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Items: 1 to 50 of 752

1.

Visual Attention Patterns Differ by Pictorial Health Warning Label Features.

Mercincavage M, Burdge J, Lochbuehler K, Souprountchouk V, McCullough AA, Strasser AA.

Tob Regul Sci. 2018 Nov;4(6):8-17. doi: 10.18001/TRS.4.6.2.

2.

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.

McRae HM, Garnham AL, Hu Y, Witkowski MT, Corbett MA, Dixon MP, May RE, Sheikh BN, Chiang W, Kueh AJ, Nguyen TA, Man K, Gloury R, Aubrey BJ, Policheni A, Di Rago L, Alexander WS, Gray DHD, Strasser A, Hawkins ED, Wilcox S, Gécz J, Kallies A, McCormack MP, Smyth GK, Voss AK, Thomas T.

Blood. 2019 Feb 12. pii: blood-2018-07-860726. doi: 10.1182/blood-2018-07-860726. [Epub ahead of print]

PMID:
30755422
3.

The Impact of E-Cigarette Warnings, Warning Themes and Inclusion of Relative Harm Statements on Young Adults' E-Cigarette Perceptions and Use Intentions.

Wackowski OA, Sontag JM, Hammond D, O'Connor RJ, Ohman-Strickland PA, Strasser AA, Villanti AC, Delnevo CD.

Int J Environ Res Public Health. 2019 Jan 10;16(2). pii: E184. doi: 10.3390/ijerph16020184.

4.

Association of Reduced Nicotine Content Cigarettes With Smoking Behaviors and Biomarkers of Exposure Among Slow and Fast Nicotine Metabolizers: A Nonrandomized Clinical Trial.

Mercincavage M, Lochbuehler K, Wileyto EP, Benowitz NL, Tyndale RF, Lerman C, Strasser AA.

JAMA Netw Open. 2018 Aug;1(4). pii: e181346. doi: 10.1001/jamanetworkopen.2018.1346. Epub 2018 Aug 24.

5.

Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein.

Chen M, Carmella SG, Sipe C, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami D, Hecht SS.

PLoS One. 2019 Jan 4;14(1):e0210104. doi: 10.1371/journal.pone.0210104. eCollection 2019.

6.

Nucleus accumbens neurochemistry in human anxiety: A 7 T 1H-MRS study.

Strasser A, Xin L, Gruetter R, Sandi C.

Eur Neuropsychopharmacol. 2019 Mar;29(3):365-375. doi: 10.1016/j.euroneuro.2018.12.015. Epub 2018 Dec 29.

PMID:
30600114
7.

BH3-Mimetic Drugs: Blazing the Trail for New Cancer Medicines.

Merino D, Kelly GL, Lessene G, Wei AH, Roberts AW, Strasser A.

Cancer Cell. 2018 Dec 10;34(6):879-891. doi: 10.1016/j.ccell.2018.11.004. Review.

PMID:
30537511
8.

Discussion of some "knowns" and some "unknowns" about the tumour suppressor p53.

Lieschke E, Wang Z, Kelly GL, Strasser A.

J Mol Cell Biol. 2018 Nov 29. doi: 10.1093/jmcb/mjy077. [Epub ahead of print]

PMID:
30496435
9.

Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development.

Aubrey BJ, Janic A, Chen Y, Chang C, Lieschke EC, Diepstraten ST, Kueh AJ, Bernardini JP, Dewson G, O'Reilly LA, Whitehead L, Voss AK, Smyth GK, Strasser A, Kelly GL.

Genes Dev. 2018 Nov 1;32(21-22):1420-1429. doi: 10.1101/gad.314286.118. Epub 2018 Oct 26.

PMID:
30366906
10.

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.

Taraborrelli L, Peltzer N, Montinaro A, Kupka S, Rieser E, Hartwig T, Sarr A, Darding M, Draber P, Haas TL, Akarca A, Marafioti T, Pasparakis M, Bertin J, Gough PJ, Bouillet P, Strasser A, Leverkus M, Silke J, Walczak H.

