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Targeted deletion of PD-1 in myeloid cells induces antitumor immunity.

Strauss L, Mahmoud MAA, Weaver JD, Tijaro-Ovalle NM, Christofides A, Wang Q, Pal R, Yuan M, Asara J, Patsoukis N, Boussiotis VA.

Sci Immunol. 2020 Jan 3;5(43). pii: eaay1863. doi: 10.1126/sciimmunol.aay1863.


Phosphorylation of PD-1-Y248 is a marker of PD-1-mediated inhibitory function in human T cells.

Bardhan K, Aksoylar HI, Bourgeois TL, Strauss L, Weaver JD, Delcuze B, Charest A, Patsoukis N, Boussiotis VA.

Sci Rep. 2019 Nov 21;9(1):17252. doi: 10.1038/s41598-019-53463-0.


Pediatric Migraine Action Plan (PedMAP).

Turner SB, Rende EK, Pezzuto T, Weaver S, Henderlong-Kropp A, Greene KA, Bicknese AR, Dilts JJ, Gautreaux J, Victorio MCC, Strauss LD, Lagman-Bartolome AM, Szperka CL, Yonker M, Hershey AD, Gelfand AA.

Headache. 2019 Nov;59(10):1871-1873. doi: 10.1111/head.13681. No abstract available.


Randomized phase-II evaluation of letrozole plus dasatinib in hormone receptor positive metastatic breast cancer patients.

Paul D, Vukelja SJ, Ann Holmes F, Blum JL, McIntyre KJ, Lindquist DL, Osborne CR, Sanchez IJ, Goldschmidt JH, Wang Y, Asmar L, Strauss L, O'Shaughnessy J.

NPJ Breast Cancer. 2019 Oct 28;5:36. doi: 10.1038/s41523-019-0132-8. eCollection 2019.


Sorafenib Induces Pyroptosis in Macrophages and Triggers Natural Killer Cell-Mediated Cytotoxicity Against Hepatocellular Carcinoma.

Hage C, Hoves S, Strauss L, Bissinger S, Prinz Y, Pöschinger T, Kiessling F, Ries CH.

Hepatology. 2019 Oct;70(4):1280-1297. doi: 10.1002/hep.30666. Epub 2019 May 21.


Fleshy Mass Passed Vaginally by a Young Woman.

Strauss L.

Am Fam Physician. 2018 Oct 1;98(7):449-450. No abstract available.


Long-term efficacy and safety of dasatinib in patients with chronic myeloid leukemia in accelerated phase who are resistant to or intolerant of imatinib.

Ottmann O, Saglio G, Apperley JF, Arthur C, Bullorsky E, Charbonnier A, Dipersio JF, Kantarjian H, Khoury HJ, Kim DW, Healey D, Strauss L, Cortes JE.

Blood Cancer J. 2018 Sep 3;8(9):88. doi: 10.1038/s41408-018-0122-3. No abstract available.


Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy.

Le Bourgeois T, Strauss L, Aksoylar HI, Daneshmandi S, Seth P, Patsoukis N, Boussiotis VA.

Front Oncol. 2018 Aug 3;8:237. doi: 10.3389/fonc.2018.00237. eCollection 2018. Review.


Subdural Hygroma: A Case Report of an Uncommon Persistence of Elevated Intracranial Pressure.

Rosenthal S, Curry C, Geer C, Martin T, Zapadka M, Grefe A, Strauss L.

Headache. 2019 Mar;59(3):450-451. doi: 10.1111/head.13360. Epub 2018 Aug 9. No abstract available.


Optimization of combination therapy for chronic myeloid leukemia with dosing constraints.

Moore H, Strauss L, Ledzewicz U.

J Math Biol. 2018 Nov;77(5):1533-1561. doi: 10.1007/s00285-018-1262-6. Epub 2018 Jul 10.


Publisher Correction: Feeling stressed? It might be your T cells.

Strauss L, Patsoukis N, Boussiotis VA.

Nat Immunol. 2018 Sep;19(9):1037. doi: 10.1038/s41590-018-0140-0.


