Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 86

1.

Zika virus causes acute and chronic prostatitis in mice and macaques.

Halabi J, Jagger BW, Salazar V, Winkler ES, White JP, Humphrey PA, Hirsch AJ, Streblow DN, Diamond MS, Moley K.

J Infect Dis. 2019 Oct 16. pii: jiz533. doi: 10.1093/infdis/jiz533. [Epub ahead of print]

PMID:
31616920
2.

Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34+ Hematopoietic Progenitor Cells and Humanized NSG Mice.

Crawford LB, Caposio P, Kreklywich C, Pham AH, Hancock MH, Jones TA, Smith PP, Yurochko AD, Nelson JA, Streblow DN.

MBio. 2019 Aug 20;10(4). pii: e01889-19. doi: 10.1128/mBio.01889-19.

3.

Risk of Zika microcephaly correlates with features of maternal antibodies.

Robbiani DF, Olsen PC, Costa F, Wang Q, Oliveira TY, Nery N Jr, Aromolaran A, do Rosário MS, Sacramento GA, Cruz JS, Khouri R, Wunder EA Jr, Mattos A, de Paula Freitas B, Sarno M, Archanjo G, Daltro D, Carvalho GBS, Pimentel K, de Siqueira IC, de Almeida JRM, Henriques DF, Lima JA, Vasconcelos PFC, Schaefer-Babajew D, Azzopardi SA, Bozzacco L, Gazumyan A, Belfort R Jr, Alcântara AP, Carvalho G, Moreira L, Araujo K, Reis MG, Keesler RI, Coffey LL, Tisoncik-Go J, Gale M Jr, Rajagopal L, Adams Waldorf KM, Dudley DM, Simmons HA, Mejia A, O'Connor DH, Steinbach RJ, Haese N, Smith J, Lewis A, Colgin L, Roberts V, Frias A, Kelleher M, Hirsch A, Streblow DN, Rice CM, MacDonald MR, de Almeida ARP, Van Rompay KKA, Ko AI, Nussenzweig MC.

J Exp Med. 2019 Oct 7;216(10):2302-2315. doi: 10.1084/jem.20191061. Epub 2019 Aug 14.

4.

Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity.

Marshall EE, Malouli D, Hansen SG, Gilbride RM, Hughes CM, Ventura AB, Ainslie E, Selseth AN, Ford JC, Burke D, Kreklywich CN, Womack J, Legasse AW, Axthelm MK, Kahl C, Streblow D, Edlefsen PT, Picker LJ, Früh K.

Sci Transl Med. 2019 Jul 17;11(501). pii: eaaw2603. doi: 10.1126/scitranslmed.aaw2603.

PMID:
31316006
5.

Studies on Dibenzylamines as Inhibitors of Venezuelan Equine Encephalitis Virus.

Nguyen TH, Haese NN, Madadi N, Sarkar S, Bonin K, Streblow CE, Taft-Benz S, Tower NA, Rasmussen L, Bostwick R, Augelli-Szafran CE, Suto MJ, Morrison TE, DeFilippis V, Heise MT, Streblow DN, Pathak AK.

ACS Infect Dis. 2019 Jul 11. doi: 10.1021/acsinfecdis.9b00035. [Epub ahead of print]

PMID:
31257853
6.

Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs.

Broeckel R, Sarkar S, May NA, Totonchy J, Kreklywich CN, Smith P, Graves L, DeFilippis VR, Heise MT, Morrison TE, Moorman N, Streblow DN.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02325-18. doi: 10.1128/AAC.02325-18. Print 2019 Apr.

7.

Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome.

Botto S, Abraham J, Mizuno N, Pryke K, Gall B, Landais I, Streblow DN, Fruh KJ, DeFilippis VR.

MBio. 2019 Feb 12;10(1). pii: e02510-18. doi: 10.1128/mBio.02510-18.

8.

HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission.

Vanarsdall AL, Chin AL, Liu J, Jardetzky TS, Mudd JO, Orloff SL, Streblow D, Mussi-Pinhata MM, Yamamoto AY, Duarte G, Britt WJ, Johnson DC.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3728-3733. doi: 10.1073/pnas.1814835116. Epub 2019 Feb 7.

