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Items: 15

1.

Structure-Based Design and Discovery of New M2 Receptor Agonists.

Fish I, Stößel A, Eitel K, Valant C, Albold S, Huebner H, Möller D, Clark MJ, Sunahara RK, Christopoulos A, Shoichet BK, Gmeiner P.

J Med Chem. 2017 Nov 22;60(22):9239-9250. doi: 10.1021/acs.jmedchem.7b01113. Epub 2017 Nov 13.

PMID:
29094937
2.

Development of molecular tools based on the dopamine D3 receptor ligand FAUC 329 showing inhibiting effects on drug and food maintained behavior.

Stößel A, Brox R, Purkayastha N, Hübner H, Hocke C, Prante O, Gmeiner P.

Bioorg Med Chem. 2017 Jul 1;25(13):3491-3499. doi: 10.1016/j.bmc.2017.04.036. Epub 2017 Apr 29.

3.

The experimental power of FR900359 to study Gq-regulated biological processes.

Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, Charpentier TH, Martz M, Butcher AJ, Slodczyk T, Armando S, Effern M, Namkung Y, Jenkins L, Horn V, Stößel A, Dargatz H, Tietze D, Imhof D, Galés C, Drewke C, Müller CE, Hölzel M, Milligan G, Tobin AB, Gomeza J, Dohlman HG, Sondek J, Harden TK, Bouvier M, Laporte SA, Aoki J, Fleischmann BK, Mohr K, König GM, Tüting T, Kostenis E.

Nat Commun. 2015 Dec 14;6:10156. doi: 10.1038/ncomms10156.

4.

A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.

Johansen LM, DeWald LE, Shoemaker CJ, Hoffstrom BG, Lear-Rooney CM, Stossel A, Nelson E, Delos SE, Simmons JA, Grenier JM, Pierce LT, Pajouhesh H, Lehár J, Hensley LE, Glass PJ, White JM, Olinger GG.

Sci Transl Med. 2015 Jun 3;7(290):290ra89. doi: 10.1126/scitranslmed.aaa5597.

PMID:
26041706
5.

FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.

Johansen LM, Brannan JM, Delos SE, Shoemaker CJ, Stossel A, Lear C, Hoffstrom BG, Dewald LE, Schornberg KL, Scully C, Lehár J, Hensley LE, White JM, Olinger GG.

Sci Transl Med. 2013 Jun 19;5(190):190ra79. doi: 10.1126/scitranslmed.3005471.

6.

Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones.

Stössel A, Schlenk M, Hinz S, Küppers P, Heer J, Gütschow M, Müller CE.

J Med Chem. 2013 Jun 13;56(11):4580-96. doi: 10.1021/jm400336x. Epub 2013 May 30.

PMID:
23631427
7.

Interferon-β therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever.

Smith LM, Hensley LE, Geisbert TW, Johnson J, Stossel A, Honko A, Yen JY, Geisbert J, Paragas J, Fritz E, Olinger G, Young HA, Rubins KH, Karp CL.

J Infect Dis. 2013 Jul 15;208(2):310-8. doi: 10.1093/infdis/jis921. Epub 2012 Dec 18.

8.

Inhibition of heat-shock protein 90 reduces Ebola virus replication.

Smith DR, McCarthy S, Chrovian A, Olinger G, Stossel A, Geisbert TW, Hensley LE, Connor JH.

Antiviral Res. 2010 Aug;87(2):187-94. doi: 10.1016/j.antiviral.2010.04.015. Epub 2010 May 7.

9.

Synthesis and biological evaluation of oxadiazole derivatives as inhibitors of soluble guanylyl cyclase.

von Wantoch Rekowski M, Pyriochou A, Papapetropoulos N, Stössel A, Papapetropoulos A, Giannis A.

Bioorg Med Chem. 2010 Feb;18(3):1288-96. doi: 10.1016/j.bmc.2009.12.027. Epub 2009 Dec 23.

PMID:
20036129
10.

The soluble guanylyl cyclase inhibitor NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability.

Morbidelli L, Pyriochou A, Filippi S, Vasileiadis I, Roussos C, Zhou Z, Loutrari H, Waltenberger J, Stössel A, Giannis A, Ziche M, Papapetropoulos A.

Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R824-32. doi: 10.1152/ajpregu.00222.2009. Epub 2009 Dec 23.

11.

Synthesis of cyclopamine using a biomimetic and diastereoselective approach.

Giannis A, Heretsch P, Sarli V, Stössel A.

Angew Chem Int Ed Engl. 2009;48(42):7911-4. doi: 10.1002/anie.200902520. No abstract available.

PMID:
19591183
12.

Novel Kaposi's sarcoma-associated herpesvirus homolog in baboons.

Whitby D, Stossel A, Gamache C, Papin J, Bosch M, Smith A, Kedes DH, White G, Kennedy R, Dittmer DP.

J Virol. 2003 Jul;77(14):8159-65.

13.

Prevalence of human herpesvirus 8 antibodies in young adults in Denmark (1976-1977).

Hjalgrim H, Lind I, Rostgaard K, Melbye M, Frisch M, Stossel A, Reimann K, Biggar RJ, Whitby D.

J Natl Cancer Inst. 2001 Oct 17;93(20):1569-71. No abstract available.

PMID:
11604481
14.

Identifying human herpesvirus 8 infection: performance characteristics of serologic assays.

Engels EA, Whitby D, Goebel PB, Stossel A, Waters D, Pintus A, Contu L, Biggar RJ, Goedert JJ.

J Acquir Immune Defic Syndr. 2000 Apr 1;23(4):346-54.

PMID:
10836758
15.

Local orbital forcing of antarctic climate change during the last interglacial

Kim SJ, Crowley TJ, Stossel A.

Science. 1998 May 1;280(5364):728-30.

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