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Items: 1 to 50 of 73

1.

Reverse zoonotic tuberculosis transmission from an emerging Uganda I strain between pastoralists and cattle in South-Eastern Nigeria.

Adesokan HK, Akinseye VO, Streicher EM, Van Helden P, Warren RM, Cadmus SI.

BMC Vet Res. 2019 Dec 4;15(1):437. doi: 10.1186/s12917-019-2185-1.

2.

Minority Mycobacterium tuberculosis Genotypic Populations as an Indicator of Subsequent Phenotypic Resistance.

Engelthaler DM, Streicher EM, Kelley EJ, Allender CJ, Wiggins K, Jimenez D, Lemmer D, Vittinghoff E, Theron G, Sirgel FA, Warren RM, Metcalfe JZ.

Am J Respir Cell Mol Biol. 2019 Dec;61(6):789-791. doi: 10.1165/rcmb.2019-0178LE. No abstract available.

PMID:
31774334
3.

Detection of Second Line Drug Resistance among Drug Resistant Mycobacterium Tuberculosis Isolates in Botswana.

Mogashoa T, Melamu P, Derendinger B, Ley SD, Streicher EM, Iketleng T, Mupfumi L, Mokomane M, Kgwaadira B, Rankgoane-Pono G, Tsholofelo TT, Kasvosve I, Moyo S, Warren RM, Gaseitsiwe S.

Pathogens. 2019 Oct 28;8(4). pii: E208. doi: 10.3390/pathogens8040208.

4.

Recovery of Mycobacterium tuberculosis from positive mycobacterium growth indicator tubes stored at room temperature for up to 6 years in low-income and High-Tuberculosis-Burden Country.

Chirenda J, Chipinduro M, de Kock M, Spies C, Sakubani CT, Warren RM, Sampson SL, Streicher EM.

Int J Mycobacteriol. 2019 Apr-Jun;8(2):185-189. doi: 10.4103/ijmy.ijmy_46_19.

5.

Bacterial Genotyping of Central Nervous System Tuberculosis in South Africa: Heterogenic Mycobacterium tuberculosis Infection and Predominance of Lineage 4.

van Leeuwen LM, Versteegen P, Zaharie SD, van Elsland SL, Jordaan A, Streicher EM, Warren RM, van der Kuip M, van Furth AM.

J Clin Microbiol. 2019 Jul 26;57(8). pii: e00415-19. doi: 10.1128/JCM.00415-19. Print 2019 Aug.

PMID:
31189579
6.

Genetic diversity of Mycobacterium tuberculosis strains circulating in Botswana.

Mogashoa T, Melamu P, Ley SD, Streicher EM, Iketleng T, Kelentse N, Mupfumi L, Mokomane M, Kgwaadira B, Novitsky V, Kasvosve I, Moyo S, Warren RM, Gaseitsiwe S.

PLoS One. 2019 May 7;14(5):e0216306. doi: 10.1371/journal.pone.0216306. eCollection 2019.

7.

Genetic diversity of Mycobacterium tuberculosis complex strains isolated from livestock workers and cattle in Nigeria.

Adesokan HK, Streicher EM, van Helden PD, Warren RM, Cadmus SIB.

PLoS One. 2019 Feb 20;14(2):e0211637. doi: 10.1371/journal.pone.0211637. eCollection 2019.

8.

Using routinely collected laboratory data to identify high rifampicin-resistant tuberculosis burden communities in the Western Cape Province, South Africa: A retrospective spatiotemporal analysis.

McIntosh AI, Jenkins HE, White LF, Barnard M, Thomson DR, Dolby T, Simpson J, Streicher EM, Kleinman MB, Ragan EJ, van Helden PD, Murray MB, Warren RM, Jacobson KR.

PLoS Med. 2018 Aug 21;15(8):e1002638. doi: 10.1371/journal.pmed.1002638. eCollection 2018 Aug.

9.

Geospatial distribution of Mycobacterium tuberculosis genotypes in Africa.

