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Items: 1 to 50 of 265

1.

Delayed Administration of Recombinant Plasma Gelsolin Improves Survival in a Murine Model of Penicillin-Susceptible and Penicillin-Resistant Pneumococcal Pneumonia.

Yang Z, Bedugnis A, Levinson S, Dinubile M, Stossel T, Lu Q, Kobzik L.

J Infect Dis. 2019 Sep 26;220(9):1498-1502. doi: 10.1093/infdis/jiz353.

PMID:
31287867
2.

Low Admission Plasma Gelsolin Concentrations Identify Community-acquired Pneumonia Patients at High Risk for Severe Outcomes.

Self WH, Wunderink RG, DiNubile MJ, Stossel TP, Levinson SL, Williams DJ, Anderson EJ, Bramley AM, Jain S, Edwards KM, Grijalva CG.

Clin Infect Dis. 2019 Sep 13;69(7):1218-1225. doi: 10.1093/cid/ciy1049.

PMID:
30561561
3.

Application of a public health strategy to large-scale point-of-care screening for sickle cell disease in rural sub-Saharan Africa.

Chunda-Liyoka C, Kumar AA, Sambo P, Lubinda F, Nchimba L, Humpton T, Okuku P, Miyanda C, Im J, Maguire K, Whitesides GM, Stossel TP.

Blood Adv. 2018 Nov 30;2(Suppl 1):1-3. doi: 10.1182/bloodadvances.2018GS112321. No abstract available.

4.

A guide to the anti-innovation "pharmaphobia" narrative for the aspiring innovator.

Stossel TP.

Surgery. 2017 Feb;161(2):305-307. doi: 10.1016/j.surg.2016.06.077. Review.

PMID:
28096036
5.

Gelsolin is an endogenous inhibitor of syncytiotrophoblast extracellular vesicle shedding in pregnancy.

Nadkarni NA, Rajakumar A, Mokhashi N, Burke SD, Rana S, Salahuddin S, Dang Q, Thadhani R, Krishnan R, Stossel TP, Karumanchi SA.

Pregnancy Hypertens. 2016 Oct;6(4):333-339. doi: 10.1016/j.preghy.2016.07.003. Epub 2016 Jul 11.

PMID:
27939478
7.

An adventitious interaction of filamin A with RhoGDI2(Tyr153Glu).

Song M, He Q, Berk BA, Hartwig JH, Stossel TP, Nakamura F.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):659-64. doi: 10.1016/j.bbrc.2015.12.044. Epub 2015 Dec 17.

8.

Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis.

Li-ChunHsieh K, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW.

J Neuroimmunol. 2015 Oct 15;287:36-42. doi: 10.1016/j.jneuroim.2015.08.006. Epub 2015 Aug 9.

9.

Plasma gelsolin improves lung host defense against pneumonia by enhancing macrophage NOS3 function.

Yang Z, Chiou TT, Stossel TP, Kobzik L.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1;309(1):L11-6. doi: 10.1152/ajplung.00094.2015. Epub 2015 May 8.

10.

From the bench to the field in low-cost diagnostics: two case studies.

Kumar AA, Hennek JW, Smith BS, Kumar S, Beattie P, Jain S, Rolland JP, Stossel TP, Chunda-Liyoka C, Whitesides GM.

Angew Chem Int Ed Engl. 2015 May 11;54(20):5836-53. doi: 10.1002/anie.201411741. Epub 2015 Apr 27. Review.

PMID:
25914299
11.

Response to clarifying the costs of conflicts of interest.

Stossel TP, Barton DW, Stell LK.

Int J Clin Pract. 2015 Mar;69(3):385-6. doi: 10.1111/ijcp.12617. No abstract available.

PMID:
25727804
12.

Evaluation of a density-based rapid diagnostic test for sickle cell disease in a clinical setting in Zambia.

Kumar AA, Chunda-Liyoka C, Hennek JW, Mantina H, Lee SY, Patton MR, Sambo P, Sinyangwe S, Kankasa C, Chintu C, Brugnara C, Stossel TP, Whitesides GM.

PLoS One. 2014 Dec 9;9(12):e114540. doi: 10.1371/journal.pone.0114540. eCollection 2014.

13.

Filamin A interaction with the CXCR4 third intracellular loop regulates endocytosis and signaling of WT and WHIM-like receptors.

Gómez-Moutón C, Fischer T, Peregil RM, Jiménez-Baranda S, Stossel TP, Nakamura F, Mañes S.

Blood. 2015 Feb 12;125(7):1116-25. doi: 10.1182/blood-2014-09-601807. Epub 2014 Oct 29.

14.

Documentation and localization of force-mediated filamin A domain perturbations in moving cells.

Nakamura F, Song M, Hartwig JH, Stossel TP.

