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Items: 1 to 50 of 76

1.

Efficacy of Chitosan-Based Dressing for Control of Bleeding in Excisional Wounds.

Stricker-Krongrad AH, Alikhassy Z, Matsangos N, Sebastian R, Marti G, Lay F, Harmon JW.

Eplasty. 2018 Mar 10;18:e14. eCollection 2018.

2.

Comparison of a microsphere-based platform with a multiplex flow cytometric assay for determination of circulating cytokines in the mouse.

Stricker-Krongrad A, Shoemake C, Zhong M, Liu J, Bouchard G.

BMC Clin Pathol. 2018 Jan 6;18:1. doi: 10.1186/s12907-017-0068-6. eCollection 2018.

3.

Development of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments.

Zhong M, Shoemake C, Fuller A, White D, Hanks C, Brocksmith D, Liu J, Gad S, Bouchard G, Stricker-Krongrad A.

Int J Toxicol. 2017 Mar/Apr;36(2):113-123. doi: 10.1177/1091581816686049. Epub 2017 Feb 15.

PMID:
28196426
4.

The importance of minipigs in dermal safety assessment: an overview.

Stricker-Krongrad A, Shoemake CR, Liu J, Brocksmith D, Bouchard G.

Cutan Ocul Toxicol. 2017 Jun;36(2):105-113. doi: 10.1080/15569527.2016.1178277. Epub 2016 May 10. Review.

PMID:
27161161
5.

The Miniature Swine as a Model in Experimental and Translational Medicine.

Stricker-Krongrad A, Shoemake CR, Bouchard GF.

Toxicol Pathol. 2016 Jun;44(4):612-23. doi: 10.1177/0192623316641784. Epub 2016 Apr 12.

PMID:
27073085
6.

Pigs in Toxicology: Breed Differences in Metabolism and Background Findings.

Helke KL, Nelson KN, Sargeant AM, Jacob B, McKeag S, Haruna J, Vemireddi V, Greeley M, Brocksmith D, Navratil N, Stricker-Krongrad A, Hollinger C.

Toxicol Pathol. 2016 Jun;44(4):575-90. doi: 10.1177/0192623316639389. Epub 2016 Apr 4. Review.

PMID:
27044377
7.

Tolerable Levels of Nonclinical Vehicles and Formulations Used in Studies by Multiple Routes in Multiple Species With Notes on Methods to Improve Utility.

Gad SC, Spainhour CB, Shoemake C, Pallman DR, Stricker-Krongrad A, Downing PA, Seals RE, Eagle LA, Polhamus K, Daly J.

Int J Toxicol. 2016 Mar-Apr;35(2):95-178. doi: 10.1177/1091581815622442. Epub 2016 Jan 10. Review.

PMID:
26755718
8.

Miniature Swine Breeds in Toxicology and Drug Safety Assessments: What to Expect during Clinical and Pathology Evaluations.

Stricker-Krongrad A, Shoemake CR, Pereira ME, Gad SC, Brocksmith D, Bouchard GF.

Toxicol Pathol. 2016 Apr;44(3):421-7. doi: 10.1177/0192623315613337. Epub 2015 Dec 10.

PMID:
26656239
9.

Background Pathological Changes in Minipigs: A Comparison of the Incidence and Nature among Different Breeds and Populations of Minipigs.

Helke KL, Nelson KN, Sargeant AM, Jacob B, McKeag S, Haruna J, Vemireddi V, Greeley M, Brocksmith D, Navratil N, Stricker-Krongrad A, Hollinger C.

Toxicol Pathol. 2016 Apr;44(3):325-37. doi: 10.1177/0192623315611762. Epub 2015 Nov 3.

PMID:
26534940
10.

Effects of an alpha-4 integrin inhibitor on restenosis in a new porcine model combining endothelial denudation and stent placement.

Braun A, Dofiles L, Rousselle S, Guerrero L, Gunther J, Yednock T, Stricker-Krongrad A, Messersmith E.

PLoS One. 2010 Dec 13;5(12):e14314. doi: 10.1371/journal.pone.0014314.

11.

Measurement of glomerular filtration rate in anesthetized and conscious rhesus monkeys (Macaca mulatta).

Rabito CA, van Tongeren S, Zavorskas PA, Stricker-Krongrad A, Robb J, Haupert GT Jr.