9.

Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates.

Dudley DM, Van Rompay KK, Coffey LL, Ardeshir A, Keesler RI, Bliss-Moreau E, Grigsby PL, Steinbach RJ, Hirsch AJ, MacAllister RP, Pecoraro HL, Colgin LM, Hodge T, Streblow DN, Tardif S, Patterson JL, Tamhankar M, Seferovic M, Aagaard KM, Martín CS, Chiu CY, Panganiban AT, Veazey RS, Wang X, Maness NJ, Gilbert MH, Bohm RP, Adams Waldorf KM, Gale M Jr, Rajagopal L, Hotchkiss CE, Mohr EL, Capuano SV 3rd, Simmons HA, Mejia A, Friedrich TC, Golos TG, O'Connor DH.

Nat Med. 2018 Aug;24(8):1104-1107. doi: 10.1038/s41591-018-0088-5. Epub 2018 Jul 2.

10.

In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain.

Cloarec R, Bauer S, Teissier N, Schaller F, Luche H, Courtens S, Salmi M, Pauly V, Bois E, Pallesi-Pocachard E, Buhler E, Michel FJ, Gressens P, Malissen M, Stamminger T, Streblow DN, Bruneau N, Szepetowski P.

Front Cell Neurosci. 2018 Mar 6;12:55. doi: 10.3389/fncel.2018.00055. eCollection 2018.

11.

Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology.

Hirsch AJ, Roberts VHJ, Grigsby PL, Haese N, Schabel MC, Wang X, Lo JO, Liu Z, Kroenke CD, Smith JL, Kelleher M, Broeckel R, Kreklywich CN, Parkins CJ, Denton M, Smith P, DeFilippis V, Messer W, Nelson JA, Hennebold JD, Grafe M, Colgin L, Lewis A, Ducore R, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Moses AV, Morgan TK, Frias AE, Streblow DN.

Nat Commun. 2018 Jan 17;9(1):263. doi: 10.1038/s41467-017-02499-9.

12.

Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway.

Gall B, Pryke K, Abraham J, Mizuno N, Botto S, Sali TM, Broeckel R, Haese N, Nilsen A, Placzek A, Morrison T, Heise M, Streblow D, DeFilippis V.

J Virol. 2018 Feb 26;92(6). pii: e01913-17. doi: 10.1128/JVI.01913-17. Print 2018 Mar 15.

13.

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.

Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE Jr, Diamond MS, Streblow DN.

PLoS Negl Trop Dis. 2017 Jun 19;11(6):e0005637. doi: 10.1371/journal.pntd.0005637. eCollection 2017 Jun.

14.

A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.

Pryke KM, Abraham J, Sali TM, Gall BJ, Archer I, Liu A, Bambina S, Baird J, Gough M, Chakhtoura M, Haddad EK, Kirby IT, Nilsen A, Streblow DN, Hirsch AJ, Smith JL, DeFilippis VR.

MBio. 2017 May 2;8(3). pii: e00452-17. doi: 10.1128/mBio.00452-17.

15.

Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.

Crawford LB, Tempel R, Streblow DN, Kreklywich C, Smith P, Picker LJ, Nelson JA, Caposio P.

Sci Rep. 2017 Apr 20;7(1):937. doi: 10.1038/s41598-017-01051-5.

16.

Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.

Hirsch AJ, Smith JL, Haese NN, Broeckel RM, Parkins CJ, Kreklywich C, DeFilippis VR, Denton M, Smith PP, Messer WB, Colgin LM, Ducore RM, Grigsby PL, Hennebold JD, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Wiley CA, Nelson JA, Streblow DN.

PLoS Pathog. 2017 Apr 5;13(4):e1006317. doi: 10.1371/journal.ppat.1006317. eCollection 2017 Apr.

17.

Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.

Hirsch AJ, Smith JL, Haese NN, Broeckel RM, Parkins CJ, Kreklywich C, DeFilippis VR, Denton M, Smith PP, Messer WB, Colgin LM, Ducore RM, Grigsby PL, Hennebold JD, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Wiley CA, Nelson JA, Streblow DN.