Nat Commun. 2018 Sep 25;9(1):3910. doi: 10.1038/s41467-018-06155-8.

11.

Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities.

Grabow S, Kueh AJ, Ke F, Vanyai HK, Sheikh BN, Dengler MA, Chiang W, Eccles S, Smyth IM, Jones LK, de Sauvage FJ, Scott M, Whitehead L, Voss AK, Strasser A.

Cell Rep. 2018 Sep 18;24(12):3285-3295.e4. doi: 10.1016/j.celrep.2018.08.048.

12.

Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial.

Hatsukami DK, Luo X, Jensen JA, al'Absi M, Allen SS, Carmella SG, Chen M, Cinciripini PM, Denlinger-Apte R, Drobes DJ, Koopmeiners JS, Lane T, Le CT, Leischow S, Luo K, McClernon FJ, Murphy SE, Paiano V, Robinson JD, Severson H, Sipe C, Strasser AA, Strayer LG, Tang MK, Vandrey R, Hecht SS, Benowitz NL, Donny EC.

JAMA. 2018 Sep 4;320(9):880-891. doi: 10.1001/jama.2018.11473.

PMID:
30193275
13.

Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis.

Salvamoser R, Brinkmann K, O'Reilly LA, Whitehead L, Strasser A, Herold MJ.

Cell Death Differ. 2018 Aug 28. doi: 10.1038/s41418-018-0188-2. [Epub ahead of print]

PMID:
30154447
14.

Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use.

Brennan MS, Chang C, Tai L, Lessene G, Strasser A, Dewson G, Kelly GL, Herold MJ.

Blood. 2018 Oct 11;132(15):1573-1583. doi: 10.1182/blood-2018-06-859405. Epub 2018 Aug 23.

PMID:
30139826
15.

The Importance of Filter Collection for Accurate Measurement of Cigarette Smoking.

Saddleson ML, Wileyto EP, Darwar R, Ware S, Strasser AA.

Tob Regul Sci. 2017 Jul;3(3):248-257. doi: 10.18001/TRS.3.3.1.

16.

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.

Baell JB, Leaver DJ, Hermans SJ, Kelly GL, Brennan MS, Downer NL, Nguyen N, Wichmann J, McRae HM, Yang Y, Cleary B, Lagiakos HR, Mieruszynski S, Pacini G, Vanyai HK, Bergamasco MI, May RE, Davey BK, Morgan KJ, Sealey AJ, Wang B, Zamudio N, Wilcox S, Garnham AL, Sheikh BN, Aubrey BJ, Doggett K, Chung MC, de Silva M, Bentley J, Pilling P, Hattarki M, Dolezal O, Dennis ML, Falk H, Ren B, Charman SA, White KL, Rautela J, Newbold A, Hawkins ED, Johnstone RW, Huntington ND, Peat TS, Heath JK, Strasser A, Parker MW, Smyth GK, Street IP, Monahan BJ, Voss AK, Thomas T.

Nature. 2018 Aug;560(7717):253-257. doi: 10.1038/s41586-018-0387-5. Epub 2018 Aug 1.

PMID:
30069049
17.

Radio Frequency Heating of Carbon Nanotube Composite Materials.

Sweeney CB, Moran AG, Gruener JT, Strasser AM, Pospisil MJ, Saed MA, Green MJ.

ACS Appl Mater Interfaces. 2018 Aug 15;10(32):27252-27259. doi: 10.1021/acsami.8b06268. Epub 2018 Aug 2.

PMID:
30039965
18.

Little and filtered cigars meet the legal definition of cigarettes and should be included in nicotine reduction regulation.

Byron MJ, Strasser AA, Delnevo CD.

Tob Control. 2018 Jul 18. pii: tobaccocontrol-2018-054410. doi: 10.1136/tobaccocontrol-2018-054410. [Epub ahead of print] No abstract available.