Nat Commun. 2014 Aug 14;5:4656. doi: 10.1038/ncomms5656.

15.

After 20 years, industry critics bury skeptics, despite empirical vacuum.

Barton D, Stossel T, Stell L.

Int J Clin Pract. 2014 Jun;68(6):666-73. doi: 10.1111/ijcp.12438.

PMID:
24837089
16.

Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function.

Chen H, Chandrasekar S, Sheetz MP, Stossel TP, Nakamura F, Yan J.

Sci Rep. 2013;3:1642. doi: 10.1038/srep01642.

17.

In response: the ethics and value of professional medical writing assistance.

Weber MA, Fonseca R, Stossel TP.

Endocr Pract. 2013 Mar-Apr;19(2):379-80. No abstract available.

PMID:
23512399
18.

Association of Clinical Researchers and Educators a statement on relationships between physicians and industry.

Weber MA, Black HR, Fonseca R, Garber J, Gonzalez-Campoy JM, Kimmelstiel C, Markowitz AB, Nakayama D, Stell LK, Stossel TP.

Endocr Pract. 2012 Nov-Dec;18(6):1029-37. doi: 10.4158/EP12163.CO.

PMID:
22982801
19.

Commenting on ten recommendations for closing the credibility gap in reporting industry-sponsored clinical research.

Stossel TP, Stell LK.

Mayo Clin Proc. 2012 Sep;87(9):925-6; author reply 926. doi: 10.1016/j.mayocp.2012.06.020. No abstract available.

20.

Bias in high-tier medical journals concerning physician-academic relationships with industry.

Lesko R, Scott S, Stossel TP.

Nat Biotechnol. 2012 Apr 10;30(4):320-2. doi: 10.1038/nbt.2179. No abstract available.

PMID:
22491278
21.

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A.

Ehrlicher AJ, Nakamura F, Hartwig JH, Weitz DA, Stossel TP.

Nature. 2011 Sep 18;478(7368):260-3. doi: 10.1038/nature10430.

22.

Time to 'walk the walk' about industry ties to enhance health.

Stossel TP, Stell LK.

Nat Med. 2011 Apr;17(4):437-8. doi: 10.1038/nm0411-437.

PMID:
21475240
23.

Another dip into the muddy waters of COI.

Stell LK, Stossel TP.

Am J Bioeth. 2011 Jan;11(1):49-50. doi: 10.1080/15265161.2011.578200. No abstract available.

PMID:
21240813
24.

The filamins: organizers of cell structure and function.

Nakamura F, Stossel TP, Hartwig JH.

Cell Adh Migr. 2011 Mar-Apr;5(2):160-9. Epub 2011 Mar 1. Review.

25.

Actin filament length tunes elasticity of flexibly cross-linked actin networks.

Kasza KE, Broedersz CP, Koenderink GH, Lin YC, Messner W, Millman EA, Nakamura F, Stossel TP, Mackintosh FC, Weitz DA.

Biophys J. 2010 Aug 9;99(4):1091-100. doi: 10.1016/j.bpj.2010.06.025.

26.

Filamins and the potential of complexity.

Stossel TP.

Cell Cycle. 2010 Apr 15;9(8):1463. Epub 2010 Apr 15. No abstract available.

PMID:
20421719
27.

Cystic fibrosis transmembrane conductance regulator interacts with multiple immunoglobulin domains of filamin A.

Playford MP, Nurminen E, Pentikäinen OT, Milgram SL, Hartwig JH, Stossel TP, Nakamura F.

J Biol Chem. 2010 May 28;285(22):17156-65. doi: 10.1074/jbc.M109.080523. Epub 2010 Mar 29.

28.

The AAMC exhibits the behavior it condemns.

Stossel TP.

Am J Bioeth. 2010 Jan;10(1):26-7. doi: 10.1080/15265160903441095. No abstract available.

PMID:
20077333
29.

AACE and ACRE: Harmony of Interests.

Stossel TP.

Endocr Pract. 2009 Nov-Dec;15(7):671. No abstract available.

PMID:
20044323
30.

An active biopolymer network controlled by molecular motors.

Koenderink GH, Dogic Z, Nakamura F, Bendix PM, MacKintosh FC, Hartwig JH, Stossel TP, Weitz DA.

Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15192-7. doi: 10.1073/pnas.0903974106. Epub 2009 Aug 10.

31.

Nonlinear elasticity of stiff biopolymers connected by flexible linkers.

Kasza KE, Koenderink GH, Lin YC, Broedersz CP, Messner W, Nakamura F, Stossel TP, MacKintosh FC, Weitz DA.

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Apr;79(4 Pt 1):041928. Epub 2009 Apr 29.

PMID:
19518277
32.