Chihota VN, Niehaus A, Streicher EM, Wang X, Sampson SL, Mason P, Källenius G, Mfinanga SG, Pillay M, Klopper M, Kasongo W, Behr MA, Gey van Pittius NC, van Helden PD, Couvin D, Rastogi N, Warren RM.

PLoS One. 2018 Aug 1;13(8):e0200632. doi: 10.1371/journal.pone.0200632. eCollection 2018.

10.

The potential use of rifabutin for treatment of patients diagnosed with rifampicin-resistant tuberculosis.

Whitfield MG, Warren RM, Mathys V, Scott L, De Vos E, Stevens W, Streicher EM, Groenen G, Sirgel FA, Van Rie A.

J Antimicrob Chemother. 2018 Oct 1;73(10):2667-2674. doi: 10.1093/jac/dky248.

11.

Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.

Coll F, Phelan J, Hill-Cawthorne GA, Nair MB, Mallard K, Ali S, Abdallah AM, Alghamdi S, Alsomali M, Ahmed AO, Portelli S, Oppong Y, Alves A, Bessa TB, Campino S, Caws M, Chatterjee A, Crampin AC, Dheda K, Furnham N, Glynn JR, Grandjean L, Ha DM, Hasan R, Hasan Z, Hibberd ML, Joloba M, Jones-López EC, Matsumoto T, Miranda A, Moore DJ, Mocillo N, Panaiotov S, Parkhill J, Penha C, Perdigão J, Portugal I, Rchiad Z, Robledo J, Sheen P, Shesha NT, Sirgel FA, Sola C, Sousa EO, Streicher EM, Van Helden P, Viveiros M, Warren RM, McNerney R, Pain A, Clark TG.

Nat Genet. 2018 May;50(5):764. doi: 10.1038/s41588-018-0074-3.

PMID:
29674744
12.

Biology of clinical strains of Mycobacterium tuberculosis with varying levels of transmission.

Shanley CA, Henao-Tamayo MI, Bipin C, Mugasimangalam R, Verma D, Ordway DJ, Streicher EM, Orme IM.

Tuberculosis (Edinb). 2018 Mar;109:123-133. doi: 10.1016/j.tube.2018.02.003. Epub 2018 Feb 9.

13.

Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.

Coll F, Phelan J, Hill-Cawthorne GA, Nair MB, Mallard K, Ali S, Abdallah AM, Alghamdi S, Alsomali M, Ahmed AO, Portelli S, Oppong Y, Alves A, Bessa TB, Campino S, Caws M, Chatterjee A, Crampin AC, Dheda K, Furnham N, Glynn JR, Grandjean L, Minh Ha D, Hasan R, Hasan Z, Hibberd ML, Joloba M, Jones-López EC, Matsumoto T, Miranda A, Moore DJ, Mocillo N, Panaiotov S, Parkhill J, Penha C, Perdigão J, Portugal I, Rchiad Z, Robledo J, Sheen P, Shesha NT, Sirgel FA, Sola C, Oliveira Sousa E, Streicher EM, Helden PV, Viveiros M, Warren RM, McNerney R, Pain A, Clark TG.

Nat Genet. 2018 Feb;50(2):307-316. doi: 10.1038/s41588-017-0029-0. Epub 2018 Jan 22. Erratum in: Nat Genet. 2018 Apr 19;:.

14.

Genetic diversity and potential routes of transmission of Mycobacterium bovis in Mozambique.

Machado A, Rito T, Ghebremichael S, Muhate N, Maxhuza G, Macuamule C, Moiane I, Macucule B, Marranangumbe AS, Baptista J, Manguele J, Koivula T, Streicher EM, Warren RM, Kallenius G, van Helden P, Correia-Neves M.

PLoS Negl Trop Dis. 2018 Jan 18;12(1):e0006147. doi: 10.1371/journal.pntd.0006147. eCollection 2018 Jan.

15.

Isoniazid Resistance and Dosage as Treatment for Patients with Tuberculosis.

Nagel S, Streicher EM, Klopper M, Warren RM, Van Helden PD.

Curr Drug Metab. 2017;18(11):1030-1039. doi: 10.2174/1389200218666171031121905. Review.