Am J Vet Res. 2010 Dec;71(12):1492-9. doi: 10.2460/ajvr.71.12.1492.

PMID:
21118002
12.

Investigation of 4-piperidinols as novel H3 antagonists.

Anderson JT, Campbell M, Wang J, Brunden KR, Harrington JJ, Stricker-Krongrad A, Song J, Doucette C, Murphy S, Bennani YL.

Bioorg Med Chem Lett. 2010 Nov 1;20(21):6246-9. doi: 10.1016/j.bmcl.2010.08.099. Epub 2010 Aug 24.

PMID:
20833043
13.

3-Indolyl sultams as selective CRTh2 antagonists.

Tumey LN, Robarge MJ, Gleason E, Song J, Murphy SM, Ekema G, Doucette C, Hanniford D, Palmer M, Pawlowski G, Danzig J, Loftus M, Hunady K, Sherf B, Mays RW, Stricker-Krongrad A, Brunden KR, Bennani YL, Harrington JJ.

Bioorg Med Chem Lett. 2010 Jun 1;20(11):3287-90. doi: 10.1016/j.bmcl.2010.04.046. Epub 2010 Apr 14.

PMID:
20457519
14.

The effects of drug transporter inhibitors on the pharmacokinetics and tissue distribution of methotrexate in normal and tumor-bearing mice: a microdialysis study.

Sani SN, Henry K, Böhlke M, Kim J, Stricker-Krongrad A, Maher TJ.

Cancer Chemother Pharmacol. 2010 May;66(1):159-69. doi: 10.1007/s00280-009-1146-y. Epub 2009 Oct 9.

PMID:
19816684
15.

Responsiveness of obese Zucker rats to [D-Trp34]-NPY supports the targeting of Y5 receptor for obesity treatment.

Beck B, Richy S, Stricker-Krongrad A.

Nutr Neurosci. 2007 Oct-Dec;10(5-6):211-4.

PMID:
18284029
16.

The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonist.

Huck BR, Llamas L, Robarge MJ, Dent TC, Song J, Hodnick WF, Crumrine C, Stricker-Krongrad A, Harrington J, Brunden KR, Bennani YL.

Bioorg Med Chem Lett. 2006 Aug 1;16(15):4130-4. Epub 2006 Jun 5.

PMID:
16750364
17.

Mice deleted for fatty acid transport protein 5 have defective bile acid conjugation and are protected from obesity.

Hubbard B, Doege H, Punreddy S, Wu H, Huang X, Kaushik VK, Mozell RL, Byrnes JJ, Stricker-Krongrad A, Chou CJ, Tartaglia LA, Lodish HF, Stahl A, Gimeno RE.

Gastroenterology. 2006 Apr;130(4):1259-69.

PMID:
16618417
18.

The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonists.

Huck BR, Llamas L, Robarge MJ, Dent TC, Song J, Hodnick WF, Crumrine C, Stricker-Krongrad A, Harrington J, Brunden KR, Bennani YL.

Bioorg Med Chem Lett. 2006 Jun 1;16(11):2891-4. Epub 2006 Mar 20.

PMID:
16546379
19.

Development of homogeneous high-affinity agonist binding assays for 5-HT2 receptor subtypes.

Song J, Hanniford D, Doucette C, Graham E, Poole MF, Ting A, Sherf B, Harrington J, Brunden K, Stricker-Krongrad A.

Assay Drug Dev Technol. 2005 Dec;3(6):649-59.

PMID:
16438660
20.

Evaluation of functional and binding assays in cells expressing either recombinant or endogenous hERG channel.

Murphy SM, Palmer M, Poole MF, Padegimas L, Hunady K, Danzig J, Gill S, Gill R, Ting A, Sherf B, Brunden K, Stricker-Krongrad A.

J Pharmacol Toxicol Methods. 2006 Jul-Aug;54(1):42-55. Epub 2005 Dec 2.

PMID:
16326118
21.

Identification of novel and improved antimitotic agents derived from noscapine.

Anderson JT, Ting AE, Boozer S, Brunden KR, Crumrine C, Danzig J, Dent T, Faga L, Harrington JJ, Hodnick WF, Murphy SM, Pawlowski G, Perry R, Raber A, Rundlett SE, Stricker-Krongrad A, Wang J, Bennani YL.

