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Items: 1 to 50 of 150

1.

VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.

English JG, Olsen RHJ, Lansu K, Patel M, White K, Cockrell AS, Singh D, Strachan RT, Wacker D, Roth BL.

Cell. 2019 Aug 8;178(4):1030. doi: 10.1016/j.cell.2019.07.036. No abstract available.

2.

VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.

English JG, Olsen RHJ, Lansu K, Patel M, White K, Cockrell AS, Singh D, Strachan RT, Wacker D, Roth BL.

Cell. 2019 Jul 25;178(3):748-761.e17. doi: 10.1016/j.cell.2019.05.051. Epub 2019 Jul 4. Erratum in: Cell. 2019 Aug 8;178(4):1030.

PMID:
31280962
3.

Early glucose abnormalities are associated with pulmonary inflammation in young children with cystic fibrosis.

Prentice BJ, Ooi CY, Strachan RE, Hameed S, Ebrahimkhani S, Waters SA, Verge CF, Widger J.

J Cyst Fibros. 2019 Apr 26. pii: S1569-1993(18)30897-X. doi: 10.1016/j.jcf.2019.03.010. [Epub ahead of print]

PMID:
31036487
4.

Reducing the radiation exposure from CT scanning in children with shunts: a nationwide survey and a departmental CT protocol.

Solth A, Mukerji N, Strachan R.

Br J Neurosurg. 2018 Oct;32(5):558-562. doi: 10.1080/02688697.2018.1485874. Epub 2018 Jul 18.

PMID:
30019596
5.

PAM-Antagonists: A Better Way to Block Pathological Receptor Signaling?

Kenakin T, Strachan RT.

Trends Pharmacol Sci. 2018 Aug;39(8):748-765. doi: 10.1016/j.tips.2018.05.001. Epub 2018 Jun 7. Review.

PMID:
29885909
6.

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.

Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, Strachan RT, Tribo AR, Pasternak GW, Carroll FI, Stevens RC, Cherezov V, Katritch V, Wacker D, Roth BL.

Cell. 2018 Jan 11;172(1-2):55-67.e15. doi: 10.1016/j.cell.2017.12.011. Epub 2018 Jan 4.

7.

Real-time symptom reporting during elective intracranial pressure monitoring using an interactive handset.

Coulter IC, Kemp C, Boddy IJS, Marsden SP, Mukerji N, Strachan RD.

Br J Neurosurg. 2018 Dec;32(6):694-696. doi: 10.1080/02688697.2017.1409878. Epub 2017 Nov 28. Erratum in: Br J Neurosurg. 2018 Feb;32(1):119.

PMID:
29183151
8.

Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.

Jean-Charles PY, Yu SM, Abraham D, Kommaddi RP, Mao L, Strachan RT, Zhang ZS, Bowles DE, Brian L, Stiber JA, Jones SN, Koch WJ, Rockman HA, Shenoy SK.

JCI Insight. 2017 Sep 7;2(17). pii: 95998. doi: 10.1172/jci.insight.95998. eCollection 2017 Sep 7.

9.

Age-related levels of fecal M2-pyruvate kinase in children with cystic fibrosis and healthy children 0 to 10years old.

Garg M, Leach ST, Pang T, Needham B, Coffey MJ, Katz T, Strachan R, Widger J, Field P, Belessis Y, Chuang S, Day AS, Jaffe A, Ooi CY.

J Cyst Fibros. 2018 Jan;17(1):109-113. doi: 10.1016/j.jcf.2017.07.011. Epub 2017 Jul 25.

PMID:
28754328
10.

Childhood interstitial lung diseases in immunocompetent children in Australia and New Zealand: a decade's experience.

Saddi V, Beggs S, Bennetts B, Harrison J, Hime N, Kapur N, Lipsett J, Nogee LM, Phu A, Suresh S, Schultz A, Selvadurai H, Sherrard S, Strachan R, Vyas J, Zurynski Y, Jaffé A.

Orphanet J Rare Dis. 2017 Jul 25;12(1):133. doi: 10.1186/s13023-017-0637-x.

11.

Age-dependent variation of fecal calprotectin in cystic fibrosis and healthy children.

Garg M, Leach ST, Coffey MJ, Katz T, Strachan R, Pang T, Needham B, Lui K, Ali F, Day AS, Appleton L, Moeeni V, Jaffe A, Ooi CY.

J Cyst Fibros. 2017 Sep;16(5):631-636. doi: 10.1016/j.jcf.2017.03.010. Epub 2017 Apr 14.

12.

Gravity-assisted valve (GAV) systems to prevent low-pressure headaches in patients with lumboperitoneal shunts.

Hussain MA, Strachan RD.

Br J Neurosurg. 2017 Aug;31(4):426-429. doi: 10.1080/02688697.2017.1285007. Epub 2017 Feb 6.