NLRP3 in somatic non-immune cells of rodent and primate testes.

Walenta L, Schmid N, Schwarzer JU, Köhn FM, Urbanski HF, Behr R, Strauss L, Poutanen M, Mayerhofer A.

Reproduction. 2018 Sep;156(3):231-238. doi: 10.1530/REP-18-0111. Epub 2018 Jun 15.


Insights into the role of androgen receptor in human testicular peritubular cells.

Mayer C, Adam M, Walenta L, Schmid N, Heikelä H, Schubert K, Flenkenthaler F, Dietrich KG, Gruschka S, Arnold GJ, Fröhlich T, Schwarzer JU, Köhn FM, Strauss L, Welter H, Poutanen M, Mayerhofer A.

Andrology. 2018 Sep;6(5):756-765. doi: 10.1111/andr.12509. Epub 2018 Jun 5.


Introducing the Migraine Action Plan.

Peretz AM, Minen MT, Cowan R, Strauss LD.

Headache. 2018 Feb;58(2):195. doi: 10.1111/head.13256. No abstract available.


Migraine Action Plan (MAP).

Peretz AM, Minen MT, Cowan R, Strauss LD.

Headache. 2018 Feb;58(2):355-356. doi: 10.1111/head.13255. No abstract available.


Hydroxysteroid (17β) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in mice.

Adam M, Heikelä H, Sobolewski C, Portius D, Mäki-Jouppila J, Mehmood A, Adhikari P, Esposito I, Elo LL, Zhang FP, Ruohonen ST, Strauss L, Foti M, Poutanen M.

FASEB J. 2018 Jun;32(6):3434-3447. doi: 10.1096/fj.201700914R. Epub 2018 Jan 31.


The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer.

Kemiläinen H, Huhtinen K, Auranen A, Carpén O, Strauss L, Poutanen M.

Oncology. 2018;94(4):233-242. doi: 10.1159/000485624. Epub 2018 Jan 12.


Origin, evolution, and global transmission of community-acquired Staphylococcus aureus ST8.

Strauß L, Stegger M, Akpaka PE, Alabi A, Breurec S, Coombs G, Egyir B, Larsen AR, Laurent F, Monecke S, Peters G, Skov R, Strommenger B, Vandenesch F, Schaumburg F, Mellmann A.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10596-E10604. doi: 10.1073/pnas.1702472114. Epub 2017 Nov 20.


Feeling stressed? It might be your T cells.

Strauss L, Patsoukis N, Boussiotis VA.

Nat Immunol. 2017 Nov 16;18(12):1281-1283. doi: 10.1038/ni.3872. No abstract available. Erratum in: Nat Immunol. 2018 Sep;19(9):1037.


Nivolumab with or without ipilimumab in patients with recurrent glioblastoma: results from exploratory phase I cohorts of CheckMate 143.

Omuro A, Vlahovic G, Lim M, Sahebjam S, Baehring J, Cloughesy T, Voloschin A, Ramkissoon SH, Ligon KL, Latek R, Zwirtes R, Strauss L, Paliwal P, Harbison CT, Reardon DA, Sampson JH.

Neuro Oncol. 2018 Apr 9;20(5):674-686. doi: 10.1093/neuonc/nox208.


Incidental Findings and Normal Anatomical Variants on Brain MRI in Children for Primary Headaches.

Strauss LD, Cavanaugh BA, Yun ES, Evans RW.

Headache. 2017 Nov;57(10):1601-1609. doi: 10.1111/head.13221. Epub 2017 Oct 6. Review.


The Impact of the Staphylococcus aureus Virulome on Infection in a Developing Country: A Cohort Study.

Lebughe M, Phaku P, Niemann S, Mumba D, Peters G, Muyembe-Tamfum JJ, Mellmann A, Strauß L, Schaumburg F.

Front Microbiol. 2017 Aug 29;8:1662. doi: 10.3389/fmicb.2017.01662. eCollection 2017.


