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Items: 1 to 50 of 352

1.

A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients.

Pörings AS, Lowin T, Dufner B, Grifka J, Straub RH.

Sci Rep. 2019 Sep 13;9(1):13235. doi: 10.1038/s41598-019-49743-4.

2.

Learned immunosuppressive placebo response attenuates disease progression in a rodent model of rheumatoid arthritis.

Lückemann L, Stangl H, Straub RH, Schedlowski M, Hadamitzky M.

Arthritis Rheumatol. 2019 Sep 11. doi: 10.1002/art.41101. [Epub ahead of print]

PMID:
31509354
3.

Norepinephrine Inhibits Synovial Adipose Stem Cell Chondrogenesis via α2a-Adrenoceptor-Mediated ERK1/2 Activation.

El Bagdadi K, Zaucke F, Meurer A, Straub RH, Jenei-Lanzl Z.

Int J Mol Sci. 2019 Jun 26;20(13). pii: E3127. doi: 10.3390/ijms20133127.

4.

Increased pain and sensory hyperinnervation of the ligamentum flavum in patients with lumbar spinal stenosis.

Benditz A, Sprenger S, Rauch L, Weber M, Grifka J, Straub RH.

J Orthop Res. 2019 Mar;37(3):737-743. doi: 10.1002/jor.24251. Epub 2019 Feb 28.

PMID:
30747438
5.

A Promising New Approach for the Treatment of Inflammatory Pain: Transfer of Stem Cell-Derived Tyrosine Hydroxylase-Positive Cells.

Ebbinghaus M, Jenei-Lanzl Z, Segond von Banchet G, Stangl H, Gajda M, Straub RH, Schaible HG.

Neuroimmunomodulation. 2018;25(4):225-237. doi: 10.1159/000495349. Epub 2018 Dec 19.

PMID:
30566959
6.

Tempora mutantur et nos mutamur in illis [the times are changing, and we change in them].

Straub RH.

Brain Behav Immun. 2019 Jan;75:1-2. doi: 10.1016/j.bbi.2018.08.001. Epub 2018 Aug 29. Review. No abstract available.

PMID:
30171889
7.

TNF inhibits catecholamine production from induced sympathetic neuron-like cells in rheumatoid arthritis and osteoarthritis in vitro.

Herrmann M, Anders S, Straub RH, Jenei-Lanzl Z.

Sci Rep. 2018 Jun 25;8(1):9645. doi: 10.1038/s41598-018-27927-8.

8.

Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts.

Niedermair T, Schirner S, Seebröker R, Straub RH, Grässel S.

Sci Rep. 2018 Jun 15;8(1):9199. doi: 10.1038/s41598-018-27432-y.

9.

[New insights into the function of bone marrow].

Schett G, Bozec A, Bekeredjian-Ding I, Chang HD, David JP, Dörner T, Grässel S, Gunzer M, Manz R, Mei H, Mielenz D, Müller-Ladner U, Neumann E, Radbruch A, Richter W, Straub RH.

Z Rheumatol. 2018 May;77(Suppl 1):4-7. doi: 10.1007/s00393-018-0456-z. Review. German. No abstract available.

PMID:
29691692
10.

[Research consortium Neuroimmunology and pain in the research network musculoskeletal diseases].

Schaible HG, Chang HD, Grässel S, Haibel H, Hess A, Kamradt T, Radbruch A, Schett G, Stein C, Straub RH.

Z Rheumatol. 2018 May;77(Suppl 1):24-30. doi: 10.1007/s00393-018-0459-9. Review. German.

PMID:
29654392
11.

Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.

Sellmer A, Stangl H, Beyer M, Grünstein E, Leonhardt M, Pongratz H, Eichhorn E, Elz S, Striegl B, Jenei-Lanzl Z, Dove S, Straub RH, Krämer OH, Mahboobi S.

J Med Chem. 2018 Apr 26;61(8):3454-3477. doi: 10.1021/acs.jmedchem.7b01593. Epub 2018 Apr 6.

PMID:
29589441
12.

Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice.

Lamontain V, Schmid T, Weber-Steffens D, Zeller D, Jenei-Lanzl Z, Wajant H, Straub RH, Männel DN.

