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Items: 1 to 50 of 650

1.

Hereditary hyperferritinaemia-cataract syndrome (HHCS) - an underestimated condition: ferritin light chain variant spectrum in German families.

Volkmann M, Richter R, Herrmann T, Hentze S, Hör M, Hasche H, Selle B, Stremmel W, Gehrke SG.

Clin Chem Lab Med. 2019 Jun 18. pii: /j/cclm.ahead-of-print/cclm-2018-1354/cclm-2018-1354.xml. doi: 10.1515/cclm-2018-1354. [Epub ahead of print]

PMID:
31211687
2.

The interesting case-orphan diseases-double trouble.

Reuner U, Stremmel W, Weiskirchen R.

Ann Transl Med. 2019 Apr;7(Suppl 2):S74. doi: 10.21037/atm.2019.04.31.

3.

Clinical features of Wilson disease.

Stremmel W, Merle U, Weiskirchen R.

Ann Transl Med. 2019 Apr;7(Suppl 2):S61. doi: 10.21037/atm.2019.01.20. Review.

4.

Editorial for focused issue "Wilson Disease: From Genetics to Management of Disease".

Weiskirchen R, Stremmel W.

Ann Transl Med. 2019 Apr;7(Suppl 2):S55. doi: 10.21037/atm.2018.12.06. No abstract available.

5.

Hepatic Encephalopathy Aggravated by Systemic Inflammation.

Manzhalii E, Virchenko O, Falalyeyeva T, Moiseienko V, Nykula T, Kondratiuk V, Savchuk O, Beregova T, Stremmel W.

Dig Dis. 2019 Jun 6:1-9. doi: 10.1159/000500717. [Epub ahead of print]

PMID:
31170723
6.

The Detergent Effect of Mesalazine Interferes with Phosphatidylcholine Binding to Mucin 2.

Stremmel W, Staffer S, Gehrke S.

Inflamm Intest Dis. 2019 Feb;3(3):107-115. doi: 10.1159/000493347. Epub 2018 Oct 18.

7.

An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1.

Exner T, Romero-Brey I, Yifrach E, Rivera-Monroy J, Schrul B, Zouboulis CC, Stremmel W, Honsho M, Bartenschlager R, Zalckvar E, Poppelreuther M, Füllekrug J.

J Cell Sci. 2019 Mar 18;132(6). pii: jcs223016. doi: 10.1242/jcs.223016.

PMID:
30745342
8.

Survival of Hepatocellular Carcinoma Patients Treated with Sorafenib beyond Progression.

Apostolidis L, Pfeiffenberger J, Gotthardt D, Radeleff B, Mehrabi A, Schemmer P, Jäger D, Schirmacher P, Stremmel W, Schulze-Bergkamen H, Springfeld C, Weiss KH.

Gastrointest Tumors. 2018 Sep;5(1-2):38-46. doi: 10.1159/000487635. Epub 2018 Apr 11.

9.

Shear-Enhanced Dynamic Adhesion of Lactobacillus rhamnosus GG on Intestinal Epithelia: Correlative Effect of Protein Expression and Interface Mechanics.

Eshrati M, Amadei F, Staffer S, Stremmel W, Tanaka M.

Langmuir. 2019 Jan 15;35(2):529-537. doi: 10.1021/acs.langmuir.8b02931. Epub 2019 Jan 2.

PMID:
30567428
10.

Elevation of blood lipids in hepatocyte-specific fatty acid transport 4-deficient mice fed with high glucose diets.

Döring S, Seeßle J, Gan-Schreier H, Javaheri B, Jiao L, Cheng Y, Tuma-Kellner S, Liebisch G, Herrmann T, Stremmel W, Chamulitrat W.

Mol Genet Metab. 2019 Jan;126(1):30-38. doi: 10.1016/j.ymgme.2018.11.010. Epub 2018 Nov 23.

PMID:
30497809
11.