PLoS Pathog. 2017 Mar 9;13(3):e1006219. doi: 10.1371/journal.ppat.1006219. eCollection 2017 Mar. Erratum in: PLoS Pathog. 2017 Apr 5;13(4):e1006317.

18.

Animal Models of Chikungunya Virus Infection and Disease.

Haese NN, Broeckel RM, Hawman DW, Heise MT, Morrison TE, Streblow DN.

J Infect Dis. 2016 Dec 15;214(suppl 5):S482-S487. Review.

19.

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months.

Pelliccia M, Andreozzi P, Paulose J, D'Alicarnasso M, Cagno V, Donalisio M, Civra A, Broeckel RM, Haese N, Jacob Silva P, Carney RP, Marjomäki V, Streblow DN, Lembo D, Stellacci F, Vitelli V, Krol S.

Nat Commun. 2016 Nov 30;7:13520. doi: 10.1038/ncomms13520.

20.

Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques.

Burwitz BJ, Malouli D, Bimber BN, Reed JS, Ventura AB, Hancock MH, Uebelhoer LS, Bhusari A, Hammond KB, Espinosa Trethewy RG, Klug A, Legasse AW, Axthelm MK, Nelson JA, Park BS, Streblow DN, Hansen SG, Picker LJ, Früh K, Sacha JB.

PLoS Pathog. 2016 Nov 9;12(11):e1006014. doi: 10.1371/journal.ppat.1006014. eCollection 2016 Nov.

21.

Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus.

Uhrlaub JL, Pulko V, DeFilippis VR, Broeckel R, Streblow DN, Coleman GD, Park BS, Lindo JF, Vickers I, Anzinger JJ, Nikolich-Žugich J.

PLoS Pathog. 2016 Oct 13;12(10):e1005891. doi: 10.1371/journal.ppat.1005891. eCollection 2016 Oct.

22.

Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation.

Cloarec R, Bauer S, Luche H, Buhler E, Pallesi-Pocachard E, Salmi M, Courtens S, Massacrier A, Grenot P, Teissier N, Watrin F, Schaller F, Adle-Biassette H, Gressens P, Malissen M, Stamminger T, Streblow DN, Bruneau N, Szepetowski P.

PLoS One. 2016 Jul 29;11(7):e0160176. doi: 10.1371/journal.pone.0160176. eCollection 2016.

23.

Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency.

Caviness K, Bughio F, Crawford LB, Streblow DN, Nelson JA, Caposio P, Goodrum F.

MBio. 2016 Mar 1;7(2):e01986. doi: 10.1128/mBio.01986-15.

24.

Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses.

Sali TM, Pryke KM, Abraham J, Liu A, Archer I, Broeckel R, Staverosky JA, Smith JL, Al-Shammari A, Amsler L, Sheridan K, Nilsen A, Streblow DN, DeFilippis VR.

PLoS Pathog. 2015 Dec 8;11(12):e1005324. doi: 10.1371/journal.ppat.1005324. eCollection 2015 Dec.

25.

Nonhuman Primate Models of Chikungunya Virus Infection and Disease (CHIKV NHP Model).

Broeckel R, Haese N, Messaoudi I, Streblow DN.

Pathogens. 2015 Sep 16;4(3):662-81. doi: 10.3390/pathogens4030662. Review.

26.

Humanized mouse models of human cytomegalovirus infection.

Crawford LB, Streblow DN, Hakki M, Nelson JA, Caposio P.

Curr Opin Virol. 2015 Aug;13:86-92. doi: 10.1016/j.coviro.2015.06.006. Epub 2015 Jun 25. Review.

27.

Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists.

Chiang C, Beljanski V, Yin K, Olagnier D, Ben Yebdri F, Steel C, Goulet ML, DeFilippis VR, Streblow DN, Haddad EK, Trautmann L, Ross T, Lin R, Hiscott J.

J Virol. 2015 Aug;89(15):8011-25. doi: 10.1128/JVI.00845-15. Epub 2015 May 27.

28.

Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway.

Landais I, Pelton C, Streblow D, DeFilippis V, McWeeney S, Nelson JA.