PMID:
28165764
13.

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library.

Ahn S, Kahsai AW, Pani B, Wang QT, Zhao S, Wall AL, Strachan RT, Staus DP, Wingler LM, Sun LD, Sinnaeve J, Choi M, Cho T, Xu TT, Hansen GM, Burnett MB, Lamerdin JE, Bassoni DL, Gavino BJ, Husemoen G, Olsen EK, Franch T, Costanzi S, Chen X, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1708-1713. doi: 10.1073/pnas.1620645114. Epub 2017 Jan 27.

14.

Gait comparison of unicompartmental and total knee arthroplasties with healthy controls.

Jones GG, Kotti M, Wiik AV, Collins R, Brevadt MJ, Strachan RK, Cobb JP.

Bone Joint J. 2016 Oct;98-B(10 Supple B):16-21.

15.

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.

Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ.

Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4.

16.

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.

Staus DP, Strachan RT, Manglik A, Pani B, Kahsai AW, Kim TH, Wingler LM, Ahn S, Chatterjee A, Masoudi A, Kruse AC, Pardon E, Steyaert J, Weis WI, Prosser RS, Kobilka BK, Costa T, Lefkowitz RJ.

Nature. 2016 Jul 21;535(7612):448-52. Epub 2016 Jul 13.

17.

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.

Kahsai AW, Wisler JW, Lee J, Ahn S, Cahill Iii TJ, Dennison SM, Staus DP, Thomsen AR, Anasti KM, Pani B, Wingler LM, Desai H, Bompiani KM, Strachan RT, Qin X, Alam SM, Sullenger BA, Lefkowitz RJ.

Nat Chem Biol. 2016 Sep;12(9):709-16. doi: 10.1038/nchembio.2126. Epub 2016 Jul 11.

18.

Wrong-level spinal surgery - 'never' again?

Mukerji N, Seetharam Manjunath Prasad K, Tizzard S, Aziz F, Varma A, Sinar E, Nath F, Strachan R, Kane P, Williamson S.

Br J Neurosurg. 2016;30(2):200-1. doi: 10.3109/02688697.2016.1155694. Epub 2016 Mar 11. No abstract available.

PMID:
26966921
19.

In-house development of a dedicated data acquisition and monitoring system for intracranial pressure, patient posture and patient symptoms in a regional neurosciences centre.

Marsden SP, Boddy IJ, Strachan RD, Chambers IR.

Physiol Meas. 2016 Feb;37(2):N1-10. doi: 10.1088/0967-3334/37/2/N1. Epub 2016 Jan 15.

PMID:
26767623
20.

Do antibiotic-impregnated external ventriculostomy catheters have a low infection rate in clinical practice? A retrospective cohort study.

Shekhar H, Kalsi P, Dambatta S, Strachan R.

Br J Neurosurg. 2016;30(1):64-9. doi: 10.3109/02688697.2015.1096903. Epub 2015 Oct 15.

PMID:
26469715
21.

Absence of back to school peaks in human rhinovirus detections and respiratory symptoms in a cohort of children with asthma.

Stelzer-Braid S, Tovey ER, Willenborg CM, Toelle BG, Ampon R, Garden FL, Oliver BG, Strachan R, Belessis Y, Jaffe A, Reddel HK, Crisafulli D, Marks GB, Rawlinson WD.

J Med Virol. 2016 Apr;88(4):578-87. doi: 10.1002/jmv.24371. Epub 2015 Sep 8.

PMID:
26331908
22.

A skull base air fistula secondary to ventriculoperitoneal shunt siphoning.

Das S, Hassan MF, Strachan R, Coulter I.

Br J Neurosurg. 2015;29(6):881-2. doi: 10.3109/02688697.2015.1071326. Epub 2015 Jul 24. No abstract available.

PMID:
26206303
23.

Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors.

Pironti G, Strachan RT, Abraham D, Mon-Wei Yu S, Chen M, Chen W, Hanada K, Mao L, Watson LJ, Rockman HA.

Circulation. 2015 Jun 16;131(24):2120-30. doi: 10.1161/CIRCULATIONAHA.115.015687. Epub 2015 May 20.

24.

CSF hydrothorax: An unusual cause of pleural effusion.

Cato-Addison WB, Strachan R.

Br J Neurosurg. 2015;29(4):600-2. doi: 10.3109/02688697.2015.1019420. Epub 2015 Mar 25.

PMID:
25807329
25.

Quantification of beta adrenergic receptor subtypes in beta-arrestin knockout mouse airways.

Hegde A, Strachan RT, Walker JK.

PLoS One. 2015 Feb 6;10(2):e0116458. doi: 10.1371/journal.pone.0116458. eCollection 2015.