Filamin A is essential for active cell stiffening but not passive stiffening under external force.

Kasza KE, Nakamura F, Hu S, Kollmannsberger P, Bonakdar N, Fabry B, Stossel TP, Wang N, Weitz DA.

Biophys J. 2009 May 20;96(10):4326-35. doi: 10.1016/j.bpj.2009.02.035.

33.

Plasma gelsolin and circulating actin correlate with hemodialysis mortality.

Lee PS, Sampath K, Karumanchi SA, Tamez H, Bhan I, Isakova T, Gutierrez OM, Wolf M, Chang Y, Stossel TP, Thadhani R.

J Am Soc Nephrol. 2009 May;20(5):1140-8. doi: 10.1681/ASN.2008091008. Epub 2009 Apr 23.

34.

Molecular basis of filamin A-FilGAP interaction and its impairment in congenital disorders associated with filamin A mutations.

Nakamura F, Heikkinen O, Pentikäinen OT, Osborn TM, Kasza KE, Weitz DA, Kupiainen O, Permi P, Kilpeläinen I, Ylänne J, Hartwig JH, Stossel TP.

PLoS One. 2009;4(3):e4928. doi: 10.1371/journal.pone.0004928. Epub 2009 Mar 18.

35.

Plasma gelsolin depletion and circulating actin in sepsis: a pilot study.

Lee PS, Patel SR, Christiani DC, Bajwa E, Stossel TP, Waxman AB.

PLoS One. 2008;3(11):e3712. doi: 10.1371/journal.pone.0003712. Epub 2008 Nov 12.

36.

Decreased levels of the gelsolin plasma isoform in patients with rheumatoid arthritis.

Osborn TM, Verdrengh M, Stossel TP, Tarkowski A, Bokarewa M.

Arthritis Res Ther. 2008;10(5):R117. doi: 10.1186/ar2520. Epub 2008 Sep 27.

37.

The discovery of statins.

Stossel TP.

Cell. 2008 Sep 19;134(6):903-5. doi: 10.1016/j.cell.2008.09.008.

39.

Has the hunt for conflicts of interest gone too far? Yes.

Stossel TP.

BMJ. 2008 Mar 1;336(7642):476. doi: 10.1136/bmj.39493.489213.AD. No abstract available.

40.

A biopsy of financial conflicts of interest in medicine.

Stossel TP.

Surgery. 2008 Feb;143(2):193-8. doi: 10.1016/j.surg.2007.11.013. No abstract available.

PMID:
18242335
41.

Structural basis of filamin A functions.

Nakamura F, Osborn TM, Hartemink CA, Hartwig JH, Stossel TP.

J Cell Biol. 2007 Dec 3;179(5):1011-25.

42.

Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity.

Weins A, Schlondorff JS, Nakamura F, Denker BM, Hartwig JH, Stossel TP, Pollak MR.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16080-5. Epub 2007 Sep 27.

43.

Divergent views on managing clinical conflicts of interest.

Stossel TP.

Mayo Clin Proc. 2007 Aug;82(8):1013-4; author reply 1014-5. No abstract available.

PMID:
17673071
44.

Conflicts of interest in dermatology: more than skin deep?

Stossel TP.

J Invest Dermatol. 2007 Aug;127(8):1829-30. No abstract available.

45.

International Society for Medical Publication Professionals (ISMPP) position statement: the role of the professional medical writer.

Norris R, Bowman A, Fagan JM, Gallagher ER, Geraci AB, Gertel A, Hirsch L, Ross PD, Stossel TP, Veitch K, Woods D.

Curr Med Res Opin. 2007 Aug;23(8):1837-40.

PMID:
17605897
46.

Overregulation of conflicts hinders medical progress.

Stossel TP.

Cleve Clin J Med. 2007 Mar;74 Suppl 2:S14-5; discussion S16-22.

PMID:
17469469
47.

In vitro function and phagocytosis of galactosylated platelet concentrates after long-term refrigeration.

Babic AM, Josefsson EC, Bergmeier W, Wagner DD, Kaufman RM, Silberstein LE, Stossel TP, Hartwig JH, Hoffmeister KM.

Transfusion. 2007 Mar;47(3):442-51.

PMID:
17319824
49.

Plasma gelsolin is a marker and therapeutic agent in animal sepsis.

Lee PS, Waxman AB, Cotich KL, Chung SW, Perrella MA, Stossel TP.

Crit Care Med. 2007 Mar;35(3):849-55.

PMID:
17205019
50.

Modifications of cellular responses to lysophosphatidic acid and platelet-activating factor by plasma gelsolin.

Osborn TM, Dahlgren C, Hartwig JH, Stossel TP.

Am J Physiol Cell Physiol. 2007 Apr;292(4):C1323-30. Epub 2006 Nov 29.

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