PMID:
30021871
19.

Efficacy of adding interoceptive exposure to intensive interdisciplinary treatment for adolescents with chronic pain: a randomized controlled trial.

Flack F, Stahlschmidt L, Dobe M, Hirschfeld G, Strasser A, Michalak J, Wager J, Zernikow B.

Pain. 2018 Nov;159(11):2223-2233. doi: 10.1097/j.pain.0000000000001321.

PMID:
29939961
20.

Temporal Effects of Message Congruency on Attention to and Recall of Pictorial Health Warning Labels on Cigarette Packages.

Lochbuehler K, Wileyto EP, Mercincavage M, Souprountchouk V, Burdge JZ, Tang KZ, Cappella JN, Strasser AA.

Nicotine Tob Res. 2018 Jun 16. doi: 10.1093/ntr/nty124. [Epub ahead of print]

PMID:
29917125
21.

DNA repair processes are critical mediators of p53-dependent tumor suppression.

Janic A, Valente LJ, Wakefield MJ, Di Stefano L, Milla L, Wilcox S, Yang H, Tai L, Vandenberg CJ, Kueh AJ, Mizutani S, Brennan MS, Schenk RL, Lindqvist LM, Papenfuss AT, O'Connor L, Strasser A, Herold MJ.

Nat Med. 2018 Jul;24(7):947-953. doi: 10.1038/s41591-018-0043-5. Epub 2018 Jun 11.

PMID:
29892060
22.

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility.

Nguyen QN, Zerafa N, Liew SH, Morgan FH, Strasser A, Scott CL, Findlay JK, Hickey M, Hutt KJ.

Cell Death Dis. 2018 May 23;9(6):618. doi: 10.1038/s41419-018-0633-7.

23.

Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK.

Ke FFS, Vanyai HK, Cowan AD, Delbridge ARD, Whitehead L, Grabow S, Czabotar PE, Voss AK, Strasser A.

Cell. 2018 May 17;173(5):1217-1230.e17. doi: 10.1016/j.cell.2018.04.036.

PMID:
29775594
24.

Pilot Experiment: The Effect of Added Flavorants on the Taste and Pleasantness of Mixtures of Glycerol and Propylene Glycol.

Rao PD, Nanding H, Strasser AA, Wise PM.

Chemosens Percept. 2018 Apr;11(1):1-9. doi: 10.1007/s12078-017-9231-9. Epub 2017 Jul 28.

PMID:
29755639
25.

Examining risk perceptions among daily smokers naïve to reduced nicotine content cigarettes.

Mercincavage M, Lochbuehler K, Villanti AC, Wileyto EP, Audrain-McGovern J, Strasser AA.

Nicotine Tob Res. 2018 Apr 28. doi: 10.1093/ntr/nty082. [Epub ahead of print]

PMID:
29718357
26.

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.

Peltzer N, Darding M, Montinaro A, Draber P, Draberova H, Kupka S, Rieser E, Fisher A, Hutchinson C, Taraborrelli L, Hartwig T, Lafont E, Haas TL, Shimizu Y, Böiers C, Sarr A, Rickard J, Alvarez-Diaz S, Ashworth MT, Beal A, Enver T, Bertin J, Kaiser W, Strasser A, Silke J, Bouillet P, Walczak H.

Nature. 2018 May;557(7703):112-117. doi: 10.1038/s41586-018-0064-8. Epub 2018 Apr 25.

27.

Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.

Liu R, King A, Bouillet P, Tarlinton DM, Strasser A, Heierhorst J.

Front Immunol. 2018 Mar 22;9:592. doi: 10.3389/fimmu.2018.00592. eCollection 2018.

28.

Whether to push or pull? Nicotine reduction and non-combusted alternatives - Two strategies for reducing smoking and improving public health.

Smith TT, Hatsukami DK, Benowitz NL, Colby SM, McClernon FJ, Strasser AA, Tidey JW, White CM, Donny EC.