PMID:
29086682
16.

Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents.

Kapp E, Visser H, Sampson SL, Malan SF, Streicher EM, Foka GB, Warner DF, Omoruyi SI, Enogieru AB, Ekpo OE, Zindo FT, Joubert J.

Molecules. 2017 Sep 30;22(10). pii: E1644. doi: 10.3390/molecules22101644.

17.

Implications of Failure to Routinely Diagnose Resistance to Second-Line Drugs in Patients With Rifampicin-Resistant Tuberculosis on Xpert MTB/RIF: A Multisite Observational Study.

Jacobson KR, Barnard M, Kleinman MB, Streicher EM, Ragan EJ, White LF, Shapira O, Dolby T, Simpson J, Scott L, Stevens W, van Helden PD, Van Rie A, Warren RM.

Clin Infect Dis. 2017 Jun 1;64(11):1502-1508. doi: 10.1093/cid/cix128. Erratum in: Clin Infect Dis. 2017 Oct 15;65(8):1431-1433.

18.

Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study.

Dheda K, Limberis JD, Pietersen E, Phelan J, Esmail A, Lesosky M, Fennelly KP, Te Riele J, Mastrapa B, Streicher EM, Dolby T, Abdallah AM, Ben-Rached F, Simpson J, Smith L, Gumbo T, van Helden P, Sirgel FA, McNerney R, Theron G, Pain A, Clark TG, Warren RM.

Lancet Respir Med. 2017 Apr;5(4):269-281. doi: 10.1016/S2213-2600(16)30433-7. Epub 2017 Jan 19.

PMID:
28109869
19.

Prevalence of pyrazinamide resistance across the spectrum of drug resistant phenotypes of Mycobacterium tuberculosis.

Whitfield MG, Streicher EM, Dolby T, Simpson JA, Sampson SL, Van Helden PD, Van Rie A, Warren RM.

Tuberculosis (Edinb). 2016 Jul;99:128-30. doi: 10.1016/j.tube.2016.05.003. Epub 2016 May 30.

20.

Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Patients with Tuberculosis.

Chengalroyen MD, Beukes GM, Gordhan BG, Streicher EM, Churchyard G, Hafner R, Warren R, Otwombe K, Martinson N, Kana BD.

Am J Respir Crit Care Med. 2016 Dec 15;194(12):1532-1540.

21.

Mapping of Mycobacterium tuberculosis Complex Genetic Diversity Profiles in Tanzania and Other African Countries.

Mbugi EV, Katale BZ, Streicher EM, Keyyu JD, Kendall SL, Dockrell HM, Michel AL, Rweyemamu MM, Warren RM, Matee MI, van Helden PD, Couvin D, Rastogi N.

PLoS One. 2016 May 5;11(5):e0154571. doi: 10.1371/journal.pone.0154571. eCollection 2016.

22.

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.

Phelan JE, Coll F, Bergval I, Anthony RM, Warren R, Sampson SL, Gey van Pittius NC, Glynn JR, Crampin AC, Alves A, Bessa TB, Campino S, Dheda K, Grandjean L, Hasan R, Hasan Z, Miranda A, Moore D, Panaiotov S, Perdigao J, Portugal I, Sheen P, de Oliveira Sousa E, Streicher EM, van Helden PD, Viveiros M, Hibberd ML, Pain A, McNerney R, Clark TG.

BMC Genomics. 2016 Feb 29;17:151. doi: 10.1186/s12864-016-2467-y.

23.

Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value.

Farhat MR, Sultana R, Iartchouk O, Bozeman S, Galagan J, Sisk P, Stolte C, Nebenzahl-Guimaraes H, Jacobson K, Sloutsky A, Kaur D, Posey J, Kreiswirth BN, Kurepina N, Rigouts L, Streicher EM, Victor TC, Warren RM, van Soolingen D, Murray M.

Am J Respir Crit Care Med. 2016 Sep 1;194(5):621-30. doi: 10.1164/rccm.201510-2091OC.

24.

Isolation and Potential for Transmission of Mycobacterium bovis at Human-livestock-wildlife Interface of the Serengeti Ecosystem, Northern Tanzania.