PLoS Pathog. 2015 May 8;11(5):e1004881. doi: 10.1371/journal.ppat.1004881. eCollection 2015 May.

29.

Rat Cytomegalovirus Vaccine Prevents Accelerated Chronic Rejection in CMV-Naïve Recipients of Infected Donor Allograft Hearts.

Streblow DN, Hwee YK, Kreklywich CN, Andoh T, Denton M, Smith P, Hart E, Broekel R, Pallett C, Rogers K, Streblow AD, Chuop M, Perry A, Slifka M, Messaoudi I, Orloff SL.

Am J Transplant. 2015 Jul;15(7):1805-16. doi: 10.1111/ajt.13188. Epub 2015 Mar 12.

30.

Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes.

Pal P, Fox JM, Hawman DW, Huang YJ, Messaoudi I, Kreklywich C, Denton M, Legasse AW, Smith PP, Johnson S, Axthelm MK, Vanlandingham DL, Streblow DN, Higgs S, Morrison TE, Diamond MS.

J Virol. 2014 Aug;88(15):8213-26. doi: 10.1128/JVI.01032-14. Epub 2014 May 14.

31.

Cytomegalovirus pp65 limits dissemination but is dispensable for persistence.

Malouli D, Hansen SG, Nakayasu ES, Marshall EE, Hughes CM, Ventura AB, Gilbride RM, Lewis MS, Xu G, Kreklywich C, Whizin N, Fischer M, Legasse AW, Viswanathan K, Siess D, Camp DG 2nd, Axthelm MK, Kahl C, DeFilippis VR, Smith RD, Streblow DN, Picker LJ, Früh K.

J Clin Invest. 2014 May;124(5):1928-44. Epub 2014 Apr 1.

32.

Fluorescence-based laser capture microscopy technology facilitates identification of critical in vivo cytomegalovirus transcriptional programs.

Kreklywich CN, Smith PP, Jones CB, Cornea A, Orloff SL, Streblow DN.

Methods Mol Biol. 2014;1119:217-37. doi: 10.1007/978-1-62703-788-4_13.

33.

Human cytomegalovirus induces upregulation of arginase II: possible implications for vasculopathies.

Yaiw KC, Mohammad AA, Taher C, Wilhelmi V, Davoudi B, Strååt K, Assinger A, Ovchinnikova O, Shlyakhto E, Rahbar A, Koutonguk O, Religa P, Butler L, Khan Z, Streblow D, Pernow J, Söderberg-Nauclér C.

Basic Res Cardiol. 2014 Mar;109(2):401. doi: 10.1007/s00395-014-0401-5. Epub 2014 Jan 19.

PMID:
24442486
34.

HCMV infection of humanized mice after transplantation of G-CSF-mobilized peripheral blood stem cells from HCMV-seropositive donors.

Hakki M, Goldman DC, Streblow DN, Hamlin KL, Krekylwich CN, Fleming WH, Nelson JA.

Biol Blood Marrow Transplant. 2014 Jan;20(1):132-5. doi: 10.1016/j.bbmt.2013.10.019. Epub 2013 Oct 23.

35.

Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity.

Messaoudi I, Vomaske J, Totonchy T, Kreklywich CN, Haberthur K, Springgay L, Brien JD, Diamond MS, Defilippis VR, Streblow DN.

PLoS Negl Trop Dis. 2013 Jul 25;7(7):e2343. doi: 10.1371/journal.pntd.0002343. Print 2013.

36.

Cytomegalovirus CC chemokine promotes immune cell migration.

Vomaske J, Denton M, Kreklywich C, Andoh T, Osborn JM, Chen D, Messaoudi I, Orloff SL, Streblow DN.

J Virol. 2012 Nov;86(21):11833-44. doi: 10.1128/JVI.00452-12. Epub 2012 Aug 22.

37.

A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection.

Umashankar M, Petrucelli A, Cicchini L, Caposio P, Kreklywich CN, Rak M, Bughio F, Goldman DC, Hamlin KL, Nelson JA, Fleming WH, Streblow DN, Goodrum F.

PLoS Pathog. 2011 Dec;7(12):e1002444. doi: 10.1371/journal.ppat.1002444. Epub 2011 Dec 29.

