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Items: 45

1.

Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin.

Farina AR, Cappabianca L, Ruggeri P, Di Ianni N, Ragone M, Merolle S, Sano K, Stracke ML, Horowitz JM, Gulino A, Mackay AR.

FEBS Lett. 2012 Oct 19;586(20):3681-91. doi: 10.1016/j.febslet.2012.08.026. Epub 2012 Sep 6.

2.

Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.

Im E, Motiejunaite R, Aranda J, Park EY, Federico L, Kim TI, Clair T, Stracke ML, Smyth S, Kazlauskas A.

Mol Cell Biol. 2010 May;30(10):2401-10. doi: 10.1128/MCB.01275-09. Epub 2010 Mar 15.

3.

Autotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration.

Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD.

Mol Cancer Res. 2010 Mar;8(3):309-21. doi: 10.1158/1541-7786.MCR-09-0288. Epub 2010 Mar 2.

4.

Novel point mutations attenuate autotaxin activity.

Koh E, Bandle RW, Roberts DD, Stracke ML, Clair T.

Lipids Health Dis. 2009 Feb 17;8:4. doi: 10.1186/1476-511X-8-4.

5.

Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells.

Ptaszynska MM, Pendrak ML, Bandle RW, Stracke ML, Roberts DD.

Mol Cancer Res. 2008 Mar;6(3):352-63. doi: 10.1158/1541-7786.MCR-07-0143.

6.

Sphingosine-1-phosphate initiates rapid retraction of pseudopodia by localized RhoA activation.

Koh E, Clair T, Hermansen R, Bandle RW, Schiffmann E, Roberts DD, Stracke ML.

Cell Signal. 2007 Jun;19(6):1328-38. Epub 2007 Jan 19.

PMID:
17307336
7.

Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors.

Koh E, Bandle R, Clair T, Roberts DD, Stracke ML.

Cancer Lett. 2007 May 18;250(1):53-62. Epub 2006 Dec 26.

PMID:
17189669
8.

L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin.

Clair T, Koh E, Ptaszynska M, Bandle RW, Liotta LA, Schiffmann E, Stracke ML.

Lipids Health Dis. 2005 Feb 28;4:5.

9.

Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate.

Clair T, Aoki J, Koh E, Bandle RW, Nam SW, Ptaszynska MM, Mills GB, Schiffmann E, Liotta LA, Stracke ML.

Cancer Res. 2003 Sep 1;63(17):5446-53.

10.

Autotaxin promotes motility via G protein-coupled phosphoinositide 3-kinase gamma in human melanoma cells.

Lee HY, Bae GU, Jung ID, Lee JS, Kim YK, Noh SH, Stracke ML, Park CG, Lee HW, Han JW.

FEBS Lett. 2002 Mar 27;515(1-3):137-40.

11.

Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor.

Nam SW, Clair T, Kim YS, McMarlin A, Schiffmann E, Liotta LA, Stracke ML.

Cancer Res. 2001 Sep 15;61(18):6938-44.

12.

Enzymatic activation of autotaxin by divalent cations without EF-hand loop region involvement.

Lee J, Jung ID, Nam SW, Clair T, Jeong EM, Hong SY, Han JW, Lee HW, Stracke ML, Lee HY.

Biochem Pharmacol. 2001 Jul 15;62(2):219-24.

PMID:
11389881
13.

A sensitive screening assay for secreted motility-stimulating factors.

Nam SW, Clair T, Schiffmann E, Liotta LA, Stracke ML.

Cell Motil Cytoskeleton. 2000 Aug;46(4):279-84.

PMID:
10962482
14.

Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells.

Nam SW, Clair T, Campo CK, Lee HY, Liotta LA, Stracke ML.

Oncogene. 2000 Jan 13;19(2):241-7.

15.

Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase.

Mulvaney PT, Stracke ML, Nam SW, Woodhouse E, O'Keefe M, Clair T, Liotta LA, Khaddurah-Daouk R, Schiffmann E.

Int J Cancer. 1998 Sep 25;78(1):46-52.

16.

Adenosine receptor mediates motility in human melanoma cells.

Woodhouse EC, Amanatullah DF, Schetz JA, Liotta LA, Stracke ML, Clair T.

Biochem Biophys Res Commun. 1998 May 29;246(3):888-94.

PMID:
9618307
17.

Nucleotide binding to autotaxin: crosslinking of bound substrate followed by lysC digestion identifies two labeled peptides.

Clair T, Krutzsch HC, Liotta LA, Stracke ML.

Biochem Biophys Res Commun. 1997 Jul 18;236(2):449-54.

PMID:
9240459
18.

Expression and transcriptional regulation of the PD-Ialpha/autotaxin gene in neuroblastoma.

Kawagoe H, Stracke ML, Nakamura H, Sano K.

Cancer Res. 1997 Jun 15;57(12):2516-21.

19.

Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities.

Clair T, Lee HY, Liotta LA, Stracke ML.

J Biol Chem. 1997 Jan 10;272(2):996-1001.

20.

Autotaxin, tumor motility-stimulating exophosphodiesterase.

Stracke ML, Clair T, Liotta LA.

Adv Enzyme Regul. 1997;37:135-44.

PMID:
9381968
21.
22.

Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin.

Lee HY, Clair T, Mulvaney PT, Woodhouse EC, Aznavoorian S, Liotta LA, Stracke ML.

J Biol Chem. 1996 Oct 4;271(40):24408-12.

23.

Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways.

Aznavoorian S, Stracke ML, Parsons J, McClanahan J, Liotta LA.

J Biol Chem. 1996 Feb 9;271(6):3247-54.

