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Items: 1 to 50 of 86

1.

High-throughput single-particle tracking reveals nested membrane domains that dictate KRasG12D diffusion and trafficking.

Lee Y, Phelps C, Huang T, Mostofian B, Wu L, Zhang Y, Tao K, Chang YH, Stork PJ, Gray JW, Zuckerman DM, Nan X.

Elife. 2019 Nov 1;8. pii: e46393. doi: 10.7554/eLife.46393. [Epub ahead of print]

2.

Proceedings of the fifth international RASopathies symposium: When development and cancer intersect.

Rauen KA, Schoyer L, Schill L, Stronach B, Albeck J, Andresen BS, Cavé H, Ellis M, Fruchtman SM, Gelb BD, Gibson CC, Gripp K, Hefner E, Huang WYC, Itkin M, Kerr B, Linardic CM, McMahon M, Oberlander B, Perlstein E, Ratner N, Rogers L, Schenck A, Shankar S, Shvartsman S, Stevenson DA, Stites EC, Stork PJS, Sun C, Therrien M, Ullian EM, Widemann BC, Yeh E, Zampino G, Zenker M, Timmer W, McCormick F.

Am J Med Genet A. 2018 Dec;176(12):2924-2929. doi: 10.1002/ajmg.a.40632. Epub 2018 Oct 10.

PMID:
30302932
3.

Phosphorylation of the C-Raf N Region Promotes Raf Dimerization.

Takahashi M, Li Y, Dillon TJ, Kariya Y, Stork PJS.

Mol Cell Biol. 2017 Sep 12;37(19). pii: e00132-17. doi: 10.1128/MCB.00132-17. Print 2017 Oct 1.

4.

Analysis of K-Ras Interactions by Biotin Ligase Tagging.

Ritchie C, Mack A, Harper L, Alfadhli A, Stork PJS, Nan X, Barklis E.

Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):225-239.

5.

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates.

Tillo SE, Xiong WH, Takahashi M, Miao S, Andrade AL, Fortin DA, Yang G, Qin M, Smoody BF, Stork PJS, Zhong H.

Cell Rep. 2017 Apr 18;19(3):617-629. doi: 10.1016/j.celrep.2017.03.070.

6.

Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP.

Takahashi M, Li Y, Dillon TJ, Stork PJ.

J Biol Chem. 2017 Jan 27;292(4):1449-1461. doi: 10.1074/jbc.M116.768986. Epub 2016 Dec 21.

7.
8.

ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells.

Obara Y, Nagasawa R, Nemoto W, Pellegrino MJ, Takahashi M, Habecker BA, Stork PJS, Ichiyanagi O, Ito H, Tomita Y, Ishii K, Nakahata N.

Cell Signal. 2016 Mar;28(3):177-189. doi: 10.1016/j.cellsig.2015.12.016. Epub 2015 Dec 29.

9.

Unexpected maturation of PI3K and MAPK-ERK signaling in fetal ovine cardiomyocytes.

Chattergoon NN, Louey S, Stork PJ, Giraud GD, Thornburg KL.

Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1216-25. doi: 10.1152/ajpheart.00833.2013. Epub 2014 Aug 15.

10.

Allosteric activation of functionally asymmetric RAF kinase dimers.

Hu J, Stites EC, Yu H, Germino EA, Meharena HS, Stork PJS, Kornev AP, Taylor SS, Shaw AS.

Cell. 2013 Aug 29;154(5):1036-1046. doi: 10.1016/j.cell.2013.07.046.

11.

Protein kinase A-dependent phosphorylation of Rap1 regulates its membrane localization and cell migration.

Takahashi M, Dillon TJ, Liu C, Kariya Y, Wang Z, Stork PJ.

J Biol Chem. 2013 Sep 27;288(39):27712-23. doi: 10.1074/jbc.M113.466904. Epub 2013 Aug 14.

12.

Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.

Li Y, Takahashi M, Stork PJ.

J Biol Chem. 2013 Sep 20;288(38):27646-57. doi: 10.1074/jbc.M113.463067. Epub 2013 Jul 26.

13.

B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells.

Dillon TJ, Takahashi M, Li Y, Tavisala S, Murray SE, Moran AE, Parker DC, Stork PJ.

Int Immunol. 2013 Apr;25(4):259-69. doi: 10.1093/intimm/dxs104. Epub 2013 Jan 18.

14.

N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence.

Wang Z, Liu Y, Takahashi M, Van Hook K, Kampa-Schittenhelm KM, Sheppard BC, Sears RC, Stork PJ, Lopez CD.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):312-7. doi: 10.1073/pnas.1201514110. Epub 2012 Dec 17.

15.

Mid-gestation ovine cardiomyocytes are vulnerable to mitotic suppression by thyroid hormone.

Chattergoon NN, Louey S, Stork P, Giraud GD, Thornburg KL.

Reprod Sci. 2012 Jun;19(6):642-9. doi: 10.1177/1933719111432860. Epub 2012 Mar 14.

16.

Thyroid hormone drives fetal cardiomyocyte maturation.

Chattergoon NN, Giraud GD, Louey S, Stork P, Fowden AL, Thornburg KL.

FASEB J. 2012 Jan;26(1):397-408. doi: 10.1096/fj.10-179895. Epub 2011 Oct 5.

17.

The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope.

Liu C, Takahashi M, Li Y, Dillon TJ, Kaech S, Stork PJ.

Mol Cell Biol. 2010 Aug;30(16):3956-69. doi: 10.1128/MCB.00242-10. Epub 2010 Jun 14.

18.

ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells.

Obara Y, Yamauchi A, Takehara S, Nemoto W, Takahashi M, Stork PJ, Nakahata N.