Katale BZ, Mbugi EV, Siame KK, Keyyu JD, Kendall S, Kazwala RR, Dockrell HM, Fyumagwa RD, Michel AL, Rweyemamu M, Streicher EM, Warren RM, van Helden P, Matee MI.

Transbound Emerg Dis. 2017 Jun;64(3):815-825. doi: 10.1111/tbed.12445. Epub 2015 Nov 13.

25.

Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates.

Black PA, de Vos M, Louw GE, van der Merwe RG, Dippenaar A, Streicher EM, Abdallah AM, Sampson SL, Victor TC, Dolby T, Simpson JA, van Helden PD, Warren RM, Pain A.

BMC Genomics. 2015 Oct 24;16:857. doi: 10.1186/s12864-015-2067-2.

26.

Molecular Epidemiological Interpretation of the Epidemic of Extensively Drug-Resistant Tuberculosis in South Africa.

Streicher EM, Sampson SL, Dheda K, Dolby T, Simpson JA, Victor TC, Gey van Pittius NC, van Helden PD, Warren RM.

J Clin Microbiol. 2015 Nov;53(11):3650-3. doi: 10.1128/JCM.01414-15. Epub 2015 Sep 2.

27.

Mycobacterium tuberculosis pncA Polymorphisms That Do Not Confer Pyrazinamide Resistance at a Breakpoint Concentration of 100 Micrograms per Milliliter in MGIT.

Whitfield MG, Warren RM, Streicher EM, Sampson SL, Sirgel FA, van Helden PD, Mercante A, Willby M, Hughes K, Birkness K, Morlock G, van Rie A, Posey JE.

J Clin Microbiol. 2015 Nov;53(11):3633-5. doi: 10.1128/JCM.01001-15. Epub 2015 Aug 19.

28.

Novel katG mutations causing isoniazid resistance in clinical M. tuberculosis isolates.

Torres JN, Paul LV, Rodwell TC, Victor TC, Amallraja AM, Elghraoui A, Goodmanson AP, Ramirez-Busby SM, Chawla A, Zadorozhny V, Streicher EM, Sirgel FA, Catanzaro D, Rodrigues C, Gler MT, Crudu V, Catanzaro A, Valafar F.

Emerg Microbes Infect. 2015 Jul;4(7):e42. doi: 10.1038/emi.2015.42. Epub 2015 Jul 15.

29.

A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-Analysis.

Whitfield MG, Soeters HM, Warren RM, York T, Sampson SL, Streicher EM, van Helden PD, van Rie A.

PLoS One. 2015 Jul 28;10(7):e0133869. doi: 10.1371/journal.pone.0133869. eCollection 2015. Review.

30.

Genetic diversity of Mycobacterium tuberculosis isolated from tuberculosis patients in the Serengeti ecosystem in Tanzania.

Mbugi EV, Katale BZ, Siame KK, Keyyu JD, Kendall SL, Dockrell HM, Streicher EM, Michel AL, Rweyemamu MM, Warren RM, Matee MI, van Helden PD.

Tuberculosis (Edinb). 2015 Mar;95(2):170-8. doi: 10.1016/j.tube.2014.11.006. Epub 2014 Nov 29.

31.

Rapid sequencing of the Mycobacterium tuberculosis pncA gene for detection of pyrazinamide susceptibility.

Streicher EM, Maharaj K, York T, Van Heerden C, Barnard M, Diacon A, Mendel CM, Bosman ME, Hepple JA, Pym AS, Warren RM, van Helden PD.

J Clin Microbiol. 2014 Nov;52(11):4056-7. doi: 10.1128/JCM.02438-14. Epub 2014 Aug 27.

32.

Genetic profile of Mycobacterium tuberculosis and treatment outcomes in human pulmonary tuberculosis in Tanzania.

Mfinanga SG, Warren RM, Kazwala R, Kahwa A, Kazimoto T, Kimaro G, Mfaume S, Chonde T, Ngadaya E, Egwaga S, Streicher EM, Van Pittius GN, Morkve O, Cleaveland S.