Nonclassical Interactions of Phosphatidylcholine with Mucin Protect Intestinal Surfaces: A Microinterferometry Study.

Amadei F, Fröhlich B, Stremmel W, Tanaka M.

Langmuir. 2018 Nov 20;34(46):14046-14057. doi: 10.1021/acs.langmuir.8b03035. Epub 2018 Nov 6.

PMID:
30359036
12.

Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization.

Su J, Gan-Schreier H, Goeppert B, Chamulitrat W, Stremmel W, Pathil A.

Int J Mol Sci. 2018 Oct 20;19(10). pii: E3254. doi: 10.3390/ijms19103254.

13.

Age and Sex but Not ATP7B Genotype Effectively Influence the Clinical Phenotype of Wilson Disease.

Ferenci P, Stremmel W, Członkowska A, Szalay F, Viveiros A, Stättermayer AF, Bruha R, Houwen R, Pop TL, Stauber R, Gschwantler M, Pfeiffenberger J, Yurdaydin C, Aigner E, Steindl-Munda P, Dienes HP, Zoller H, Weiss KH.

Hepatology. 2019 Apr;69(4):1464-1476. doi: 10.1002/hep.30280. Epub 2019 Mar 1.

PMID:
30232804
14.

Real-World Outcomes of Vedolizumab Therapy in Ulcerative Colitis and Crohn's Disease at a Tertiary Referral Center.

Hoffmann P, Krisam J, Stremmel W, Gauss A.

Dig Dis. 2019;37(1):33-44. doi: 10.1159/000492322. Epub 2018 Aug 22.

PMID:
30134234
15.

Bis-choline Tetrathiomolybdate as Old Drug in a New Design for Wilson's Disease: Good for Brain and Liver?

Stremmel W.

Hepatology. 2019 Feb;69(2):901-903. doi: 10.1002/hep.30130. Epub 2018 Dec 28. No abstract available.

PMID:
30070374
16.

Phospholipase A2 of Microbiota as Pathogenetic Determinant to Induce Inflammatory States in Ulcerative Colitis: Therapeutic Implications of Phospholipase A2 Inhibitors.

Stremmel W, Staffer S, Stuhrmann N, Gan-Schreier H, Gauss A, Burger N, Hornuss D.

Inflamm Intest Dis. 2018 Mar;2(3):180-187. doi: 10.1159/000486858. Epub 2018 Mar 6.

17.

Circulating Phospholipid Patterns in NAFLD Patients Associated with a Combination of Metabolic Risk Factors.

Tiwari-Heckler S, Gan-Schreier H, Stremmel W, Chamulitrat W, Pathil A.

Nutrients. 2018 May 21;10(5). pii: E649. doi: 10.3390/nu10050649.

18.

Successful direct acting antiviral (DAA) treatment of HCV/HIV-coinfected patients before and after liver transplantation.

Grottenthaler JM, Werner CR, Steurer M, Spengler U, Berg T, Engelmann C, Wedemeyer H, von Hahn T, Stremmel W, Pathil A, Seybold U, Schott E, Blessin U, Sarrazin C, Welker MW, Harrer E, Scholten S, Hinterleitner C, Lauer UM, Malek NP, Berg CP.

PLoS One. 2018 Jun 6;13(6):e0197544. doi: 10.1371/journal.pone.0197544. eCollection 2018.

19.

Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury.

Ludwig JM, Zhang Y, Chamulitrat W, Stremmel W, Pathil A.

PLoS One. 2018 May 24;13(5):e0197836. doi: 10.1371/journal.pone.0197836. eCollection 2018.

20.

Metallothionein is elevated in liver and duodenum of Atp7b(-/-) mice.

Zhang CC, Volkmann M, Tuma S, Stremmel W, Merle U.

Biometals. 2018 Aug;31(4):617-625. doi: 10.1007/s10534-018-0110-x. Epub 2018 May 7.

PMID:
29732486
21.