26.

Intestinal inflammation and impact on growth in children with cystic fibrosis.

Dhaliwal J, Leach S, Katz T, Nahidi L, Pang T, Lee JM, Strachan R, Day AS, Jaffe A, Ooi CY.

J Pediatr Gastroenterol Nutr. 2015 Apr;60(4):521-6. doi: 10.1097/MPG.0000000000000683.

PMID:
25539196
27.

Rhinoviruses significantly affect day-to-day respiratory symptoms of children with asthma.

Tovey ER, Stelzer-Braid S, Toelle BG, Oliver BG, Reddel HK, Willenborg CM, Belessis Y, Garden FL, Jaffe A, Strachan R, Eyles D, Rawlinson WD, Marks GB.

J Allergy Clin Immunol. 2015 Mar;135(3):663-9.e12. doi: 10.1016/j.jaci.2014.10.020. Epub 2014 Dec 2.

PMID:
25476729
28.

Counting the cost of negligence in neurosurgery: Lessons to be learned from 10 years of claims in the NHS.

Hamdan A, Strachan RD, Nath F, Coulter IC.

Br J Neurosurg. 2015 Apr;29(2):169-77. doi: 10.3109/02688697.2014.971709. Epub 2014 Oct 21.

PMID:
25333197
29.

Observational study of the visibility of branded tobacco packaging and smoking at outdoor bars/cafes in Wellington, New Zealand.

Martin N, McHugh H, Murtagh J, Oliver-Rose C, Panesar D, Pengelly H, Rieper S, Schofield H, Singh V, Speed A, Strachan R, Tapsell TK, Trafford S, van Ryn S, Ward E, Whiting R, Wilson-van Duin M, Wu Z, Purdie G, van der Deen FS, Thomson G, Pearson AL, Wilson N.

N Z Med J. 2014 Oct 17;127(1404):27-36.

PMID:
25331309
30.

Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.

Tang W, Strachan RT, Lefkowitz RJ, Rockman HA.

J Biol Chem. 2014 Oct 10;289(41):28271-83. doi: 10.1074/jbc.M114.585067. Epub 2014 Aug 28.

31.

Routine but risky: a multi-centre analysis of the outcomes of cranioplasty in the Northeast of England.

Coulter IC, Pesic-Smith JD, Cato-Addison WB, Khan SA, Thompson D, Jenkins AJ, Strachan RD, Mukerji N.

Acta Neurochir (Wien). 2014 Jul;156(7):1361-8. doi: 10.1007/s00701-014-2081-1. Epub 2014 Apr 22.

PMID:
24752723
32.

Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR).

Strachan RT, Sun JP, Rominger DH, Violin JD, Ahn S, Rojas Bie Thomsen A, Zhu X, Kleist A, Costa T, Lefkowitz RJ.

J Biol Chem. 2014 May 16;289(20):14211-24. doi: 10.1074/jbc.M114.548131. Epub 2014 Mar 25.

33.

Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.

Staus DP, Wingler LM, Strachan RT, Rasmussen SG, Pardon E, Ahn S, Steyaert J, Kobilka BK, Lefkowitz RJ.

Mol Pharmacol. 2014 Mar;85(3):472-81. doi: 10.1124/mol.113.089516. Epub 2013 Dec 6.

34.

Unicompartmental knee arthroplasty enables near normal gait at higher speeds, unlike total knee arthroplasty.

Wiik AV, Manning V, Strachan RK, Amis AA, Cobb JP.

J Arthroplasty. 2013 Oct;28(9 Suppl):176-8. doi: 10.1016/j.arth.2013.07.036.

35.

T1-weighted sodium MRI of the articulator cartilage in osteoarthritis: a cross sectional and longitudinal study.

Newbould RD, Miller SR, Upadhyay N, Rao AW, Swann P, Gold GE, Strachan RK, Matthews PM, Taylor PC, Brown AP.

PLoS One. 2013 Aug 5;8(8):e73067. doi: 10.1371/journal.pone.0073067. Print 2013.

36.

Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor.

Weiss DR, Ahn S, Sassano MF, Kleist A, Zhu X, Strachan R, Roth BL, Lefkowitz RJ, Shoichet BK.

ACS Chem Biol. 2013 May 17;8(5):1018-26. doi: 10.1021/cb400103f. Epub 2013 Mar 21.

37.

Increased paediatric hospitalizations for empyema in Australia after introduction of the 7-valent pneumococcal conjugate vaccine.

Strachan RE, Snelling TL, Jaffé A.

Bull World Health Organ. 2013 Mar 1;91(3):167-73. doi: 10.2471/BLT.12.109231. Epub 2012 Dec 11. Erratum in: Bull World Health Organ. 2013 May 1;91(5):388.

38.