Tanzan J Health Res. 2014 Apr;16(2):58-69.

PMID:
26875299
33.

Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis.

Borrell S, Teo Y, Giardina F, Streicher EM, Klopper M, Feldmann J, Müller B, Victor TC, Gagneux S.

Evol Med Public Health. 2013 Jan;2013(1):65-74. doi: 10.1093/emph/eot003. Epub 2013 Mar 8.

34.

Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa: a cohort study.

Pietersen E, Ignatius E, Streicher EM, Mastrapa B, Padanilam X, Pooran A, Badri M, Lesosky M, van Helden P, Sirgel FA, Warren R, Dheda K.

Lancet. 2014 Apr 5;383(9924):1230-9. doi: 10.1016/S0140-6736(13)62675-6. Epub 2014 Jan 17.

PMID:
24439237
35.

Characterization of W-Beijing isolates of Mycobacterium tuberculosis from the Western Cape.

Shanley CA, Streicher EM, Warren RM, Victor TC, Orme IM.

Vaccine. 2013 Dec 5;31(50):5934-9. doi: 10.1016/j.vaccine.2013.10.044. Epub 2013 Oct 19.

36.

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa.

Müller B, Chihota VN, Pillay M, Klopper M, Streicher EM, Coetzee G, Trollip A, Hayes C, Bosman ME, Gey van Pittius NC, Victor TC, Gagneux S, van Helden PD, Warren RM.

PLoS One. 2013 Aug 23;8(8):e70919. doi: 10.1371/journal.pone.0070919. eCollection 2013.

37.

Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis.

Farhat MR, Shapiro BJ, Kieser KJ, Sultana R, Jacobson KR, Victor TC, Warren RM, Streicher EM, Calver A, Sloutsky A, Kaur D, Posey JE, Plikaytis B, Oggioni MR, Gardy JL, Johnston JC, Rodrigues M, Tang PK, Kato-Maeda M, Borowsky ML, Muddukrishna B, Kreiswirth BN, Kurepina N, Galagan J, Gagneux S, Birren B, Rubin EJ, Lander ES, Sabeti PC, Murray M.

Nat Genet. 2013 Oct;45(10):1183-9. doi: 10.1038/ng.2747. Epub 2013 Sep 1.

38.

Population structure of mixed Mycobacterium tuberculosis infection is strain genotype and culture medium dependent.

Hanekom M, Streicher EM, Van de Berg D, Cox H, McDermid C, Bosman M, Gey van Pittius NC, Victor TC, Kidd M, van Soolingen D, van Helden PD, Warren RM.

PLoS One. 2013 Jul 30;8(7):e70178. doi: 10.1371/journal.pone.0070178. Print 2013.

39.

Emergence and spread of extensively and totally drug-resistant tuberculosis, South Africa.

Klopper M, Warren RM, Hayes C, Gey van Pittius NC, Streicher EM, Müller B, Sirgel FA, Chabula-Nxiweni M, Hoosain E, Coetzee G, David van Helden P, Victor TC, Trollip AP.

Emerg Infect Dis. 2013 Mar;19(3):449-55. doi: 10.3201/EID1903.120246.

40.

embB306 mutations as molecular indicators to predict ethambutol susceptibility in Mycobacterium tuberculosis.

Sirgel FA, Warren RM, Streicher EM, Victor TC, van Helden PD, Böttger EC.

Chemotherapy. 2012;58(5):358-63. doi: 10.1159/000343474. Epub 2012 Nov 17.

41.

Implementation of genotype MTBDRplus reduces time to multidrug-resistant tuberculosis therapy initiation in South Africa.

Jacobson KR, Theron D, Kendall EA, Franke MF, Barnard M, van Helden PD, Victor TC, Streicher EM, Murray MB, Warren RM.

Clin Infect Dis. 2013 Feb;56(4):503-8. doi: 10.1093/cid/cis920. Epub 2012 Oct 22.

42.

Infection of African buffalo (Syncerus caffer) by oryx bacillus, a rare member of the antelope clade of the Mycobacterium tuberculosis complex.