J Med Chem. 2005 Nov 17;48(23):7096-8.

PMID:
16279766
22.

Generation of cell lines for drug discovery through random activation of gene expression: application to the human histamine H3 receptor.

Song J, Doucette C, Hanniford D, Hunady K, Wang N, Sherf B, Harrington JJ, Brunden KR, Stricker-Krongrad A.

Assay Drug Dev Technol. 2005 Jun;3(3):309-18.

PMID:
15971992
23.

Peptide S is a novel potent inhibitor of voluntary and fast-induced food intake in rats.

Beck B, Fernette B, Stricker-Krongrad A.

Biochem Biophys Res Commun. 2005 Jul 8;332(3):859-65.

PMID:
15919054
24.

Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists.

Robarge MJ, Bom DC, Tumey LN, Varga N, Gleason E, Silver D, Song J, Murphy SM, Ekema G, Doucette C, Hanniford D, Palmer M, Pawlowski G, Danzig J, Loftus M, Hunady K, Sherf BA, Mays RW, Stricker-Krongrad A, Brunden KR, Harrington JJ, Bennani YL.

Bioorg Med Chem Lett. 2005 Mar 15;15(6):1749-53.

PMID:
15745833
25.

ICAM-1 and beta2 integrin deficiency impairs fat oxidation and insulin metabolism during fasting.

Babic AM, Wang HW, Lai MJ, Daniels TG, Felbinger TW, Burger PC, Stricker-Krongrad A, Wagner DD.

Mol Med. 2004 Jul-Dec;10(7-12):72-9.

26.
27.

Feeding response to ghrelin agonist and antagonist in lean and obese Zucker rats.

Beck B, Richy S, Stricker-Krongrad A.

Life Sci. 2004 Dec 10;76(4):473-8.

PMID:
15530508
28.

Feeding response to a potent prolactin-releasing peptide agonist in lean and obese Zucker rats.

Beck B, Max JP, Richy S, Stricker-Krongrad A.

Brain Res. 2004 Jul 30;1016(1):135-8.

PMID:
15234262
29.

Resistance to the orexigenic effect of ghrelin in dietary-induced obesity in mice: reversal upon weight loss.

Perreault M, Istrate N, Wang L, Nichols AJ, Tozzo E, Stricker-Krongrad A.

Int J Obes Relat Metab Disord. 2004 Jul;28(7):879-85.

PMID:
15111983
30.

Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle.

Kim JK, Gimeno RE, Higashimori T, Kim HJ, Choi H, Punreddy S, Mozell RL, Tan G, Stricker-Krongrad A, Hirsch DJ, Fillmore JJ, Liu ZX, Dong J, Cline G, Stahl A, Lodish HF, Shulman GI.

J Clin Invest. 2004 Mar;113(5):756-63.

31.

The prolactin-releasing peptide receptor (GPR10) regulates body weight homeostasis in mice.

Gu W, Geddes BJ, Zhang C, Foley KP, Stricker-Krongrad A.

J Mol Neurosci. 2004;22(1-2):93-103.

PMID:
14742914
32.

Ghrelin and body weight regulation in the obese Zucker rat in relation to feeding state and dark/light cycle.

Beck B, Richy S, Stricker-Krongrad A.

Exp Biol Med (Maywood). 2003 Nov;228(10):1124-31.

PMID:
14610250
33.

Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality.

Gimeno RE, Hirsch DJ, Punreddy S, Sun Y, Ortegon AM, Wu H, Daniels T, Stricker-Krongrad A, Lodish HF, Stahl A.

J Biol Chem. 2003 Dec 5;278(49):49512-6. Epub 2003 Sep 24.

34.

Modulation of hypothalamic hypocretin/orexin mRNA expression by glucocorticoids.

Stricker-Krongrad A, Beck B.

Biochem Biophys Res Commun. 2002 Aug 9;296(1):129-33.

PMID:
12147238
35.

Obesity is associated with decreasing levels of the circulating soluble leptin receptor in humans.

Ogier V, Ziegler O, Méjean L, Nicolas JP, Stricker-Krongrad A.

Int J Obes Relat Metab Disord. 2002 Apr;26(4):496-503.

PMID:
12075576
36.