Prev Med. 2018 Dec;117:8-14. doi: 10.1016/j.ypmed.2018.03.021. Epub 2018 Mar 29.

PMID:
29604326
29.

Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner.

O'Reilly LA, Putoczki TL, Mielke LA, Low JT, Lin A, Preaudet A, Herold MJ, Yaprianto K, Tai L, Kueh A, Pacini G, Ferrero RL, Gugasyan R, Hu Y, Christie M, Wilcox S, Grumont R, Griffin MDW, O'Connor L, Smyth GK, Ernst M, Waring P, Gerondakis S, Strasser A.

Immunity. 2018 Mar 20;48(3):570-583.e8. doi: 10.1016/j.immuni.2018.03.003.

PMID:
29562203
30.

How do thymic epithelial cells die?

Jain R, Mintern JD, Tan I, Dewson G, Strasser A, Gray DHD.

Cell Death Differ. 2018 May;25(5):1002-1004. doi: 10.1038/s41418-018-0093-8. Epub 2018 Mar 16. No abstract available.

PMID:
29549302
31.

Advancing Tobacco Product Warning Labels Research Methods and Theory: A Summary of a Grantee Meeting Held by the US National Cancer Institute.

Thrasher JF, Brewer NT, Niederdeppe J, Peters E, Strasser AA, Grana R, Kaufman AR.

Nicotine Tob Res. 2018 Feb 10. doi: 10.1093/ntr/nty017. [Epub ahead of print]

PMID:
29444268
32.

Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.

Dolles D, Hoffmann M, Gunesch S, Marinelli O, Möller J, Santoni G, Chatonnet A, Lohse MJ, Wittmann HJ, Strasser A, Nabissi M, Maurice T, Decker M.

J Med Chem. 2018 Feb 22;61(4):1646-1663. doi: 10.1021/acs.jmedchem.7b01760. Epub 2018 Feb 5.

PMID:
29400965
33.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

34.

The Effects of Varying Electronic Cigarette Warning Label Design Features On Attention, Recall, and Product Perceptions Among Young Adults.

Mays D, Villanti A, Niaura RS, Lindblom EN, Strasser AA.

Health Commun. 2019 Mar;34(3):317-324. doi: 10.1080/10410236.2017.1372050. Epub 2017 Dec 13.

PMID:
29236529
35.

How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?

Aubrey BJ, Kelly GL, Janic A, Herold MJ, Strasser A.

Cell Death Differ. 2018 Jan;25(1):104-113. doi: 10.1038/cdd.2017.169. Epub 2017 Nov 17. Review.

36.

Viewing BCL2 and cell death control from an evolutionary perspective.

Strasser A, Vaux DL.

Cell Death Differ. 2018 Jan;25(1):13-20. doi: 10.1038/cdd.2017.145. Epub 2017 Nov 3. Review.

37.

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.

Ottina E, Peperzak V, Schoeler K, Carrington E, Sgonc R, Pellegrini M, Preston S, Herold MJ, Strasser A, Villunger A.

Nat Commun. 2017 Oct 18;8(1):1028. doi: 10.1038/s41467-017-01022-4.

38.

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice.

Jain R, Sheridan JM, Policheni A, Heinlein M, Gandolfo LC, Dewson G, Smyth GK, Sansom SN, Fu NY, Visvader JE, Holländer GA, Strasser A, Gray DHD.

Blood. 2017 Dec 7;130(23):2504-2515. doi: 10.1182/blood-2017-03-771576. Epub 2017 Sep 29.

39.

Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.

Fitzsimmons L, Boyce AJ, Wei W, Chang C, Croom-Carter D, Tierney RJ, Herold MJ, Bell AI, Strasser A, Kelly GL, Rowe M.

Cell Death Differ. 2018 Feb;25(2):241-254. doi: 10.1038/cdd.2017.150. Epub 2017 Sep 29.