Cell Mol Immunol. 2019 Jan;16(1):65-74. doi: 10.1038/cmi.2017.138. Epub 2018 Jan 29.

PMID:
29375132
13.

Selective Activation of Tumor Necrosis Factor Receptor II Induces Antiinflammatory Responses and Alleviates Experimental Arthritis.

Fischer R, Proske M, Duffey M, Stangl H, Martinez GF, Peters N, Kraske A, Straub RH, Bethea JR, Kontermann RE, Pfizenmaier K.

Arthritis Rheumatol. 2018 May;70(5):722-735. doi: 10.1002/art.40413. Epub 2018 Mar 11.

14.

The brain and immune system prompt energy shortage in chronic inflammation and ageing.

Straub RH.

Nat Rev Rheumatol. 2017 Dec;13(12):743-751. doi: 10.1038/nrrheum.2017.172. Epub 2017 Oct 12. Review.

PMID:
29021568
15.

Psychoneuroimmunology-developments in stress research.

Straub RH, Cutolo M.

Wien Med Wochenschr. 2018 Mar;168(3-4):76-84. doi: 10.1007/s10354-017-0574-2. Epub 2017 Jun 9. Review.

PMID:
28600777
16.

Inflammation Is an Important Covariate for the Crosstalk of Sleep and the HPA Axis in Rheumatoid Arthritis.

Straub RH, Detert J, Dziurla R, Fietze I, Loeschmann PA, Burmester GR, Buttgereit F.

Neuroimmunomodulation. 2017;24(1):11-20. doi: 10.1159/000475714. Epub 2017 May 24.

PMID:
28535535
17.

Glucocorticoids and chronic inflammation.

Straub RH, Cutolo M.

Rheumatology (Oxford). 2016 Dec;55(suppl 2):ii6-ii14. Review.

PMID:
27856655
18.

Sympathetic nerve repulsion inhibited by designer molecules in vitro and role in experimental arthritis.

Kunath J, Delaroque N, Szardenings M, Neundorf I, Straub RH.

Life Sci. 2017 Jan 1;168:47-53. doi: 10.1016/j.lfs.2016.11.009. Epub 2016 Nov 14.

PMID:
27856318
19.

α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients.

Böhm M, Apel M, Lowin T, Lorenz J, Jenei-Lanzl Z, Capellino S, Dosoki H, Luger TA, Straub RH, Grässel S.

Biochem Pharmacol. 2016 Sep 15;116:89-99. doi: 10.1016/j.bcp.2016.07.003. Epub 2016 Jul 7.

PMID:
27396757
20.

Effects of treatment with etanercept versus methotrexate on sleep quality, fatigue and selected immune parameters in patients with active rheumatoid arthritis.

Detert J, Dziurla R, Hoff P, Gaber T, Klaus P, Bastian H, Braun T, Schellmann S, Penzel T, Fietze I, Loeschmann PA, Jaehnig P, Straub RH, Burmester GR, Buttgereit F.

Clin Exp Rheumatol. 2016 Sep-Oct;34(5):848-856. Epub 2016 Jun 22.

PMID:
27385076
22.

Increased extracellular water measured by bioimpedance and by increased serum levels of atrial natriuretic peptide in RA patients-signs of volume overload.

Straub RH, Ehrenstein B, Günther F, Rauch L, Trendafilova N, Boschiero D, Grifka J, Fleck M.

Clin Rheumatol. 2017 May;36(5):1041-1051. doi: 10.1007/s10067-016-3286-x. Epub 2016 Apr 26.

PMID:
27112146
23.

Predominance of synovial sensory nerve fibers in arthrofibrosis following total knee arthroplasty compared to osteoarthritis of the knee.

Koeck FX, Schmitt M, Baier C, Stangl H, Beckmann J, Grifka J, Straub RH.

J Orthop Surg Res. 2016 Feb 17;11:25. doi: 10.1186/s13018-016-0359-0.

24.

Peripheral elimination of the sympathetic nervous system stimulates immunocyte retention in lymph nodes and ameliorates collagen type II arthritis.