PTP1B regulates leptin signal transduction in vivo.

Zabolotny JM, Bence-Hanulec KK, Stricker-Krongrad A, Haj F, Wang Y, Minokoshi Y, Kim YB, Elmquist JK, Tartaglia LA, Kahn BB, Neel BG.

Dev Cell. 2002 Apr;2(4):489-95.

37.

Ghrelin, macronutrient intake and dietary preferences in long-evans rats.

Beck B, Musse N, Stricker-Krongrad A.

Biochem Biophys Res Commun. 2002 Apr 12;292(4):1031-5.

PMID:
11944918
38.

Effects of long-term ingestion of aspartame on hypothalamic neuropeptide Y, plasma leptin and body weight gain and composition.

Beck B, Burlet A, Max JP, Stricker-Krongrad A.

Physiol Behav. 2002 Feb 1-15;75(1-2):41-7.

PMID:
11890951
39.

Plasma leptin and hypothalamic neuropeptide Y and galanin levels in Long-Evans rats with marked dietary preferences.

Beck B, Stricker-Krongrad A, Burlet A, Cumin F, Burlet C.

Nutr Neurosci. 2001;4(1):39-50.

PMID:
11842875
40.

Orexins/hypocretins in the ob/ob mouse: hypothalamic gene expression, peptide content and metabolic effects.

Stricker-Krongrad A, Richy S, Beck B.

Regul Pept. 2002 Mar 15;104(1-3):11-20.

PMID:
11830271
41.

Opposite regulation of hypothalamic orexin and neuropeptide Y receptors and peptide expressions in obese Zucker rats.

Beck B, Richy S, Dimitrov T, Stricker-Krongrad A.

Biochem Biophys Res Commun. 2001 Aug 24;286(3):518-23.

PMID:
11511089
42.

Central and peripheral dysregulation of melanin-concentrating hormone in obese Zucker rats.

Stricker-Krongrad A, Dimitrov T, Beck B.

Brain Res Mol Brain Res. 2001 Aug 15;92(1-2):43-8.

PMID:
11483240
43.

Identification of leptin-induced transcripts in the mouse hypothalamus.

White DW, Zhou J, Stricker-Krongrad A, Ge P, Morgenstern JP, Dembski M, Tartaglia LA.

Diabetes. 2000 Sep;49(9):1443-50.

PMID:
10969827
44.

NPY Y5 receptor subtype. Pharmacological characterization with antisense oligodeoxynucleotide screening strategy.

Schaffhauser AO, Stricker-Krongrad A, Hofbauer KG.

Methods Mol Biol. 2000;153:129-50. No abstract available.

PMID:
10957990
45.

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice.

Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB.

Mol Cell Biol. 2000 Aug;20(15):5479-89.

46.

A peptide leptin antagonist reduces food intake in rodents.

Brunner L, Whitebread S, Leconte I, Stricker-Krongrad A, Cumin F, Chiesi M, Levens N.

Int J Obes Relat Metab Disord. 1999 May;23(5):463-9.

PMID:
10375048
47.

Induction of obesity and hyperleptinemia by central glucocorticoid infusion in the rat.

Zakrzewska KE, Cusin I, Stricker-Krongrad A, Boss O, Ricquier D, Jeanrenaud B, Rohner-Jeanrenaud F.

Diabetes. 1999 Feb;48(2):365-70.

PMID:
10334315
48.

Hypothalamic neuropeptide Y and plasma leptin after long-term high-fat feeding in the rat.

Stricker-Krongrad A, Cumin F, Burlet C, Beck B.

Neurosci Lett. 1998 Oct 2;254(3):157-60.

PMID:
10214981
49.

Independent feeding and metabolic actions of orexins in mice.

Lubkin M, Stricker-Krongrad A.

Biochem Biophys Res Commun. 1998 Dec 18;253(2):241-5.

PMID:
9878522
50.

Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor.

Criscione L, Rigollier P, Batzl-Hartmann C, Rüeger H, Stricker-Krongrad A, Wyss P, Brunner L, Whitebread S, Yamaguchi Y, Gerald C, Heurich RO, Walker MW, Chiesi M, Schilling W, Hofbauer KG, Levens N.

J Clin Invest. 1998 Dec 15;102(12):2136-45.

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