40.

Do current and former cigarette smokers have an attentional bias for e-cigarette cues?

Lochbuehler K, Wileyto EP, Tang KZ, Mercincavage M, Cappella JN, Strasser AA.

J Psychopharmacol. 2018 Mar;32(3):316-323. doi: 10.1177/0269881117728418. Epub 2017 Sep 19.

41.

Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms.

King A, Li L, Wong DM, Liu R, Bamford R, Strasser A, Tarlinton DM, Heierhorst J.

PLoS Genet. 2017 Sep 18;13(9):e1007010. doi: 10.1371/journal.pgen.1007010. eCollection 2017 Sep.

42.

Loss of BIM augments resistance of ATM-deficient thymocytes to DNA damage-induced apoptosis but does not accelerate lymphoma development.

Delbridge AR, Grabow S, Strasser A.

Cell Death Differ. 2017 Nov;24(11):1987-1988. doi: 10.1038/cdd.2017.138. Epub 2017 Sep 8. No abstract available.

43.

The combination of reduced MCL-1 and standard chemotherapeutics is tolerable in mice.

Brinkmann K, Grabow S, Hyland CD, Teh CE, Alexander WS, Herold MJ, Strasser A.

Cell Death Differ. 2017 Dec;24(12):2032-2043. doi: 10.1038/cdd.2017.125. Epub 2017 Aug 11.

44.

PTPN2 regulates T cell lineage commitment and αβ versus γδ specification.

Wiede F, Dudakov JA, Lu KH, Dodd GT, Butt T, Godfrey DI, Strasser A, Boyd RL, Tiganis T.

J Exp Med. 2017 Sep 4;214(9):2733-2758. doi: 10.1084/jem.20161903. Epub 2017 Aug 10.

45.

The ovarian reserve is depleted during puberty in a hormonally driven process dependent on the pro-apoptotic protein BMF.

Liew SH, Nguyen QN, Strasser A, Findlay JK, Hutt KJ.

Cell Death Dis. 2017 Aug 3;8(8):e2971. doi: 10.1038/cddis.2017.361.

46.

Perceived nicotine content of reduced nicotine content cigarettes is a correlate of perceived health risks.

Pacek LR, Joseph McClernon F, Denlinger-Apte RL, Mercincavage M, Strasser AA, Dermody SS, Vandrey R, Smith TT, Nardone N, Hatsukami DK, Koopmeiners JS, Kozink RV, Donny EC.

Tob Control. 2018 Jul;27(4):420-426. doi: 10.1136/tobaccocontrol-2017-053689. Epub 2017 Jul 22.

PMID:
28735272
47.

Considerations and Future Research Directions for E-Cigarette Warnings-Findings from Expert Interviews.

Wackowski OA, Hammond D, O'Connor RJ, Strasser AA, Delnevo CD.

Int J Environ Res Public Health. 2017 Jul 14;14(7). pii: E781. doi: 10.3390/ijerph14070781.

48.

Crowdsourced data collection for public health: A comparison with nationally representative, population tobacco use data.

Kraemer JD, Strasser AA, Lindblom EN, Niaura RS, Mays D.

Prev Med. 2017 Sep;102:93-99. doi: 10.1016/j.ypmed.2017.07.006. Epub 2017 Jul 8.

49.

The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL.

Delbridge AR, Aubrey BJ, Hyland C, Bernardini JP, Di Rago L, Garnier JM, Lessene G, Strasser A, Alexander WS, Grabow S.

Cell Death Dis. 2017 Jul 6;8(7):e2914. doi: 10.1038/cddis.2017.304.

50.

MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells.

Meyerovich K, Violato NM, Fukaya M, Dirix V, Pachera N, Marselli L, Marchetti P, Strasser A, Eizirik DL, Cardozo AK.

Diabetes. 2017 Sep;66(9):2446-2458. doi: 10.2337/db16-1252. Epub 2017 Jun 30.

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