Klatt S, Stangl H, Kunath J, Lowin T, Pongratz G, Straub RH.

Brain Behav Immun. 2016 May;54:201-210. doi: 10.1016/j.bbi.2016.02.006. Epub 2016 Feb 9.

PMID:
26872423
25.

Chronic inflammatory systemic diseases: An evolutionary trade-off between acutely beneficial but chronically harmful programs.

Straub RH, Schradin C.

Evol Med Public Health. 2016 Jan 27;2016(1):37-51. doi: 10.1093/emph/eow001. Review.

26.

Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.

Lowin T, Apitz M, Anders S, Straub RH.

Arthritis Res Ther. 2015 Nov 14;17:321. doi: 10.1186/s13075-015-0845-5.

27.

Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis.

Muschter D, Schäfer N, Stangl H, Straub RH, Grässel S.

PLoS One. 2015 Oct 2;10(10):e0139726. doi: 10.1371/journal.pone.0139726. eCollection 2015.

28.

Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis.

Lowin T, Straub RH.

Arthritis Res Ther. 2015 Sep 6;17:226. doi: 10.1186/s13075-015-0743-x. Review.

29.

Association Between the Use of Oral Contraceptives and Patient-Reported Outcomes in an Early Arthritis Cohort.

Albrecht K, Callhoff J, Buttgereit F, Straub RH, Westhoff G, Zink A.

Arthritis Care Res (Hoboken). 2016 Mar;68(3):400-5. doi: 10.1002/acr.22667.

30.

Mimicking disruption of brain-immune system-joint communication results in collagen type II-induced arthritis in non-susceptible PVG rats.

Wolff C, Straub RH, Hahnel A, Randolf A, Wildmann J, Besedovsky HO, del Rey A.

Mol Cell Endocrinol. 2015 Nov 5;415:56-63. doi: 10.1016/j.mce.2015.08.005. Epub 2015 Aug 8.

PMID:
26265448
31.

Proinflammatory receptor switch from Gαs to Gαi signaling by β-arrestin-mediated PDE4 recruitment in mixed RA synovial cells.

Jenei-Lanzl Z, Zwingenberg J, Lowin T, Anders S, Straub RH.

Brain Behav Immun. 2015 Nov;50:266-274. doi: 10.1016/j.bbi.2015.07.020. Epub 2015 Jul 23.

PMID:
26212359
32.

Synovial fibroblasts integrate inflammatory and neuroendocrine stimuli to drive rheumatoid arthritis.

Lowin T, Straub RH.

Expert Rev Clin Immunol. 2015;11(10):1069-71. doi: 10.1586/1744666X.2015.1066674. Epub 2015 Jul 10. Review.

PMID:
26163397
33.

Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis.

Muschter D, Göttl C, Vogel M, Grifka J, Straub RH, Grässel S.

Arthritis Res Ther. 2015 Jun 24;17:169. doi: 10.1186/s13075-015-0684-4.

34.

Evolutionary medicine and bone loss in chronic inflammatory diseases--A theory of inflammation-related osteopenia.

Straub RH, Cutolo M, Pacifici R.

Semin Arthritis Rheum. 2015 Oct;45(2):220-8. doi: 10.1016/j.semarthrit.2015.04.014. Epub 2015 Apr 30. Review.

35.

CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women.

Stark K, Straub RH, Rovenský J, Blažičková S, Eiselt G, Schmidt M.

Arthritis Res Ther. 2015 Mar 11;17:56. doi: 10.1186/s13075-015-0574-9.

36.

Catecholaminergic-to-cholinergic transition of sympathetic nerve fibers is stimulated under healthy but not under inflammatory arthritic conditions.

Stangl H, Springorum HR, Muschter D, Grässel S, Straub RH.

Brain Behav Immun. 2015 May;46:180-91. doi: 10.1016/j.bbi.2015.02.022. Epub 2015 Feb 28.

PMID:
25736064
37.
38.
39.

Circadian rhythms in rheumatology--a glucocorticoid perspective.

Spies CM, Straub RH, Cutolo M, Buttgereit F.