38.

Simian varicella virus gene expression during acute and latent infection of rhesus macaques.

Meyer C, Kerns A, Barron A, Kreklywich C, Streblow DN, Messaoudi I.

J Neurovirol. 2011 Dec;17(6):600-12. doi: 10.1007/s13365-011-0057-y. Epub 2011 Nov 4.

39.

Cytomegalovirus latency promotes cardiac lymphoid neogenesis and accelerated allograft rejection in CMV naïve recipients.

Orloff SL, Hwee YK, Kreklywich C, Andoh TF, Hart E, Smith PA, Messaoudi I, Streblow DN.

Am J Transplant. 2011 Jan;11(1):45-55. doi: 10.1111/j.1600-6143.2010.03365.x.

40.

Cytomegalovirus microRNA expression is tissue specific and is associated with persistence.

Meyer C, Grey F, Kreklywich CN, Andoh TF, Tirabassi RS, Orloff SL, Streblow DN.

J Virol. 2011 Jan;85(1):378-89. doi: 10.1128/JVI.01900-10. Epub 2010 Oct 27.

41.

Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.

White LK, Sali T, Alvarado D, Gatti E, Pierre P, Streblow D, Defilippis VR.

J Virol. 2011 Jan;85(1):606-20. doi: 10.1128/JVI.00767-10. Epub 2010 Oct 20.

42.

IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin.

Botto S, Streblow DN, DeFilippis V, White L, Kreklywich CN, Smith PP, Caposio P.

Blood. 2011 Jan 6;117(1):352-61. doi: 10.1182/blood-2010-06-291245. Epub 2010 Oct 7.

43.

The role of cytomegalovirus in angiogenesis.

Caposio P, Orloff SL, Streblow DN.

Virus Res. 2011 May;157(2):204-11. doi: 10.1016/j.virusres.2010.09.011. Epub 2010 Oct 1. Review.

44.

Polymeric PARACEST MRI contrast agents as potential reporters for gene therapy.

Wu Y, Carney CE, Denton M, Hart E, Zhao P, Streblow DN, Sherry AD, Woods M.

Org Biomol Chem. 2010 Dec 7;8(23):5333-8. doi: 10.1039/c0ob00087f. Epub 2010 Sep 16.

45.

Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model.

Smith MS, Goldman DC, Bailey AS, Pfaffle DL, Kreklywich CN, Spencer DB, Othieno FA, Streblow DN, Garcia JV, Fleming WH, Nelson JA.

Cell Host Microbe. 2010 Sep 16;8(3):284-91. doi: 10.1016/j.chom.2010.08.001.

46.

HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase.

Vomaske J, Varnum S, Melnychuk R, Smith P, Pasa-Tolic L, Shutthanandan JI, Streblow DN.

Herpesviridae. 2010 Dec 7;1(1):2. doi: 10.1186/2042-4280-1-2.

47.

Human Cytomegalovirus US28: a functionally selective chemokine binding receptor.

Vomaske J, Nelson JA, Streblow DN.

Infect Disord Drug Targets. 2009 Nov;9(5):548-56. Review.

48.

Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells.

Baca Jones CC, Kreklywich CN, Messaoudi I, Vomaske J, McCartney E, Orloff SL, Nelson JA, Streblow DN.

Virology. 2009 May 25;388(1):78-90. doi: 10.1016/j.virol.2009.02.050. Epub 2009 Apr 5.

49.

Differential ligand binding to a human cytomegalovirus chemokine receptor determines cell type-specific motility.

Vomaske J, Melnychuk RM, Smith PP, Powell J, Hall L, DeFilippis V, Früh K, Smit M, Schlaepfer DD, Nelson JA, Streblow DN.

PLoS Pathog. 2009 Feb;5(2):e1000304. doi: 10.1371/journal.ppat.1000304. Epub 2009 Feb 20.

50.

Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing.

Streblow DN, Dumortier J, Moses AV, Orloff SL, Nelson JA.

Curr Top Microbiol Immunol. 2008;325:397-415. Review.

Supplemental Content

Loading ...
Support Center