The adaptor molecule RIAM integrates signaling events critical for integrin-mediated control of immune function and cancer progression.

Patsoukis N, Bardhan K, Weaver JD, Sari D, Torres-Gomez A, Li L, Strauss L, Lafuente EM, Boussiotis VA.

Sci Signal. 2017 Aug 22;10(493). pii: eaam8298. doi: 10.1126/scisignal.aam8298. Review.


Patterns of NSAIDs Use and Their Association with Other Analgesic Use in CKD.

Zhan M, St Peter WL, Doerfler RM, Woods CM, Blumenthal JB, Diamantidis CJ, Hsu CY, Lash JP, Lustigova E, Mahone EB, Ojo AO, Slaven A, Strauss L, Taliercio JJ, Winkelmayer WC, Xie D, Fink JC; Chronic Renal Insufficiency Cohort (CRIC) Study Investigators.

Clin J Am Soc Nephrol. 2017 Nov 7;12(11):1778-1786. doi: 10.2215/CJN.12311216. Epub 2017 Aug 15.


Radiation-agent combinations for glioblastoma: challenges in drug development and future considerations.

Kunos CA, Galanis E, Buchsbaum J, Shi Q, Strauss LC, Coleman CN, Ahmed MM.

J Neurooncol. 2017 Sep;134(3):551-557. doi: 10.1007/s11060-017-2458-0. Epub 2017 May 30. Review.


A unique profilin-actin interface is important for malaria parasite motility.

Moreau CA, Bhargav SP, Kumar H, Quadt KA, Piirainen H, Strauss L, Kehrer J, Streichfuss M, Spatz JP, Wade RC, Kursula I, Frischknecht F.

PLoS Pathog. 2017 May 26;13(5):e1006412. doi: 10.1371/journal.ppat.1006412. eCollection 2017 May.


Diagnostic and Therapeutic Management of a First Unprovoked Seizure in Children and Adolescents With a Focus on the Revised Diagnostic Criteria for Epilepsy.

Sansevere AJ, Avalone J, Strauss LD, Patel AA, Pinto A, Ramachandran M, Fernandez IS, Bergin AM, Kimia A, Pearl PL, Loddenkemper T.

J Child Neurol. 2017 Jul;32(8):774-788. doi: 10.1177/0883073817706028. Epub 2017 May 14. Review.


Metabolic regulation of suppressive myeloid cells in cancer.

Sica A, Strauss L, Consonni FM, Travelli C, Genazzani A, Porta C.

Cytokine Growth Factor Rev. 2017 Jun;35:27-35. doi: 10.1016/j.cytogfr.2017.05.002. Epub 2017 May 3. Review.


Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses.

Patsoukis N, Weaver JD, Strauss L, Herbel C, Seth P, Boussiotis VA.

Front Immunol. 2017 Apr 11;8:330. doi: 10.3389/fimmu.2017.00330. eCollection 2017. Review.


Community-Associated Staphylococcus aureus from Sub-Saharan Africa and Germany: A Cross-Sectional Geographic Correlation Study.

Ruffing U, Alabi A, Kazimoto T, Vubil DC, Akulenko R, Abdulla S, Alonso P, Bischoff M, Germann A, Grobusch MP, Helms V, Hoffmann J, Kern WV, Kremsner PG, Mandomando I, Mellmann A, Peters G, Schaumburg F, Schubert S, Strauß L, Tanner M, Briesen HV, Wende L, Müller LV, Herrmann M.

Sci Rep. 2017 Mar 13;7(1):154. doi: 10.1038/s41598-017-00214-8.


Energy metabolism drives myeloid-derived suppressor cell differentiation and functions in pathology.

Sica A, Strauss L.

J Leukoc Biol. 2017 Aug;102(2):325-334. doi: 10.1189/jlb.4MR1116-476R. Epub 2017 Feb 21. Review.


Loss of executive function after dialysis initiation in adults with chronic kidney disease.

Kurella Tamura M, Vittinghoff E, Hsu CY, Tam K, Seliger SL, Sozio S, Fischer M, Chen J, Lustigova E, Strauss L, Deo R, Go AS, Yaffe K; CRIC Study Investigators.