Arthritis Res Ther. 2014 Nov 13;16 Suppl 2:S3. doi: 10.1186/ar4687. Review.

40.

Effects of 60-day bed rest with and without exercise on cellular and humoral immunological parameters.

Hoff P, Belavý DL, Huscher D, Lang A, Hahne M, Kuhlmey AK, Maschmeyer P, Armbrecht G, Fitzner R, Perschel FH, Gaber T, Burmester GR, Straub RH, Felsenberg D, Buttgereit F.

Cell Mol Immunol. 2015 Jul;12(4):483-92. doi: 10.1038/cmi.2014.106. Epub 2014 Nov 10.

41.

11β-hydroxysteroid dehydrogenase enzymes modulate effects of glucocorticoids in rheumatoid arthritis synovial cells.

Schmidt M, Straub RH.

Neuroimmunomodulation. 2015;22(1-2):40-5. doi: 10.1159/000362725. Epub 2014 Sep 12.

PMID:
25227721
42.

Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification.

Niedermair T, Kuhn V, Doranehgard F, Stange R, Wieskötter B, Beckmann J, Salmen P, Springorum HR, Straub RH, Zimmer A, Grifka J, Grässel S.

Matrix Biol. 2014 Sep;38:22-35. doi: 10.1016/j.matbio.2014.06.007. Epub 2014 Jul 22.

43.

Rheumatoid arthritis: Stress in RA: a trigger of proinflammatory pathways?

Straub RH.

Nat Rev Rheumatol. 2014 Sep;10(9):516-8. doi: 10.1038/nrrheum.2014.110. Epub 2014 Jul 8. No abstract available.

PMID:
25003764
44.

Increased expression of dopamine receptors in synovial fibroblasts from patients with rheumatoid arthritis: inhibitory effects of dopamine on interleukin-8 and interleukin-6.

Capellino S, Cosentino M, Luini A, Bombelli R, Lowin T, Cutolo M, Marino F, Straub RH.

Arthritis Rheumatol. 2014 Oct;66(10):2685-93. doi: 10.1002/art.38746.

45.

TRPV1, TRPA1, and TRPM8 channels in inflammation, energy redirection, and water retention: role in chronic inflammatory diseases with an evolutionary perspective.

Straub RH.

J Mol Med (Berl). 2014 Sep;92(9):925-37. doi: 10.1007/s00109-014-1175-9. Epub 2014 May 29. Review.

PMID:
24871046
46.

Norepinephrine inhibition of mesenchymal stem cell and chondrogenic progenitor cell chondrogenesis and acceleration of chondrogenic hypertrophy.

Jenei-Lanzl Z, Grässel S, Pongratz G, Kees F, Miosge N, Angele P, Straub RH.

Arthritis Rheumatol. 2014 Sep;66(9):2472-81. doi: 10.1002/art.38695.

47.

Inadequate corticosterone levels relative to arthritic inflammation are accompanied by altered mitochondria/cholesterol breakdown in adrenal cortex: a steroid-inhibiting role of IL-1β in rats.

Wolff C, Krinner K, Schroeder JA, Straub RH.

Ann Rheum Dis. 2015 Oct;74(10):1890-7. doi: 10.1136/annrheumdis-2013-203885. Epub 2014 May 7.

PMID:
24812291
48.

Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases.

Karrasch T, Obermeier F, Straub RH.

Horm Metab Res. 2014 Jun;46(6):445-51. doi: 10.1055/s-0034-1374587. Epub 2014 May 5.

PMID:
24799023
49.

Systemic disease sequelae in chronic inflammatory diseases and chronic psychological stress: comparison and pathophysiological model.

Straub RH.

Ann N Y Acad Sci. 2014 May;1318:7-17. doi: 10.1111/nyas.12409. Epub 2014 Apr 16.

PMID:
24738934
50.

Aromatase and regulation of the estrogen-to-androgen ratio in synovial tissue inflammation: common pathway in both sexes.

Capellino S, Straub RH, Cutolo M.

Ann N Y Acad Sci. 2014 May;1317:24-31. doi: 10.1111/nyas.12398. Epub 2014 Mar 28.

PMID:
24684533

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