J Biol Chem. 2009 Aug 28;284(35):23564-73. doi: 10.1074/jbc.M109.027821. Epub 2009 Jul 6.

19.

[cAMP signaling for ERK activation in neuronal cells].

Obara Y, Nakahata N, Stork PJ.

Nihon Yakurigaku Zasshi. 2009 Feb;133(2):63-8. Review. Japanese. No abstract available.

PMID:
19218743
20.

Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2.

Liu C, Takahashi M, Li Y, Song S, Dillon TJ, Shinde U, Stork PJ.

Mol Cell Biol. 2008 Dec;28(23):7109-25. doi: 10.1128/MCB.01060-08. Epub 2008 Sep 29.

21.

The environmental fate of diuron under a conventional production regime in a sugarcane farm during the plant cane phase.

Stork PR, Bennett FR, Bell MJ.

Pest Manag Sci. 2008 Sep;64(9):954-63. doi: 10.1002/ps.1593.

PMID:
18470961
22.

Putting on the RITz.

Kaech S, Banker G, Stork P.

Sci STKE. 2007 Dec 11;2007(416):pe71.

PMID:
18073383
23.

The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells.

Obara Y, Horgan AM, Stork PJ.

J Neurochem. 2007 Apr;101(2):470-82. Epub 2007 Jan 24.

25.

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation.

Wang Z, Dillon TJ, Pokala V, Mishra S, Labudda K, Hunter B, Stork PJ.

Mol Cell Biol. 2006 Mar;26(6):2130-45.

26.

Use of audio-enhanced personal digital assistants for school-based data collection.

Trapl ES, Borawski EA, Stork PP, Lovegreen LD, Colabianchi N, Cole ML, Charvat JM.

J Adolesc Health. 2005 Oct;37(4):296-305.

27.

Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions.

Stork PJ, Dillon TJ.

Blood. 2005 Nov 1;106(9):2952-61. Epub 2005 Aug 2. Review.

28.

Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4.

Dillon TJ, Carey KD, Wetzel SA, Parker DC, Stork PJ.

Mol Cell Biol. 2005 May;25(10):4117-28.

29.

Directing NGF's actions: it's a Rap.

Stork PJ.

Nat Cell Biol. 2005 Apr;7(4):338-9. No abstract available.

PMID:
15803132
30.

Ras-independent activation of ERK signaling via the torso receptor tyrosine kinase is mediated by Rap1.

Mishra S, Smolik SM, Forte MA, Stork PJ.

Curr Biol. 2005 Feb 22;15(4):366-70.

31.

PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells.

Obara Y, Labudda K, Dillon TJ, Stork PJ.

J Cell Sci. 2004 Dec 1;117(Pt 25):6085-94. Epub 2004 Nov 16.

32.
33.

Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes.

Sundgren NC, Giraud GD, Schultz JM, Lasarev MR, Stork PJ, Thornburg KL.

Am J Physiol Regul Integr Comp Physiol. 2003 Dec;285(6):R1481-9. Epub 2003 Aug 28.

34.

Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy.

Dillon TJ, Karpitski V, Wetzel SA, Parker DC, Shaw AS, Stork PJ.

J Biol Chem. 2003 Sep 19;278(38):35940-9. Epub 2003 Jul 10.

35.

Does Rap1 deserve a bad Rap?

Stork PJ.

Trends Biochem Sci. 2003 May;28(5):267-75. Review.

PMID:
12765839
36.

Examining the mechanism of Erk nuclear translocation using green fluorescent protein.

Horgan AM, Stork PJ.

Exp Cell Res. 2003 May 1;285(2):208-20.

PMID:
12706116
37.

Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes.

Sundgren NC, Giraud GD, Stork PJ, Maylie JG, Thornburg KL.

J Physiol. 2003 May 1;548(Pt 3):881-91. Epub 2003 Mar 7.

38.

ERK signaling: duration, duration, duration.

Stork PJ.

Cell Cycle. 2002 Sep-Oct;1(5):315-7. No abstract available.

PMID:
12461291
39.

The requirement of specific membrane domains for Raf-1 phosphorylation and activation.

Carey KD, Watson RT, Pessin JE, Stork PJ.

J Biol Chem. 2003 Jan 31;278(5):3185-96. Epub 2002 Nov 21.

40.

Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.

Schmitt JM, Stork PJ.

J Biol Chem. 2002 Nov 8;277(45):43024-32. Epub 2002 Sep 6.

41.

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation.

Stork PJ, Schmitt JM.

Trends Cell Biol. 2002 Jun;12(6):258-66. Review.

PMID:
12074885
42.

Signaling pathways for PC12 cell differentiation: making the right connections.

Vaudry D, Stork PJ, Lazarovici P, Eiden LE.

Science. 2002 May 31;296(5573):1648-9. Review.

PMID:
12040181
43.
44.

Nonisotopic methods for detecting activation of small G proteins.

Carey KD, Stork PJ.

Methods Enzymol. 2002;345:383-97. No abstract available.

PMID:
11665622
45.
46.

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.

Schmitt JM, Stork PJ.

Mol Cell Biol. 2001 Jun;21(11):3671-83.

47.

Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2.

Florio T, Thellung S, Arena S, Corsaro A, Bajetto A, Schettini G, Stork PJ.

J Physiol Paris. 2000 May-Aug;94(3-4):239-50. Review.

PMID:
11088001
48.

CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

Carey KD, Dillon TJ, Schmitt JM, Baird AM, Holdorf AD, Straus DB, Shaw AS, Stork PJ.

Mol Cell Biol. 2000 Nov;20(22):8409-19.

49.

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

York RD, Molliver DC, Grewal SS, Stenberg PE, McCleskey EW, Stork PJ.

Mol Cell Biol. 2000 Nov;20(21):8069-83.

50.

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