasahara N, Stripecke R.

Mol Ther. 2007 Jul;15(7):1390-9. Epub 2007 May 1.

35.

Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.

Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R.

Mol Ther. 2007 May;15(5):971-80. Epub 2007 Mar 20.

36.

Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes.

Haga K, Lemp NA, Logg CR, Nagashima J, Faure-Kumar E, Gomez GG, Kruse CA, Mendez R, Stripecke R, Kasahara N, Cicciarelli JC.

Transplant Proc. 2006 Dec;38(10):3184-8. Erratum in: Transplant Proc. 2007 Jan-Feb;39(1):314. Kasahara, N A [corrected to Kasahara, N].

37.

The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity.

Prins RM, Craft N, Bruhn KW, Khan-Farooqi H, Koya RC, Stripecke R, Miller JF, Liau LM.

J Immunol. 2006 Jan 1;176(1):157-64.

38.

Cytogenetic characterization of a BCR-ABL transduced mouse cell line.

Rudolph C, Hegazy AN, von Neuhoff N, Steinemann D, Schröck E, Stripecke R, Klein C, Schlegelberger B.

Cancer Genet Cytogenet. 2005 Aug;161(1):51-6.

PMID:
16080957
40.

Potent maturation of monocyte-derived dendritic cells after CD40L lentiviral gene delivery.

Koya RC, Kasahara N, Favaro PM, Lau R, Ta HQ, Weber JS, Stripecke R.

J Immunother. 2003 Sep-Oct;26(5):451-60.

PMID:
12973034
41.

Protection of mice against Philadelphia chromosome-positive acute lymphoblastic leukemia by cell-based vaccination using nonviral, minimalistic expression vectors and immunomodulatory oligonucleotides.

Köchling J, König-Merediz SA, Stripecke R, Buchwald D, Korte A, Von Einsiedel HG, Sack F, Henze G, Seeger K, Wittig B, Schmidt M.

Clin Cancer Res. 2003 Aug 1;9(8):3142-9.

42.
43.

Immunotherapy with acute leukemia cells modified into antigen-presenting cells: ex vivo culture and gene transfer methods.

Stripecke R, Levine AM, Pullarkat V, Cardoso AA.

Leukemia. 2002 Oct;16(10):1974-83. Review.

45.

Receptor-specific targeting mediated by the coexpression of a targeted murine leukemia virus envelope protein and a binding-defective influenza hemagglutinin protein.

Lin AH, Kasahara N, Wu W, Stripecke R, Empig CL, Anderson WF, Cannon PM.

Hum Gene Ther. 2001 Mar 1;12(4):323-32.

PMID:
11242525
46.
48.

Immune response to green fluorescent protein: implications for gene therapy.

Stripecke R, Carmen Villacres M, Skelton D, Satake N, Halene S, Kohn D.

Gene Ther. 1999 Jul;6(7):1305-12.

PMID:
10455440
49.

Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectors.

Case SS, Price MA, Jordan CT, Yu XJ, Wang L, Bauer G, Haas DL, Xu D, Stripecke R, Naldini L, Kohn DB, Crooks GM.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2988-93.

50.

Gene delivery to human B-precursor acute lymphoblastic leukemia cells.

Mascarenhas L, Stripecke R, Case SS, Xu D, Weinberg KI, Kohn DB.

Blood. 1998 Nov 15;92(10):3537-45.

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