24.

Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells.

Lee HY, Murata J, Clair T, Polymeropoulos MH, Torres R, Manrow RE, Liotta LA, Stracke ML.

Biochem Biophys Res Commun. 1996 Jan 26;218(3):714-9.

PMID:
8579579
25.

Autotaxin is an N-linked glycoprotein but the sugar moieties are not needed for its stimulation of cellular motility.

Stracke ML, Arestad A, Levine M, Krutzsch HC, Liotta LA.

Melanoma Res. 1995 Aug;5(4):203-9.

PMID:
7496154
26.

Identification of a new immunoglobulin superfamily protein expressed in blood vessels with a heparin-binding consensus sequence.

Beckner ME, Krutzsch HC, Stracke ML, Williams ST, Gallardo JA, Liotta LA.

Cancer Res. 1995 May 15;55(10):2140-9.

27.

Stimulation and regulation of tumor cell motility in invasion and metastasis.

Levine MD, Liotta LA, Stracke ML.

EXS. 1995;74:157-79. Review.

PMID:
8527892
28.

cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases.

Murata J, Lee HY, Clair T, Krutzsch HC, Arestad AA, Sobel ME, Liotta LA, Stracke ML.

J Biol Chem. 1994 Dec 2;269(48):30479-84.

29.

The role of the extracellular matrix in tumor cell metastasis.

Stracke ML, Murata J, Aznavoorian S, Liotta LA.

In Vivo. 1994 Jan-Feb;8(1):49-58. Review.

PMID:
8054511
30.

Cytoskeletal agents inhibit motility and adherence of human tumor cells.

Stracke ML, Soroush M, Liotta LA, Schiffmann E.

Kidney Int. 1993 Jan;43(1):151-7.

31.

Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.

Margulies IM, Höyhtyä M, Evans C, Stracke ML, Liotta LA, Stetler-Stevenson WG.

Cancer Epidemiol Biomarkers Prev. 1992 Sep-Oct;1(6):467-74.

32.

Multi-step cascade of tumor cell metastasis.

Stracke ML, Liotta LA.

In Vivo. 1992 Jul-Aug;6(4):309-16. Review.

PMID:
1325842
33.

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.

Stracke ML, Krutzsch HC, Unsworth EJ, Arestad A, Cioce V, Schiffmann E, Liotta LA.

J Biol Chem. 1992 Feb 5;267(4):2524-9.

34.

A possible role for cysteine proteinase and its inhibitors in motility of malignant melanoma and other tumour cells.

Boike G, Lah T, Sloane BF, Rozhin J, Honn K, Guirguis R, Stracke ML, Liotta LA, Schiffmann E.

Melanoma Res. 1992 Jan-Feb;1(5-6):333-40.

PMID:
1422189
35.

Tumor cell motility.

Liotta LA, Stracke ML, Aznavoorian SA, Beckner ME, Schiffmann E.

Semin Cancer Biol. 1991 Apr;2(2):111-4. Review.

PMID:
1912521
36.

Cell motility, a principal requirement for metastasis.

Stracke ML, Aznavoorian SA, Beckner ME, Liotta LA, Schiffmann E.

EXS. 1991;59:147-62. Review.

PMID:
1833227
37.

Glycolysis as primary energy source in tumor cell chemotaxis.

Beckner ME, Stracke ML, Liotta LA, Schiffmann E.

J Natl Cancer Inst. 1990 Dec 5;82(23):1836-40.

PMID:
2174462
38.

Signal transduction for chemotaxis and haptotaxis by matrix molecules in tumor cells.

Aznavoorian S, Stracke ML, Krutzsch H, Schiffmann E, Liotta LA.

J Cell Biol. 1990 Apr;110(4):1427-38.

39.

The type I insulin-like growth factor receptor is a motility receptor in human melanoma cells.

Stracke ML, Engel JD, Wilson LW, Rechler MM, Liotta LA, Schiffmann E.

J Biol Chem. 1989 Dec 25;264(36):21544-9.

40.

Insulin-like growth factors stimulate chemotaxis in human melanoma cells.

Stracke ML, Kohn EC, Aznavoorian SA, Wilson LL, Salomon D, Krutzsch HC, Liotta LA, Schiffmann E.

Biochem Biophys Res Commun. 1988 Jun 30;153(3):1076-83.

PMID:
3291867
41.

Tumor invasion and metastases: biochemical mechanisms.

Liotta LA, Stracke ML.

Cancer Treat Res. 1988;40:223-38. Review. No abstract available.

PMID:
2908652
42.

Pertussis toxin inhibits stimulated motility independently of the adenylate cyclase pathway in human melanoma cells.

Stracke ML, Guirguis R, Liotta LA, Schiffmann E.

Biochem Biophys Res Commun. 1987 Jul 15;146(1):339-45.

PMID:
3496885
43.

Characterization of monoclonal antibodies produced by immunization with partially purified IgE receptor complexes.

Stracke ML, Basciano LK, Fischler C, Berenstein EH, Siraganian RP.

Mol Immunol. 1987 Apr;24(4):347-56.

PMID:
2443833
44.

Binding properties and histamine release in variants of rat basophilic leukemia cells with changes in the IgE receptor.

Stracke ML, Basciano LK, Siraganian RP.

Immunol Lett. 1987 Apr;14(4):287-92.

PMID:
2438212
45.

Regulation of prostaglandin formation by glucocorticoids and their second messenger, lipocortins.

Hirata F, Stracke ML, Schiffmann E.

J Steroid Biochem. 1987;27(4-6):1053-6. Review.

PMID:
2961939

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