Kidney Int. 2017 Apr;91(4):948-953. doi: 10.1016/j.kint.2016.11.015. Epub 2017 Jan 27.


Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study.

Vavricka S, Ruiz PA, Scharl S, Biedermann L, Scharl M, de Vallière C, Lundby C, Wenger RH, Held L, Merz TM, Gassmann M, Lutz T, Kunz A, Bron D, Fontana A, Strauss L, Weber A, Fried M, Rogler G, Zeitz J.

BMJ Open. 2017 Jan 5;7(1):e013477. doi: 10.1136/bmjopen-2016-013477.


Phase 2 placebo-controlled, double-blind trial of dasatinib added to gemcitabine for patients with locally-advanced pancreatic cancer.

Evans TRJ, Van Cutsem E, Moore MJ, Bazin IS, Rosemurgy A, Bodoky G, Deplanque G, Harrison M, Melichar B, Pezet D, Elekes A, Rock E, Lin C, Strauss L, O'Dwyer PJ.

Ann Oncol. 2017 Feb 1;28(2):354-361. doi: 10.1093/annonc/mdw607.


Sterile inflammation as a factor in human male infertility: Involvement of Toll like receptor 2, biglycan and peritubular cells.

Mayer C, Adam M, Glashauser L, Dietrich K, Schwarzer JU, Köhn FM, Strauss L, Welter H, Poutanen M, Mayerhofer A.

Sci Rep. 2016 Nov 16;6:37128. doi: 10.1038/srep37128.


The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of Fertility.

Kemiläinen H, Adam M, Mäki-Jouppila J, Damdimopoulou P, Damdimopoulos AE, Kere J, Hovatta O, Laajala TD, Aittokallio T, Adamski J, Ryberg H, Ohlsson C, Strauss L, Poutanen M.

Endocrinology. 2016 Oct;157(10):3719-3730. Epub 2016 Aug 4.


From pilot fish to analyst: Finding a path between symbiotic and autistic defences.

Strauss LV.

Int J Psychoanal. 2016 Dec;97(6):1521-1545. doi: 10.1111/1745-8315.12545. Epub 2016 Jul 20.


Unveiling the molecular basis of antimicrobial resistance in Staphylococcus aureus from the Democratic Republic of the Congo using whole genome sequencing.

Phaku P, Lebughe M, Strauß L, Peters G, Herrmann M, Mumba D, Mellmann A, Muyembe-Tamfum JJ, Schaumburg F.

Clin Microbiol Infect. 2016 Jul;22(7):644.e1-5. doi: 10.1016/j.cmi.2016.04.009. Epub 2016 Apr 19.


Turbulence in breaking mountain waves and atmospheric rotors estimated from airborne in situ and Doppler radar measurements.

Strauss L, Serafin S, Haimov S, Grubišić V.

Q J R Meteorol Soc. 2015 Oct;141(693):3207-3225. Epub 2015 Sep 24.


Atrial Fibrillation and Risk of ESRD in Adults with CKD.

Bansal N, Xie D, Tao K, Chen J, Deo R, Horwitz E, Hsu CY, Kallem RK, Keane MG, Lora CM, Raj D, Soliman EZ, Strauss L, Wolf M, Go AS; CRIC Study.

Clin J Am Soc Nephrol. 2016 Jul 7;11(7):1189-96. doi: 10.2215/CJN.10921015. Epub 2016 Apr 12.


Managing Migraine During Pregnancy and Lactation.

Wells RE, Turner DP, Lee M, Bishop L, Strauss L.

Curr Neurol Neurosci Rep. 2016 Apr;16(4):40. doi: 10.1007/s11910-016-0634-9. Review.


Detecting Staphylococcus aureus Virulence and Resistance Genes: a Comparison of Whole-Genome Sequencing and DNA Microarray Technology.