Expression of PPARγ and paraoxonase 2 correlated with Pseudomonas aeruginosa infection in cystic fibrosis.

Griffin PE, Roddam LF, Belessis YC, Strachan R, Beggs S, Jaffe A, Cooley MA.

PLoS One. 2012;7(7):e42241. doi: 10.1371/journal.pone.0042241. Epub 2012 Jul 31.

39.

T2* measurement of the knee articular cartilage in osteoarthritis at 3T.

Newbould RD, Miller SR, Toms LD, Swann P, Tielbeek JA, Gold GE, Strachan RK, Taylor PC, Matthews PM, Brown AP.

J Magn Reson Imaging. 2012 Jun;35(6):1422-9. doi: 10.1002/jmri.23598. Epub 2012 Feb 7.

40.

Reproducibility of sodium MRI measures of articular cartilage of the knee in osteoarthritis.

Newbould RD, Miller SR, Tielbeek JA, Toms LD, Rao AW, Gold GE, Strachan RK, Taylor PC, Matthews PM, Brown AP.

Osteoarthritis Cartilage. 2012 Jan;20(1):29-35. doi: 10.1016/j.joca.2011.10.007. Epub 2011 Oct 19.

41.

Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.

Lin R, Degan S, Theriot BS, Fischer BM, Strachan RT, Liang J, Pierce RA, Sunday ME, Noble PW, Kraft M, Brody AR, Walker JK.

Br J Pharmacol. 2012 Apr;165(7):2365-77. doi: 10.1111/j.1476-5381.2011.01725.x.

42.

Bacterial causes of empyema in children, Australia, 2007-2009.

Strachan RE, Cornelius A, Gilbert GL, Gulliver T, Martin A, McDonald T, Nixon GM, Roseby R, Ranganathan S, Selvadurai H, Smith G, Soto-Martinez M, Suresh S, Teoh L, Thapa K, Wainwright CE, Jaffe A; Australian Research Network in Empyema.

Emerg Infect Dis. 2011 Oct;17(10):1839-45. doi: 10.3201/eid1710.101825.

43.

Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ.

Sci Signal. 2011 Aug 9;4(185):ra51. doi: 10.1126/scisignal.2001707.

44.

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.

Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ.

Nature. 2011 Aug 21;477(7364):349-53. doi: 10.1038/nature10368.

45.

Prospective analysis of the trial period for spinal cord stimulation treatment for chronic pain.

Chincholkar M, Eldabe S, Strachan R, Brookes M, Garner F, Chadwick R, Gulve A, Ness J.

Neuromodulation. 2011 Nov-Dec;14(6):523-8; discussion 528-9. doi: 10.1111/j.1525-1403.2011.00384.x. Epub 2011 Aug 19.

PMID:
21854495
46.

Pleural fluid nucleic acid testing enhances pneumococcal surveillance in children.

Strachan RE, Cornelius A, Gilbert GL, Gulliver T, Martin A, McDonald T, Nixon G, Roseby R, Ranganathan S, Selvadurai H, Smith G, Soto-Martinez M, Suresh S, Teoh L, Thapa K, Wainwright CE, Jaffé A.

Respirology. 2012 Jan;17(1):114-9. doi: 10.1111/j.1440-1843.2011.02035.x.

PMID:
21848709
47.

Recommendations for managing paediatric empyema thoracis.

Strachan RE, Jaffé A; Thoracic Society of Australia and New Zealand.

Med J Aust. 2011 Jul 18;195(2):95. No abstract available.

PMID:
21770882
48.

Ultrasound preferred as the immediate preoperative investigation before three-pin rigid fixation.

Cowie CJ, Strachan R.

Childs Nerv Syst. 2011 Sep;27(9):1365-6; author reply 1367. doi: 10.1007/s00381-011-1520-z. Epub 2011 Jul 9. No abstract available.

PMID:
21744136
49.

A bedside assay to detect streptococcus pneumoniae in children with empyema.

Strachan RE, Cornelius A, Gilbert GL, Gulliver T, Martin A, McDonald T, Nixon GM, Roseby R, Ranganathan S, Selvadurai H, Smith G, Soto-Martinez M, Suresh S, Teoh L, Thapa K, Wainwright CE, Jaffé A; Australian Research Network in Empyema (ARNiE).

Pediatr Pulmonol. 2011 Feb;46(2):179-83. doi: 10.1002/ppul.21349. Epub 2010 Oct 20.

PMID:
20963842
50.

Recurrence of fourth ventricular choroid plexus papilloma with late occurrence of a spinal drop metastasis.

Palmer C, Kalsi P, Scoones D, Bradey N, Strachan R.

Br J Neurosurg. 2010 Aug;24(4):482-4. doi: 10.3109/02688697.2010.487135.

PMID:
20632883

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