Diterpenoid trigonoreidon B isolated from Trigonostemon reidioides alleviates inflammation in models of LPS-stimulated murine macrophages and inflammatory liver injury in mice.

Utaipan T, Suksamrarn A, Kaemchantuek P, Chokchaisiri R, Stremmel W, Chamulitrat W, Chunglok W.

Biomed Pharmacother. 2018 May;101:961-971. doi: 10.1016/j.biopha.2018.02.144. Epub 2018 Mar 22.

PMID:
29635906
22.

Ridinilazole-a novel antibiotic for treatment of Clostridium difficile infection.

Steinebrunner N, Stremmel W, Weiss KH.

J Thorac Dis. 2018 Jan;10(1):118-120. doi: 10.21037/jtd.2017.12.117. No abstract available.

23.

Successful combination of direct antiviral agents in liver-transplanted patients with recurrent hepatitis C virus.

Rupp C, Hippchen T, Neuberger M, Sauer P, Pfeiffenberger J, Stremmel W, Gotthardt DN, Mehrabi A, Weiss KH.

World J Gastroenterol. 2018 Mar 28;24(12):1353-1360. doi: 10.3748/wjg.v24.i12.1353.

24.

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells.

Poppelreuther M, Sander S, Minden F, Dietz MS, Exner T, Du C, Zhang I, Ehehalt F, Knüppel L, Domschke S, Badenhop A, Staudacher S, Ehehalt R, Stremmel W, Thiele C, Heilemann M, Füllekrug J.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jun;1863(6):614-624. doi: 10.1016/j.bbalip.2018.03.003. Epub 2018 Mar 9.

PMID:
29526665
25.

Impact of age at diagnosis on disease progression in patients with primary sclerosing cholangitis.

Rupp C, Rössler A, Zhou T, Rauber C, Friedrich K, Wannhoff A, Weiss KH, Sauer P, Schirmacher P, Süsal C, Stremmel W, Gotthardt DN.

United European Gastroenterol J. 2018 Mar;6(2):255-262. doi: 10.1177/2050640617717156. Epub 2017 Jun 17.

26.

Ursodeoxycholyl lysophosphatidylethanolamide negatively regulates TLR-mediated lipopolysaccharide response in human THP-1-derived macrophages.

Horvatova A, Utaipan T, Otto AC, Zhang Y, Gan-Schreier H, Pavek P, Pathil A, Stremmel W, Chamulitrat W.

Eur J Pharmacol. 2018 Apr 15;825:63-74. doi: 10.1016/j.ejphar.2018.02.030. Epub 2018 Feb 20.

PMID:
29475064
27.

Predictors of functional benefit of hepatitis C therapy in a 'real-life' cohort.

Steinebrunner N, Stein K, Sandig C, Bruckner T, Stremmel W, Pathil A.

World J Gastroenterol. 2018 Feb 21;24(7):852-861. doi: 10.3748/wjg.v24.i7.852.

28.

Treatment efficacy of a probiotic preparation for non-alcoholic steatohepatitis: A pilot trial.

Manzhalii E, Virchenko O, Falalyeyeva T, Beregova T, Stremmel W.

J Dig Dis. 2017 Dec;18(12):698-703. doi: 10.1111/1751-2980.12561.

PMID:
29148175
29.

Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.

Jiao L, Gan-Schreier H, Zhu X, Wei W, Tuma-Kellner S, Liebisch G, Stremmel W, Chamulitrat W.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Dec;1862(12):1520-1533. doi: 10.1016/j.bbalip.2017.09.001. Epub 2017 Sep 6.

PMID:
28888832
30.

Pregnancy in Wilson's disease: Management and outcome.

Pfeiffenberger J, Beinhardt S, Gotthardt DN, Haag N, Freissmuth C, Reuner U, Gauss A, Stremmel W, Schilsky ML, Ferenci P, Weiss KH.

Hepatology. 2018 Apr;67(4):1261-1269. doi: 10.1002/hep.29490. Epub 2018 Feb 18.