Strauß L, Ruffing U, Abdulla S, Alabi A, Akulenko R, Garrine M, Germann A, Grobusch MP, Helms V, Herrmann M, Kazimoto T, Kern W, Mandomando I, Peters G, Schaumburg F, von Müller L, Mellmann A.

J Clin Microbiol. 2016 Apr;54(4):1008-16. doi: 10.1128/JCM.03022-15. Epub 2016 Jan 27.


Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse.

Vehmas AP, Adam M, Laajala TD, Kastenmüller G, Prehn C, Rozman J, Ohlsson C, Fuchs H, Hrabě de Angelis M, Gailus-Durner V, Elo LL, Aittokallio T, Adamski J, Corthals G, Poutanen M, Strauss L.

J Proteomics. 2016 Feb 5;133:66-75. doi: 10.1016/j.jprot.2015.12.009. Epub 2015 Dec 9.


Traditional and non-traditional risk factors for incident peripheral arterial disease among patients with chronic kidney disease.

Chen J, Mohler ER, Xie D, Shlipak M, Townsend RR, Appel LJ, Ojo A, Schreiber M, Nessel L, Zhang X, Raj D, Strauss L, Lora CM, Rahman M, Hamm LL, He J; CRIC Study Investigators.

Nephrol Dial Transplant. 2016 Jul;31(7):1145-51. doi: 10.1093/ndt/gfv418. Epub 2015 Dec 18.


Optimization of Statistical Methods Impact on Quantitative Proteomics Data.

Pursiheimo A, Vehmas AP, Afzal S, Suomi T, Chand T, Strauss L, Poutanen M, Rokka A, Corthals GL, Elo LL.

J Proteome Res. 2015 Oct 2;14(10):4118-26. doi: 10.1021/acs.jproteome.5b00183. Epub 2015 Sep 8.


RORC1 Regulates Tumor-Promoting "Emergency" Granulo-Monocytopoiesis.

Strauss L, Sangaletti S, Consonni FM, Szebeni G, Morlacchi S, Totaro MG, Porta C, Anselmo A, Tartari S, Doni A, Zitelli F, Tripodo C, Colombo MP, Sica A.

Cancer Cell. 2015 Aug 10;28(2):253-69. doi: 10.1016/j.ccell.2015.07.006.


New Investigator and Trainee Task Force Survey on the Recruitment and Retention of Headache Specialists.

Minen MT, Monteith T, Strauss LD, Starling A.

Headache. 2015 Sep;55(8):1092-101. doi: 10.1111/head.12623. Epub 2015 Aug 3.


Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients.

König K, Peifer M, Fassunke J, Ihle MA, Künstlinger H, Heydt C, Stamm K, Ueckeroth F, Vollbrecht C, Bos M, Gardizi M, Scheffler M, Nogova L, Leenders F, Albus K, Meder L, Becker K, Florin A, Rommerscheidt-Fuss U, Altmüller J, Kloth M, Nürnberg P, Henkel T, Bikár SE, Sos ML, Geese WJ, Strauss L, Ko YD, Gerigk U, Odenthal M, Zander T, Wolf J, Merkelbach-Bruse S, Buettner R, Heukamp LC.

J Thorac Oncol. 2015 Jul;10(7):1049-57. doi: 10.1097/JTO.0000000000000570.


Weight gain and inflammation regulate aromatase expression in male adipose tissue, as evidenced by reporter gene activity.

Polari L, Yatkin E, Martínez Chacón MG, Ahotupa M, Smeds A, Strauss L, Zhang F, Poutanen M, Saarinen N, Mäkelä SI.

Mol Cell Endocrinol. 2015 Sep 5;412:123-30. doi: 10.1016/j.mce.2015.06.002. Epub 2015 Jun 6.


Neutralization of colony-stimulating factor 1 receptor prevents sickness behavior syndrome by reprogramming inflammatory monocytes to produce IL-10.

Müller AF, Strauss L, Greter M, Gast H, Recher M, Becher B, Fontana A.

Brain Behav Immun. 2015 Aug;48:78-85. doi: 10.1016/j.bbi.2015.02.027. Epub 2015 Mar 4.


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