Gey van Pittius NC, Perrett KD, Michel AL, Keet DF, Hlokwe T, Streicher EM, Warren RM, van Helden PD.

J Wildl Dis. 2012 Oct;48(4):849-57. doi: 10.7589/2010-07-178.

PMID:
23060486
43.

gyrA mutations and phenotypic susceptibility levels to ofloxacin and moxifloxacin in clinical isolates of Mycobacterium tuberculosis.

Sirgel FA, Warren RM, Streicher EM, Victor TC, van Helden PD, Böttger EC.

J Antimicrob Chemother. 2012 May;67(5):1088-93. doi: 10.1093/jac/dks033. Epub 2012 Feb 22.

44.

Mycobacterium tuberculosis population structure determines the outcome of genetics-based second-line drug resistance testing.

Streicher EM, Bergval I, Dheda K, Böttger EC, Gey van Pittius NC, Bosman M, Coetzee G, Anthony RM, van Helden PD, Victor TC, Warren RM.

Antimicrob Agents Chemother. 2012 May;56(5):2420-7. doi: 10.1128/AAC.05905-11. Epub 2012 Feb 13.

45.

Rise in rifampicin-monoresistant tuberculosis in Western Cape, South Africa.

Mukinda FK, Theron D, van der Spuy GD, Jacobson KR, Roscher M, Streicher EM, Musekiwa A, Coetzee GJ, Victor TC, Marais BJ, Nachega JB, Warren RM, Schaaf HS.

Int J Tuberc Lung Dis. 2012 Feb;16(2):196-202. doi: 10.5588/ijtld.11.0116.

46.

Population structure of multi- and extensively drug-resistant Mycobacterium tuberculosis strains in South Africa.

Chihota VN, Müller B, Mlambo CK, Pillay M, Tait M, Streicher EM, Marais E, van der Spuy GD, Hanekom M, Coetzee G, Trollip A, Hayes C, Bosman ME, Gey van Pittius NC, Victor TC, van Helden PD, Warren RM.

J Clin Microbiol. 2012 Mar;50(3):995-1002. doi: 10.1128/JCM.05832-11. Epub 2011 Dec 14.

47.

Emergence and treatment of multidrug resistant (MDR) and extensively drug-resistant (XDR) tuberculosis in South Africa.

Streicher EM, Müller B, Chihota V, Mlambo C, Tait M, Pillay M, Trollip A, Hoek KG, Sirgel FA, Gey van Pittius NC, van Helden PD, Victor TC, Warren RM.

Infect Genet Evol. 2012 Jun;12(4):686-94. doi: 10.1016/j.meegid.2011.07.019. Epub 2011 Aug 4. Review.

PMID:
21839855
48.

Treatment outcomes of isoniazid-resistant tuberculosis patients, Western Cape Province, South Africa.

Jacobson KR, Theron D, Victor TC, Streicher EM, Warren RM, Murray MB.

Clin Infect Dis. 2011 Aug;53(4):369-72. doi: 10.1093/cid/cir406.

49.

Mutations in the rrs A1401G gene and phenotypic resistance to amikacin and capreomycin in Mycobacterium tuberculosis.

Sirgel FA, Tait M, Warren RM, Streicher EM, Böttger EC, van Helden PD, Gey van Pittius NC, Coetzee G, Hoosain EY, Chabula-Nxiweni M, Hayes C, Victor TC, Trollip A.

Microb Drug Resist. 2012 Apr;18(2):193-7. doi: 10.1089/mdr.2011.0063. Epub 2011 Jul 6.

50.

Modification of the QuantiFERON-TB Gold (In-Tube) assay for the diagnosis of Mycobacterium bovis infection in African buffaloes (Syncerus caffer).

Parsons SD, Cooper D, McCall AJ, McCall WA, Streicher EM, le Maitre NC, Müller A, Gey van Pittius NC, Warren RM, van Helden PD.

Vet Immunol Immunopathol. 2011 Jul 15;142(1-2):113-8. doi: 10.1016/j.vetimm.2011.04.006. Epub 2011 Apr 20.

PMID:
21561669

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