PMID:
28859232
31.

Slow ventricular tachycardia presenting with acute liver failure.

Wannhoff A, Nusshag C, Stremmel W, Merle U.

SAGE Open Med Case Rep. 2017 Jul 12;5:2050313X17718100. doi: 10.1177/2050313X17718100. eCollection 2017.

32.

Comparative assessment of clinical rating scales in Wilson's disease.

Volpert HM, Pfeiffenberger J, Gröner JB, Stremmel W, Gotthardt DN, Schäfer M, Weiss KH, Weiler M.

BMC Neurol. 2017 Jul 21;17(1):140. doi: 10.1186/s12883-017-0921-3.

33.

The overall fatty acid absorption controlled by basolateral chylomicron excretion under regulation of p-JNK1.

Stremmel W, Staffer S, Wannhoff A, Pathil A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Sep;1862(9):917-928. doi: 10.1016/j.bbalip.2017.05.013. Epub 2017 Jun 6.

34.

Genetic Mouse Models with Intestinal-Specific Tight Junction Deletion Resemble an Ulcerative Colitis Phenotype.

Stremmel W, Staffer S, Schneider MJ, Gan-Schreier H, Wannhoff A, Stuhrmann N, Gauss A, Wolburg H, Mahringer A, Swidsinski A, Efferth T.

J Crohns Colitis. 2017 Oct 1;11(10):1247-1257. doi: 10.1093/ecco-jcc/jjx075.

35.

Novel perspectives on Wilson disease treatment.

Rupp C, Stremmel W, Weiss KH.

Handb Clin Neurol. 2017;142:225-230. doi: 10.1016/B978-0-444-63625-6.00019-7. Review.

PMID:
28433106
36.

Wilson disease: symptomatic liver therapy.

Pfeiffenberger J, Weiss KH, Stremmel W.

Handb Clin Neurol. 2017;142:205-209. doi: 10.1016/B978-0-444-63625-6.00017-3. Review.

PMID:
28433104
37.

Von Willebrand factor and alkaline phosphatase predict re-transplantation-free survival after the first liver transplantation.

Wannhoff A, Rauber C, Friedrich K, Rupp C, Stremmel W, Weiss KH, Schemmer P, Gotthardt DN.

United European Gastroenterol J. 2017 Feb;5(1):86-93. doi: 10.1177/2050640616650060. Epub 2016 Jul 8.

38.

Accumulation of phosphatidylcholine on gut mucosal surface is not dominated by electrostatic interactions.

Korytowski A, Abuillan W, Amadei F, Makky A, Gumiero A, Sinning I, Gauss A, Stremmel W, Tanaka M.

Biochim Biophys Acta Biomembr. 2017 May;1859(5):959-965. doi: 10.1016/j.bbamem.2017.02.008. Epub 2017 Feb 15.

39.

Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine.

Stremmel W, Schmidt KV, Schuhmann V, Kratzer F, Garbade SF, Langhans CD, Fricker G, Okun JG.

PLoS One. 2017 Jan 27;12(1):e0170742. doi: 10.1371/journal.pone.0170742. eCollection 2017.

40.

Ursodeoxycholyl Lysophosphatidylethanolamide Protects Against CD95/FAS-Induced Fulminant Hepatitis.

Utaipan T, Otto AC, Gan-Schreier H, Chunglok W, Pathil A, Stremmel W, Chamulitrat W.

Shock. 2017 Aug;48(2):251-259. doi: 10.1097/SHK.0000000000000831.

PMID:
28060213
41.

Carcinoembryonic Antigen Level in Primary Sclerosing Cholangitis Is Not Influenced by Dominant Strictures or Bacterial Cholangitis.

Wannhoff A, Rupp C, Friedrich K, Knierim J, Flechtenmacher C, Weiss KH, Stremmel W, Gotthardt DN.

Dig Dis Sci. 2017 Feb;62(2):510-516. doi: 10.1007/s10620-016-4370-4. Epub 2016 Dec 9.

PMID:
27943017
42.

Control of diabetic hyperglycaemia and insulin resistance through TSC22D4.

Ekim Üstünel B, Friedrich K, Maida A, Wang X, Krones-Herzig A, Seibert O, Sommerfeld A, Jones A, Sijmonsma TP, Sticht C, Gretz N, Fleming T, Nawroth PP, Stremmel W, Rose AJ, Berriel-Diaz M, Blüher M, Herzig S.

Nat Commun. 2016 Nov 9;7:13267. doi: 10.1038/ncomms13267.

43.

Delivery of Copper-chelating Trientine (TETA) to the central nervous system by surface modified liposomes.

Tremmel R, Uhl P, Helm F, Wupperfeld D, Sauter M, Mier W, Stremmel W, Hofhaus G, Fricker G.

Int J Pharm. 2016 Oct 15;512(1):87-95. doi: 10.1016/j.ijpharm.2016.08.040. Epub 2016 Aug 20.

PMID:
27553779
44.

Phosphatidylcholine passes through lateral tight junctions for paracellular transport to the apical side of the polarized intestinal tumor cell-line CaCo2.

Stremmel W, Staffer S, Gan-Schreier H, Wannhoff A, Bach M, Gauss A.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1161-1169. doi: 10.1016/j.bbalip.2016.06.019. Epub 2016 Jun 27.

45.

Intestinal-borne dermatoses significantly improved by oral application of Escherichia coli Nissle 1917.

Manzhalii E, Hornuss D, Stremmel W.

World J Gastroenterol. 2016 Jun 21;22(23):5415-21. doi: 10.3748/wjg.v22.i23.5415.

46.

Evaluation of Biliary Calprotectin as a Biomarker in Primary Sclerosing Cholangitis.

Gauss A, Sauer P, Stiehl A, Rupp C, Krisam J, Leopold Y, Kloeters-Plachky P, Stremmel W, Gotthardt D.

Medicine (Baltimore). 2016 Apr;95(17):e3510. doi: 10.1097/MD.0000000000003510.

47.

Quality of Life Is Related to Fecal Calprotectin Concentrations in Colonic Crohn Disease and Ulcerative Colitis, but not in Ileal Crohn Disease.

Gauss A, Geib T, Hinz U, Schaefert R, Zwickel P, Zawierucha A, Stremmel W, Klute L.

Medicine (Baltimore). 2016 Apr;95(16):e3477. doi: 10.1097/MD.0000000000003477.

48.

CD14 is associated with biliary stricture formation.

Friedrich K, Smit M, Brune M, Giese T, Rupp C, Wannhoff A, Kloeters P, Leopold Y, Denk GU, Weiss KH, Stremmel W, Sauer P, Hohenester S, Schirmacher P, Schemmer P, Gotthardt DN.

Hepatology. 2016 Sep;64(3):843-52. doi: 10.1002/hep.28543. Epub 2016 Apr 20.

PMID:
26970220
49.

A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis.

Wannhoff A, Folseraas T, Brune M, Rupp C, Friedrich K, Knierim J, Weiss KH, Sauer P, Flechtenmacher C, Schirmacher P, Stremmel W, Hov JR, Gotthardt DN.

United European Gastroenterol J. 2016 Feb;4(1):84-91. doi: 10.1177/2050640615581577. Epub 2015 Apr 9.

50.

Microbiological Assessment of Bile and Corresponding Antibiotic Treatment: A Strobe-Compliant Observational Study of 1401 Endoscopic Retrograde Cholangiographies.

Rupp C, Bode K, Weiss KH, Rudolph G, Bergemann J, Kloeters-Plachky P, Chahoud F, Stremmel W, Gotthardt DN, Sauer P.

Medicine (Baltimore). 2016 Mar;95(10):e2390. doi: 10.1097/MD.0000000000002390.

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